Sevil AlbayrakErciyes Üniversitesi · Department of Biology
Sevil Albayrak
Ph.D.
About
53
Publications
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1,252
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Introduction
Phytochemistry, Natural Products, Essential oils & Aroma Chemicals, Ethnopharmacology, Ethnobotany, Food chemistry, Drug Discovery.
E mail: sevilalba@gmail.com
salbayrak@erciyes.edu.tr
Additional affiliations
January 2010 - December 2012
Publications
Publications (53)
In this research, the total phenolic and flavonoid amounts, phenolic compositions, in vitro antioxidant, antibacterial and antidiabetic properties of the methanol extracts obtained from Scabiosa L. ( Caprifoliaceae ) species distributed in the flora of Türkiye were investigated using chemometric methods. For this purpose, principal component (PCA)...
Abstract This study investigates the chemical compositions and biological activities of the methanol extracts of three endemic Teucrium species (T. ekimii, T. pestalozzae and T. semrae) collected from Turkey. Total phenolic and flavonoid contents were assessed spectrophotometrically. The total phenolic and flavonoid content in the T. ekimii methano...
Astragalus argaeus is an endemic plant species that is under critical risk of extinction. Here we investigated its population census, breeding system and reproductive success to determine the main factors affecting restricted distribution of this species. According to the results from pollination experiments, A. argaeus was autogamous but benefit f...
This study contains the synthesis of the 1-(2-methyl-1,4-benzodioxane)benzimidazole and 2-methyl-1,4-benzodioxane substituted benzimidazolium salts. The benzimidazolium salts were synthesized from the reaction of the 1-(2-methyl-1,4-benzodioxane)benzimidazole and various aryl chlorides. All compounds were characterized using 1H NMR, 13C NMR, FTIR s...
In this study evaluated the phenolic, flavonoid contents, antioxidant, antimicrobial and cytotoxic activities of Achillea coarctata extract. Also, chemical compositions of the extract and essential oil were analyzed by HPLC and GC–MS. The antioxidant activity of the extract was determined with phosphomolybdenum, DPPH (2,2-diphenyl-1-picrylhydrazyl...
Objective: In this study, biological property of Origanum minutiflorum O. Schwarz and P. H. Davis (Lamiaceae) was evaluated. Methods: The total phenolic and flavonoid amount were detected using Folin-Ciocalteu and aluminum chloride colorimetric assays. The antioxidant activity was assayed with phosphomolybdenum, 2,2- diphenyl-1- picrylhydrazyl radi...
Athyrium plants consist of more than 230 species that are largely distributed in the Sino-Himalayan region and the Western Pacific islands. Athyrium species are being used in traditional medicine worldwide to treat various ailments such as cough, rheumatic pain, scorpion stings, sores, burns and scalds, intestinal fever, pain, specifically breast p...
In the present study, some properties of the sorbets of rose, unripe grape, evil eye, linaria, engagement, and sirkecunbin were examined. Some physicochemical, bioactive, and sensory properties and the color parameters of the sorbets in their natural brix were determined. Additionally, the phenolic profiles of the sorbets were identified with LC‐MS...
Objective
The objective of the present study was to investigate the phenolic compositions, antioxidant, antimicrobial and cytotoxic activities of four
Methods
The total phenolic and flavonoid contents of methanol extracts obtained from four
Results
The extracts exerted moderate antioxidant and reducing activity with low phenolic contents. The mai...
Achillea L. (Asteraceae) is a traditional medicinal herb which contains different phenol and flavonoid compounds that are responsible for Achillea pharmacological effects. Turkey is one of the most important centers of diversity for the genus Achillea in the world. The aim of this research was the investigation of the cytotoxic activity of A. coarc...
Astragalus L. is the largest genus in the family Leguminosae with over 3000 species and is represented in Turkey by 445 species, of which 224 are endemic. Several Astragalus species have many biological properties such as hepatoprotective, immunostimulant, antiviral, anti-aging, antitumor, antioxidant, antimicrobial, antimalarial, antileshmanial, a...
Objective:
The present study aimed to compare the polyphenol content, total phenolic, total flavonoid, antioxidant and antimicrobial activity of the extracts obtained from Centaurea amaena Boiss. & Balansa and Centaurea aksoyi Hamzaoğlu & Budak.
