Sergii Vladimirovich Kozlov

• Professor
• Researcher at Dnipro State Medical University

Since the beginning of the Russian Federation's invasion of Ukraine in 2022, explosive trauma has become an extremely urgent problem, as the main source of bodily injury among both the military in the combat zone and the civilian population in cities has been the impact of explosive devices. The aim of the study is the examination of the forensic c...

The using of explosive substances and devices can lead to brain injuries, the diagnosis of which requires the determination of primary biomarkers. Therefore, the aim was to establish and study histopathological and ultrastructural changes in the rats brain after exposure to an air blast wave. The study was carried out on 18 male Wistar rats, which...

Mild blast-induced traumatic brain injury is common among the military, resulting in cognitive impairment, reduced socialization, which leads to disability and, as a result, a deterioration in the quality of life. It is considered that blood-brain barrier disruption and microvascular dysfunction are the key to this type of injury. The purpose of st...

The aim was to evaluate the markers of emotional status and the antioxidant system activity in rats with blast-induced traumatic brain injury. Materials and methods. The study carried out on 85 sexually mature male Wistar rats in compliance with the current legislation on humane treatment of animals. The selected rats were randomly divided into thr...

Тиреоїдні гормони мають ключову дію на центральну нервову систему. Дисфункція щитоподібної залози є однією з основних причин когнітивних порушень, особливо в похилому віці, але особливості цих змін залишаються нез’ясованими. Мета дослідження – вивчити особливості формування просторової пам’яті в старих щурів за гіпер- і гіпотиреоїдизму. Поведінкову...

Background: In connection with the widespread use of explosive devices in military conflicts, in particular in Ukraine, is relevant to detect the biometals changes in the cerebellum and determine the presence of their influence on the behavior changes of rats in the elevated plus maze in the acute period of a mild blast-traumatic brain injury (bTB...

Explosions are physical phenomena that lead to a sudden release of energy; they can be chemical, nuclear or mechanical. This process results in an almost instantaneous increase in pressure above atmospheric pressure. Damage to the abdominal organs after the action of explosion factors (shock blast wave, striking elements of the explosive device, se...

The purpose of the study was to investigate, analyze and evaluate the expression level of HIF1A and parenchymal-stromal relations after traumatic air shock wave exposure to the liver. Materials and methods. The material for the study was the liver of 30 male rats, weighing 177.5 ± 15.8 g. All animals were randomly divided into three groups: group 1...

Spatial-temporal distribution of expression of liver injury markers according to the results of immunohistochemical analysis after exposure to an air shock wave. ABSTRACT. Background. The liver is one of the most vulnerable organs of the abdominal cavity after the blast wave. Diagnosis of closed liver injury, which is not accompanied by acute intra...

ABSTRACT. Background. Justification of the expediency and effectiveness of the application of a complex approach in the identification of the bodies of the dead in the conditions of an armed conflict with mass casualties. Object of research: an- thropometric, morphological, biochemical, physical changes in the human body that occur during armed con...

Background. Closed blunt trauma to the abdomen, which is accompanied by liver injury of any degree, is life-threatening. Injury to the liver leads to a violation of numerous components of the synthesizing, detoxification, digestive and metabolic functions of the body. In this regard, the diagnosis and proper treatment of liver lesions is an extreme...

The article presents generalized data on the possibility of using dermatoglyphic characteristics of a person in terms of the latest approaches to the identifi cation of an unknown person. Morphological characteristics of papillary patterns of hands and feet, their topography and types are given. Quantitative and qualitative features of dermatoglyph...

Вивчено зміни компонентів поведінки в піднесеному хрестоподібному лабіринті у щу­рів зі сформованою вибухо-індукованою нейротравмою, гіпо- та гіпертиреозом. Екс­перимент проводили на 33 щурах-самцях лінії Вістар, які утримувались в стан­дарт­них умовах та на стандартному раціоні віварію Дніпровського державного медичного університету відповідно до...

This study is aimed to develop a computer program to analyze the color properties of raster images of histological microspecimens used in pathological anatomy and forensic medicine. When developing a computer program, we used the system for building client applications – Windows Presentation Foundation (WPF). The system allows you to create applica...

The search for specific and characteristic changes in the liver parenchyma in the conditions of reproduction of theexplosion factors action is one of the solutions to the problem of diagnosing explosion-induced liver injury. Forty-twoliver livers of adult white male rats were used as material. All rats were randomly divided into three groups (intac...

ABSTRACT. Background. Recently, interest in blast-induced brain injuries has been increasing due to military events and the use of explosive devices in eastern Ukraine. Considering the diagnostic uncertainty regarding the specific signs of brain injury after the distant action of an blast shock wave, the danger of prognostic consequences, the incre...

The work is aimed at the development and experimental testing of the polarization-correlation method for the analysis of the polycrystalline structure of biological layers. introduced a new parameter-complex degree of mutual anisotropy. the statistical (statistical moments of the 1st-4th orders) structure of the distributions of the values of the c...

