Sean Peterson

Sean Peterson
University of Waterloo | UWaterloo · Department of Mechanical and Mechatronics Engineering

Ph.D.

About

164
Publications
19,599
Reads
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1,830
Citations
Citations since 2017
81 Research Items
1116 Citations
2017201820192020202120222023050100150200250
2017201820192020202120222023050100150200250
2017201820192020202120222023050100150200250
2017201820192020202120222023050100150200250
Introduction
Additional affiliations
June 2009 - June 2015
University of Waterloo
Position
  • Professor (Assistant)
January 2007 - present
Polytechnic Institute of New York University
Position
  • Affiliated Faculty

Publications

Publications (164)
Article
Full-text available
Grouping the thin epithelium and thicker superficial lamina propria layers into a single cover layer has been widely adopted in finite element vocal fold models. Recent silicone vocal fold studies have suggested, however, that inclusion of a distinct epithelial layer leads to more physiologically representative motion. This study systematically exp...
Article
Full-text available
Fundamental frequency patterns during phonation onset have received renewed interest due to their promising application in objective classification of normal and pathological voices. However, the associated underlying mechanisms producing the wide array of patterns observed in different phonetic contexts are not yet fully understood. Herein, we emp...
Article
Objectives Relative fundamental frequency (RFF) is an acoustic measure of changes in fundamental frequency during voicing transitions. The physiological mechanisms underlying RFF remain unclear. Recent modeling suggests that changes in RFF during voicing offset are due to decreases in overall system stiffness as a direct result of the cessation of...
Article
Elucidating the hydrodynamics of fish swimming is critical to identifying the processes underlying fish orientation and schooling. Due to their mathematical tractability, models based on potential flow are preferred in the study of bidirectional interactions of fish with their surroundings. Dipole-based models that assimilate fish to pairs of vorti...
Article
Objective: To develop and evaluate an accurate method for cuffless blood pressure (BP) estimation during moderate- and heavy-intensity exercise. Methods: Twelve participants performed three cycling exercises: a ramp-incremental exercise to exhaustion, and moderate and heavy pseudorandom binary sequence exercises on an electronically braked cycle...
Article
The aerodynamics of finite-span inclined flat plates in ground effect is experimentally investigated at a chord-based Reynolds number of 50 000 for aspect ratios of 1 and 2. The minimum ground height is varied between 0.1 and 1.0 chord lengths, and lift and drag forces are measured using a force balance for angles of attack between −90° and 90°. Pl...
Article
Full-text available
Purpose The goal of this study was to experimentally evaluate how compensating for the adverse acoustic effects of a posterior glottal opening (PGO) by increasing subglottal pressure and changing supraglottal compression, as have been associated with vocal hyperfunction, influences the risk of vocal fold (VF) trauma. Method A self-oscillating synt...
Article
Full-text available
For over a century, scientists have sought to understand how fish orient against an incoming flow, even without visual and flow cues. Here, we elucidate a potential hydrodynamic mechanism of rheotaxis through the study of the bidirectional coupling between fish and the surrounding fluid. By modeling a fish as a vortex dipole in an infinite channel...
Article
Full-text available
A substantial barrier to the clinical adoption of cuffless blood pressure (BP) monitoring techniques is the lack of unified error standards and methods of estimating measurement uncertainty. This study proposes a fusion approach to improve accuracy and estimate prediction interval (PI) as a proxy for uncertainty for cuffless blood BP monitoring. BP...
Article
In an effort to mitigate the 2019 novel coronavirus disease pandemic, mask wearing and social distancing have become standard practices. While effective in fighting the spread of the virus, these protective measures have been shown to deteriorate speech perception and sound intensity, which necessitates speaking louder to compensate. The goal of th...
Article
Poor laryngeal muscle coordination that results in abnormal glottal posturing is believed to be a primary etiologic factor in common voice disorders such as non-phonotraumatic vocal hyperfunction. Abnormal activity of antagonistic laryngeal muscles is hypothesized to play a key role in the alteration of normal vocal fold biomechanics that results i...
