Seyed vahid Hosseini

Shiraz University of Medical Sciences | SUMS · Colorectal Research Center

Background It is estimated that over 1.9 billion people suffer from overweight worldwide, among whom 600 million people are classified as obese. Obesity can result in many health problems. One of them is balance control insufficiency. Obesity treatment and management may include a combination of diet modification, appropriate physical activity, beh...

Purpose This study aimed to investigate the efficacy of hydrocortisone enema in preventing radiation proctitis in patients with rectal cancer undergoing short-course radiotherapy (SCRT). Methods This phase II randomized controlled trial enrolled patients with newly diagnosed locally advanced rectal cancer (clinically staged T3–4 and/or N1–2M0). Pa...

To date, no comprehensive study has been conducted to assess the prevalence of kidney diseases in Iran. With the establishment of the Prospective Epidemiological Research Studies in IrAN (the PERSIAN cohort) across various provinces, we aim to address this gap using data from the baseline phase of this cohort study. In this large-scale population-b...

Aim Very few studies have compared laparoscopic pelvic organ prolapse suspension (POPS) and laparoscopic ventral mesh rectopexy (LVMR) in the treatment of rectal prolapse, particularly regarding the comparison of improvement rates in obstructed defecation syndrome (ODS). This study aimed to compare the anatomical and functional outcomes of these tw...

ABSTRACT Background: The rise in morbid obesity has prompted the development of new bariatric surgery techniques, including the Single Anastomosis Sleeve Jejunal Bypass (SASJ). This study aimed to compare the effects of SASJ and conventional Sleeve Gastrectomy (SG) on weight loss, biochemical markers, and comorbidities and to provide essential insi...

Background: Although bariatric surgery has been introduced as a therapeutic option for patients with obesity, there is still debate on the choice of procedure. Objectives: This study aimed to compare two types of bariatric surgeries in patients with obesity: Sleeve gastrectomy (SG) and single anastomosis sleeve ileal (SASI) bypass. Methods: This ob...

Background This study assessed the prevalence of gastroesophageal reflux disease (GERD) in a general adult population in Iran. The association between GERD and various factors was also evaluated. Methods We performed a cross-sectional study on 163,018 individuals aged over 35 who were enrolled in the PERSIAN cohort. GERD was defined as the occurre...

Background: There is strong evidence that obesity, especially morbid obesity, is associated with serious and dangerous physical illnesses, and that weight loss in these patients can improve their social functioning, quality of life, and mental health. Objectives: The goal of this study was to evaluate eating behaviors, physical activity, and weight...

Original Article Background: Anastomotic leakage (AL) is the main complication of colorectal surgeries. Recent studies have assessed the effects of the ghost ileostomy on preventing complications related to a defunctioning stoma (DS) in high-risk anastomoses. In this study, we aimed to review patients who underwent ghost ileostomy and assess their...

Introduction: Total proctocolectomy with ileal pouch-anal anastomosis (IPAA) is a surgical procedure performed on patients with ulcerative colitis (UC) to avoid the need for permanent stoma. The objective of this study was to assess the quality of life and fecal incontinence in UC patients after IPAA and compare the quality of life among different...

Purpose The Kharameh cohort study (KHCS) is one branch of the ‘Prospective Epidemiological Research Studies in Iran’, located in the south of Iran. The enrolment phase of KHCS spanned from April 2015 to March 2017, during which urban and rural residents of Kharameh were enrolled in the study. KHCS aims to investigate the incidence of non-communicab...

To investigate the effects of thymidylate synthase (TS) 3'UTR genotype on promotor methylation of tumor-related genes in 22 patients with sporadic colorectal cancer (CRC) from southern Iran. We evaluated the correlations of TS 3'UTR genotype with promoter methylation of hTERT, hMLH1, MSH2, MMP2, CDH1, p14, p16, and p21 genes in CRC patients. The po...

Diabetes is an important risk factor for cardiovascular disease. The purpose of this study was to explore the role of diabetes and prediabetes in the risk of cardiovascular disease. This prospective study was performed on three groups of non-diabetic (n = 7291), prediabetic (n = 438), and diabetic (n = 1713) in the age range of 40–70 years in Khara...

Introduction: Colorectal cancer remains a significant health challenge, particularly in its advanced Stage III. Timely forecasting of recurrence and metastasis in these patients is crucial for optimizing postoperative care and treatment strategies. The aim of this study is to predict the likelihood of recurrence and metastasis in stage III colorect...