ABSTRACT. Background. Recently, interest in blast-induced brain injuries has been increasing due to military events and the use of explosive devices in eastern Ukraine. Considering the diagnostic uncertainty regarding the specific signs of brain injury after the distant action of an blast shock wave, the danger of prognostic consequences, the incre...

Objective: The aim is to identify the morphological features of the uterus layers in women at different time intervals of the postmortem period as diagnostic criteria for establishing the postmortem interval. Patients and methods: Materials and methods: In the study we used surgical and autopsy material - uterine tissue fragments. All materials...

Вивчено зміни компонентів поведінки в піднесеному хрестоподібному лабіринті у щу­рів зі сформованою вибухо-індукованою нейротравмою, гіпо- та гіпертиреозом. Екс­перимент проводили на 33 щурах-самцях лінії Вістар, які утримувались в стан­дарт­них умовах та на стандартному раціоні віварію Дніпровського державного медичного університету відповідно до...

The paper considers scientific works devoted to the mechanisms and differential diagnosis of closed injuries of the brain, liver and kidneys due to blunt and explosion-induced injuries. Analysis of the literature has shown that the mechanism of development of primary explosion-induced injuries remains controversial, and the search for biomarkers, i...

In recent years, injuries of the abdominal cavity, in particular the intestine, have become increasingly important in abdominal surgery. The aim of our study was to analyze the ultrastructural changes of the small intestinal wall after abdominal barotrauma. Analysis of histological signs of the intestinal wall of experimental animals in the first h...

Information about the differential diagnosis of human bodily injuries, which were formed when the body, wheel and bottom of a modern car came into contact with the body of a pedestrian; a person on the road surface, in the cabin of a modern car (driver and passengers), when a cyclist comes into contact with a car, in cases of combined types of car...

The article represents the results of data analytical processing considering the equivalent for dental treatment cost estimation among victims of traffic accidents with dental and maxillofacial injuries, and analyzes the objective association level of this criterion with the parameters of the approaches used for expert assessment of maxillofacial t...

Summary. In the present observation, this picture is typical of the damage that could be dealt with explosion manual remote grenades. Feature provides expert case is the ability to localize the damage determining the position of multiple victims at the moment of explosion for the subsequent reconstruction of the circumstances of the incident. Keywo...

Summary. The publication is devoted to an actual problem - postmortem diagnostics an explosive trauma. The work presents the features of body injuries, the contents of wound channels in the explosions of the fragmentation grenade VOG-17M. The obtained data allow identification of an explosive device and conduct differential diagnostics with the ope...

Summary. In the present observation, this picture is typical of the damage that could be dealt with explosion manual remote grenades. Feature provides expert case is the ability to localize the damage determining the position of multiple victims at the moment of explosion for the subsequent reconstruction of the circumstances of the incident. Keywo...

Summary. The article is devoted to an actual problem - postmortem diagnosis of blast injuries. It is known that the main cause of injury and death in modern military conflicts are explosions of mines, shells, bombs. The article describes the features of injuries in the blasts the most common anti-personnel mines. When forensic human corpses brought...

An increased number of injury cases caused by firearms in Ukraine makes it important to improve the accuracy and objectivity of forensic medical examinations in this type of injury by using modern optical research methods, in particular, autofluorescence spectral analysis. Archival material of the Chernivtsi Regional Bureau of Forensic Medical Exam...

Резюме. В статті наведений аналіз можливостей комплексної судової медико-автотехнічної експертизи у випадках автотравми водія та декількох пасажирів. Показано, що комплексна медико-автотехнічна експертиза, як наукове дослідження обставин подій, судово-медичних та автотехнічних об'єктів, є потужним доказовим інструментом при вирішенні слідчих за-вда...

The work is devoted to the analysis of the existing polari-zational methods of investigation of the body's tissue and determination of effectiveness when using lazer polarizational methods of the research of ischemic damages taking acute myocardial ischemia as an example. The necessity of the search and development of the newest methodics has becom...

The pathomorphological microscopic changes in the brain, identifi ed in the study on the died of explosive traumas, can be used for diagnostic purposes in conjunction with other characteristic signs of explosive trauma in forensic and pathological studies. The complex of microscopic signs in the head brain, i.e. separation of blood vessel walls fro...

Introduction and purpose of the study: high require­ments for graduates of higher medical establishments facilitate the search, implementation and improvement of modern teaching methods in order to optimize the development of clinical thinking in medical students. In the the course of the work, a big volume of information was used, which was worked...

Pathological changes in the heart under the use of psychostimulants The aim of the work is to study pathomorphological changes in the heart in cases of death under the use of phenylalkylamine derivatives. Materials and methods. 58 forensic studies of people who died of poisoning with drugs during the period 2015–2017 in the Dnipropetrovsk region w...