Methods:
Both species were subjected to maceration, Soxhlet and ultrasonication extractions with meth...
Objectives
In vitro biological activities of methanolic extracts of five Turanecio species have been studied.
Materials and Methods
The phenolic compositions of the extracts were evaluated by the Folin- Ciocalteu assay and by HPLC analysis. Antioxidant activities were determined with two in vitro assays namely, DPPH (2,2-diphenyl-1-picrylhydrazyl)...
Five novel benzimidazolium salts were synthesized as N-heterocyclic carbene (NHC) precursors (1a-e). They were characterized by different techniques. The antimicrobial activities of these compounds were tested. The compounds showed moderate activity against three Gram (+) and seven Gram (bacteria ia in comparison to tetracycline, which was used as...
A series of new benzimidazolium salts (1a-g) were synthesized from the reaction of 1-(4-vinylbenzyl)benzimidazole with various alkyl halides. These salts were used to synthesize silver N-heterocyclic carbene (Ag-NHC) complexes (2a-f). The thirteen compounds were characterized by FT-IR, NMR ((1)H and (13)C) spectroscopic methods and an elemental ana...
C. aksoyi Türkiye florasında bulunan endemik bir bitki türüdür. Bu çalışmada C. aksoyi’nin metanollü ekstresinin antioksidan aktivitesi fosfomolibdenyum ve DPPH serbest radikal süpürücü aktivite olmak üzere iki farklı yöntemle araştırılmıştır. Fosfomolibdenyum yönteminde metanollü ekstrenin antioksidan aktivitesi 135.38 ± 0.1 mg askorbik asit g-1ek...
The present study was conducted to investigate total phenolic contents, antioxidant and antimicrobial activities of four Senecio L. (Asteraceae). The in vitro antioxidant activities of extracts were evaluated with different antioxidant testing systems. Their antioxidant activities were assessed by phosphomolybdenum reduction, DPPH and β-carotene bl...
The antioxidant activities of methanol (ME), ethanol (EE), water (WE) and ethyl acetate (EAE) extracts of four Inula helenium L. taxa (I. helenium ssp. orygalis (Boiss.) Grierson, I. helenium ssp. pseudohelenium Grierson, I. helenium ssp. turcarasemosa Grierson and I. helenium ssp. vanensis Grierson) were investigated. The phosphomolybdenum assay,...
Objective
The phenolic components and biological activity of nine Senecio species growing in Turkey were investigated. Methods
Senecio species were extracted with methanol. The content of total phenols was determined using Folin-Ciocalteu method, while individual phenolic acids and flavonoids were detected using HPLC analysis. Also, to determine th...
The extract obtained from Heracleum argaeum Boiss. & Bal. (Apiaceae) has been investigated for its total antioxidant capacity, inhibition of the bleaching of the β-carotene–linoleic acid emulsion and scavenging capacity on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. In addition to the antioxidant activity of this plant, the total phenolic and fla...
A series of unsymmetrically substituted N-heterocyclic carbene (NHC) precursors (1a, 1b, 1c, 1d, 1e) were synthesized from the reaction of N-phenylbenzimidazole with various alkyl halides. These compounds were used to synthesize NHC-silver(I) complexes (2a, 2b, 2c, 2d, 2e). The five new 1-phenyl-3-alkylbenzimidazolium salts (1a, 1b, 1c, 1d, 1e) and...
In this study, the methanolic extracts and lichens acids obtained from six Umbilicaria species were tested for their antimicrobial activity (against three Gram-positive bacteria, five Gram-negative bacteria and two yeasts species) and their antioxidant activity. Total phenolic content in the extracts was determined by the Folin–Ciocalteu assay. It...
The present study was conducted to evaluate the antioxidant and antimicrobial activities of methanol extracts of Anthemis fumariifolia and Anthemis cretica subsp. argaea, which are commonly used in Turkish folk medicine. The total phenolic and total flavonoid contents in the extracts were determined. The antioxidant activities of the extracts were...
The methanolic extracts, infusions, decoctions and hydrosols of six plants were investigated for their total phenolic contents, antioxidant and antimicrobial activities: Mentha piperita (Peppermint), Thymus vulgaris (thyme), Melissa officinalis (lemon balm), Ocimum basilicum (basil), Rosmarinus officinalis (rosemary) and Salvia officinalis (sage) (...
