Sergey MinaevStavropol State Medical University · Pediatric Surgery
Sergey Minaev
Doctor of Medicine
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Publications (100)
Introduction . Primary acquired cryptorchidism is the absence of a testicle into the scrotum in a boy with a descended testicle previously documented. In our country, the fact that such pathology exists is denied. However, this disease is recognised by many foreign urological associations of urologists.
Objective. To analyse the accumulated researc...
BACKGROUND: The new coronavirus pandemic has dramatically impacted our lives. This study aimed to analyze the structural changes in providing emergency surgical care to children during the COVID-19 pandemic. AIM: The purpose of this work was to analyze. MATERIALS AND METHODS: We compared the number of people seeking emergency surgical care in the e...
The use of platelet-rich plasma (PRP) in clinical settings is a current issue in various fields of medicine. There is no unified and structured approach to PRP preparation and application stages. This review examines the literature data on the use of PRP in surgical practice. Data were analyzed using scientific sources from scientific citation plat...
Introduction. The cutaneous larva migrans syndrome is a common disease in the tropical zone. But in the countries with a different climate , like in Russia, this pathology is rarely met; thus, practicing physicians have not enough experience and knowledge about this disease .
Clinical observation. The authors describe their experience in treating c...
Introduction . Cryptorchidism is a common disease in pediatric urological and andrological practice since the issues of tactical approaches and its optimal treatment remain extremely relevant. Cryptorchidism makes a significant contribution to the structure of male infertility.
Objective . To conduct a retrospective analysis of treatment results in...
Aim - histological study of the structure and thickness of the membranes of the portal vein of the liver and splenic vein in people of different age groups in normal conditions and with portal hypertension. Materials and methods. Sectional material for the study of the portal vein of the liver and splenic vein was obtained from 89 people aged 7 to...
The Electronic Clinical Pharmacologist (ECP) is a Medical Decision Support System (MDSS). This system is based on the Unified Medical Knowledge Base (UMKB), which is updated and updated as new medicines are released and specialized publications are published in peer-reviewed biomedical scientific journals. ECP helps to reduce the risks of medical e...
BACKGROUND: Laparoscopy in the treatment of abdominal echinococcosis is accompanied by complications. Therefore, studies on optimizing surgical approaches that reduce intra- and postoperative complications in liver echinococcosis are extremely relevant. AIM: This study aimed to assess the possibility of using three-dimensional (3D) technologies in...
The combination of duodenal atresia (DA) with esophageal atresia with tracheoesophageal fistula (EA-TEF) is a rare pathology, the frequency of which ranges from 1% to 6% of all cases of EA. Surgical treatment of the DA+EA-TEF combination always causes significant difficulties, primarily in determining the timing and stages of surgical correction. O...
AIM: This study aimed to assess the formation of scar tissue after burns under the influence of an anti-scar gel. Understanding of the processes involving scars and the morphofunctional features of the tissue at different stages of development allows targeted selection of therapy and prevention of scars. MATERIALS AND METHODS: We conducted a compar...
Texture features are designed to quantitatively evaluate patterns of spatial distribution of image pixels for purposes of image analysis and interpretation. Unexplained variations in the texture patterns often lead to misinterpretation and undesirable consequences in medical image analysis. In this paper we explore the ability of machine learning (...
Objective:
To study the immunohistochemical features of various scar tissues in children without connective tissue pathology and with undifferentiated connective tissue dysplasia syndrome.
Material and methods:
Tissue biopsy was performed in 217 children who underwent surgical treatment for various lesions, such as injuries, burns, as well as ot...
Aim. To assess adhesions of the abdominal cavity in children with varying degrees of connective tissue dysplasia (CTD) severity. Methods. A total of 91 children with average age of 10.6 1.4 years were observed from 2005 to 2019. Composed of 53 boys (58.2%) and 38 girls (41.8%). Patients were divided into two groups: group 1 (69 children without CTD...
Currently, the problem of echinococcosis remains relevant, since this chronically ongoing and parasitic disease leading to disability occurs in different age groups. In this study, the goal was to conduct a morphological analysis of the fibrous capsule with adjacent liver tissues, depending on the type of echinococcal cysts. The analysis of histolo...
Objective:
To compare the effectiveness of multi-port and single-port laparoscopic surgery in the treatment of hydatid cyst of the liver.
Material and methods:
There were 25 children with solitary hydatid cyst of the liver (CL-CE2) who underwent surgery in 2013-2017. Mean age was 10.1±2.05 years. There were 17 boys and 8 girls. Patients were div...
