Serkan Kuccukturk

Serkan Kuccukturk
Karamanoglu Mehmetbey Üniversitesi · Department of Medical Biology

PhD, Medical Biologist, Sleep Technologist

About

37
Publications
8,535
Reads
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145
Citations
Citations since 2017
22 Research Items
141 Citations
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20172018201920202021202220230102030
20172018201920202021202220230102030
Additional affiliations
February 2021 - present
Karamanoglu Mehmetbey Üniversitesi
Position
  • Professor (Assistant)
July 2011 - August 2012
The Institute of Health Sciences
Position
  • Researcher
September 2009 - March 2017
Necmettin Erbakan Üniversitesi
Position
  • PhD
Education
October 2009 - March 2017
Necmettin Erbakan Üniversitesi, Meram Faculty of Medicine
Field of study
  • Medical Biology, Molecular Genetics
September 2007
Medical Faculty of Selcuk University
Field of study
  • Sleep Technologist
September 2006 - September 2009
Selcuk University
Field of study
  • Medical Biology, Molecular Genetics

Publications

Publications (37)
Conference Paper
Full-text available
Gliomas, the most common type of brain tumors, are the most aggressive and invasive primary malignant brain tumors, with a high morbidity rate and a five-year survival rate of 20-30%. This poor prognosis is largely due to therapeutic resistance and recurrence of the tumor after resection. Among glial tumors, ependymoma tumors arise from ependymal c...
Article
Full-text available
Amaç: Corona Virüs 2019 Hastalığı (COVID-19)’nda şu ana kadar spesifik antiviral ajan olmamasına rağmen tedavi için konvelesan plazma (CP) tedavisi tedavi için kullanılmıştır. Ancak CP tedavisinin prognoz ve mortalite üzerindeki etkinliği halen tartışma konusudur. Bu çalışmada COVID-19 hastalığında CP tedavisinin etkinliğine ilişkin deneyimlerimizi...
Conference Paper
Full-text available
Anticancer agent research on head and neck tumors and tumor microenvironment related tissues has gained importance in recent years. Growth suppressive evidence on cancer cell lines regarding the anticancer therapeutic potential of diarylpentanoids is available in the literature. The anticancer activity of GO-Y030, one of the diarylpentanoids, on br...
Article
Full-text available
Introduction and aim. Intense taekwondo (TKD) training, it is important to know the exercise-induced hematological and in-flammatory conditions and to develop conditions suitable for physiological needs. The aim of study is to investigate the effects of TKD-specific training containing a high-intensity interval training (HIIT) component hematologic...
Conference Paper
Full-text available
Özet: 2019 yılının sonunda Çin’in Wuhan şehrinde SARS-CoV-2 olarak isimlendirilen yeni tip bir betakoronavirüsün sebep olduğu “Korona Virüs 2019 Hastalığı (COVİD-19)” yeni bir pandemi olarak ortaya çıkmıştır. COVID-19’a bağlı immünolojik yanıtlarda T hücre ait sitokinler ciddi rol oynamaktadır. Sitokin oluşumunda ilgili genin transkripsiyon faktörl...
Conference Paper
Full-text available
Özet: CD19 eksikliği tekrarlayan enfeksiyonların yanı sıra otoimmün hastalıklara yatkınlıkla seyreden bir primer immün yetmezlik grubudur. Ancak otoimmüniteye yatkınlık mekanizması halen açık değildir. Regülatör T hücreler (Treg) diğer T hücre (Th1, Th2, Th17) yanıtlarını kontrol altında tutarak otoimmün hastalıkların önlenmesinde majör rol oynayan...
Article
Full-text available
Aim: The instant study’s aim is to investigate the effect that BUN and creatinine values have on a prognosis in geriatric patients that are diagnosed with pulmonary embolism. Material and methods: Our study was planned as a retrospective data review and included patients over the age of 65 with a diagnosis of pulmonary embolism who were admitt...
Article
Full-text available
Introduction: Cervical cancer is the fourth most common cancer in worldwide and the leading cause of death among gynecological cancers. Neferine is a bisbenzylisoquinoline alkaloid isolated from the seed embryo of Nelumbo Nucifera. Studies have shown that Neferine has anticancer effects on a variety of human cancer cells. Neferine can induce apopto...
Article
Sleeping positions have a significant impact on exposure of apnea patients to sleep apnea. In this study, the sleeping position of the patient was read with the STM microcontroller by using the body position sensor (SleepSense 1/8" Plug DC Body Position Sensor Kit) produced by the sleep sense company. This sensor produces results with analog signal...
Article
Full-text available
