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Sergio Lerma Lara

Sergio Lerma Lara
Centro Superior de Estudios Universitarios La Salle. UAM · Health Sciences Faculty.

PT, MSc, PhD.

About

102
Publications
36,087
Reads
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806
Citations
Citations since 2016
71 Research Items
782 Citations
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2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
Additional affiliations
September 2012 - present
Universidad Autónoma de Madrid
Position
  • Professor

Publications

Publications (102)
Article
Full-text available
The purpose of this work is to study the gap between the research evidence and the clinical practice in the physical rehabilitation of people with cerebral palsy. A review process was performed to (1) identify physical therapies to improve postural control in children with cerebral palsy and (2) determine the scientific evidence supporting the effe...
Article
Full-text available
Objective: To describe the quality of life and daily functioning of Spanish children and adolescents living with Stickler syndrome (SS) and to estimate the prevalence of associated disease features in a representative sample. Methods: A cross-sectional study of children and adolescents with SS were recruited via telephone calls through the Spani...
Chapter
Objective: This study presents the design and evaluation of goal-directed arm tasks using a customised exoskeleton for children with motor disabilities (MD). A further aim was to investigate the suitability of using video games or virtual reality as motivational technologies for gamified functional exercises. Methods: An upper limb exoskeleton and...
Article
Background The COVID-19 pandemic continues worldwide and has had a strong impact on public health. As the pandemic evolves, efforts have been intensified to identify persistent symptoms associated with the infection once resolved have intensified. Objectives We aimed to describe persistent symptoms and sequelae in patients with rheumatic and muscu...
Article
Full-text available
Objectives We aimed to describe persistent symptoms and sequelae in patients with rheumatic and musculoskeletal diseases (RMD) after admission due to Covid-19, assessing the role of autoimmune rheumatic diseases (ARD) compared with and non-autoimmune rheumatic and musculoskeletal diseases (NARD) on persistent symptoms and sequelae. Methods We perf...
Article
Full-text available
Introduction: Facial paralysis (FP) is a neuromuscular disorder caused by facial nerve injury. There are two main types of FP (which can be either primary or secondary): central and peripheral; Procedure of cases: This case series presents five patients with facial paralysis with different etiologies. In all cases, we assessed the facial disability...
Article
Introduction: Different variables, such as repetition and cognitive load, may explain the neurophysiological differences observed from one task to another in motor learning. This learning can be measured with functional magnetic resonance imaging. Aim: The aim of this systematic review was to document motor learning by functional magnetic resona...
Article
Full-text available
Transcranial direct current stimulation (tDCS) has been investigated as a way of improving motor learning. Our purpose was to explore the reversal bilateral tDCS effects on manual dexterity training, during five days, with the retention component measured after 5 days to determine whether somatosensory effects were produced. In this randomized, tri...
Poster
Full-text available
Tele-rehabilitation has become a hallmark in children rehabilitation during the Covid-19 pandemic, and motor interventions as home-based exercise programs, active video gaming and low-cost virtual reality play a fundamental role in it. Even though they have been previously described in contexts where a continuous face-to-face follow-up is not possi...
Article
Full-text available
We analyzed the inter- and intra-examiner reliability of Werium inertial sensors and the cervical range of motion (CROM) instrument for the measurement of active CROM (AcROM) in patients with primary headache. Another objective is to analyze the validity of the inertial sensors (Werium). The literature has reported symptomatology features in patien...
Article
Full-text available
The main aim was to assess the short-term efects of active-tDCS (a-tDCS) in the primary motor cortex (anodal stimulation-M1) on sensorimotor variables. These variables included discriminative sensation through the two-point discrimination (2-PD) test, tactile acuity threshold and pressure pain threshold (PPT), and electromyographic (EMG) activity c...
Preprint
OBJECTIVES: To describe persistent symptoms and consequences in Rheumatic and Musculoskeletal diseases (RMD) discharged from the hospital after Covid-19; to assess the roll of autoimmune rheumatic diseases (ARD) compared to and non-autoimmune rheumatic and musculoskeletal diseases (NARD) on persistent symptoms and consequences. METHODS: We performe...