Background Transanal Endoscopic Microsurgery (TEM) is a minimally invasive method for management of different proctologic conditions. Despite widespread use of this method, it is not used widely in Iran. This report is about to describe the application of TEM in managing different proctologic conditions in a tertiary colorectal referral center in I...

Background and Aims Hypertension and abnormal liver enzymes are common health issues that frequently coexist, and recent research has suggested a possible association between them, warranting further investigation. Therefore, the aim of this study is to explore the relationship between liver enzymes and hypertension. Methods This prospective cohor...

Introduction: Managing nutritional deficiencies is an essential component in the treatment of severe obesity. Vitamin D deficiency is often reported in investigations in severe obese cohorts. However, no prior study has summarized findings on this topic. Consequently, the aim of this systematic review and meta-analysis was to investigate the 25-hy...

Background: Oxidative stress contributes to the development of cardiovascular disease. Tools for evaluating the anti-inflammatory and antioxidative characteristics of an individual’s diet as a whole may be valuable for assessing the combined effects of dietary antioxidants on health. This population-based study aimed to investigate the association...

Background: Sacral masses can be removed using anterior, posterior, or combined approaches. Achieving total sacrectomy through a posterior-only approach results in a shorter procedure time, minimal tissue damage, and a reduced risk of complications. Objectives: In this study, we aimed to share our experience with performing total sacrectomy usin...

Background Cardiovascular diseases are the main cause of mortality in the world. This study aimed to estimate the incidence and identify the risk factors of these diseases. Methods This prospective cohort study was performed on 9442 individuals aged 40–70 years in Kharameh, a city in the South of Iran, in 2015–2022. The subjects were followed up f...

Background: Bariatric surgery is an appropriate treatment for obese patients with metabolic syndrome. Adipose tissue is an active endocrine tissue secreting leptin and adiponectin that affect body metabolism. Nowadays, a high incidence of metabolic syndrome with an increased risk of serious diseases has been detected in Shiraz. This study aimed to...

Background and Aim Prehypertension and hypertension are important risk factors for cardiovascular diseases. This study was carried out to evaluate the effect of prehypertension and hypertension on the development of cardiovascular diseases. Methods This prospective cohort study was performed on 9442 people aged 40−70 in Kharameh, southern Iran. In...

Background: Bowel obstruction is a disorder in the passage of bowel contents, the etiology of which varies depending on temporal and geographical conditions. This study investigated the etiology of bowel obstruction in a large number of patients at an adult surgery referral center in southern Iran. Methods: In this cross-sectional study, we reviewe...

Background Adaptive cognitive emotion regulation (CER) strategies toward eating play a very important role in obesity and according to schema therapy, patients with obesity learn that don't respond to their emotional stimuli by eating. Thus, this study aimed to evaluate the effectiveness of an online video-based group schema therapy in improvement...

Background and aims: Several studies have shown the association between obesity and sleep. Roux-en-Y gastric bypass (RYGB) surgery may improve sleep disturbances in patients with obesity by influencing a variety of factors. This study aims to evaluate the impact of bariatric surgery on sleep quality. Methods: Patients with severe obesity referre...

Background: Hypertension (HTN) is a significant public health concern globally. The study aims to estimate the incidence of HTN among adults aged 40 and above in southern Iran and identify the risk factors associated with it. Methods: The participants in the present prospective cohort study consisted of 7710 people aged 40–70 years. HTN is defined...

Background. Single anastomotic surgeries can increase the risk of reflux, marginal ulceration, and gastrointestinal complications. Braun anastomosis prevents bile reflux after gastric resection and gastrojejunal anastomosis surgeries. The present pilot study evaluated Braun’s efficacy in a single anastomosis sleeve ileal (SASI) bypass surgery. Meth...

Context: The uninterrupted dissemination and transmission of COVID-19 brought enormous jeopardy and public-health urgency during past three years. Some patients, who recovered from the infection, develop persistent symptoms and organ dysfunction for weeks or even months; conditions that are called long COVID. Among multiple COVID-related complicati...

Background Drug abuse is known as one of the most important health, medical, and social problems. Furthermore, this study was performed to evaluate the relationship between opium and lipid profiles. Methods This cross-sectional study was conducted on 10,663 individuals, aged 40 to 70, living in Kharameh (south of Iran). Demographic information, li...

Studies indicate an association between hyperuricemia (HUA) and metabolic syndrome risk factors. On the other hand, obesity is a major modifiable and independent risk factor for HUA and gout. However, evidence concerning the effects of bariatric surgery on serum uric acid levels is limited and not completely clarified. This retrospective study was...