Thymus revolutus Celak (Lamiaceae) is an endemic species in Turkey. Cyclotrichium origanifolium (Labill.) Manden & Scheng (Lamiaceae) has been widely used as a flavoring agent in soups and salads, and herbal tea in Turkey. The essential oil (EO) components, antioxidant and antimicrobial activities of the extracts and EOs of T. revolutus and C. orig...
The present study was conducted to evaluate the phenolic contents, antioxidant and antimicrobial activities of methanol extract (ME), ethanol extract, water extract (WE) and essential oil of Thymus cappadocicus Boiss. The essential oil composition of a hydrodistilled essential oil of T. cappadocicus was analyzed by a gas chromatography/mass spectro...
The reaction of 1H-pyrazole-3-carboxylic acid chloride (1) with various hydrazine derivatives 2a-c yielded the corresponding N,N-disubstituted 4-benzoyl-1,5-diphenyl-1H-pyrazole-3-carbohydrazides 3a-c. These products underwent Friedel-Crafts acylations with arenes to afford compounds 4a-c. Treatment of 1 with aromatic diamines produced 1H-pyrazole-...
The methanolic extracts of 16 Helichrysum species were investigated for their in vitro antioxidant, radical scavenging and antimicrobial activities. All the extracts showed strong antioxidant and radical scavenging activity. The highest total antioxidant capacity as ascorbic acid equivalents (AAE) of 194.64 mg/g dry extract was obtained for Helichr...
The 1H-pyrazole-3-carboxylic acid 1 was converted via reactions of its acid chloride 3 with various asymmetrical disubstituted urea and alcohol derivatives into the corresponding novel 4-benzoyl-N-(N′,N′-dialkylcarbamyl)-1-(4-methoxyphenyl)-5-phenyl-1H-pyrazole-3-carboxamide 4a,b and alkyl 4-benzoyl-1-(4-methoxyphenyl)-5-phenyl-1H-pyrazole-3-carbox...
The in vitro antioxidant and antimicrobial activities of the essential oil and methanolic extract of Achillea sieheana Staf. (Asteraceae) were investigated in this study. The chemical composition of the essential oil isolated by hydro-distillation from the aerial parts of A. sieheana was analyzed by GC-MS. Camphor (43.36%), Artemisia ketone (25.95%...
To evaluate total phenolic, antioxidant and antimicrobial activities of methanolic extracts of the Wiedemannia multifida (W. multifida) and Wiedemannnia orientalis (W. orientalis).
Phosmomolybdenum assay, DPPH radical scavenging activity and β-carotene-linoleate bleaching were used to evaluate the antioxidant capacity.
The total phenolics were foun...
Tıbbi ve aromatik bitkiler eski çağlardan beri insanlar tarafından doğadan toplanmakta ve ilaç yapımında, gıdaları koruyucu,
çeşni verici ve iştah açısı olarak kullanılmaktadır. Söz konusu bitkilerden biriside kişniştir. Maydanozgiller familyasından olan
kişniş, halk arasında aşotu, kinzi, kişnit, yumurcak, kara kimyon ve kuzbere gibi diğer isimler...
Methanol (MeOH) extracts, infusions and decoctions of eight plants were investigated for their antioxidant activity using phosphomolybdenum and 2,2‐diphenyl‐1‐picrylhydrazyl assays: Cassia angustifolia (Senna tea), Foeniculum vulgare (fennel), Pimpinella anisum (anise), Laurus nobilis (laurel), Tilia vulgaris (linden tea), Urtica dioica (nettle), P...
In this study, the effect of gamma irradiation on the total phenolic content and antioxidant activity of Satureja hortensis, Thymus vulgaris, and Thymbra spicata was evaluated. Plants irradiated in a 60Co irradiator to 0, 1.2, 3.0, and 5.1 kGy at 25°C. Control and irradiated samples were extracted with methanol. The antioxidant activity of methanol...