The authors describe modern 3D technologies in hepatobiliary surgery. These approaches reduce the risk of intra- and postoperative complications. Virtual 3D reconstruction with clear visualization of parasitic cyst, adjacent vessels and bile ducts is valuable to create 3D-model of liver. This model may be applied for personalized laparoscopic appro...
Objective:
Was to evaluate the effectiveness of anti-scar treatment with Contractubex gel in children and adults.
Material and methods:
A group of researchers based on clinical hospitals and university medical clinics carry out the multicenter study to evaluate the effectiveness of anti-scar treatment with Contractubex gel containing cepalin, al...
Introduction. Currently, there is a limited number of works devoted to the comprehensive study of specific features of surgical treatment of patients with acute hematogenous osteomyelitis (AHO) which includes histological and immune histochemical (IHC) tests of the bone marrow at different periods of the disease. In this regard, the purpose of our...
The article describes the experience of application of the combined antiscar agent containing boswellic acid, cepalin, hyaluronic acid and allantoin with the subsequent application of the prolonged action pressing patch with the matrix of active release of cepalin and allantoin at the early stages of formation and maturation of scars in the patient...
The purpose of the study was to compare the effectiveness of various compression techniques with a prolonged-action patch on postoperative scars.
Material and methods:
The study included 21 patients aged 3.6±1.7 years who had scars after surgery. The patients were divided into two groups: group No 1 (n=11), in which they applied longitudinal patc...
The objective is to conduct a morphological analysis of the chitinous membrane area, the fibrous capsule of an echinococcal cyst with adjacent liver tissue, depending on the type of parasitic cyst. From 2008 to 2018, surgical treatment of 32 patients with liver echinococcosis was performed. After echinococcectomy, a histological and immunohistochem...
Background:
Chronic constipation in children is associated with primary megarectum. This study investigated outcomes of surgical treatment of idiopathic megarectum in children.
Methods:
This retrospective comparative study included 52 children with idiopathic megarectum (mean age, 9.4 ± 1.7 years) treated from 2007 to 2016. Patients were divided...
Material and methods:
In a prospective open-label randomized trial, 109 patients aged 5.3±2.1 years after surgery: boys - 73, girls - 36. Patients were divided into 2 groups: in the main group (54 children) the application of the prolonged plaster Contractubex was performed; in the control group (55 patients) - dynamic observation. The scar deform...
Epidemiological study of pyoinflammatory pathogens was conducted among 552 children at the Department of Purulent Surgery of the Regional Children's Clinical Hospital. The main etiologic causative agent of inflammatory lesion in children was Staphylococcus aureus (88.4 % of cases). The occurrence of multiple resistant strains of staphylococci and e...
The article presents a clinical case of successful surgical correction of the Pentada Cantrell. In a newborn child omphalocele, partial abdominal ectopia of the heart, the defect of the pericardium, diaphragm as well as an interventricular septal defect were diagnosed after birth. In the early neonatal period he has successfully undergone plastic s...
Umbilical granuloma is the most common umbilical abnormality in young infants and neonates. This prospective study was conducted on 21 infants (28-63 days old) with an umbilical granuloma. The treatment, performed in the patient's home, comprised application of common (edible) salt on the lesion twice a day for 5 days. Results were good in all case...
We present findings of a multicenter study investigating incidence of hydatid cysts in endemic regions of the Community of Independent States (CIS). Transmission of hydatid cysts depends on agricultural activity. The highest incidence in the CIS was observed in Yamal-Nenets Autonomous District (4.2±0.36 and 4.5±1.1 per 100,000 adults) and Republic...
Objective of the research - to improve results of fast-growing skin capillary hemangiomas treatment in children by applying silicone bandages after cryodestruction. Materials and methods: the study included 157 children aged 1-6 monthswith fast-growing skin capillary hemangiomas, 93 boys and 64 girls. Cryodestruction of hemangioma with liquid nitro...
Background:
There is no consensus on the surgical treatment of children with hydatid cyst of the liver (HCL). We evaluated the outcomes of laparoscopic and open surgery for childhood HCL.
Methods:
We performed 81 open surgery and laparoscopic procedures in 37 (45.7%) boys and 44 (54.3%) girls with HCL (mean age 9.3 ± 2.1 years) who were assigned...
Aim:
To investigate the complications of intestinal stoma in children and to develop measures for decrease of their incidence.
Material and methods:
The study included 152 children with congenital and acquired gastrointestinal pathology requiring surgical treatment with the imposition of intestinal stoma. Atresia of intestinal tube was observed...
