Seyed Mehdi Razavi

University of Mohaghegh Ardabili | UMA · Department of Biology

The herbicidal, antifungal and antibacterial effects of carvone and its PLGA linked composite were studied. To synthesis of the composite, a ratio of 1: 2 of PLGA to carvone was used. The herbicidal activity of the composite and carvone was performed on seed germination and seedlings growth of some weeds. The antifungal test was performed using pot...

This study aims to green synthesis of sulfur nanoparticles (SNPs) and investigation on its effects at different doses on metabolic profiling of lettuce plants. Whereas previous works only focused on effects of SNPs on growth and stress tolerance of exposed plants, the current work investigates on impact of SNPs on metabolite profiling of plants. SN...

Physio-biochemical response and phytochemical variation in three West Asian genotypes (Torbetjam, Izmir and Gaziantep) of fennel (Foeniculum vulgare Mill) have been investigated in green house conditions to study the impact of water stress at 100, 50 and 35% of field capacity. In the Torbetjam genotype, chlorophyll content, plant growth and yield p...

In this study, the effect of green synthesized sulfur nanoparticle (SNP) at different concentration (0, 0.01, 0.1, 1 and 10 mg/ml) on some physiological, phytochemical and biochemical traits of lettuce plants was investigated. For the first time, SNP were green synthesized using Cinnamomum zeylanicum barks extract. Our results indicated that the tr...

Key message Piriformospora indica confers salt tolerance in tomato seedlings by increasing the uptake of nutrients such as N, P and Ca, improving K⁺/Na⁺ homoeostasis by regulating the expression of NHXs, SOS1 and CNGC15 genes, maintaining water status by regulating the expression of aquaporins. Abstract Piriformospora indica, an endophytic basidio...

Ultraviolet radiation can cause many serious problems for all living organisms. With a growing population, the UV sensitivity of crop plants presents a particular problem. To evaluate the suitability of growing in areas under UV irradiance, the influence of different doses of UV-B (3.042, 6.084 and 9.126 kJm −2 d −1) on the sugar beet (Beta vulgari...

The influence of endophyte fungus piriformospora indica on characteristics of the growth, water status, photosynthetic pigments concentration, gas exchange, and chlorophyll fluorescence of tomato plants under salt stress (0, 50, 100 and 150 mM) was studied in the greenhouse. Under salt stress, mycorrhizal tomato plants had higher dry weight of shoo...

Stevia rebaudiana Bert (Asteraceae) is a herbaceous plant with sweet leaves, which are the source of sweetener products. The present study focuses on effects of different combination of plant growth regulators on callus induction, callus cell growth and regeneration and volatile constituents from callus of stevia in tissue culture condition. The re...

More than 20% of irrigated land has been influenced by salt stress, decreasing crop production. In this research, we investigated the effect of different levels of salinity (0, 50, 100 and 150 mM NaCl) and the efficiency of Piriformospora indica on growth, biochemical traits, antioxidative defense system in tomato (Solanum lycopersicum L.). NaCl st...

Nowadays, allelopathic investigations have focused to identify action mechanisms of this compounds on target organisms in natural habitats. It may tend to introduce new natural herbicides and pesticides for replacing the synthetic ones. In the present study, the allelopathic effects of thymol on lettuce (Lactuca sativa L.) as a model plant were inv...

Nowadays, salinity has become an increasingly serious environmental issue that affects the growth and yield of a majority of plants. In the present work, the influences of Piriformospora indicia on gas exchange, water potential, osmolyte content, Na/K ratio and chlorophyll fluorescence of tomato plants under three salinity levels (0, 50, 100 and 15...

The volatile oil of the seeds of Eryngium bungei Boiss. (family Apiaceae), was obtained by hydrodistillation and analyzed by the GC-MS and the GC-FID. The analyses revealed at least 69 compounds representing 94 % of the total oil. The results showed that the oil was dominated by chrysanthenyl acetate (20.0 %), spathulenol (17.2 %), endo-isofenchol...

Stevia rebaudiana Bertoni is a perennial medicinal herb indigenous to tropical regions of South America. The present study evaluated some physiological changes of the plant under cold in the absence and the presence of polyamine conditions. The results showed photosynthetic pigments and photochemical efficiency of PSII reduced in cold treatment con...

The genus Nepeta L., with approximately 300 species, is one of the largest genera in the tribe Mentheae, subtribe Nepetinae of the Lamiaceae family. In the present work, pollen morphology of eight species of Nepeta was examined using scanning electron microscopy. The results indicated that the majority of the studied species were characterized by m...