The antioxidant activity of the methanolic extracts of 4 plants from genus Helichrysum Mill. (Asteraceae) [H. arenarium (L.)Moench subsp. erzincanicum Davis & Kupicha, H. arenarium (L.)Moench subsp. rubicundum (C.Koch.) Davis & Kupicha, H. armenium DC. subsp. araxinum (Kirp.) Takht., and H. plicatum DC. subsp. pseudoplicatum (Nab.) Davis & Kupicha]...
Helichrysum Mill., (Asteraceae) species have been used in folk medicine for thousands of years in the world. The In vitro cytotoxic effects in human lymphocytes of 6 Helichrysum taxa used in Turkey folk medicine were investigated. Blood samples were obtained from healthy donors, non-smoking volunteers, which were incubated and exposed to increasing...
In the present study, the methanolic and water extracts of Paronychia mughlaei Chaudhri (Caryophyllaceae) were examined for their total phenolic content, potential antioxidant and antimicrobial activities. The total phenolic contents of the extracts were measured by Folin-Ciocalteu method. Antioxidant activity of both extracts were analysed using 2...
In this study, total contents of phenolic, flavanol and flavonol, antioxidant activities and antimicrobial activities of the Turkish endemic Salvia pisidica Boiss. & Heldr. ex Bentham (Lamiaceae) extract and essential oil were assessed in vitro. Total phenolic, flavanol and flavonol contents in the extract were 54.57 mg gallic acid equivalents (GAE...
Helichrysum Mill., belonging to the family Asteraceae, is commonly known as "everlasting". Helichrysum species have been used as herbal tea for centuries in Turkey against gallbladder disorders because of their bile regulatory and diuretic properties. However, there are few reports in the literature regarding the genotoxic effects of these plants....
The in vitro genotoxic potential of methanol extract of Senecio trapezuntinus in human lymphocytes was investigated. Blood samples were obtained from six healthy donors, non-smoking volunteers, who were incubated and exposed to increasing concentrations of Senecio trapezuntinus (0.002, 0.01, 0.05 and 0.1 mg/mL). Senecio trapezuntinus induced micron...
Helichrysum Mill. (Asteraceae) species have been used in folk medicine for thousands of years in the world. The in vitro cytogenetic
effects in human lymphocytes of nine Helichrysum taxa used in Turkey folk medicine were investigated. Blood samples were obtained from healthy donors, non-smoking volunteers,
which were incubated and exposed to increa...
In this study, the antioxidant activity of ethanol extract of Salvia halophila Hedge (Lamiaceae) was evaluated by 2 antioxidant assays, including phosphomolybdenum reduction and free radical scavenging activity. The ethanol extract showed free radical scavenging activity with IC50 of 67.73 μg/mL in 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The an...
This study focused on determining the minimal effective gamma radiation dose that prevents commodity damage caused by the Indian meal moth Plodia interpunctella (Hübner). The study was also designed to assess the effect of releasing either partially sterilized males alone or both partially sterilized males and females on the reproductive potential...
In this study, it was investigated the antioxidant, antiradical and antimicrobial activities of methanolic extracts from three Helichrysum species [H. pamphylicum Davis & Kupicha, H. sanguineum (L.) Kostel, H. chasmolycicum P.H. Davis (Asteraceae)]. The total phenolic contents of methanolic extracts ranged from 71.51 to 119.85 mg gallic acid/g dry...
It has long been known that herbs and their extracts have an antimicrobial activity. Sideritis ozturkii Aytac & Aksoy and Sideritis caesarea Duman, Aytaç et Baser endemic plant species for Turkey have been traditionally used as medicinal tea and spice in different regions of Turkey especially the Mediterranean and the middle part of Anatolia. In th...
Total phenolic contents, antioxidant and antimicrobial activities of methanol extracts of six Senecio species growing in the Black Sea region of Turkey (S. pandurifolius, S. trapezuntinus, S. integrifolius subsp. aucheri, S. hypochionaeus var. argaeus, S. hypochionaeus var. ilkasiensis and S. orentii) are investigated. The total phenolic content is...
The effects of gamma radiation on the fecundity, fertility, longevity, development and level of inherited sterility in the Mediterranean flour moth Ephestia kuehniella were determined. Newly emerged virgin Mediterranean flour moth adults were irradiated with 100, 200, 400 and 600Gy in a 60Co irradiator with a source strength of ca. 3811Ci and a dos...