Under conditions of the open field test, 30 control Wistar rats and 30 rats with experimental cardiomyopathy (CMP) were examined with recording of four behavioral indices, (i) number of crossed squares (intensity of locomotion), (ii) number of rearings (vertical stands), (iii) number of examined holes in the arena, and (iv) number of grooming episo...

Матка кровоснабжается за счет двух пар маточных и яичниковых артерий, мелких ветвей яичниковых артерий и артерий круглых связок матки. В 60% случаев маточные артерии являлись ветвями передних стволов внутренних подвздошных артерий. В ряде наблюдений маточная артерия представляла собой ветвь необлитерированной части пупочной артерии (27%), нижней п...

Резюме: у статті наведений докладний аналіз судово-медичних літературних джерел, на підставі якого слід дійти до висновку про те, що загальноприйнятого поняття автомобільної травми на даний час не існує, до того ж, будь-яке сформульо-ване визначення автомобільної травми страждає неповнотою. Автори підкреслюють необхідність розробки універсального п...

За допомогою методики скануючої електронної мікроскопії встановлено морфологічні особливості внутрішньої поверхні камер серця білих щурів за умов фізіологічної норми. Як матеріал для скануючої мікроскопії використали стінки правого і лівого передсердь та шлуночків з боку камер серця. Приготування препаратів здійснювали за загальновідомою методикою....

The article is devoted to an actual problem - postmortem diagnosis of blast injuries. It is known that the main cause of injury and death in modern military conflicts are explosions of mines, shells, bombs. The article describes the features of injuries in the blasts the most common anti-personnel mines. When forensic human corpses brought from the...

In this paper by the results of immunohisto-chemical, morphometric studies of vascular endothe-lium in the heart of 21 human fetuses 18-24 weeks gestation topological differences in the spatial distri-bution of vascular elements in the ventricles and atria have been determined. Considering selective speci-ficity of the endothelial marker CD 31, the...

In this paper by the results of immunohistochemical, morphometric studies of vascular endothelium in the heart of 21 human fetuses 18-24 weeks gestation topological differences in the spatial distribution of vascular elements in the ventricles and atria have been determined. Considering selective specificity of the endothelial marker CD 31, the mor...

Background. Injuries are 3rd in the structure of the population mortality. Over the past 15 years, mortality from injury came on second place, ahead of cancer. Traumatic brain injury is the most common damage types and ranges from 36 to 40 % of all injuries. The incidence of posterior fossa hematomas among intracranial hematomas has been reported t...

Background. The concept of "positional asphyxia" is considered as a separate type of mechanical asphyxia. Objective. Determination of morphological features characteristic of deaths resulting from "positional asphyxia". Results. The concept of "positional asphyxia" – a separate type of mechanical asphyxia, and the risk factors leading to death. We...

In the present observation, this picture is typical of the damage that could be dealt with explosion manual remote grenades. Feature provides expert case is the ability to localize the damage determining the position of multiple victims at the moment of explosion for the subsequent reconstruction of the circumstances of the incident.

Purpose: Investigation of the mechanisms of occlusion of the vertebral arteries, radicular medullary arteries and the formation of ischemic of the brainstem. Methods: We conducted two morphological examinations in the presence of spinal cord trauma in the cervical spine. In the first study we investigated the injured vertebral artery, and in the se...

Background. Cardiovascular disease is a major cause of human mortality and disability at working age. Many disorders of cardiac sarcomeres components have been linked to human cardiomyopathies, including desminopathy, dilated cardiomyopathy, hypertrophic cardiomyopathy, familial atrial septal defects, and others. Objective. The aim of this work was...

Проведено кількісний і якісний аналіз формування мітохондріома скоротливих кардіоміоцитів на етапах постнатального онтогенезу в нормі. Показано, що від 1-го до 5-го дня спостерігається достовірне збільшення питомого об’єму мітохондрій, яке супроводжується ускладненням ультраструктурної організації органел. Після 20-го дня постнатального онтогенезу...

The article highlights the current state of diagnosing the acute ischemic myocardial injury. The possibilities of application of various additional methods of research and their effectiveness have been considered. Taking into consideration the shortcomings of most of the known methods of diagnosing and the state of ensuring the regional bureaus of...

Резюме. У статті висвітлено сучасний стан про-блеми діагностики гострого ішемічного пошкодження міокарда. Розглянуто можливості застосування різно-манітних додаткових методик дослідження та їх ефек-тивність. Беручи до уваги недоліки більшості відомих методів діагностики та стан забезпечення обласних бюро судово-медичної експертизи, обґрунтовано нео...

Modern data in relation to the problem of establishing the prescription of death coming in a late postmortem period are presented. We have determined problem question, set goals and formulated tasks to realize modern approaches in diagnosing the prescription of death coming. To our way of thinking, an elaboration of a complex program of research of...