
Sayali Bhalchandra ThakareKing Edward Memorial Hospital and Seth G.S. Medical College | KEM Hospital · Nephrology
Sayali Bhalchandra Thakare
DM Nephrology
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36
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Publications
Publications (36)
Acute oxalate nephropathy is a rare but important cause of severe acute kidney injury. We report here two cases presenting as unexplained AKI which were confirmed histologically to be due to acute oxalate nephropathy. Dietary oxalate or its precursor vitamin C was the cause of oxalate exposure in both of these cases. While one patient recovered, an...
Fanconi renotubular syndromes (FRTS) are a rare group of inherited phosphaturic disorders with limited Indian as well as global data on this condition. Here, we describe the experience of a single Endocrinology center from Western India on FRTS.
Comprehensive clinical, biochemical, radiological, management, and genetic details of FRTS patients mana...
Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) is a rare disorder of phosphate homeostasis. We describe a single-center experience of genetically proven HHRH families and perform systematic review phenotype-genotype correlation in reported biallelic probands and their monoallelic relatives. Detailed clinical, biochemical, radiologic...
Proteinuria is the most important diagnostic and prognostic marker in patients with different kidney diseases and in kidney transplant recipients as well. Quantitative estimation of 24-hour protein excretion is considered as a gold standard test for proteinuria. However, 24-hour collections are time consuming, cumbersome, and often inaccurate due t...
Background:
Diarrhea in kidney transplant recipients (KTRs) can be associated with significant morbidity.
Material and methods:
We evaluated 198 KTRs for a history of diarrhea post-kidney transplant at a tertiary care center in western India over 1 year. A protocol-based evaluation of diarrhea was done with respect to clinical features, diagnost...
Lupus nephritis is a severe, organ-threatening manifestation of systemic lupus erythematosus. The current standard of care in the treatment of lupus nephritis is limited to broad-spectrum immunosuppressants, which have significant concerns of short- and long-term toxicity. With traditional approaches, kidney survival and patient outcomes have remai...
Introduction:
Membranous nephropathy, one of the common causes of glomerulonephritis worldwide, is reported in association with mercury exposure. Neural epidermal growth factor-like 1 protein is a recently described target antigen in membranous nephropathy.
Case series:
Three woman (ages 17, 39, and 19 years old) presented sequentially for our e...
Objective:
The long-term renal consequences of curative parathyroidectomy (PTX) in symptomatic primary hyperparathyroidism (sPHPT) are not well characterized. We aimed to assess renal glomerular and tubular functions in an sPHPT cohort at ≥1 year's follow-up.
Design:
Retrospective-prospective study.
Methods:
sPHPT patients with preoperative eG...
Coronavirus disease 2019 (COVID-19) in patients with severe impairment of kidney function is associated with high mortality. We evaluated the effect of high dependency renal unit (HDRU), with nephrologists as primary care physicians, as a quality improvement initiative for the management of these patients. This was a quasi-experimental observationa...
Kidney transplant recipients (KTRs) are at a higher risk for developing severe COVID-19 which can be associated with cardiovascular complications. We studied five KTRs recipients infected with COVID-19 who developed severe cardiovascular complications. Two patients presented with ST segment myocardial infarction and two with clinically suspected my...
Introduction:
Kidney transplant recipients (KTR) are at increased risk of morbidity and mortality due to coronavirus disease 2019 (COVID-19). This study aimed to explore the clinical characteristics and outcomes of COVID-19 in KTR.
Methods:
We reviewed the clinical profile, outcomes, and immunological responses of recipients admitted with COVID-...
Introduction:
The coronavirus disease 2019 (COVID-19) pandemic has caused significant global disruption, especially for chronic care like hemodialysis treatments. Approximately 10,000 end-stage kidney disease (ESKD) patients are receiving maintenance hemodialysis (MHD) at 174 dialysis centers in Greater Mumbai. Because of the fear of transmission...
High Dependency Renal Unit for COVID-19 management in patients with kidney disease on dialysis, KEMH Mumbai
The development and longevity of antibodies against SARS-CoV-2 in kidney transplant recipients (KTRs) is not clear. Though seroconversion has been documented¹, the persistence of this response with time is not established. We longitudinally studied the presence of anti-SARS-CoV-2 IgG antibodies in KTRs after symptomatic coronavirus disease-2019 (CO...
Evidence on the evolution of graft function in kidney transplant recipients recovering from Coronavirus disease - 2019 (COVID- 19) is lacking. This multicenter observational study evaluated the short-term clinical outcomes in recipients with acute kidney injury (AKI) secondary to COVID-19. Out of 452 recipients following up at 5 centers, 50 had AKI...
Background: COVID-19 in patients on dialysis for acute or chronic kidney disease is associated with high mortality. We evaluated the effect of high dependency renal unit (HDRU) with nephrologists as primary care physicians for management of these patients.
Methods: This was an observational, cohort study conducted at a tertiary care teaching hospit...
Background: COVID-19 in patients on dialysis for acute or chronic kidney disease is associated with high mortality. We evaluated the effect of high dependency renal unit (HDRU) with nephrologists as primary care physicians for management of these patients.
Methods: This was an observational, cohort study conducted at a tertiary care teaching hospit...
A considerable number of end-stage renal disease patients undergo tunneled cuffed catheter insertion for hemodialysis under ultrasonographic guidance while awaiting arteriovenous fistula creation. We report a case of a 62-year-old female who underwent tunneled catheter insertion in the left internal jugular vein under ultrasound and fluoroscopic gu...
A 40-year-old previously healthy male presented with acute onset painless dimness of vision in both eyes since the past week and low-grade fever, anorexia and weight loss for the past 1 month. He had been evaluated at a local hospital and diagnosed to have a posterior cerebral artery territory infarct on the left side on the strength of cranial CT....