Sazid Zamal Hoque

Sazid Zamal Hoque
Indian Institute of Technology Madras | IIT Madras · Department of Mechanical Engineering

Doctor of Philosophy (Pursuing)

About

16
Publications
3,824
Reads
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37
Citations
Citations since 2016
14 Research Items
37 Citations
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Introduction
I am a doctorate research scholar in the Department of Mechanical engineering, Indian Institute of Technology, Madras, Chennai under the supervision of Prof. Ashis Kumar Sen. Broadly my research interests lie in the area of microfluidics. My research interests include, but not restricted to, acousto-microfluidics, Fluid-structure interactions in low Reynolds number flow, Bio-fluid mechanics. I develop mathematical model by both theoretical and numerical means to understand a physical problem.

Publications

Publications (16)
Conference Paper
Full-text available
In this paper, energy and exergy analysis of a cascaded refrigeration system is presented using a MATLAB code. For the analysis we have considered R−134a and R−32 as refrigerants in the topping cycle (TC) and bottoming cycle (BC) respectively . System COP, refrigerant flow rate, condenser heat loss, compressor work load, component and total system...
Conference Paper
Full-text available
In this paper, a numerical simulation and analysis of supersonic flow over a flat plate using FLUENT packages as well as an in-house solver is presented. In the ANSYS FLUENT platform, Liou and Steffen’s Advection Upstream Splitting Method (AUSM) is used for computing the inviscid fluxes. The in-house solver computes the inviscid fluxes by using the...
Article
We report the fabrication and experimental study of a flexible bi-layer microfluidic device for blood oxygenation, mimicking the thin alveolar exchange barrier constituting a lung. A facile technique is employed to fabricate the device by sandwiching a thin polymeric membrane as the gas exchange layer between two flexible microchannels. A numerical...
Article
Particle-based methods such as smoothed particle hydrodynamics and dissipative particle dynamics are apt for simulating particle-like suspensions in blood. The blood flow through the microvasculature and its dynamics is strongly influenced by the dominant suspensions, and the red blood cells (RBCs) in plasma. The deformation dynamics of RBCs flowin...
Chapter
Microfluidics as a field has a plethora of applications in several fields. From heat transfer to biomedical applications, microfluidic techniques are used to deliver solutions. In the present chapter, we look into the basics of microfluidic techniques used to manipulate tiny volumes of fluids. Further, a detailed discussion on acoustofluidics, lab/...
Chapter
Early detection of infectious diseases by employing point-of-care (POC) technologies, which are highly sensitive and specific, user-friendly, and robust, would find great significance specifically in developing nations. Rapid and real-time detection of such diseases helps in proper treatment and useful in preventing transmission. With the advent of...
Article
Full-text available
Transition between stream and droplet regimes in a coflow is typically achieved by adjusting the capillary numbers (Ca) of the phases. Remarkably, we experimentally evidence a reversible transition between the two regimes by controlling exposure of the system to acoustic standing waves, with Ca fixed. By satisfying the ratio of acoustic radiation f...
Article
The dynamical motion of a pair of microparticles exposed to acoustic standing waves and located at the pressure nodal plane is studied using numerical simulations and experiments. The insight into their dynamical behavior along the pressure nodal plane due to the competition between the axial primary radiation and interparticle forces is elucidated...
Article
Full-text available
Cell lysis is a critical step in genomics for the extraction of cellular components of downstream assays. Electrical lysis (EL) offers key advantages in terms of speed and non-interference. Here, we report a simple, chemical-free, and automated technique based on a microfluidic device with passivated interdigitated electrodes with DC fields for con...
Article
We elucidate interparticle force between a pair of particles suspended in a liquid exposed to a standing bulk acoustic wave. A three-dimensional model based on the perturbation technique and tensor integral method is employed to predict interparticle force by subtracting time-averaged primary radiation force due to scattering effect from time-avera...
Article
Understanding the dynamics of red blood cell (RBC) motion under in‐silico conditions is central to the development of cost effective diagnostic tools. Specifically, unraveling the relationship between the rheological properties and the nature of shape change in the RBC (healthy or infected) can be extremely useful. In case of malarial infection, RB...
Conference Paper
In this paper, we report simulation results assessing the dynamics and deformation of red blood cell (RBC) membrane in a Poiseuille flow. Dissipative particle dynamics (DPD) is employed for the simulation of the motion of a single RBC in a wall bounded shear flow. Starting from the initial stress free shape of the RBC, the cell was found to attain...
Preprint
The dynamics of red blood cells (RBCs) under in-silico conditions is central to the development of cost effective diagnostic tools. Specifically, the rheological properties can unravel the connection between the nature of shape change and the state of RBC (healthy or infected). In case of malarial infection, RBC progressively loses its deformabilit...
Presentation
Full-text available
The state of the red blood cell (either healthy or infected RBC) will influence its deformation dynamics. Since the pathological condition related to RBC, primarily originates from a single cell infection, therefore, it is important to relate the deformation dynamics to the mechanical properties (such as, bending rigidity and membrane elasticity)....
Conference Paper
Full-text available
In present study, dissipative particle dynamics (DPD) simulation of a deformable red blood cell in a micro channel is simulated. The finite sized version of DPD (FDPD) technique is used to represent the red blood cell (RBC) using 50 DPD particles connected by worm like chain (WLC) springs. This model is able to capture mechanical properties of RBC...
Conference Paper
Full-text available
In this study, performance of a combined reheat regenerative steam turbine (ST) based power cycle and a vapor compression refrigeration system (VCRS) is presented and compared with the performance of a similar combined system (CS) integrated with a vapor absorption refrigeration system (VARS). R134a is used as refrigerant in the VCRS while water−Li...

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