Preprint
Full-text available
For over a century, scientists have sought to understand how fish orient against an incoming flow, even without visual and flow cues. Here, we make an essential step to elucidate the hydrodynamic underpinnings of rheotaxis through the study of the bidirectional coupling between fish and the surrounding fluid. By modeling a fish as a vortex dipole i...
Article
Background Chemotherapy-induced peripheral neuropathy, a side effect of cancer treatment, presents several issues to patients, including reduced sensation and increased fall risk. Previously, massage therapy has been shown to improve chemotherapy-induced peripheral neuropathy symptoms, possibly through increased blood flow. A custom built intermitt...
Article
We revisit the mechanism of viscous vortex reconnection by considering the collision of vortex rings over a range of initial collision angles and Reynolds numbers. While the overall reconnection process is similar to anti-parallel vortex reconnection, we find that collision angle exerts significant influence over the process, altering the evolution...
Preprint
Full-text available
Poor laryngeal muscle coordination that results in abnormal glottal posturing is believed to be a primary etiologic factor in common voice disorders such as non-phonotraumatic vocal hyperfunction. An imbalance in the activity of antagonistic laryngeal muscles is hypothesized to play a key role in the alteration of normal vocal fold biomechanics tha...
Article
Full-text available
Self-sustained oscillations of the vocal folds (VFs) during phonation are the result of the energy exchange between the airflow and VF tissue. Understanding this mechanism requires accurate investigation of the aerodynamic pressures acting on the VF surface during oscillation. A self-oscillating silicone VF model was used in a hemilaryngeal flow fa...
Article
Full-text available
The ongoing COVID-19 pandemic has highlighted the importance of aerosol dispersion in disease transmission in indoor environments. The present study experimentally investigates the dispersion and build-up of an exhaled aerosol modeled with polydisperse microscopic particles (approximately 1 lm mean diameter) by a seated manikin in a relatively larg...
Article
Full-text available
The energy dissipated during vocal fold (VF) contact is a predictor of phonotrauma. Difficulty measuring contact pressure has forced prior energy dissipation estimates to rely upon generalized approximations of the contact dynamics. To address this shortcoming, contact pressure was measured in a self-oscillating synthetic VF model with high spatiot...
Article
Relative fundamental frequency (RFF) is a promising assessment technique for vocal pathologies. Herein, we explore the underlying laryngeal factors dictating RFF behaviours during phonation offset. To gain physical insights, we analyze a simple impact oscillator model and follow that with a numerical study using the well-established body-cover mode...
Article
The dynamics of a cantilevered plate driven by a train of tangentially-advecting vortex rings is significantly impacted by two temporal parameters, namely the Strouhal number and the frequency ratio. The former relates the vortex ring advection time-scale to the fundamental period of the vibrating structure, while the latter relates the vortex prod...
Article
Flow development over isolated, surface-mounted, droplet-inspired three-dimensional obstacles submerged in a laminar boundary layer is investigated at a Reynolds number based on obstacle height of Reh=2070 using particle image velocimetry. Three geometries are considered, a sessile droplet; a droplet on the verge of runback (depinning); and a spher...
Article
Full-text available
Recently, Bayesian estimation coupled with finite element modeling has been demonstrated as a viable tool for estimating vocal fold material properties from kinematic information obtained via high-speed video recordings. In this article, the sensitivity of the parameter estimations to the employed fluid model is explored by considering Bernoulli an...
Article
Full-text available
Purpose Orthostatic hypotension, leading to cerebral hypoperfusion, can result in postural instability and falls in older adults. We determined the efficacy of a novel, intermittent pneumatic compression system, applying pressure around the lower legs, as a countermeasure against orthostatic stress in older adults. Methods Data were collected from...
