Sergio Manzetti

Sergio Manzetti
Uppsala University | UU · Department of Cell and Molecular Biology

Doctor of Molecular Biotechnology
Research student in Mathematics

About

120
Publications
53,186
Reads
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2,148
Citations
Additional affiliations
October 2020 - present
University of Gävle
Position
  • Doctorate
Description
  • I am currently studying various mathematical subjects to complete a Bachelors Degree in Mathematics.
February 2003 - February 2004
University of Oslo
Position
  • Researcher
Description
  • Doctoral Scientist in molecular biology.
August 2001 - December 2001
Queensland University of Technology
Position
  • Laboratory Assistant
Description
  • Laboratory assistant Biochemistry
Education
November 2020 - June 2023
University of Gävle
Field of study
  • Mathematical analysis of Bessel functions in scattering models
January 2015 - June 2022
Uppsala University
Field of study
  • Computational Chemistry and Biology studies on nanomaterials and ecotoxins
January 2001 - January 2003
Queensland University of Technology
Field of study
  • Computational Biology and Biotechnology study of Tissue Kallikreins

Publications

Publications (120)
Article
Electric and hybrid vehicles are associated with green technologies and a reduction in greenhouse emissions due to their low emissions of greenhouse gases and fuel-economic benefits over gasoline and diesel vehicles. Recent analyses show nevertheless that electric vehicles contribute to the increase in greenhouse emissions through their excessive n...
Article
Full-text available
Solar cell technologies are highly dependent on silicon materials and novel nanoclusters with optimal electronic properties. Based on a recent study on ultrastable silicon nanoclusters, an analysis of the effects of modifications of those nanocrystals by carboxylation, amidation, hydroxylation and halogenation has been performed using quantum mecha...
Preprint
Full-text available
Anomalous waves and rogue events are closely associated with irregularities and unexpected events occurring at various levels of physics, such as in optics, in oceans and in the atmosphere. Mathematical modeling of rogue waves is a highly active field of research, which has evolved over the last few decades into a specialized part of mathematical p...
Technical Report
Full-text available
Theory on non-self-adjoint operators (NSA) and non-self adjoint algebra has been developed over the last century, particularly since the extensive work by von Neumann. Non-self-adjoint operators describe problems in physics and prove as examples in the Schroedinger equation, the Gross-Pitaevskii model for Bose-Einstein condensates and other equatio...
Technical Report
Full-text available
Rogue waves are anomalous phenomena occurring over large sea bodies, where they are said appear out of nowhere and disappear without a trace. Simulations of rogue waves have been carried over the last 40 years, with several models published. In this paper we investigate the formation of rogue waves by two models: I. the Navier-Stokes equation where...
Presentation
Full-text available
The gut microbiome comprises several hundreds of bacterial species that partake in the production of vitamins and organic compounds in the gut, playing a vital role for digestion, metabolism and absorption of nutrients. The sensitivity of these vital bacterial species to nutrients and environmental stimuli has been studied over decades and designat...
Thesis
Full-text available
Human society has progressed by polluting ecosystems since the early industrial revolution. Thus, large amounts of harmful chemical compounds have been dispersed in soils, seas, groundwaters and wildlife habitats, leading to a persistent toxicological load on the environment. Pollution is a threat to biodiversity, to the health of ecosystems, and t...
Technical Report
Full-text available
Superfluid Helium4 has been known since the late 1960's to condense on the outside of its container when it reaches temperatures close to the absolute zero. Several models have been developed over the years to describe the dynamics of Helium, both thermodynamiacal models as well as non-equlibrium models. Here we introduce a new model of the behavio...
Technical Report
Full-text available
Wave-equation for modelling the cosmic web.
Technical Report
Full-text available
The term "quantum fractals" is here related to a symmetric sewing-pattern resulting for quantized wave-solutions for quasiparticles in a quantum void, subjected to an exponential decay of the vibrational component while maintaining a constant momentum. The phenomenon is modelled by a quantum diffusion equation which has similarities to the NLSE and...
Technical Report
Full-text available
Planetary magnetohydrodynamics is a central part of planetary sciences, where the magnetic field of the planet is studied in interaction with the Sun, solar storms and lunar cycles. In this paper, we study numerically the effects on the dynamics of electromagnetic vortices in the Northern hemisphere by the displacement of the magnetic North pole. U...
