Semaa A. Shaban

Tikrit University · Department of Biology

Human cytomegalovirus (HCMV) is a well known hallmark of increasing morbidity and mortality in humans with acquired impairment in innate and adaptive immunity indicating high seroprevalence rate of 83%. This study aims to identify novel drug targets as disease biomarkers in HCMV-infected hosts. Thereby datasets were collected from NCBI SRA Database...

Genetic information is transformed from DNA to RNA and eventually to proteins. The protein phenotype is largely dependent on the mRNA produced during transcription. Isoform switching is a series of events that occurs after DNA is successfully transcribed into pre-mRNA, which can generate different transcripts from the same gene, leading to both str...

This study involved (50) patient’s that complaining rheumatoid arthritis from both genders (7 females and 43 males). Their ages range from (26-68) years there are taken from hospitals and clinics, in addition to the control which involve (30) person that look normal and their ages ranges from (23-54). Enzyme linked immuno-sorbent assay (ELISA) has...

Mycotoxins are natural toxins generally caused by some types of mold (fungi) that may be found in foods. Mold (Fungi) grows on (grains, nuts, spices, dried fruits, apples, and coffee seeds). Due to their effective impact on humans and animals, mycotoxins have gained a great deal of attention as studies have shown that mycotoxins are among the most...

A case-control retrospective study was conducted during January – June 2019 on 104 patients with asthma (50 females and 54 males) and 111 non-asthmatic healthy subjects matched patients for gender (54 females and 57 males) to assess role of total and specific IgE serum levels in patho-physiology of disease using ELISA and multiplex immunoblot kits....

This study sought to determine the significance of IL-33 in.pathogenesis of asthma in adult patients. Interleukin-33 (IL-33) is suggested to influence asthma pathogenesis. A case-control study was conducted on 104 asthma patients and 111 healthy subjects. Enzyme-linked immunosorbent assay was used to determine the IL-33 level. The median level of I...

The role of microRNAs (miRNAs) in the pathogenesis of cardiovascular disease has been extensively studied. miRNAs have been highlighted as an important physiological regulator for activities like cardiac protection. miRNAs are present in the circulation, and they have been investigated as physiological markers, especially in the condition of heart...

Introduction and Aim: Asthma is known as a polygenic and multifactorial disease. The underlying debate about the role of genetics in the development of asthma is still unclear. The objectives of this research are to examine whether the GSTM1 and GSTT1 gene polymorphisms are associated with asthma susceptibility. Materials and Methods: A total of 70...

Cancer is a major health issue worldwide. cfDNA integrity has been reported as a potential diagnostic molecular marker for different types of cancer, identifying the importance of liquid biopsy. The aim of this review was to evaluate the prognostic and diagnostic performance of Arthrobacter luteus (ALU) repeat in tumor. Following a thorough review...

Cancer is a major health issue worldwide. cfDNA integrity has been reported as a potential diagnostic molecular marker for different types of cancer, identifying the importance of liquid biopsy. The aim of this review was to evaluate the prognostic and

Tuberculosis (TB) is one of the most common diseases worldwide. Mycobacterium tuberculosis (Mtb) is the main causal agent of tuberculosis. Changes in gene expression are very important for normal biological functions. Changes in gene expression have adverse effects and cause many diseases. Tb is one of them. Gene expression is controlled by many sm...

Mycotoxins are natural toxins generally caused by some types of mold (fungi) that may be found in foods. Mold (Fungi) grows on (grains, nuts, spices, dried fruits, apples, and coffee seeds). Due to their effective impact on humans and animals, mycotoxins have gained a great deal of attention as studies have shown that mycotoxins are among the most...

Photosynthesis seems to be a central process which converts the sunlight to energy, thereby promotes plant proliferation and development, and leads to the maintenance of life on the earth by using water to introduce oxygen into the environment. Increased plant photosynthesis has recently been revitalized as a strategy to increase yields of crops an...

th 13 Photosynthesis seems to be a central process which converts the sunlight to energy, thereby promotes plant proliferation and development, and leads to the maintenance of life on the earth by using water to introduce oxygen into the environment. Increased plant photosynthesis has recently been revitalized as a strategy to increase yields of cr...

Human β-defensins (HBD), an antimicrobial peptide encoded by the (DEFB) gene. In humans they play a significant role in Helicobacter pylori immunological responses to. Four variants in β-defensins 1 and 2 genes (rs1800972 C/T, rs1047031 C/T, rs2740090 C/T and rs2740091 G/A) were included in a H. pylori patients in Iraq (80 Recurrent H. pylori infec...

Interleukin-17A (IL-17A) is pro-inflammatory cytokine that has been suggested to influence susceptibility to asthma. This study sought to explore serum level and three variants of IL17A gene (rs2275913 G/A, rs3819024 A/G and rs8193036 C/T) in Iraqi asthmatics to evaluate their association with susceptibility to disease. A case-control study was con...

Interleukin-33 is proposed to influence asthma susceptibility. Three IL33 gene variants (rs928413, rs16924159 and rs7037276) were included in a case-control study conducted on 104 Iraqi asthmatics and 111 controls. Tetra-primer-amplification-refractory-mutation-system-polymerase-chain-reaction method was used to determine these variants. Logistic r...