Article
The objective is to develop a cuffless method that accurately estimates blood pressure (BP) during activities of daily living. User-specific nonlinear autoregressive models with exogenous inputs (NARX) are implemented using artificial neural networks to estimate the BP waveforms from electrocardiography and photoplethysmography signals. To broaden...
Data
The purpose of this data collection was for the validation of a cuffless blood pressure estimation model during activities of daily living. Data were collected on five young healthy individuals (four males, age 28 ± 6.6 yrs) of varied fitness levels, ranging from sedentary to regularly active, and free of cardiovascular and peripheral vascular dise...
Preprint
Full-text available
Self-sustained oscillations of the vocal folds during phonation are the result of the energy exchange between the airflow and the vocal fold tissue. Understanding this mechanism requires accurate investigation of the aerodynamic pressures acting on the vocal fold surface during oscillation. A self-oscillating silicone vocal fold model was used in a...
Article
Hot environmental conditions can challenge thermoregulation resulting in exacerbated heat strain. This study evaluated the influence of continuous inner forearm cooling on gastrointestinal temperature (T GI) and physiological responses to exercise in hot (30°C) and humid (relative humidity: 70%) conditions. Eleven trained cyclists (seven male age:...
Conference Paper
Full-text available
Abstract: Herein we compare the drag-area estimated using unsteady Reynolds-averaged Navier-Stokes (URANS) using the γ−ReΘ transitional SST k−ω (SSTLM) turbulence model with published experimental measurements of a static full-scale cyclist mannequin in an open test-section wind tunnel with the left leg fully extended. The turbulence model employs...
Conference Paper
Full-text available
This work presents a modelling approach to predict the blood pressure (BP) waveform time series during activities of daily living without the use of a traditional pressure cuff. A nonlinear autoregressive model with exogenous inputs (NARX) is implemented using artificial neural networks and trained to predict the BP waveform time series from electr...
Article
Full-text available
Herein, we compare the drag area estimated using unsteady Reynolds-averaged Navier-Stokes (URANS), using the γ−ReΘ transitional shear stress transport (SST) k−ω (SSTLM) turbulence model with published experimental measurements of a static full-scale cyclist mannequin in an open test section wind tunnel, with the left leg fully extended. The turbule...
Article
Full-text available
This study introduces the in vivo application of a Bayesian framework to estimate subglottal pressure, laryngeal muscle activation, and vocal fold contact pressure from calibrated transnasal high-speed videoendoscopy and oral airflow data. A subject-specific, lumped-element vocal fold model is estimated using an extended Kalman filter and two obser...
Article
The effect of Reynolds number on the flow development upstream of a rigid, non-porous, static fence is investigated experimentally. The flow field is measured using time-resolved, two-component particle image velocimetry at Reynolds numbers based on fence height of 18000, 36000, and 54000. The results show that a laminar separation bubble forms ups...
Article
Full-text available
A finite element approach for calculating pressure fields from planar velocity data is examined in this paper and compared with widely cited procedures. In the current approach, the order of velocity derivatives in the source function is reduced via a finite element procedure where the pressure Poisson equation is solved. This method benefits from...
Article
Full-text available
The objective is to develop a cuffless modelling approach to accurately estimate the blood pressure (BP) waveform and extract important BP features, such as the systolic BP (SBP), diastolic BP (DBP), and mean BP (MAP). Access to the full waveform has significant advantages over previous cuffless BP estimation tools in terms of accuracy and access t...
Article
Full-text available
A critical element in understanding voice production mechanisms is the characterization of vocal fold collision, which is widely considered a primary etiological factor in the development of common phonotraumatic lesions such as nodules and polyps. This paper describes the development of a transoral, dual-sensor intraglottal/subglottal pressure pro...
Conference Paper
This work presents a modelling approach to accurately predict the blood pressure (BP) waveform time series from a single input signal. A nonlinear autoregressive model with exogenous input (NARX) is implemented using artificial neural networks and trained on Electrocardiography (ECG) signals to predict the BP waveform. The efficacy of the model is...