Ferula orientalis (Apiaceae) is a well-known perennial herb growing wild in Iran used in traditional medicine. To perform phytochemical studies, dried ground roots of F. orientalis were sequentially Soxhlet-extracted using n-hexane, dichloromethane and methanol. A combination of vacuum liquid chromatography and preparative thin-layer chromatographi...

Hydrodistillation of the ground flowering tops of Leucanthemum vulgare (Asteraceae), collected from Heyran (Ardabil Province, Iran), afforded a greenish yellow oil (yield 0.15%, v/w), which was analyzed by the GC-MS and the GC-FID. The volatile oil comprised 47 compounds representing 90.3% of the oil. Caryophyllene oxide (21.2%), aromadendrene oxid...

Ferulago angulata (Schlecht) Boiss (Apiaceae) is a perennial herb distributed in the central parts of Iran. In this work, the essential oil of Ferulago angulata aerial parts collected from the central parts of Iran was obtained by using hydrodistillation analysed by GC and GC-MS. Air-dried and powdered plant roots were extracted with n-hexane, dich...

ABSTRACT Objective: The genus Artemisia (Asteraceae) comprises approximately 400 species of commonly perennial and fragrant herbs distributed in the northern temperate region of the world. Artemisia austriaca JACQ. is one of the most common species of the genus distributed from central Europe to Siberia, Turkey, and Iran. In Iran, the plant is indi...

Ferula persica wild (Apiaceae) is a perennial herb indigenous to Iran. It has been used in folk medicine for treatment of diabetes, lowering of blood pressure and for antispasmodic, carminative, laxative and expectorant effects in central Iran. Dried ground roots of F. persica (150 g) were extracted sequentially with n-hexane, dichloromethane and m...

Objective: The genus Artemisia (Asteraceae) comprises approximately 400 species of commonly perennial and fragrant herbs distributed in the northern temperate region of the world. Artemisia austriaca JACQ. is one of the most common species of the genus distributed from central Europe to Siberia, Turkey, and Iran. In Iran, the plant is indigenous to...

Zosima absinthifolia (Vent) Link (Apiaceae) is a perennial herb indigenous to Iran. It has been used as a medicinal plant from ancient time in Iran, Turkey and Pakistan. In the present work, air-dried and powdered plant roots were extracted with n-hexane, dichloromethane and methanol, respectively, using Soxhlet apparatus. The dichloromethane extra...

Background: Prangos ferulaceae (Apiaceae) is a perennial herb indigenous to Iran where it is used as a medicinal plant. In folk medicine, extracts of the roots and fruits of the plant have been used for the treatment of digestive disorders, healing scars, and to stop bleeding. In the present work, we report the presence of some phenolic compounds f...

Prangos ferulacea (Apiaceae) is a perennial herb with a distribution from East Europe to Middle East and Central Asia. The plant's leaves are used as animal fodder. Its fruits and roots possess biological traits that provide it with the potential to be used for medicinal purposes. The essential oils obtained through hydrodistillation from aerial pa...

Acroptilon repese (L.) Dc (Asteraceae) is a perennial herb with erect stems growing to 80 cm in height. It is a wide distributed plant that is native to Magnolia,Western Turkistan, Iran, Turkey and captain Asia and was introduced into America and Canada at the beginning of previous centaury. In the present work we study the chemical composition of...

Prangos pabularia Lindl. (Apiaceae) is a widespread perennial herb distributed from Russia to Iran, Turkey, India, Central Asia and Caucasian. It has been used in folk medicine from ancient times as a diuretic agent and a treatment for leukoplakia, digestive disorders, healing scars and stopping bleeding. In the present study, the composition of th...

Many researchers have shown that plant-derived polyphenolic compounds are helpful nutraceuticals in restraining various disorders such as neoplastic diseases. In this study two linear furanocoumarins, aviprin and aviprin-3″-O-D-glucopyranoside (A3G), were isolated from methanol extract of Prangos uloptera roots. The evaluation of free radical scave...

The volatile constituents obtained by hydrodistillation of the aerial parts of Prangos coryombosa at the vegetative and flowering stages were analysed by GC and GC-MS. Twenty-one and 28 compounds were identified from the oils obtained from the plant's aerial parts at the vegetative and flowering stages, respectively. The oil from the vegetative sta...

Coumarins are a well-known group of natural products distributed in the plant kingdom especially in the family Apiaceae with various biological activities. Isoarnottinin 4'-glucoside is a simple glycosylated coumarin found previously in a few genera of Apiaceae, and its biological activities have not been previously described in details. In the pre...

