Sechang Oh

Sechang Oh
R Professional University of Rehabilitation · Faculty of Rehabilitation

PhD

About

50
Publications
9,313
Reads
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766
Citations
Citations since 2017
34 Research Items
658 Citations
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2017201820192020202120222023020406080100120140
2017201820192020202120222023020406080100120140
2017201820192020202120222023020406080100120140

Publications

Publications (50)
Article
Full-text available
Purpose: This population-based cross-sectional study aimed to determine whether the triglyceride–glucose index (TyG index) is associated with sarcopenic obesity (SO) and whether it would be a helpful indicator of SO. Methods: A total of 3821 participants aged ≥60 years were selected for the study group, and 4919 participants aged 20–39 years were i...
Article
Full-text available
The visceral adiposity index (VAI) was recently introduced to quantify visceral fat accumulation and dysfunction. This cross-sectional study explored whether the VAI is associated with chronic kidney disease (CKD) in older adults and compared its utility with that of body mass index (BMI) for predicting CKD. In total, 7736 older adults (3479 men an...
Poster
Full-text available
We performed a population-based cross-sectional study to determine whether the triglyceride-glucose index (TyG index) is associated with sarcopenic obesity (SO) and whether it would be a useful indicator of SO. Of the 37,753 participants in the Korea National Health and Nutritional Examination Survey (2008–2011), 3,821 men and women aged ≥60 years...
Article
Full-text available
A body shape index (ABSI) is a recently introduced index of abdominal adiposity, relative to body mass index and height, and represents an alternative to body mass index and waist circumference. We aimed to determine whether ABSI is associated with osteoporosis and the ability of ABSI to predict osteoporosis, to investigate the relationship between...
Article
Full-text available
The A Body Shape Index (ABSI) was recently introduced to quantify abdominal adiposity relative to the body mass index (BMI) and height. This cross-sectional study was performed to explore whether the ABSI is linked to chronic kidney disease (CKD) in older adults and compare the predictive capacity of the ABSI versus BMI for CKD. In total, 7053 peop...
Article
Full-text available
Objective: Excessive exercise increases the production of reactive oxygen species in skeletal muscles. Sulforaphane activates nuclear factor erythroid 2-related factor 2 (Nrf2) and induces a protective effect against oxidative stress. In a recent report, sulforaphane intake suppressed exercise-induced oxidative stress and muscle damage in mice. Ho...
Article
Full-text available
(1) Aim: Hepatic fibrosis is a prognostic factor for disease progression in non-alcoholic fatty liver disease (NAFLD). We aimed to determine the relationships between diet, physical activity, and the progression of liver fibrosis. (2) Methods: The 349 participants were categorized by their FibroScan-aspartate aminotransferase score, and they comple...
Article
Full-text available
Abstract Exercise ameliorates nonalcoholic fatty liver disease (NAFLD) by inducing phenotypic changes in Kupffer cells (KCs). p62/Sqstm1‐knockout (p62‐KO) mice develop NAFLD alongside hyperphagia‐induced obesity. We evaluated (1) the effects of long‐term exercise on the foreign‐body phagocytic capacity of KCs, their surface marker expression, and t...
Article
Full-text available
Exercise can be hypothesized to play an important role in non-alcoholic fatty liver disease (NAFLD) treatment by changing the oral bacterial flora and in the mechanism underlying periodontal disease. We performed salivary component analysis before and after an exercise regimen, and genome analysis of the oral bacterial flora to elucidate the underl...
Article
Full-text available
Background & Aims A weight loss-independent beneficial effect of exercise on non-alcoholic fatty liver disease (NAFLD) management has been reported, but the underlying mechanism is unknown. To help determine this mechanism, the effects of exercise on individual tissues (liver, adipose tissue, and skeletal muscle) were retrospectively studied. Meth...
Article
Full-text available
This cross-sectional pilot study aimed to assess the relationships of fat and muscle mass with chronic kidney disease (CKD) in older adults. Serum creatinine concentration was used to measure estimated glomerular filtration rate (mL/min/1.73 m 2) in the 236 subjects, who were allocated to three groups: a normal (≥60.0), a mild CKD (45.0-59.9), and...
Article
Full-text available
Background Several methods have been proposed to prevent post intensive care syndrome (PICS) after sepsis, including early mobilization, but controversy remains in mechanisms and outcomes. Therefore, the aim of this study is to establish a septic mouse model and classify exercise intensities during the acute phase of sepsis to generate a murine sep...
Article
Full-text available
Background: Maintaining a good level of physical fitness from engaging in regular exercise is important for the treatment and prevention of metabolic syndrome (MetS). However, which components constitutive of physical fitness confer the greatest influence remains controversial. This retrospective cross-sectional study aimed to investigate the asso...