Presentation
Full-text available
ZOOM Address : David van der Spoel is inviting you to a scheduled Zoom meeting. Topic: Thesis defense Sergio Manzetti Time: Dec 4, 2020 01:00 PM Stockholm Join Zoom Meeting https://uu-se.zoom.us/j/66231601469 Meeting ID: 662 3160 1469 One tap mobile +46844682488,,66231601469# Sweden Dial by your location +46 8 4468 2488 Sweden Meeti...
Article
Quantum mechanical states are normally described by the Schrödinger equation, which generates real eigenvalues and quantizable solutions which form a basis for the estimation of quantum mechanical observables, such as momentum and kinetic energy. Studying transition in the realm of quantum physics and continuum physics is however more difficult and...
Presentation
Full-text available
Non-self adjoint operators describe problems in physics and computational sciences which lack symmetry and unitarity, and which display non-trivial solutions on an unbounded interval in Hilbert or Banach space. Non-self adjoint operators describe for instance problems in quantum mechanics and quantum theory, where the resolvent norm is approximated...
Technical Report
Full-text available
Environmental pollution and contamination is a continuous challenge that industrialized and developing countries are facing, affecting entire ecosystems, threatening biodiversity, reducing health and life quality of humans and contributing to the extinction of endangered species. The oceans and seas are the most vulnerable ecosystems to anthropogen...
Article
Thousands of anthropogenic chemicals are released into the environment each year, posing potential hazards to human and environmental health. Toxic chemicals may cause a variety of adverse health effects, triggering immediate symptoms or delayed effects over longer periods of time. It is thus crucial to develop methods that can rapidly screen and p...
Data
Spectrum of the attenuation operator for non-relativistic waves. Generated with EigTool.
Data
Spectrum of the attenuation operator for non-relativistic waves. Generated with EigTool.
Technical Report
Full-text available
A dropleton, or quantum droplet made of bosonic particles interacting via the long range dipole-dipole interaction is a collective state found in rare-earth metal gases. The properties of dropleton are particularly interesting, as droplets composed of a higher number of atoms with large enough magnetic moment may assume a supersymmetric ground stat...
Technical Report
Full-text available
Superconductors are principal components used in resonance imaging (MRI) and nuclear magnetic resonance (NMR) machines, tokamaks reactors, in particle accelerators and in other components in advanced technologies. Electromagnetic vorticity plays a significant role in superconductivity, as it allows for the generation of holes which permit electrons...
Technical Report
Full-text available
Simulations of galactic vorticity require the development of complex systems of equations to generate models that account for the gravity, mass, kinetic, and electromagnetic effects which govern cluster behaviour. In this study, a relationship is outlined through a series of steps, between the Einstein equations, the Ricci equations and the gravita...
Preprint
Thousands of anthropogenic chemicals are released into the environment each year, posing potential hazards to human and environmental health. Toxic chemicals may cause a variety of adverse health effects, triggering immediate symptoms or delayed effects over longer periods of time. It is thus crucial to develop methods that can rapidly screen and p...
Technical Report
Full-text available
Fundamental physical phenomena, such as gravity, electromagnetism and light have been studied over the last centuries for their properties, mechanics and for their relationships to one-another. Bernoulli proposed in 1736 a vortex-sponge theory to describe light in mechanical terms which was later postulated by using Maxwell's vortex equations. In t...
Article
Vortices and quasiparticles have been studied for 2D systems over the last decades in relation to the development of technologies in quantum electromagnetics, optics, and quantum computation. Deriving new equations for quasiparticles in quantum systems is therefore a critical part in quantum physics. Recently, a supersymmetric wave equation has bee...
Technical Report
Violin, violas, cellos and double basses have evolved over 4 centuries from the family of viols, a baroque/renaissance instrument from the 14th century. The acoustics is dependent on several factors: the quality and aging of the wood, the varnish, the shape and curvature of the surface and finally the f-holes. The f-holes have evolved from pairs of...
Data
Presentation of a novel baroque viola, well suited for gut or metal strings.
