
Sebastian NemethUniversity of Oradea · Department of Pharmacy
Sebastian Nemeth
Professor, PhD., MEd, BPharm.
About
31
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Introduction
Sebastian Nemeth currently works at the Department of Pharmacy, University of Oradea. Sebastian does research in Pharmacy.
Education
October 2003 - November 2009
October 1998 - September 2003
Publications
Publications (31)
Our study compares the content in polyphenolic compounds and hypericin, in four species of Hypericum - H. perforatum L., H. maculatum Cr., H. hirsutum L., H. tetrapterum Fr. (syn. Hypericumacutum Mnch.) harvested from spontaneous flora in the north-western area of Transylvania, Romania. These species represent an important source of such compounds...
Coffea species are well known and grown in almost all countries in the Equatorial region. Many Coffee species
have a long standing history and they play a significant role in the world market and in pharmacological studies
nowadays. Due to the rich caffeine and phenolic compounds content of seeds, they have a successful utilization
in food, cosmeti...
Four Salvia officinalis L. populations were examined for the extent of genetic variability and compared with S. judaica Boiss., by extracting genomic DNA and generating a random amplified polymorphic DNA (RAPD) marker profile. Hierarchical cluster analysis separated the common sage populations into two groups. The two Hungarian S. officinalis L. sa...
The „H-PASS” project, operating across 6 EU Member States, including Romania, aims to enhance healthcare workforce competencies amidst digital transformation. It proposes a comprehensive training program targeting diverse healthcare profes- sionals, focusing on transversal skills and digital literacy. By leveraging innovative methods like virtual r...
While it has been seen as a disease with a positive prognosis in the past, currently rheumatoid arthritis (RA) is labelled as a debilitating, progressive disease that causes substantial and crippling osteoarticular damage linked to increased premature mortality. Remission is increasingly faced with queries about the effective management of therapy...
While it has been seen as a disease with a positive prognosis in the past, currently rheumatoid arthritis (RA) is labelled as a debilitating, progressive disease that causes substantial and crippling osteoarticular damage linked to increased premature mortality. Remission is increasingly faced with queries about the effective management of therapy...
The assessment of magnesium orotate compatibility with various excipients is an important step in the development of drug
formulation and development. A good physicochemical compatibility between magnesium orotate and different excipients
allows obtaining novel combinations with a complex composition that enhances the therapeutic effect of magnesiu...
This is my Habilitation thesis, in order to have the right to coordinate PhD students.
The purpose of this research was to assess the correlation between glycemic control and clinical periodontal characteristics in type 2 diabetics with generalized chronic periodontitis. A total of 182 patients with type 2 diabetes mellitus and generalized chronic periodontitis were included in our study. The clinical examination included full-mouth...
Osteoporosis, a major skeletal disorder characterized by decreased bone mass, predominantly affects women and has a major impact on public health. Fractures due to bone fragility are the most important complications of osteoporosis. The main objectives of the optimal management of osteoporosis are to increase muscle strength and strengthen bones, r...
(1) The metabolic syndrome (MS) promotes acute and chronic infections, due to the pro-inflammatory condition given by TNFα and IL6 or by affecting the microbiota. MS is also correlated with insulin resistance, causing inflammation and infections throughout the organism. (2) The purpose of this study was to track the effect of using the essential oi...
Non-alcoholic fatty liver disease (NAFLD) is a component of metabolic syndrome that significantly increases the cardiovascular risk of patients with glucose metabolism alterations. This study identified the prevalence of NAFLD, predictors of NAFLD and explored the link between insulin sensitivity, insulin resistance and leptinemia in 143 patients r...
For a long time, algal chemistry from terrestrial to marine or freshwater bodies, especially chlorophytes, has fascinated numerous investigators to develop new drugs in the nutraceutical and pharmaceutical industries. As such, chlorophytes comprise a diverse structural class of secondary metabolites, having functional groups that are specific to a...