Poster
Full-text available
Background. The purpose of this retrospective cross-sectional study was to investigate the association between MetS and physical fitness factors such as cardiorespiratory fitness, muscle strength, flexibility, and agility, and to identify which physical fitness factor has the largest effect on MetS. Methods. Subjects were 168 middle-aged men and we...
Preprint
Full-text available
Background: Several methods have been proposed to prevent post intensive care syndrome (PICS) after sepsis, including early mobilization, but controversy remains in mechanisms and outcomes. Translational studies are required to fully reveal the optimal exercise intensity during acute phase sepsis. The aim of this study is to establish a septic mous...
Article
Aim The underlying mechanism of non‐obese NAFLD has not been fully elucidated. We classified patients with NAFLD by sex and BMI and compared their clinical features to clarify the background pathophysiology of non‐obese NAFLD. Methods A total of 404 patients with NAFLD were divided according to their BMI (< 25 (non‐obese), 25 to < 30 (obese), and...
Article
Full-text available
Sarcopenia is a pathological condition affecting the development and progression of NAFLD. Urinary levels of titin-N fragment, a biomarker reflecting muscle damage, were measured in NAFLD subjects, and analyzed in a retrospective manner for possible correlations with NAFLD pathophysiology to assess their clinical relevance. This study enrolled 153...
Article
Full-text available
The purposes of this study were twofold: (a) to examine role of body mass index in incidence of low back pain and (b) to investigate more relevant causes of low back pain in body composition. Of the 250 initial subjects, 188 subjects were included for the first analysis and divided into quartiles based on the scores of Japan Low Back Pain Evaluatio...
Article
Full-text available
Physical exercise has demonstrated benefits for managing nonalcoholic fatty liver disease (NAFLD). However, in daily life maintaining exercise without help may be difficult. A whole‐body vibration device (WBV) has been recently introduced as an exercise modality that may be suitable for patients who have difficulty engaging in exercise. We tested W...
Article
Full-text available
Background: Deceased muscle mass combined with increased visceral fat mass is reportedly linked to a higher risk of worsening the hepatic conditions of non-alcoholic fatty liver disease (NAFLD). Objective: The aim of this study was conducted in a retrospective manner to investigate whether longitudinal changes in skeletal muscle mass to visceral fa...
Article
Full-text available
A novel notion has arisen in clinical medicine: non-alcoholic fatty liver disease (NAFLD), representing a spectrum of conditions ranging from asymptomatic simple steatosis to steatohepatitis and cirrhosis. Even though there is a pressing need to treat this disease, the treatment options are limited. Previous studies have confirmed that weight loss...
Article
Full-text available
Background and purpose Periodontal disease is closely related to lifestyle-related diseases and obesity. It is widely known that moderate exercise habits lead to improvement in lifestyle-related diseases and obesity. However, little research has been undertaken into how exercise habits affect periodontal disease. The purpose of this study was to ex...
Article
Full-text available
[Purpose] To date, there have been no reports on whether weight reduction causes decreases in muscle mass, muscle strength, or physical performance that could lead to health problems. Thus, in this pilot study, we investigated the appropriateness of the changes in muscle mass, muscle strength and physical performance after weight reduction. [Metho...
Article
Full-text available
Sulforaphane (SFN) plays an important role in preventing oxidative stress by activating the nuclear factor (erythroid derived 2)-like 2 (Nrf2) signalling pathway. SFN may improve exercise endurance capacity by counteracting oxidative stress-induced damage during exercise. We assessed running ability based on an exhaustive treadmill test (progressiv...
Article
Full-text available
The failure of Kupffer cells (KCs) to remove endotoxin is an important factor in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). In this study, the effects of exercise training on KC function were studied in terms of in vivo endotoxin clearance and inflammatory responses. Mice were allocated into rest and exercise groups. KC bead pha...
Article
Background: Not only obesity but also sarcopenia is associated with NAFLD. The influence of altered body composition on the pathophysiology of NAFLD has not been fully elucidated. The aim of this study is to determine whether skeletal muscle mass to visceral fat area ratio (SV ratio) affects NAFLD pathophysiology. Methods: A total of 472 subject...
Article
Full-text available
Background and objective: The benefits of weight reduction for musculoskeletal disorders are well understood. Steep declines in muscle mass following considerable weight reduction can decrease muscle strength and, consequently, physical performance. However, only a limited number of studies have examined the changes in muscle mass and strength in t...