Article
New findings: What is the central question of this study? Does smartly-timed intermittent compression of the lower legs alter cerebral blood velocity and oxygenation during acute orthostatic challenges? What is the main finding and its importance? Intermitted compression timed to the local diastolic phase increased the blood flux through the legs...
Conference Paper
Full-text available
Flow development over isolated surface-mounted, 3D obstacles submerged in a laminar boundary layer is investigated at a Reynolds number based on height of Re h = 2070 using Particle Image Velocimetry (PIV). The three geome-tries considered are inspired by morphological configurations of droplets deposited on a flat surface in a crossflow. The mean...
Article
Bayesian inference has been previously demonstrated as a viable inverse analysis tool for estimating subject-specific reduced-order model parameters and uncertainties. However, previous studies have relied upon simulated glottal area waveforms with superimposed random noise as the measurement. In practice, high-speed videoendoscopy is used to measu...
Article
Full-text available
Excessive vocal fold collision pressures during phonation are considered to play a primary role in the formation of benign vocal fold lesions, such as nodules. The ability to accurately and reliably acquire intraglottal pressure has the potential to provide unique insights into the pathophysiology of phonotrauma. Difficulties arise, however, in dir...
Article
Full-text available
The complex three-way interaction between airflow, tissue, and sound, for asymmetric vocal fold vibration, is not well understood. Current modeling efforts are not able to explain clinical observations where drastic differences in sound production are often observed, with no noticeable differences in the vocal fold kinematics. To advance this under...
Article
Full-text available
Bayesian estimation has been previously demonstrated as a viable method for developing subject-specific vocal fold models from observations of the glottal area waveform. These prior efforts, however, have been restricted to lumped-element fitting models and synthetic observation data. The indirect relationship between the lumped-element parameters...
Article
The purpose of this study was to determine if muscle blood flow during walking exercise and post-exercise recovery can be augmented through the application of intermittent compression of the lower legs applied during the diastolic phase of the cardiac cycle. Results from four conditions were assessed: no compression (NoComp), compression during wal...
Article
Full-text available
The development of trauma-induced lesions of the vocal folds (VFs) has been linked to a high collision pressure on the VF surface. However, there are no direct methods for the clinical assessment of VF collision, thus limiting the objective assessment of these disorders. In this study, we develop a video processing technique to directly quantify th...
Conference Paper
Cooling treatment is important to ensure the survival of patients with Exertional Heat Stroke(EHS); however, the protective mechanism of aquaporins in the cooling treatment of EHS is not very clear. Cooling treatment induces changes in renal aquaporins and regulates homeostasis of water metabolism,which mechanism involves aquaporin gene expression....
Article
Full-text available
The flow development of a jet issued from a high-aspect ratio slot nozzle impinging on a flat plate is investigated experimentally. Time-resolved, two-component particle image velocimetry is used to characterize the flow for Reynolds numbers based on slot width and streamwise jet centerline velocity of 3000 and 6000, and impingement height ratios o...
Article
Swimming in schools affords several advantages for fish, including enhanced ability to escape from predators, searching for food, and finding correct migratory routes. However, the role of hydrodynamics in coordinated swimming is still not fully understood due to a lack of data-driven approaches to disentangle causes from effects. In an effort to e...
Article
Full-text available
The development of normal and oblique impinging slot jets is investigated experimentally using planar particle image velocimetry. The study is performed for two jet Reynolds numbers, \({Re} = 3000\) and 6000, and four jet orientation angles relative to the wall (\(\theta = 90^\circ , 60^\circ , 45^\circ , 30^\circ\)), with the nozzle-to-plate spaci...
Article
New findings: What is the central question of this study? Pulse contour analysis of the finger arterial pressure by Windkessel modelling is commonly used to estimate stroke volume continuously. But is it valid during dynamic changes in blood pressure? What is the main finding and its importance? Second-by-second analysis revealed that pulse contou...