Malva sylvestris L. (Malvaceae), an annual plant, has been already commonly used as a medicinal plant in Iran. In the present work, we evaluate some bioactivities of the plant extracts. The aired-dried plant flowers and leaves were extracted by soxhlet apparatus with n-hexane, dichloromethane and methanol. The antimicrobial, cytotoxic, and phytotox...

In the last decades, application of synthetic toxins for control of weeds, pests and plant disease caused serious environmental problems. Allelopathy is regarded as a natural strategy in plants protecting them against environmental enemies and competing plants. This process involve plant secondary metabolites that suppress the growth and developmen...

The composition of the essential oils obtained from the flowering aerial parts of two populations of Thymus pubescens, collected from Mishov-Dagh, was determined by the GC-MS analyses. A total of 18 compounds, representing about 95% of the total oils, were identified in both samples of the essential oils. The essential oils of these two populations...

Furanocoumarins are well-known natural products that occur in the most evolved genera of Apiaceae family. This compounds were found to have cytotoxic, phytotoxic, photosensitizing, insecticidal, antibacterial and high anti-fungal effects. Aviprin is considered as a linear furanocoumarin substituted at C8 with an oxygenated prenyl residue. In this s...

The water-distilled essential oil from seeds of Chaerophyllum macrospermum was analyzed by GC-MS. Fifteen constituents were characterized. The major compounds were found to be E-β-farnesene (27.1 %), Z-β-ocimene (18.8 %), p-cymene (14.3 %), α-fenchyl acetate (12.7 %) and spathulenol (8.8 %). The comparision of our results with literature showed tha...

The water-distilled essential oil from seeds of Chaerophyllum macrospermum was analyzed by GC-MS. Fifteen constituents were characterized. The major compounds were found to be E-β-farnesene (27.1 %), Z-β-ocimene (18.8 %), p-cymene (14.3 %), α-fenchyl acetate (12.7 %) and spathulenol (8.8 %). The comparision of our results with literature showed tha...

Zosima absinthifolia belongs to the Apiaceae family and is found in Iran, Turkey, Iraq and different countries of the Caucasus, Middle East and Central Asia. The fruits are used as food flavoring and as a food spice in Iran. In the present work, an n-hexane extract of the plant seeds was purified by vacuum liquid chromatography and preparative TLC...

A known furanocoumarin, 8-geranyloxy psoralen, was isolated from n-hexane extract of Prangos uloptera roots by the TLC method. Its structure was determined by comparison of the spectral data with the literature. Cytotoxic effects of the isolated compound were determined by MTT and Tripan blue assays. The antioxidant and antimicrobial potential of t...

Crambe orientalis L. (Brassicaceae), a perennial herb, is indigenous to Iran. The essential oils of flowering tops and leaves of the plant were evaluated by GC-MS. Our results showed that while 2-methyl-5-hexenitrile (19.5%) and benzyl cyanide (16.9%) were the major components of flowering tops oil, the oil of the leaves was dominated by octyl-acet...

The chemical composition of essential oil obtained by hydrodistillation from the dried fruits of Zosima absinthifolia was analysed by GC-MS. Twenty-four compounds were characterised in the oil. The major components of the oil were octyl acetate (87.48%), octyl octanoate (5.03%) and 1-octanol (2.37%). The oil showed modest to weak allelopatic effect...

The hydrodistillated essential oils from leaves and fruits of Ecballium elaterium were analysed by GC-MS. Octyl octanoate (30.0%), 3-(6,6- dimethyl-5-oxohept-2-enyl)-cyclohexanone (20.4%) and hexahydro farnesyl acetone (19.1%) were the main components among 21 constituents characterised in the leaf oil. Twenty-one compounds were also identified in...

Prangos uloptera DC. (Apiaceae) is indigenous to Iran. It has been used from ancient times for treatment of leukoplakia, digestive disorders and healing scars. In this article, we focus on the various biological screening techniques currently being used to evaluate the biological effects of the plant root extracts. Our results show that dichloromet...

In the current investigation, the influence of the plant growth stages (prior to emergence of flower heads or vegetative, anthesis and fruiting) on the essential oil content and composition in the aerial parts of Prangos uloptera DC. was studied. Quantitative and qualitative differences were found among oil of aerial parts at three phenological sta...

The seed dormancy of Prangos ferulaceae (Apiaceae) has been studied with treatment the seeds by soaking, scarification, cold and warm stratification, alternating temperatures and GA3. Our results showed that the seeds dormancy can be broken by cold stratification at 5°C and 12°C which induced germination up to 35 and 40%, respectively. Alternating...