Article
Full-text available
Background: Transcranial direct current stimulation (tDCS) of the motor cortex (M1) produces short-term inhibition of pain. Unihemispheric concurrent dual-site tDCS (UHCDS-tDCS) over the M1 and dorsolateral prefrontal cortex (DLPFC) has greater effects on cortical excitability than when applied alone, although its effect on pain is unknown. The ai...
Article
Objetivo: Evaluar cuantitativamente mediante posturografía la mejora en el equilibrio después de una intervención con ejercicio terapéutico basado en un programa de fuerza y resistencia muscular. Evaluar cambios en Kinesiofobia asociados a la intervención mediante la versión española de la Escala Tampa de Kinesiofobia (TSK-11SV). Material y métodos...
Preprint
Full-text available
Background: Objectives. The objective of this study was to compare the efficacy of direct current stimulation (DCS) applied at the transcranial, suboccipital and spinal level on experimental sensory modalities and pain outcome measures in healthy subjects. The hypothesis of this study was that systematic analysis of the efficacy of DCS on modulatin...
Article
Full-text available
Objetivo: Determinar los efectos de la imaginería motora sobre el control postural en bipedestación, postural de partida de una gran variedad de ocupaciones humanas.Diseño: Estudio piloto experimental, de corte longitudinal.Marco: Ámbito universitarioParticipantes: Quince sujetos sanos de ambos sexos, con edades comprendidas entre los 18-30 años.In...
Article
Objectives: The method of measuring the cervical active range of motion (aROM) has changed over the years, starting with the universal goniometer (UG) and continuing with the cervical range of motion. Current literature is scarce about the use of an inertial sensor to measure cervical aROM. The objective of the present study is to determine inter-...
Article
Full-text available
Background: Research efforts in neurorehabilitation technologies have been directed towards creating robotic exoskeletons to restore motor function in impaired individuals. However, despite advances in mechatronics and bioelectrical signal processing, current robotic exoskeletons have had only modest clinical impact. A major limitation is the inab...
Article
Introduction: The quantification of knee range of motion is a clinically relevant measurement in the healthcare setting, as its decrease can alter activities of daily living. Collecting reliable measurements of the range of motion allows us to evaluate the reliability of interventions, or the severity of the pathology. The objective of this study w...
Article
Full-text available
This investigation evaluated the reliability and validity of the 6‐Minute Walk Test (6MWT) in patients with pediatric hypophosphatasia (HPP). Children (aged 6–12 y; n = 11), adolescents (13–17 y; n = 4), and adults (18–65 y; n = 9) completed the 6MWT at Screening and Baseline in 2 clinical studies of asfotase alfa. Test‐retest reliability of the 6M...
Article
Full-text available
Background The use of robotic trainers has increased with the aim of improving gait function in patients with limitations. Nevertheless, there is an absence of studies that deeply describe detailed guidelines of how to correctly implement robot-based treatments for gait rehabilitation. This contribution proposes an accurate robot-based training pro...
Article
Full-text available
To compare medial gastrocnemius muscle-tendon structure, gait propulsive forces, and ankle joint gait kinetics between typically developing children and those with spastic cerebral palsy, and to describe significant associations between structure and function in children with spastic cerebral palsy. A sample of typically developing children (n = 9...
Article
Resumen Objetivos: La marcha es la forma de desplazamiento del ser humano. La interrelación fisiológica entre el sistema muscular y vascular ha sido poco estudiada. Conocemos la importancia de la bomba soleogemelar sobre el sistema venoso durante la marcha, por lo que proponemos un método de estudio de la hemodinámica venosa durante la marcha, un e...
Preprint
Full-text available
BACKGROUND The use of robotic trainers has increased with the aim of improving gait function in patients with limitations. Nevertheless, there is an absence of studies that deeply describe detailed guidelines of how to correctly implement robot-based treatments for gait rehabilitation. This contribution proposes an accurate robot-based training pro...