Abstract Background Kidney stone is the major cause of morbidity, and its prevalence is increasing in the world. This study aimed to assess the prevalence and risk factors of kidney stone in the adult population of southern Iran based on the data of the Kharameh Cohort Study. Methods This cross-sectional study was conducted on 10,663 individuals ag...

Background and objective Tracheostomy in coronavirus disease 2019 (COVID-19) patients can be performed in cases of prolonged intubation or in patients with a known difficult airway. Tracheostomy is usually performed by two main approaches: open surgery or percutaneous endoscopic insertion. However, few studies have compared these two techniques in...

Background and Aim Multimorbidity is one of the problems and concerns of public health. The aim of this study was to estimate the prevalence and identify the risk factors associated with multimorbidity based on the data of the Kherameh cohort study. Methods This cross‐sectional study was performed on 10,663 individuals aged 40–70 years in the sout...

Introduction No standard of anatomical variables, including stoma size, limb length, pouch size, and volume, has been determined for laparoscopic Roux-en-Y gastric bypass yet. Herein, we evaluated the effect of two different techniques for creating the gastric pouch on short-term postoperative weight loss. Methods This retrospective cohort was con...

Obesity is an increasing problem that can lead to noncommunicable diseases. The role of dietary factors on one’s obesity is confirmed in many studies. One nutritional approach that can be used for assessment of the foods and diets is the Index of Nutritional Quality (INQ). Our study is aimed at exploring the association between INQ and obesity. Our...

Introduction: SARS-CoV-2 infection (COVID-19) pandemic may influence the weight outcomes of bariatric surgeries (BS). Here, we intended to compare the weight outcome of patients who underwent bariatric surgery before and during the pandemic time. Methods: In a retrospective, single-center study, the information of two groups of patients; first C...

Background: Conventional treatments may not be effective in some severe cases of fecal incontinence (FI). Objectives: In the present study, we evaluated the applicability of ventral pelvio-anal reconstruction (VPAR) as a modified operative technique for 17 patients with severe and refractory FI. Methods: We performed VPAR by placing a mesh in the p...

Background Sparse data are available regarding the efficacy and safety of single anastomosis sleeve ileal (SASI) bypass surgery, where most available studies utilized short-term follow-ups. Therefore, this study was conducted to evaluate the safety and outcomes of this procedure in three consecutive years after the surgery.Materials and methodsThis...

Purpose The present study aimed to compare two newly introduced procedures, single anastomosis sleeve jejunal (SASJ) with ileal (SASI) bypass in terms of weight loss, remission of obesity-associated medical problems, complications, and nutritional status. Materials and Methods This retrospective study was carried out with 162 patients who underwen...

Background: Anastomotic leakage is a significant complication after colorectal anastomosis. The aim of this study was to evaluate the risk factors and preventive measures for anastomotic leakage after rectal cancer surgery. Methods: A total of 171 patients who had undergone laparoscopic and open rectal cancer resection with a double stapling partic...

Background and Purpose: Oral health is a critical factor in the quality of life (QoL) of older adults in relation to their nutrition, mental health, and healthy social relationships. This study aimed to investigate oral problems and psychological status of older adults referred to a hospital and its relationship with cognition status, stress, anxie...

Objective: Gastrointestinal bleeding is one of the surgical emergencies that is routinely visited in emergency departments. Although most of these patients are managed with endoscopic modalities, some of them are managed with surgical interventions. Most of emergency surgical interventions are done via laparotomy. With evolution in minimal invasive...

Background: Previous studies have reported that gastrectomy and fundectomy can induce osteopenia. Body fat index is a new index of obesity that shows central obesity and other risks of obesity. Sleeve gastrectomy (SG) is a bariatric surgery and a new technique introduced as subsleeve, which only resected fundus of the stomach. In this study, it ha...

Following publication of the original article [1], the author name “Seyed Vahid Hosseini” was incorrectly written as “Seyed Vahid Hoseini”. The original article has been corrected. The online version of the original article can be found https://doi.org/10.1186/s12893-022-01591-2.

Abstract Background The prevalence of cardiovascular disease (CVD) is rapidly increasing in the world. The present study aimed to assess the prevalence and Predictors factors of CVD based on the data of Kherameh cohort study. Methods The present cross-sectional, analytical study was done based on the data of Kherameh cohort study, as a branch of th...