The volatile oils of stem, umbels, fruits and roots of Astrodaucus orientalis (L.) Drude (Apiaceae) growing wild in Iran were obtained by hydro-distillation and analyzed by GC-MS. The main components of the oils from the stem were sabinene (23.1%), a -pinene (16.4%) and fenchyl-acetate (7.5%). Sabinene (25.6%), b -pinene (22.3%) and a -copaene (16....

The hydrodistilled essential oils of fruits and umbels of Prangos ferulaceae (L.) Lindl growing in Iran were analysed by gas chromatograph-mass spectrometer. Six compounds, comprising 93.7 and 94.7% of the total fruits and umbels oils, were identified, respectively. alpha-Pinene and cis-ocimene are the major components of the oils. The essential oi...

Cytotoxic, phytotoxic, antimicrobial and antioxidant effects of quercetin 3-O-glucoside (Q3G) isolated by HPLC from aerial parts of Prangos ferulaceae was studied by MTT assay, lettuce germination assay, disk diffusion and DPPH method. Our results showed that Q3G exhibits high antioxidant effect with RC(50) of 22 microg/mL, it has low cytotoxicity...

Zosima absinthifolia is a perennial herb which is distributed from Turkey to East Asia and Iran. It's fruits are used as a food spice in Iran and Turkey. In this work, we will study some biological activities of the fruits of the plant. The MTT assay indicated that methanol extract of the plant exhibited significant cytotoxic effects. In the DPPH a...

Crambe orientalis (Brassicaceae) is a perennial herb growing wild in Iran. Cytotoxic, antioxidant, antimicrobial and phttotoxic effects of the plant leaves extracts have been evaluated by MTT, DPPH, Disc diffusion and lettuce assays, respectively. Our results showed that dichloromethane and methanol extracts of the plant leaves exhibited high cytot...

Inhibition of the cell growth or induction of cell death is the most promising area in cancer therapy. The induction of apoptosis by dichloromethane extract of Prangos uloptera was evaluated on the McCoy cell line. This plant's roots, aerial parts and fruit have medicinal value. Cell growth inhibitory and cell cytotoxicity effects of the extract we...

Three new coumarins, 6-O-[β-d-apiofuranosyl-(1→6)-β-d-glucopyranosyl]-prenyletin, 3″-O-[β-d-apiofuranosyl-(1→6)-β-d-glucopyranosyl]-oxypeucedanin hydrate and 2″-O-[β-d-apiofuranosyl-(1→6)-β-d-glucopyranosyl]-oxypeucedanin hydrate, together with six known coumarins, 3″-O-[β-d-apiofuranosyl-(1→6)-β-d-glucopyranosyl]-heraclenol, 3″-O-(β-d-glucopyranos...

Seven free-radical-scavenging phenolic compounds including five flavonoids, rutin (1), chrysoeriol 7-O-rutinoside (2), kaempferol 3-O-glucoside (3), chrysoeriol 7-O-glucoside (4) and naringenin (5), and two phenylethanoid glycosides, forsythoside B (6) and acteoside (7) were isolated from the methanol extract of the aerial parts of the Iranian medi...

Phytochemical studies on the aerial parts of Prangos uloptera, an endemic Iranian species of the genus Prangos, yielded five coumarins, xanthotoxin (1), prangenin (2), scopoletin (3), deltoin (4) and prangolarin (5). The structures of these coumarins were elucidated by spectroscopic means, and the antioxidant potential of 1-5 was evaluated by the D...

The chemical composition of Prangos scabra and component activities have been investigated by several authors [1‐6]. The air-dried fruits and inflorescence of Prangos scabra yielded 1.6% and 0.3% of a pale yellow oil, respectively. In the DPPH assay, the essential oils of the fruits (EOF) and inflorescence (EOI) exhibited weak free radical scavengi...

The composition of the essential oils of the umbels and fruit of Prangos uloptera, an indigenous Iranian medicinal plant, was determined by GC-MS analyses. A total of 10 and 18 compounds were identified, respectively, from the essential oils of the umbels and the fruit. The identified compounds represented, respectively, 93.2% and 83.0% of the tota...

Objective(s)As an important class of natural products, coumarins exhibit many biological activities and the diversity of their bioactivity is so huge that the pharmacological promiscuity has been applied on their case. Oxypeucedanine also named as prangolarin is a linear furanocoumarin with an oxygenated prenylated substitution at C-5 of the nucleu...