Esophageal atresia is malformation which occurs 1 per 3000 to 1 per 5000 births. Nowadays cases with insuperable diastasis between segments of the esophagus are the most complex. Induction of esophageal growth by its extension proposed by Focker is one of the most popular methods of solving this problem. The clinical case of treatment of the child...
The study defined endoscopic criteria for congestive portal gastropathy in children with extrahepatic form of portal hypertension. The most significant endoscopic features were mosaic changes in the mucosa with foci of erythema and subepithelial hemorrhages, hyperemia with areas of the elevated edematous gastric mucosa by the type of mosaic.
Introduction. In the study determined accessible and highly specific morphological research techniques to diagnose the severity of the connective tissue dysplasia (CTD) in children with anomalies of the urinary system (AUS). Materials and methods. The work is based on the results of treatment of 143 children aged 6 months to 18 years with the diagn...
Interconnection of correlations of the acid-base blood balance with dysbiosis in 121 children with chronic constipation was found in the study. Metabolic acidosis is revealed with a high lactate concentration, emaciation of the organism buffer systems on the lowering background of main blood electrolytes and dehydration. And in its turn it takes pl...
The article is devoted to the analysis of the results of the application of nitrogen monoxide containing the gas stream in comparison with 0.05 % chlorhexidine solution in the treatment of purulent peritonitis in 61 patients. The positive effect of NO-therapy as a method of sanation in programmed relaparotomy has been shown.
The article presents the experience of minimally invasive surgery for hemorrhoids of II–III stages. The effect of both isolated and combined techniques was evaluated in 350 patients. The analysis of indications, clinical efficacy and disadvantages of minimally invasive procedures was carried out. A differentiated approach to the choice of the metho...
Background:
Operative correction of anorectal malformations (ARMs) remains a challenge in pediatric surgery. The study aimed to evaluate the outcomes of laparoscopic treatment of ARM in children.
Methods:
From 2007 to 2014, we performed 104 laparoscopic-assisted anorectal pull-through procedures in children with a mean age of 11.3 ± 0.4 months a...
The study determined accessible and highly specific morphological research techniques for diagnosing the severity of the connective tissue dysplasia (CTD) in children with hernias of the anterior abdominal wall. The main group consisted of 54 children with unilateral inguinal hernia, which had CTD of moderate or severe degree. The control group was...
In the article consider the actual problem of fast track in newborns with NEC. Patients were divided into two groups matched for gestational age, weight and sex of patients. The Group1 consisted of 18 infants with NEC stage 2 to 3, in which the complex treatment was provided using presacral blockade with ropivacaine. The Group 2 was represented by...
Case report of 1-year patient with damaging of Wilms' tumor (Stage IV). According to the current staging and treatment SIOP 9 protocol, patient received the preoperative chemotherapy. Harmonic Focus Scalpel provided reliable and safe option for Wilms' tumor resection in the child, lesser operative time and good postoperative recovery.
The aim of study was to determine the value of Doppler ultrasonography in the diagnosis of acute scrotal pain in the different stages of acute scrotum. The case notes of 344 boys with an acute scrotum aged from 1st day of life to 17 years old were reviewed in the Department of Pediatric Surgery of StSMU (Russia). The size and ultrasonography struct...
The level of BPI before surgery in group 2 was significantly higher than that in group 1 (10.5 ng/ml (3.35-19.05) and 3.33 ng/ml (2.74-4.51) p<0.05, respectively). In a group data comparison, BPI was significantly higher in group 1, even on the third day after surgery (2.915 ng/ml (1.37-55.5) and 15.75 ng/ml (3.32-50.5) p<0.05, respectively). The d...
Research of 30 histological specimen of colon (autopsy material of normal colon wall) allows differentiating 5 layers in its wall. At intraoperative ultrasonic research of a colon wall in patients with chronic constipation, specific changes like hyperechoic inclusions in a wall structures are taped, that allows to define a degree of the specified c...
The histological and hystometric structure of the spleen vein of norm and patients with portal hypertension has been studied in patients of different age groups: children aged 7-12, teenagers and adults aged 18-30. It was discovered that common thickness of spleen vein's wall increases with age and it could vary in various venous parts. Progressive...
A meta-analysis of extensive statistical data of "acute scrotal" syndrome in children was made. The two databases were considered. The first consisted of 1342 observations and described the nosologic structure of "acute scrotal" syndrome in children. The second included 440 patients and showed the long-term results of conservative treatment in chil...