Article
Particle image velocimetry (PIV) and digital image correlation (DIC) are widely used experimental techniques in fluid mechanics and structural dynamics, respectively. PIV is capable of resolving detailed velocity fields around structures, from which the hydrodynamic loading can be reconstructed. However, PIV is ill-suited to capturing the structura...
Article
Bayesian inference has recently been demonstrated to be effective in estimating stationary and non-stationary reduced-order vocal fold model parameters, along with the associated levels of uncertainty, from simulated glottal area waveform measures (Hadwin et al., 2016, 2017). In these studies, the fitting model was a three mass body-cover model wit...
Article
The interaction of a vortex ring impinging on a rigid wall with a coaxial aperture is examined experimentally with various aperture sizes and vortex ring Reynolds numbers. Flow visualization and particle image velocimetry are utilized to investigate the dynamics of the impact interaction. For large aperture-to–ring radius ratios, the vortex ring pa...
Article
The question of causality is pervasive to fluid–structure interactions, where it finds its most alluring instance in the study of fish swimming in coordination. How and why fish align their bodies, synchronize their motion, and position in crystallized formations are yet to be fully understood. Here, we posit a model-free approach to infer causalit...
Article
Flow-induced vibrations of flexible surfaces driven by coherent vortical structures are ubiquitous in engineering and biological flows; from the extraction of fluidic energy via oscillating electro-active polymers to vocal fold dynamics during voiced speech production. These scenarios may involve either discrete or periodic loading conditions due t...
Article
We describe a general algorithm for the construction of networks of tubes which occupy a specified, and possibly quite complicated, region D⊂R³ as fully as possible. Such networks can be important in a variety of industrial applications ranging from heat exchangers to storage vessels. The algorithm is comprised of three fundamental steps: (i) decom...
Article
Full-text available
Advances in additive manufacturing have enabled industry to relax many design constraints imposed by traditional construction methods. As such, it is now possible to design and build objects or devices with complex internal structures that conform to irregular external envelopes. In applications where fluid distribution or storage is an integral pa...
Article
Full-text available
Particle image velocimetry (PIV) is an experimental technique that uses microscale particles as tracers to measure the velocity of a fluid flow. In this paper, we seek to extend this technique to simultaneously measure fluid temperature as well, by employing a novel class of thermosensitive polymer particles. Towards this aim, we designed a process...
Article
This study tested the hypothesis that intermittent compression of the lower limb would increase blood flow during exercise and post-exercise recovery. Data were collected from 12 healthy individuals (8 men) who performed three minutes of standing plantar flexion exercise. Three conditions were tested: no applied compression (NoComp), compression du...
Article
The extraction of energy from vortical structures advecting through an ambient environment is a topic of interest due to the potential to power miniature in situ sensors and monitors. This work investigates the vortex dynamics and flow-induced vibrations of a flexible plate arising from a vortex ring passing tangentially over it. Experimental measu...
Article
Full-text available
The interest in the development of non-contact temperature sensors for particle image velocimetry (PIV) is continuously growing. The integration of thermochromic tracers in PIV represents a critical step forward in experimental fluid mechanics, which would enable detailed full-field analysis of thermal and environmental flows. In this paper, interp...
Article
Large-scale power generation and delivery to remote locales is often prohibitively expensive, due in part to the excessive costs of delivering the materials required to build the necessary infrastructure. In addition, these facilities can have deleterious effects on the local ecosystem. With their reduced physical and environmental footprints, smal...
Article
Purpose: Our goal was to test prevailing assumptions about the underlying biomechanical and aeroacoustic mechanisms associated with phonotraumatic lesions of the vocal folds using a numerical lumped-element model of voice production. Method: A numerical model with a triangular glottis, posterior glottal opening, and arytenoid posturing is propos...