A sensitive electrochemical method was used for the determination of the total phenolic content and antioxidant activity of Echinacea purpurea extracts. In this study, 3 glassy carbon electrodes (GCE) were used: one unmodified and the other two newly manufactured glassy carbon electrodes modified with carbon nanotubes (CNTs) and chitosan (CS) in di...
Chamomile is a highly appreciated plant due to a whole range of therapeutic characteristics
providing numerous benefits for the human body and being well accepted both by human body organs
and systems, and skin. The purpose of this research is the chemical determination and studying the
antimicrobial activity of the essential oil obtained from the...
Obesity and overweight are major contributors to the morbidity and mortality of modern civilization. This study determined the prevalence of certain risk factors for adiposity and assesses their impact on overweight/obesity prevalence. Nine hundred individuals were evaluated, aged between 18-65 years, including clinical examination, evaluation of m...
The almond nuts are an important source of unsaturated fats that may contribute to a significant decreasing of cholesterol level in blood. Six patented almond varieties grown in North-Western part of Romania, Bihor County (Sort A, Sort B, Sort C, Sort D, Sort E, and Sort F) were selected in order to determine the fatty acid composition and the anti...
In the present study we investigated the effects of chronic oral treatment with fenugreek seeds (Trigonella foenum-graecum, TFG) and diosgenin (DG), one of its saponins, on diet induced obese (DIO) rats. Under the six weeks long treatment period metabolic parameters such as body weight, food and water intake were daily measured. At the end of the 6...
In type 2 diabetes mellitus (DM) patients, hepatic steatosis is present in a much higher proportion than in healthy people. In this study, we have evaluated the presence of steatosis in patients with type 2 DM, and whether this may be correlated with the type of treatment that patients are using, either with oral antidiabetics (OAD), or with insuli...
Chemistry in agriculture has been considered for several decades a formula synonymous with progress and development, as chemical engineering, mechanization, irrigation, modern agro-technical processes have contributed to a substantial increase in production. At present, the use of pesticides to increase agricultural productivity is considered to be...
We determined the total phenolic content and the antioxidant activity of hydro-alcoholic extracts obtained from waste materials resulted in the essential oil extraction process during thyme and oregano distillation. All extracts have shown high antioxidant activity that ranged between 18 to 47 mg (gallic acid equivalent) GAE/L, 1.4 to 4 mmol (Trolo...
Pain is a global phenomenon which involves two essential and distinct aspects: perception and response to pain. NSAIDs inhibit the formation of prostaglandins which are proinflammatory mediators by inhibiting nonselective cyclooxygenase enzymes both COX1 and COX2 which have a role in propagating that pain and platelet adhesion. It turned out that a...
This paper presents a series of researches conducted on two species belonging to the Equisetum genus, Equisetum arvense L. and Equisetum telmateia Ehrh., by establishing the amount of flavonoids, phenolic acids, antioxidant capacity and histo-anatomical characters. In the Romanian Pharmacopoeia 10 th edition and in the European Pharmacopoeia (Ph. E...
Abstract:
Objective: To investigate the antioxidant activity, total phenolic and total tannin content of the pericarp and the seed of Coffea benghalensis and C. liberica compared to C. arabica.
Methods: The antioxidant potential, total tannin and polyphenol contents of the immature and mature seed and pericarp of Coffea benghalensis and C. liberic...
Even if the modern man prefers food products with optimum nutrient content, with superior sensory properties, obtained by technologies that do not affect the nutritional value of the nutrients, however, the consumption of foods rich in acrylamide is increasing as fast-food type of products are preferred, products created to excite the taste buds. A...
Angelica archangelica L. has traditionally been used and appreciated for centuries. There is ample data to suggest the potent properties of this plant and its compounds, which have been used to explain most of its observed biological activities. The purpose of this study was to highlight the TLC method of coumarins, a MeOH extract from the bark of...
Coffea benghalensis B. Heyne ex Schult. as a wild Indian coffee species, has been rarely studied and applied in the industry nowadays. In this work, histological characters of the leaf and petiole, and polyphenolic compounds of the leaf, immature pericarp and seed were studied by LC/MS, and compared with C. arabica as a control species. The epiderm...