Presentation
Full-text available
Chart of fish species in the Sognefjord
Technical Report
Full-text available
Planetary atmospheric dynamics is a critical part of astrophysics, which aids in understanding the fluctuations in the atmosphere on other planets as well as planet Earth. Saturn has been known to display a peculiar behaviour on its North Pole, forming a hexagonal geometry in the atmosphere, driven by high-speed winds. Several models have been publ...
Article
Full-text available
The partitioning of compounds between aqueous and other phases is important for predicting toxicity. Although thousands of octanol–water partition coefficients have been measured, these represent only a small fraction of the anthropogenic compounds present in the environment. The octanol phase is often taken to be a mimic of the inner parts of phos...
Article
Vortices and quasiparticles in 2D systems are studied for the last decades in relation to the development of technologies in quantum electromagnetics, optics, and quantum computation. Hamiltonians are a fundamental part for studying quasiparticles and vortices, and provide models to calculate the eigenvalues and eigenfunctions that describe a real...
Technical Report
Full-text available
Macrophysical phenomena, such as turbulence, vorticity are normally modelled using fluid-mechanical differential equations and geodesics systems. Other methods may also be of importance to the meteorology community, such as quantum physical operators. In this study we use a novel Hamiltonian and study the vortex formation in the atmosphere of plane...
Technical Report
Full-text available
Vortexes in superfluids are a critical part of quantum optics, quantum dynamics studies and quantum physics in general. The behavior of vortexes is modeled by models such as the Ginzburg-Landau formula, and other systems, where symmetry-breaking is an inevitable event upon vortex formation. In this paper, we present and study a supersymmetric Hamil...
Article
Carbon nanotubes (CNTs) are a central part of advanced nanomaterials and are used in state-of-the-art technologies, based on their high tensile strength, excellent thermal transfer properties, low-band gaps and optimal chemical and physical stability. Carbon nanotubes are also intriguing given their unique π-electron-rich structures, which opens a...
Method
Full-text available
Removal of perfluorinated compounds from polluted waters.
Technical Report
Full-text available
Bose-einstein condensates have received wide attention in the last decades given their unique properties. In this study, we apply supersymmetry rules on an existing Hamiltonian and derive a new model which represents an inverse scattering problem with similarities to the circuit and the harmonic oscillator equations. The new Hamiltonian is analysed...
Technical Report
Full-text available
Vortexes in three dimensional systems are an emerging topic of study in the realm of quantum physics, particle physics and magnetism. In this study we describe a new Hamiltonian, and solve it numerically for the description of vortices in a spherical model subjected to an electromagnetic field. The numerical analysis shows also that supersymmetric...
Article
PFASs are a class of compounds that include perfluoroalkyl and polyfluoroalkyl substances, some of the most persistent pollutants still allowed - or only partially restricted - in several product fabrications and industrial applications worldwide. PFASs have been shown to interact with blood proteins and are suspected of causing a number of patholo...
Article
Full-text available
Quantum mechanical models for particles are strictly dependent on the Schrödinger equation, where the solutions and the Hermitian polynomials form a mathematical foundation to derive expectation values for observables. As for all quantum systems, the solutions are derived in discrete energy levels, and yield probability density, the kinetic energy...
Article
The bonding mechanisms between DEHP, PFOS, butylparaben and benzo[a]pyrene with the DNA were recently published [1] and showed intriguing mechanisms of complex formation between these priority pollutants and the gene core fragment of the p53 suppressor which were analyzed at the electronic level. The study supplied also important bonding data, incl...
Article
Anomalous waves and rogue events are closely associated with irregularities and unexpected events occurring at various levels of physics, such as in optics, in oceans and in the atmosphere. Mathematical modeling of rogue waves is a highly active field of research, which has evolved over the last few decades into a specialized part of mathematical p...
Preprint
Anomalous waves and rogue events are closely associated with irregularities and unexpected events occurring at various levels of physics, such as in optics, in oceans and in the atmosphere. Mathematical modeling of rogue waves is a highly actual field of research, which has evolved over the last decades into a specialized part of mathematical physi...
Data
Deck-height: 22 m. Possible wave-height 40-45 meter.
Article
Anomalous waves and rogue events are closely associated with irregularities and unexpected events occurring at various levels of physics, such as in optics, in oceans and in the atmosphere. Mathematical modeling of rogue waves is a highly actual field of research, which has evolved over the last decades into a specialized part of mathematical physi...
