Seyedvahid Khodaei

Seyedvahid Khodaei
McMaster University | McMaster · Department of Mechanical Engineering

About

19
Publications
4,240
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118
Citations

Publications

Publications (19)
Article
Full-text available
Accurate hemodynamic analysis is not only crucial for successful diagnosis of coarctation of the aorta (COA), but intervention decisions also rely on the hemodynamics assessment in both pre and post intervention states to minimize patient risks. Despite ongoing advances in surgical techniques for COA treatments, the impacts of extra-anatomic bypass...
Article
Background Despite ongoing advances in surgical techniques for coarctation of the aorta (COA) repair, the long‐term results are not always benign. Associated mixed valvular diseases (various combinations of aortic and mitral valvular pathologies) are responsible for considerable postoperative morbidity and mortality. We investigated the impact of C...
Article
Cardiovascular (CV) disease impacts tens of millions of people annually and carries a massive global economic burden. Continued advances in medical imaging, hardware and computational efficiency are leading to an increased interest in the field of cardiovascular computational modelling to help combat the devastating impact of CV disease. This revie...
Article
The optimal course of intervention for patients with coexisting coarctation of the aorta (COA) and mixed valvular disease (combinations of aortic and mitral valve pathologies, MVD) is an area of contention and uncertainty. To effectively evaluate risk status and create guidelines for intervention aimed at minimizing the progression of cardiovascula...
Article
Full-text available
Due to the high individual differences in the anatomy and pathophysiology of patients, planning individualized treatment requires patient-specific diagnosis. Indeed, hemodynamic quantification can be immensely valuable for accurate diagnosis, however, we still lack precise diagnostic methods for numerous cardiovascular diseases including complex (a...
Article
Full-text available
One of the most common acute and chronic cardiovascular disease conditions is aortic stenosis, a disease in which the aortic valve is damaged and can no longer function properly. Moreover, aortic stenosis commonly exists in combination with other conditions causing so many patients suffer from the most general and fundamentally challenging conditio...
Article
Aortic stenosis is an acute and chronic cardiovascular disease that often coexists with other complex valvular, ventricular and vascular diseases (C3VD). Transcatheter aortic valve replacement is an emerging less invasive intervention for patients with aortic stenosis. Although hemodynamics quantification is critical for accurate and early diagnosi...
Article
Full-text available
Coarctation of the aorta (COA) is a congenital narrowing of the proximal descending aorta. Although accurate and early diagnosis of COA hinges on blood flow quantification, proper diagnostic methods for COA are still lacking because fluid-dynamics methods that can be used for accurate flow quantification are not well developed yet. Most importantly...
Article
Full-text available
Background Mixed valvular disease (MVD), mitral regurgitation (MR) from pre‐existing disease in conjunction with paravalvular leak (PVL) following transcatheter aortic valve replacement (TAVR), is one of the most important stimuli for left ventricle (LV) dysfunction, associated with cardiac mortality. Despite the prevalence of MVD, the quantitative...
Article
Full-text available
In this article, the influences of non-uniform velocity profile attributable to slip boundary condition and viscosity of fluid on the dynamic instability of carbon nanotubes (CNTs) conveying fluid are investigated. The nonlocal elasticity theory and the Euler–Bernoulli beam theory are employed to derive partial differential equation of nanotubes co...
Article
Introduction: Most studies to date confirm that any increase in the needle insertion force increases the damage to the tissue. When it comes to brain tissue, even minor damage can cause a long-lasting traumatic brain injury. Thus there is a great demand for innovative minimally invasive needles among the medical community. In our previous studies a...
Poster
Full-text available
Recently there has been a substantial and growing interest in the medical community to develop innovative surgical needles for percutaneous interventional procedures. The answer to the challenge of developing advanced surgical needles could be found in nature. Insects such as honeybees, mosquitos, and horse flies have sophisticated sting mechanics...
Conference Paper
Full-text available
Needles are among the most common used instruments in surgery by medical professionals either for diagnosing the disease such as biopsy or for medical intervention such as drug delivery. Generally, needles are assumed to be minimally invasive, however it is desirable to decrease the insertion and pulling out force in order to prevent tissue damages...
Conference Paper
Full-text available
Biopsy involves removing a piece of tissues for further medical examination. Brain biopsy is generally performed using different techniques, such as open biopsy, stereotactic core biopsy, and needle biopsy. Open biopsy is the most common and the most invasive form of the brain biopsy. During the procedure, a piece of the skull is removed and the br...
Conference Paper
Although needle-based surgeries are considered as minimally invasive surgeries, the damage caused by the needle insertion in soft tissues, namely brain needs to be reduced. Any minor damage, swelling or bleeding in the brain tissue can lead to a long-lasting traumatic brain injury. Our approach to this challenge is to search for a proper solution i...
Conference Paper
Full-text available
Surgical needles are commonly used by medical professionals to reach target locations inside of the body for disease diagnosis or other medical interventions — such as biopsy, brachytheraphy, thermal ablation, and drug delivery [1, 2]. The effectiveness of these procedures depends on the accuracy with which the needle tips reach the targets, such a...
Article
Heart failure is one of the most important issues that has been investigated in recent research studies. Variations that occur in apparatus of mitral valve, such as chordae tendineaea rupture, can affect the valve function during ventricular contraction and lead to regurgitation from the left ventricle into the left atrium. One method for understan...
Conference Paper
Full-text available
Nowadays, heart failure is one of the most important issues to be considered in recent researches. One of the most important parts of heart is mitral valve, between left ventricle and left atrium. Variations that occur during ventricular contraction can impress mitral valve apparatus and lead to regurgitation from left ventricle to left atrium. In...

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Projects

Project (1)
Project
Modeling and computational analysis for cardiovascular system