Article
There are several evidences showing that motor disorders in patients with cerebral palsy are associated with problems in motor planning, which, in turn, denote a diminished capability to imagine movements. Motor imagery appears like an effective means in learning and acquiring motor skills since it shares similar neural structures to those ones use...
Conference Paper
Full-text available
Gait limitation is one of the main impairments in children with Cerebral Palsy (CP). Robotic trainers appeared with the aim of improving the traditional therapies, and its use has been increased in the last years. However, so far there are not guidelines that deeply describe how to correctly implement robot-based gait treatments. This contribution...
Article
Full-text available
Existen diversas evidencias que indican que los déficits motores en los pacientes de parálisis cerebral se asocian con problemas en la planificación motora que, a su vez, apuntan a una mermada capacidad para imaginar movimientos. La imaginación motora se ha revelado como una herramienta efectiva en el aprendizaje y la adquisición de habilidades mot...
Article
Full-text available
Objectives Compare the immediate effects of a Neurodynamic Mobilization (NM) treatment or foam roller (FR) treatment after DOMS. Design Double blind randomised clinical trial. Setting The participants performed 100 drop jumps (5 sets of 20 repetitions, separated by 2 min rests) from a 0.5-m high box in a University biomechanics laboratory to indu...
Chapter
Cerebral Palsy (CP) is the most common cause of permanent serious physical disability in childhood. New strategies are needed to help promote, maintain, and rehabilitate the functional capacity of children with severe level of impairment. The main objective of this work is to present a Human-Robot interaction strategy for overground rehabilitation...
Article
Purpose: Corticoid-induced osteonecrosis (ON) of femoral head can lead to severe hip joint impairment and hip replacement, with negative impact in young survivors of acute lymphoblastic leukaemia (ALL) with long life expectancy. We aim to improve quality of life in these patients with a novel approach. Methods/patients: Based on the regenerative...
Conference Paper
Full-text available
El uso de dispositivos robóticos para rehabilitación de la marcha se ha incrementado en los últimos años de manera notable. Sin embargo, hay una falta de estudios que proporcionen pautas detalladas sobre cómo usar la robótica de rehabilitación para obtener los máximos beneficios del tratamiento. Esta contribución presenta un programa de entrenamien...
Article
Tissue related ankle hyper-resistance has been reported to contribute to equinus gait in children with spastic cerebral palsy. Hence, ankle plantarflexor stretching programs have been developed in order to restore passive ankle dorsiflexion. Despite high quality evidence on the limited effects of stretching on passive joint mobility, further muscle...
Article
Full-text available
Muscle fascicles lengthen in response to chronic passive stretch through in-series sarcomere addition in order to maintain an optimum sarcomere length. In turn, the muscles’ force generating capacity, maximum excursion, and contraction velocity is enhanced. Thus, longer fascicles suggest a greater capacity to develop joint power and work. However,...
Conference Paper
Background Transition is the process by which a young patient with a chronic disease is able to develop skills and have access to resources to ensure that physical, psychological, educational and vocational needs are covered during the stage from youth to adulthood. According to SERPE and EULAR/PReS recommendations, the goal of transition programs...
Article
Background and purpose: To support clinical decision-making in central neurological disorders, a physical examination is used to assess responses to passive muscle stretch. However, what exactly is being assessed is expressed and interpreted in different ways. A clear diagnostic framework is lacking. Therefore, the aim was to arrive at unambiguous...
Chapter
Motor rehabilitation strategies by means of neuro-modulation paradigms, taking advantage of the motor predictive characteristics of the electroencephalographic signal, are currently subject to extensive research. Such rehabilitation strategies follow a top-down approach in which targeted neurophysiological changes in the central nervous system are...
Poster
Full-text available
Descriptive study on lower limb pain caused by spasticity in children with spastic type cerebral palsy.