Background Colorectal cancer (CRC) is the second most common cancer in women and the third most common cancer in men worldwide, with an increasing trend in its incidence in Asian countries. In the present study, we aimed to describe the 13-year results of patients with CRC based on the Shiraz Colorectal Cancer Surgery (SCORCS) registry system in pa...

Background Rectal cancer accounts for one-third of all colorectal cancer (CRC) cases. Due to physiological and anatomical differences, some researchers consider rectal cancer as a separate organ malignancy during the recent decades. However, limited studies have been conducted in this regard in Iran. Therefore, the aim of this study is to determine...

A Correction to this paper has been published: https://doi.org/10.1007/s11695-021-05582-9

A correction to this paper has been published: https://doi.org/10.1007/s11695-021-05562-z

Introduction The main goal of bariatric surgery (BS) in patients with morbid obesity is reducing body mass and fat mass (FM). However, body mass loss is systematically accompanied by a decline in fat-free mass (FFM). We aimed to examine the time-course effect of BS on FFM and body FFM percentage (FFM%) in morbidly individuals with obesity by conduc...

Background and aims: Nonalcoholic fatty liver disease (NAFLD) is common in severely obese individuals undergoing bariatric surgery. Assessing the prevalence and severity of NAFLD seems crucial since it may affect the prevention or development of more severe forms of fatty liver. Methods: This cross-sectional study was conducted on 228 severely o...

Background: Oxidative stress contributes to the development of cardiovascular disease. Tools for evaluating the anti-inflammatory and antioxidative characteristics of an individual’s diet as a whole may be valuable for assessing the combined effects of dietary antioxidants on health. This population-based study aimed to investigate the association...

Purpose: Wounds with dead tissue, purulent wounds, and gangrene are good options for larval therapy. We aim to investigate the effect of larval therapy on diabetic wounds and compare it with traditional treatment. Methods: The sterile larvae were used in wound treatment and the infection rate, Erythrocyte Sedimentation Rate (ESR), and wound size...

Background and objectives Low back pain (LBP) is a common health condition in populations. Limited large-scale population-based studies evaluated the prevalence and predictors of LBP in developing countries. This study aimed to evaluate the prevalence and factors associated with LBP among the Iranian population. Methods We used baseline informatio...

PurposeLittle is known about the symptoms of coronavirus disease 2019 (COVID-19) on patients with morbid obesity following bariatric surgery (BS) in Iran. Thus, we sought to investigate the symptoms and effect of COVID-19 in patients with morbid obesity following, or candidates for, BS in Iran.Materials and Methods In this retrospective observation...

Aim: This study investigated the association between methylation status and expression levels of BTG2, PPP1CA, and PEG3 genes in colon cancer. Background: Aberrant DNA methylation is one of the most important epigenetic modifications in the development of cancer. Evidence indicates that hypermethylation of various tumor suppressor genes could be...

Background: Cystic echinococcosis (CE) is a life-threatening disease in many countries. Albendazole, as the drug of choice for medical treatment of CE, is accompanied by adverse effects and may be ineffective in 20%-40% of cases; hence, new and more effective compounds are urgently needed to optimize the management of the disease. This study was p...

Background: Emotions, attitudes, and behaviors toward eating play a very important role in obesity and according to a schema-based approach; patients with obesity learn some coping strategies since childhood to cope with the schemas. So, this study aims to evaluate the effectiveness of group schema therapy on the cognitive emotion regulation (CER)...

Statement of the problem: Oral health is one of the most important public health problems. The DMF index is used to assess oral health status. Purpose: This study was performed to evaluate oral health status based on DMF index in adults in Fars province. Materials and method: This cross-sectional study was performed on 8911 people aged 40 to 7...

Background: Colectomy is considered as a part of therapeutic armamentarium in ulcerative colitis. The availability of new biologic treatments might have affected the trend of using this modality. Methods: The hospital records of all tertiary centers in Shiraz, which are the main centers for the treatment of ulcerative colitis (UC) in southern Ir...

This systematic review and meta-analysis investigated the time-course effect of different type of bariatric surgeries (BS) up to 1 year post-surgery on fat mass (FM) and body fat percentage (BFP) in patients with morbid obesity. We searched PubMed, Scopus, EMBASE, ISI web of science, and Cochrane databases from October 2002 until May 2020 with no r...

Background: Rectal cancer is a malignant tumor of the digestive tract, and as it is a widespread condition, it demands comprehensive research. At the time of writing this study, coronavirus disease 2019 (COVID-19) affliction rates are rising rapidly in Iran. Hence, this study attempts to evaluate the country’s rectal cancer management during the pa...