Sean McNabney

• Master of Science
• Graduate Researcher at Indiana University Bloomington

Introduction: Obesity is a major health concern in the United States and many developed countries. Among its many deleterious effects are those that can affect the sexual response. Aim: To update and evaluate the state of knowledge on the possible link between obesity and sexual dysfunction. Methods: A comprehensive search and review of biomed...

Increased dietary fiber consumption has been associated with many beneficial effects, including amelioration of obesity and insulin resistance. These effects may be due to the increased production of short chain fatty acids, including propionate, acetate and butyrate, during fermentation of the dietary fiber in the colon. Indeed, oral and dietary s...

Masturbation, as a significant sexual activity within its own right, has garnered substantial interest as a research topic only within the past 10–20 years. In this in-depth analysis of masturbation in women, we examined relationships among frequencies of, reasons for, and activities during masturbation, and investigated how such parameters predict...

The effect of pornography on sexual response is understudied, particularly among women. A multinational, community-based sample of 2433 women at least 18 years of age completed a 42-item, opt-in questionnaire collecting information on demographic and sexual history characteristics, use of pornography during masturbation, frequency of pornography us...

Objectives: To evaluate whether the presence of sexual problems in men (i.e., erectile dysfunction, premature ejaculation, or delayed ejaculation) is associated with differential sexual behavior during masturbation and partnered sex. Methods: Cisgender participants (n = 2,807) completed an internet-based, cross-sectional questionnaire about sexu...

Purpose of review: Sexual dysfunction is commonly associated with overweight/obesity, but the underlying physiological and psychosocial mechanisms are not fully understood. This review contextualizes the obesity-sexual (dys)function relationship, describes recent insights from the medical and social science literature, and suggests opportunities f...

Men with delayed ejaculation are often categorized into lifelong and acquired subtypes, yet little is known about similarities and differences between these groups. In this study, we examined whether delayed ejaculation subtypes differed on various demographic, diagnostic, relationship, and sexual activity/satisfaction variables. We drew 140 men re...

The lack of empirically based diagnostic criteria for delayed ejaculation (DE) not only undermines confidence in the reported prevalence rates for this sexual dysfunction, but it has also resulted in a lack of validated patient reported outcomes (PROs) for assessing this condition. The current study was designed to describe and evaluate six face-va...

Introduction The role of bother/distress in the diagnosis of premature ejaculation (PE) has received minimal investigation compared with the 2 other diagnostic criteria, ejaculatory control and ejaculatory latency (EL). Aim This study assessed (i) the added variance explained by bother/distress to the diagnostic accuracy of PE and (ii) determined...

Introduction The criteria for premature ejaculation (PE) have generally been limited to the diagnosis of heterosexual men engaging in penile-vaginal intercourse and therefore the applicability of PE diagnostic criteria to gay men and to activities beyond penile-vaginal intercourse has yet to be explored in depth. Aim To compare the prevalence of P...

With approximately two-thirds of the United States adult population classified as overweight or obese, obesity remains a critical public health concern. Obesity not only contributes to several health complications including type 2 diabetes mellitus and cardiovascular disease, but the condition is also associated with sexual dysfunction in both wome...

Objective To investigate how orgasmic difficulty may impact women’s sexual/relationship quality depending upon their cultural origin. Method: We used a cross-sectional, multinational survey designed to assess orgasmic difficulty during partnered sex and other sexual/relationship factors in 88 Pakistani and 188 U.S. women. Results: Pakistani women r...

Purpose of Review In this review, we summarize recent empirical evidence assessing the relationship between nutrition and female sexual dysfunction and give a broad interpretation of the effects. Recent Findings Dietary patterns that ensure adequate intake of shortfall nutrients may help to ameliorate reproductive problems associated with eating d...

Purpose of Review In this update on plant-derived supplements, we provide a general introduction regarding the status and interest in phytochemicals for sexual health, indicating both progress and problems with past and current research. Recent Findings We summarize the development and current status of two well-known plant-derived supplements, us...

Purpose of Review In this review, we revisit and evaluate empirical research on six herbal supplements purported to affect sexual and/or reproductive function in men and women. Recent Findings We summarize and critically review recent evidence—both human and non-human—supporting the role of six commonly cited herbs on men’s and women’s sexual heal...

Dietary supplementation with the short chain fatty acid butyrate prevents obesity and insulin resistance in mice fed a high fat diet (HFD). Unfortunately, the translational potential of dietary butyrate supplementation is limited due to its teratogenic effects at higher doses. More recently, attention has turned to resistant starches that produce b...

Skeletal muscle mitochondrial dysfunction, evidenced by incomplete beta oxidation and accumulation of fatty acid intermediates in the form of long and medium chain acylcarnitines, may contribute to ectopic lipid deposition and insulin resistance during high fat diet (HFD)-induced obesity. The present review discusses the roles of anterograde and re...