Poster
Full-text available
The search for spin-polarized metal clusters, energetic crystals and conductive materials is a paramount part of Nanotechnology. Adapting quantum chemistry and quantum mechanics methods to study and endeavor the electronic and lattice properties of groups of atoms in nanoclusters is a central approach, which aids in revealing crucial electronic pro...
Article
Full-text available
Streptococcus pneumoniae is the world’s foremost bacterial pathogen. Virulence in the host is dependent on manganese acquisition via the PsaBCA permease. Crystallographic studies of its solute-binding protein component, PsaA, have previously shown that the nature of the metal ion bound by the protein modulates the conformational changes associated...
Article
Full-text available
Quantum information processing is a critical part of the development of future computers, quantum computers, and quantum algorithms, where elementary particles such as photons and electrons can be applied in optomagnetic or optoelectronic devices. The computational physics behind these emerging approaches is also experiencing dramatic developments....
Preprint
Full-text available
Anomalous waves and rogue events are closely associated with irregularities and unexpected events occurring at various levels of physics, such as in optics, in oceans and in the atmosphere. Mathematical modeling of rogue waves is a highly actual field of research, which has evolved over the last four decades into a specialized part of mathematical...
Data
Table of contents for the book: "Quantum Chemical Toxicology: Theory, Methods and Applications on Nanoparticles and Molecular Carcinogens" by Sergio Manzetti
Article
Full-text available
Cooling of beverages is of large interest. Here a theoretical idea of how microwave ovens can be used for cooling beverages is presented. The proposed theoretical idea based on heat transfer features a microwave safe (isoprene rubber) torus shaped rubber ring (MWSR) holding a liquid (L) at room temperature. Fullerenol dissolved in acetone (L) insid...
Article
Parabens, phthalates, and perfluorinated compounds are pollutant compounds used in cosmetics, plastics, and fire-fighting foams. All three compounds have been studied over several years for toxicity mechanism; however, a clear view of their ability to bind to DNA has not been supplied empirically. In this work, a simulation study is done to reveal...
Article
In light of the importance of developing novel corrosion inhibitors, a series of quantum chemical calculations were carried out to evaluate 15N chemical shielding CS tensors as well as aromaticity indexes including NICS, HOMA, FLU, and PDI of three pyrazine derivatives, 2-methylpyrazine (MP), 2-aminopyrazine (AP) and 2-amino-5-bromopyrazine (ABP)....
Article
Nanomaterials composed of metals and metal alloys are the most valuable components in emerging micro- and nanoelectronic devices and innovations to date. The composition of these nanomaterials, their quantum chemical and physical properties and the methods of production are critical to be summarized, so that a complete state of the art of the prese...
Article
Advanced materials and surfaces are key components in nanotechnology and are applied by their magnetizable and spintronic properties, high-frequency scattering, and properties attributing to nanoelectronics and nanomagnetic components. Earth oxides are a group of materials with catalytic effects in nanocrystalline forms, and strong magnetic field e...
Article
A number of cases around the world have been reported where animals were found dead or dying with symptoms resembling a Thiamine (vitamin B) deficiency and for some of these a link to pollutants has been suggested. Here we investigate whether biomolecules involved in Thiamin binding and transport could be blocked by a range of different pollutants....
Article
Full-text available
Rhenium is a unique metal in the 5d-series of transition metals having the highest boiling point in the periodic table. It is also known to exist in poly-coordinated states with other rhenium atoms. Based on the existence of strikingly unusual states of elements in astrophysical bodies of nebulae, interstellar debris, exoplanets and other part of t...
Article
New water purification technologies are being developed as the world’s water sources are increasingly being polluted and experience a dramatic consumption with the increasing world population. In this context, the emerging era of nanotechnology has introduced a series of innovations and materials with promising potential as sorptive materials for w...
Conference Paper
Advanced materials and surfaces are key components in nanotechnology and are applied given their magnetizable and spintronic properties, high-frequency scattering, and other features attributed to nanoelectronics and nanomagnetic functionalities. Earth oxides are a group of materials with catalytic effects in nanocrystalline formats, and electronic...