Introduction and aim. Mutation(s) in the gene encoding the CD19 molecule affect CD19 protein expression and primary immunodeficiency (PID) occurs. The PCR-RFLP method, which is faster and cheaper than other mutation detection methods, is rarely used in the diagnosis of PID. The study aimed to genetically identify CD19 deficiency, which is a PID, us...
Article
Background and aim: A high D-dimer level may indicate the risk of coagulopathy and mortality in COVID-19 patients. Thromboelastography (TEG) is a test that evaluates clot formation and fibrinolysis in real-time, unlike routine coagulation tests. The study aimed to investigate the coagulation process with TEG in patients diagnosed with COVID-19. Mat...
Article
Full-text available
Introduction: Coronavirus 2019 disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread to more than 200 countries worldwide. We aimed to present acute pancreatitis (AP) cases caused by SARS-CoV-2 viral infection. Methods: The study was conducted retrospectively between April 2020 and June 2020 i...
Article
Background and Purpose: This study aimed to investigate the effect of intermittent diet and/or physical therapy in patients with chronic low back pain. Materials and Methods: Sixty sedentary volunteers with chronic low back pain participated in the study. Body weight and body mass index (BMI) were measured. Pain severity was assessed using Visual A...
Article
Full-text available
The diagnosis of obstructive sleep apnea hypopnea syndrome (OSASH) and making decision of treatment necessity with positive airway pressure (PAP) therapy are time consuming and costly processes. There were different approaches in literature to accomplish these processes successfully and as soon as possible by using physiological signals with select...
Article
Full-text available
Sleep staging is a significant process to diagnose sleep disorders. Like other stages, several parameters are required for the determination of N-REM2 stage. Sleep spindles (SSs) are among them. In this study, a methodology was presented to automatically determine starting and ending positions of SSs. To accomplish this, short-time Fourier transfor...
Article
Full-text available
Sleep staging process is applied to diagnose sleep-related disorders by sleep experts through analyzing sleep signals such as electroencephalogram (EEG), electrooculogram and electromyogram of subjects and determining the stages in 30-s-length time parts of sleep named as epochs. Subjects enter several stages during the sleep, and N-REM2 is one of...
Article
Full-text available
Interference between EEG and EOG signals has been studied heavily in clinical EEG signal processing applications. But, in automatic sleep stage classification studies these effects are generally ignored. Thus, the objective of this study was to eliminate EOG artifacts from the EEG signals and to see the effects of this process. We proposed a new sc...
Article
Methylmethane sulfonate (MMS) is an alkylating agent that may react with DNA and damage it. We investigated histological changes and apoptosis caused by MMS and the effects of curcumin on MMS treated mouse kidneys. Twenty-four mice were divided into four equal groups: controls injected with saline, a group injected with 40 mg/kg MMS, a group inject...

Questions

Questions (2)
Question
Sleep is essential for surviving in all higher animals. Humans sleep approximately a third of their lifetime, and too little or too much sleep was often found to be associated with metabolic or psychiatric disorders. Sleep duration can be influenced by photoperiod and sleep time, and strongly depends on age and gender. However, a genetic component is also strongly suspected since twin studies indicate as much as 40% heritability in individual sleep duration.
A genome-wide study conducted in more than 4000 individuals from seven European populations recently published in Molecular Psychiatry allowed to identify a variant in the ABCC9 gene which would explain sleep duration variations of about 5% (i.e. 24 minutes) between individuals.
The ABCC9 gene encodes a subunit of a potassium channel and is very conserved throughout evolution. It was previously known to be associated with energy metabolism and response to stress, and involved in some cardiomyopathies and cardiac rhythm disturbances. Interestingly, flies devoid of this gene have dramatically reduced night-sleep, due to a delay of its onset by 3 hours. This demonstrates that this gene is relevant for the modulation of sleep in distant species, and could provide clues to understand the complex relationships between sleep and metabolic disorders.
Question
I have attached the data of my results but I'm not sure how to proceed, could you help me?

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