Sixty children (age 3-15 years) with hydatid disease of the liver were treated. The patients were divided into 2 equal groups (control and main groups).The hydatid disease of the liver was revealed in 22 (33.6%) patients, combined hydatid disease of the liver and lung were noted in 38 (66.4%) patients. The "capitonnage" of the residual cavity was a...
From 1990 until 2010 retrospective study was carried out to investigate the occurrence of cystic echinococcosis (CE) of liver in children at Stavropol Regional children hospital in clinical wards of Stavropol State Medical Academy. We treated 60 children from 3 to 15 years with hepatic CE. In 22 (36.7%) patients had hepatic CE, in 38 (63.3%) — comb...
The first group included 45 patients with varicocele stage I-II; the second group included 20 patients with varicocele stage III. The ambulatory treatment complex permitted the inmprovement of of ultrasound indexes in scrotal veins in 29 (64%) patients of the 1st group, whereas nobody of the 2nd group showed any isignificant improvement. The proper...
Background. Newborns often develop purulent septic complications soon after surgical treatment of inherent gastrointestinal pathology. The aim: to define the prognosis significance of catelicidine (LL-37) as the marker of inflammatory complications during the post-operation period in neonates with gastrointestinal pathologies. Patients and methods....
The combination of even parts lidocaine and prilocaine in crème substance was used for surface anesthesia in 73 children, aged 1,5-16 years. Such surgical interventions as molluscum contagiosum eradication, laser wart resection and prepuce synechia dissection were performed. The described anesthetic was highly effective in all areas, but the nasola...
Intraperitoneal adhesions remain a common problem after abdominal surgery. However, the advent of targeted, specific agents as a directed therapy against inflammatory and neoangiogenesis raises the prospect of a new approach for anti-adhesion strategies.
70 adult rats were divided into two groups: an enzyme group (35 rats) and a control group (35 r...
An optimized therapeutic rehabilitation program involved 393 patients with fractured long bones (humeral, radial/ulnar, femoral, crural) admitted to the Orthopedic Department of the Stavropol Regional Children's Clinical Hospital and the Rehabilitation Centre for Handicapped Children and Adolescents. Rehabilitation was performed in three consecutiv...
The acute hematogenous osteomyelitis continues to remain at present one of the actual problems to pediatric surgery, being characterized by severe course, difficulty of the early diagnostics and frequency of unfavourable outcomes, becoming chronic and complications. We investigated the levels of CRP, IL-1beta, TNF-alpha in 74 children with acute he...
Adhesive process in the abdominal cavity is the leading cause of morbidity and mortality in abdominal surgery. The clinical investigation included 126 children with acute adhesive intestinal obstruction. All patients were divided into two groups: polyenzyme and monoenzyme groups. In the polyenzyme group there was one case of intestinal obstruction....
Ultrasound dopplerography of testicles and high-frequency ultrasonography of the spermatic cord were used to increase the efficiency of diagnostics at the acute scrotum edema in children. The signs of testicular torsion are the thickening of the spermatic cord from 7 to 33 mm, its helical structure (like cochlea), decrease or the termination of a b...
Conditions of activity of medical service of the Armed Forces of RF predetermines the necessity of utilizing new methods of organization of the process of access of medical-technical models and medical equipment, including complex equipment. The article presents several definitions, connected with aterm "medical technics and equipment". Medicine ch...
Intravaginal or extravaginal spermatic cord torsion is a diagnostic challenge for the surgeon and radiologist. Color Doppler sonography can be inaccurate, leading to dangerous false-negative results. To date, no single reliable test has been able to provide 100% diagnostic accuracy. The direct visualization of the twisted cord during emergency high...
The clinical investigation included 48 patients with acute adhesive intestinal obstruction resulting from appendectomy and an analysis of the cytokine status in 34 children with acute phlegmonous appendicitis. The patients were divided into two groups: a "polyenzyme" group and a "monoenzyme" group (Hyaluronidase). In the "polyenzyme" group the chil...
Results of treatment in 62 patients with varicocele were evaluated with anamnestic, physical and Doplerographic data. Recurrence of varicocele was seen after the Palomo surgery in 4.9% patients. Hydrocele reoccured after surgery in 2 teenagers. Doppler study revealed that 37.5% patients had orthostatic extravasal obstruction of the left renal vein...
The experimental clinical investigation of the influence of systemic enzymotherapy on the course of the wound process was carried out in rats and in clinic. The rats of the experimental group have demonstrated more rapid debridement of the wound from blood clots and tissue detritus, intensive formation of granular tissue and its ripening. The exper...