Sebati Sinan Ürkmez

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Verified

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• PhD
• Research Assistant at Ondokuz Mayıs University

Neuroinflammation and the immune response are recognized as significant mechanisms contributing to the progression and pathophysiology of Parkinson’s disease (PD). Consequently, extensive research is being conducted on drugs targeting inflammation and immune response. Leflunomide, known for its anti‑inflammatory and immunomodulatory properties, is...

This study aims to evaluate the efficacy of maternal hemogram parameters in PPH in term pregnancies. A retrospective analysis was conducted on 84 patients with atony-related PPH and 96 control patients with healthy deliveries, who presented to the Gynecology and Obstetrics Clinic of Samsun Education and Research Hospital between January 1, 2008, an...

Objective To review the outcomes of in vitro maturation (IVM) and in vitro fertilization (IVF) in women with empty follicle syndrome (EFS). The study evaluated the genetic underpinnings of EFS by analyzing mutations. Materials and Methods This retrospective case series involving 17 women with EFS over at least 2 IVF cycles was conducted. The study...

Objectives The safety of cesarean myomectomy has been proven by previous studies. Our study aimed to reveal the long-term perinatal, obstetric, and surgical outcomes of cesarean myomectomy (CM) by comparing different CM techniques. Material and methods This retrospective multicentric case–control study involved 7 hospitals and included 226 singlet...

Objective: This study aims to investigate the developmental potential of immature oocytes and questions whether unstimulated in vitro maturation (IVM) can be used as a treatment in women with oocyte maturation abnormalities. Material and methods: This cohort study was conducted between September 2019 and December 2022, and it included 12 women w...

Breast cancer represents the most prevalent cancer type among women globally. Accurate molecular subtyping of breast cancer plays a vital role in determining optimal treatment strategies. Therefore, the main objective of this observational study is to investigate the correlation between breast cancer and its molecular subtypes with ribosomal protei...

Effects of pre/postnatal 2.45 GHz continuous wave (CW), Wireless-Fidelity (Wi-Fi) Microwave (MW) irradiation on bone have yet to be well defined. The present study used biochemical and histological methods to investigate effects on bone formation and resorption in the serum and the tibia bone tissues of growing rats exposed to MW irradiation during...

In our study, we aimed to create an inflammation model in endothelial and macrophage cell lines and to examine the changes in the expression of hyperpolarization activated cyclic nucleotide gated (HCN) channels at the molecular level. HUVEC and RAW cell lines were used in our study. 1 µg/mL LPS was applied to the cells. Cell media were taken 6 h la...

The translation process consists of translation factors and ribosomes. Ribosomal components include ribosomal proteins (RP) and ribosomal RNA. Many RPs are involved in assembling ribosomal particles and or stabilizing important regions of rRNA. Besides their conventional roles, RPs have been reported to exhibit secondary functions that have not yet...

Approximately 5% of transmissible venereal tumour can metastatize to various parts of the body. The case presented explains the clinical appearance and histopathology results of the ovarian metastasis of TVT in a female German shepherd. The bitch was brought to the teaching hospital of Ondokuz Mayıs University, Faculty of Veterinary Medicine with a...

Objective and background How smoking affects periodontal inflammation and healing still needs to be revealed with all its mechanisms. In this study, the gingival crevicular fluid (GCF) levels of: (a) interleukin‐17A (IL‐17A) and interleukin‐17E(IL‐17E) with their ratios and (b) oxidative stress by means of total oxidative stress (TOS), total anti‐o...

Objectives: This study aims to investigate the relationship between serum level of nesfatin-1 and fibromyalgia syndrome (FMS) clinical parameters such as pain severity, disease activity, fatigue, emotional state, and sleep quality. Patients and methods: Forty-six female patients with FMS (median age 40 years; range, 18 to 53 years) and 46 health...

Son yıllarda birçok proteinin birden fazla fonksiyona sahip olduğu bilgisi, bir gen - bir protein - bir fonksiyon fikrinin yerini almaya başlamıştır. Moonlight proteinler çok fonksiyonlu proteinlerin bir alt sınıfıdır. Moonlight protein kavramı, tek bir polipeptid zincirinin çoklu biyokimyasal fonksiyonları yerine getirmesini tanımlamaktadır. Bugün...

ICATES 2019 provides an ideal academic platform for researchers to present the latest research findings and describe emerging technologies, and directions in Engineering and Natural Sciences issues. The conference seeks to contribute to presenting novel research results in all aspects of Engineering, Technology and Natural Sciences. The conference...

Background Fibromyalgia (FM) is characterised by chronic widespread pain, sleep disturbances, affective disorders, fatigue, cognitive dysfunction, anxiety and depressive episodes and its pathogenesis is still unclear.¹ Nesfatin-1 is a recently identified anorexigenic hypothalamic polypeptide which plays role on mood, stress, sleep, anxiety, eating...