Article
The term Cerebral Palsy (CP) is a set of neurological disorders that appear in infancy or early childhood and permanently affect body movement and muscle coordination. The prevalence of CP is two-three per 1000 births. Emerging rehabilitation therapies through new strategies are needed to diminish the assistance required for these patients, promoti...
Article
Full-text available
Background Cerebral Palsy (CP) is a disorder of posture and movement due to a defect in the immature brain. The use of robotic devices as alternative treatment to improve the gait function in patients with CP has increased. Nevertheless, current gait trainers are focused on controlling complete joint trajectories, avoiding postural control and the...
Conference Paper
Eccentric and explosive strength training have the potential to stimulate in-series sarcomere addition in children with cerebral palsy (CP), as previously seen in typically developing children. This adaptation would enable greater muscle power generation. Similarly to previously used ankle robotic therapy, we believe the CPWalker robotic platform i...
Conference Paper
Full-text available
Resumen La Parálisis Cerebral (PC) está relacionada con un trastorno de la postura y el movimiento debido a una lesión ocasionada en el cerebro cuando éste no se ha desarrollado completamente. Al ser una de las discapacidades más prevalentes a edades tempranas, la investigación y el desarrollo de dispositivos robóticos para la rehabilitación de la...
Conference Paper
Introduction: Cervicogenic dizziness is a musculoskeletal disorder mainly characterized by dizziness and imbalance associated with neck pain [1,2]. Proopioceptive input from the neck helps in the coordination of eye, head and body posture as weell as spatial orientation [3,4]. The aim of this study is to compare the activity of the vestibular-ocula...
Poster
Full-text available
Several robotic platforms were recently developed aimed at improving the locomotion capacity of people with gait impairment. Most of these gait trainers are limited to treadmill training, which is not a motivating condition for children with cerebral palsy (CP) and related disorders. This contribution presents a pilot study done with three children...
Article
Abstract BACKGROUND: Cervicogenic dizziness is a musculoskeletal disorder mainly characterised by dizziness and disequilibrium associated with neck pain. The pathophysiology is unclear and the neurophysiological basis remains to be ascertained. The aim of this study is to compare the vestibulo-ocular reflex and postural control between patients wit...
Article
Full-text available
Background: Cervicogenic dizziness is a musculoskeletal disorder mainly characterised by dizziness and disequilibrium associated with neck pain. The pathophysiology is unclear and the neurophysiological basis remains to be ascertained. The aim of this study is to compare the vestibulo-ocular reflex and postural control between patients with cervic...
Article
Full-text available
The purpose of this study was to evaluate the effectiveness of a treatment for patients with cervicogenic dizziness that consisted of therapeutic education and exercises. The Dizziness Handicap Inventory and Neck Disability Index were used. Secondary outcomes included range of motion, postural control, and psychological variables. Seven patients (t...
Conference Paper
Several robotic platforms were recently developed aimed at improving the locomotion capacity of people with gait impairment. Most of these gait trainers are limited to treadmill training, which is not a motivating condition for children with cerebral palsy (CP). This paper presents a pilot study done with two children with spastic CP, who trained w...
Conference Paper
Cerebral Palsy (CP) is the most common cause of permanent serious physical disability in childhood. New strategies are needed to help promote, maintain, and rehabilitate the functional capacity of children with severe level of impairment. Overground walking rehabilitation devices appear as an alternative treatment for improving gait performance as...
Presentation
Full-text available
1. Background: With growth, fascicle lengths increase through sarcomere addition to maintain force production(1), however, children with cerebral palsy (CP) present in-series sarcomere reduction(2). Regarding fascicle lengths of the medial gastrocnemius (MG) in children with CP, some studies show smaller fascicle lengths than typically developing (...
Article
Hypophosphatasia (HPP) is a rare inborn error of metabolism resulting in undermineralization of bone and subsequent skeletal abnormalities. The natural history of HPP is characterized by rickets and osteomalacia, increased propensity for bone fracture, early loss of teeth in childhood, and muscle weakness. There is a wide heterogeneity in disease p...