Conference Paper
Full-text available
As a summary of work in the project " Influence of bioethanol fuels treatment for operational performance, ecological properties and GHG emissions of spark ignition engines (Biotreth) " , evolving around the effects from bioethanol blending, this paper summarizes the findings from the 3-year long project. These are 1) attributional life cycle asses...
Chapter
Full-text available
As a summary of work in the project " Influence of bioethanol fuels treatment for operational performance, ecological properties and GHG emissions of spark ignition engines (Biotreth) " , evolving around the effects from bioethanol blending, this paper summarizes the findings from the 3-year long project. These are 1) attributional life cycle asses...
Article
Full-text available
Correction for ‘Intriguing properties of unusual silicon nanocrystals’ by Sergio Manzetti et al., RSC Adv., 2015, 5, 78192–78208.
Article
Sludge deposition in the environment is carried out in several countries. It encompasses the dispersion of treated or untreated sludge in forests, marsh lands, open waters as well as estuarine systems resulting in the gradual accumulation of toxins and persistent organic compounds in the environment. Studies on the life cycle of compounds from slud...
Article
The quantum chemical calculations at the DFT/B3LYP level of theory were carried out on seven quinoxaline compounds, which have been synthesized as anti-Mycobacterium tuberculosis agents. Three conformers were optimized for each compound and the lowest energy structure was found and used in further calculations. The electronic properties including E...
Poster
Full-text available
Bioethanol has been increasingly applied as a renewable energy component in combination with gasoline for the reduction of emissions and to reduce the release of climate gases in the atmosphere. Blending of bioethanol and gasoline has however not been studied from a toxicological perspective, and our recent studies show that it can contribute to in...
Article
Bionanosensors and nanosensors have been devised in recent years with the use of various materials including carbon-based nanomaterials, for applications in diagnostics, environmental science and microelectronics. Carbon-based materials are critical for sensing applications, as they have physical and electronic properties which facilitate the detec...
Conference Paper
Full-text available
Carbon nanotubes (CNTs) are increasingly being used in the field of microelectronics, energy harvesting and upcoming green energy technologies. CNTs are composed of fused carbon rings with high electron angular momentum, attributing them unique surface electrostatic properties and strong adsorptive properties towards organic compounds. Removal of i...
Article
Benzo[a]pyrene is a known carcinogen, which derives from fossil fuel combustion, cigarette smoke, and generic biomass combustion including traffic emissions. This potent carcinogen has a well-known mechanism of action, leading to the formation of adducts with the DNA, primarily at guanosine positions. The reactivity and chemistry of this notorious...
Article
The Arctic Ocean is a large aquatic ecosystem stretching 14,056,000 km2 across the Northern Hemisphere, and hosts a multitude of marine species, avian species, and the well-known polar bear in its domain. The Arctic Ocean is the most remote ocean in the world and has been inaccessible to traffic and oil-drilling activities until recent years. Howev...
Article
Industrialism has brought a long series of benefits for modern civilization. Concomitantly, reversible and irreversible changes have been inflicted upon the environment, affecting humans, animals and whole ecosystems, leading to effects such as declining reproduction in modern human beings, developmental challenges on various species and destroyed...
Article
This study reports the structure and electronic properties of three stable endohedral X@Si20F20 and exohedral X-Si20F20 (X=O2−, S2−, Se2−) complexes. The study revealed that the endohedral complexes with S2− and Se2− result as energy minimum structures, with the guest anion located in the cage center. In the case of endohedral O2−-complexes, the pa...
Article
Vitamins are crucial components in the diet of animals and many other living organisms. One of these essential nutrients, thiamin, is known to be involved in several cell-functions, including energy-metabolism and the degradation of sugars and carbon skeletons. Other roles that are connected to this vitamin are neuronal communication, immune system...
Article
Antibiotics have been used as medical remedies for over 50years and have recently emerged as new pollutants in the environment. This review encompasses the fate of several antibiotics in the environment, including sulfonamides, nitrofurans, terfenadines, cephalosporins and cyclosporins. It investigates the cycle of transfer from humans and animals...
Chapter
Full-text available
The world's air pollution problems are increasingly been related to automotive exhaust emissions. The implementation of diesel and biodiesel blends in passenger vehicle engines have gradually produced a new ecotoxicological profile of urban and rural air pollution, where nanoparticles, volatile exhaust fractions, microparticles and aerosol agglomer...