Article
Full-text available
We compared the effects of 12-week programs of resistance training (RT), high-intensity interval aerobic training (HIAT), and moderate-intensity continuous aerobic training (MICT). The primary goal was to evaluate the therapeutic effects of the exercise modalities for the management of nonalcoholic fatty liver disease (NAFLD). A total of 61 sedenta...
Article
Full-text available
Regular physical exercise is central to a healthy lifestyle. However, exercise-related muscle contraction can induce reactive oxygen species and reactive nitrogen species (ROS/RNS) production in skeletal muscle. The nuclear factor-E2-related factor-2 (Nrf2) transcription factor is a cellular sensor for oxidative stress. Regulation of nuclear Nrf2 s...
Article
Full-text available
目的:超音波検査は脂肪肝の検出に優れたモダリティであるが,肝脂肪化を定量的に評価することは困難である.近年,Controlled Attenuation Parameter( CAP) を用いることで肝脂肪量の定量化が可能となった.今回は,非アルコール性脂肪性肝疾患( nonalcoholicfatty liver disease: NAFLD) の診断および治療におけるCAPの有用性について検討した. 対象と方法:対象は,診療ガイドライン( J Gastroenterol Hepatol 2007) にてNAFLDと診断した患者110名,対照者として肝疾患を有さない者28名の計138名とした.CAPはFibroScan 502にて測定した.CAP,血液生化学検査,体組成の測定値について対比...
Article
Full-text available
Exercise training is an effective therapy for nonalcoholic fatty liver disease (NAFLD). Hybrid training (HYB) of voluntary and electrical muscle contractions was developed to prevent disuse atrophy during space flight. HYB can be applied to obtain a strength training effect accompanying articular movement. In this pilot study, we aimed to investiga...
Article
Full-text available
Both westernization of diet and lifestyle habits and chronic inactivity have accelerated the obese population in Japan. Obesity is defined as being a condition in which the excessive energy is stored in the body as fat. Irrespective of organs and tissues, excessive fat accumulation impairs their structure and function, that is, ectopic adiposis. Th...
Article
Full-text available
While aerobic training is generally recommended as therapeutic exercise in guidelines, the effectiveness of resistance training has recently been reported in the management of nonalcoholic fatty liver disease (NAFLD). Acceleration training (AT) is a new training method that provides a physical stimulation effect on skeletal muscles by increasing gr...
Article
Unlabelled: Recently, the beneficial effects of increased physical activity (PA) on nonalcoholic fatty liver disease (NAFLD) in obese subjects were reported. However, the optimal strength and volume of PA in lifestyle modification to improve NAFLD pathophysiology and be recommended as an appropriate management of this condition are unclear. The pr...
Article
Full-text available
Background: Abdominal fat (AF) reduction is advocated in the treatment of obesity-related diseases. Nonetheless, recent studies have shown additional beneficial effects against obesity-related health risks, independent of AF reduction. Therefore it is important to determine whether AF plays a causal role in promoting metabolic disorders or is simp...
Article
Background: A diet regimen focusing on weight loss is still the most efficient treatment for nonalcoholic fatty liver disease (NAFLD). Recently, specific benefits of exercise against NAFLD independent of weight loss have been reported. Hence, combining exercise with diet-induced weight loss can be expected to have an additive benefit for NAFLD man...
Article
Full-text available
This study examines fermentative hydrogen production from untreated (raw) sludge and pretreated sludge by sterilization treatment (15, 30, 45, and 60 min) as substrate using mixed cultures in batch experiments under anaerobic thermophilic conditions. Longer treatment time was found to be highly effective for hydrolyzing organic matters in the sludg...
Conference Paper
This study investigates biohydrogen production from sewage sludge as substrate by mixed cultures using batch experiments under thermophilic anaerobic conditions and four different sterilization times (15, 30, 45, and 60 min). Increasing the sterilization time caused a decrease in the total solids (TS) and volatile solids (VS), however, the soluble...
Article
Purpose: Weight reduction remains the most common therapy advocated for the treatment of obesity-related liver diseases. Recently, a beneficial effect of exercise regimens for liver dysfunction, independent of weight reduction, has been reported. Therefore, a retrospective analysis was conducted to determine whether exercise training without dieta...
Article
Bioenergy produced from co-digestion of sewage sludge (SS) and rice straw (RS) as raw materials, without pretreatment and additional nutrients, was compared for the one-stage system for producing methane (CH4) and the two-stage system for combined production of hydrogen (H2) and CH4 in batch experiments under thermophilic conditions. In the first s...
Article
Full-text available
The purpose of this study was to investigate by meta analysis in collecting research references whether exercise intervention affects bone density in domestic studies. Collecting total 22 references(60 researches) showed below results. A bone density variation of Femur neck appeared as EStotal (Total Effect Size) = 0.12 from total 27 researches, an...

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