Sataa Sallami

Endométriose vésicale symptomatique : à propos d'un nouveau cas et revue de la littérature. Satâa SALLAMI | La tunisie chirurgicale-2008 ; Vol 18 Resumé À travers une nouvelle observation d'endométriose vésicale, nous analysons les symptômes permettant d'évoquer le diagnostic et nous étudions les possibilités thérapeutiques. Il s'agit d'une patient...

La malakoplakie est une maladie granulomateuse inflammatoire chronique qui résulte d’un trouble de la digestion enzymatique des germes par les macrophages. Elle atteint préférentiellement l’appareil uro-génital dans près de 75 % des cas. Sa localisation vésicale est relativement fréquente. Elle peut être isolée ou associée à une autre localisation...

Strangulation of the penis is a rare condition that requires emergency management. Several objects, metallic or not, can be placed on the penis to increase sexual performance or for self-erotic intentions especially in psychotic patients with unusual sexual impulses. The problem of removing the foreign body and repairing the damage is a real challe...

Purpose: The authors evaluated the usefulness of the American Association for the Surgery of Trauma (AAST) testis injury scale based on preoperative scrotal ultrasonography (US) and physical examination compared to peroperative findings. Methods: A retrospective review was performed on 107 patients (mean age=29,2±5.8 years) with a testis blunt t...

Purpose: To determine the predictive factors of urinary incontinence (UI) after radical prostatectomy (RP) for localized prostate cancer. Methods: Review of the French and English literature between 1996 and 2015 treating risk factors of UI after RP. Results: We identified 46 articles to be analyzed. Preoperative risk factors of UI were age, B...

Introduction: Data concerning the efficacy of intravesical Bacillus Calmette-Guerin (BCG) on carcinoma in situ (CIS) of the bladder are limited. Objectives: We analyzed long-term outcomes of instillation therapy with BCG to treat bladder CIS, evaluated its effectiveness and safety and searched for prognostic factors that could predict disease re...

Objectifs Évaluer l’efficacité à long terme de la sclérothérapie par le polidocanol dans le traitement de l’hydrocèle testiculaire idiopathique (HTI) chez l’adulte et évaluer la pression hydrostatique intra-vaginale (PIV) comme un facteur pronostic de récidive. Méthodes Entre octobre 2009 et septembre 2014 ; 58 cas d’HTI unilatérale, non cloisonné...

In this work we present two methods based on Association Rules (ARs) for the prediction of bladder cancer recurrence. Our objective is to provide a system which is on one hand comprehensible and on the other hand with a high sensitivity. Since data are not equitably distributed among the classes and since errors costs are asymmetric, we propose to...

Objective: Pre-existing renal lesions (PERL) may interfere with the patho-physiology of trauma, alter the radiographic imaging and influence the therapeutic approach. The aims of this study were to record the PERL found incidentally during blunt renal trauma, to specify the place for effective conservative management and to determin the estimated...

Aim: to make an inventory of the prevalence, the severity, the reasons for the patient's consultation and the therapeutic measures indicated by urologists for erectile dysfunction (ED) in the west of Algeria. Methods: This survey was conducted among 4 urologists. All male patients, aged over 18 years, presenting to clinics during the study perio...

Background: (PSMA+,PSA+) and (PSMA+,PSA-) are the two most individual clones that we have previously identified during prostate cancer (PC) progression. However, molecular signatures associated with these distinct PSMA-PSA prostate clones and their specific correlation with disease outcome is yet to be defined. Aim: Since Akt is a major pathway...

long-term outcome of intravesical bacillus calmette-guérin therapy with maintenance for urinary bladder carcinoma in situ: about 47 cases evolution à long terme du carcinoma in situ de la vessie traité par Bcg thérapie endo-vésicale: a propos de 47 cas r é s u m é Introduction: Les données relatives à l'efficacité du Bacillus de Calmette-Guérin (BC...

Only 166 cases of renal malignant tumors in Horse shoe Kidneys have been reported on the international literature up to July 2006, 30 other cases by June 2013. . A Horse shoe Kidney presents a unique anatomic challenge secondary to its low fixed location, abnormal vasculature and presence of an isthmus. The blood supply to the HK is often atypical...

Background: (PSMA+,PSA+) and (PSMA+,PSA-) are the two most individual clones that we have previously identified during prostate cancer (PC) progression. However, molecular signatures associated with these distinct PSMA-PSA prostate clones and their specific correlation with disease outcome is yet to be defined. Aim: Since Akt is a major pathway...

The management of urolithiasis in patients with haemophilia poses a real challenge to the urologist. We conducted a systematic literature review to assess the safety and efficacy of extracorporeal shock wave lithotripsy (ESWL) in the treatment of urolithiasis in hemophiliacs. A systematic review was conducted by using the National Library of Medici...

Imaging findings of urinary tuberculosis (TB) on excretory urography (IVP) and CT have been reported to be nonspecific although CT may provide detailed informations. We performed a retrospective study of patients with proven urinary TB to compare imaging findings on IVP and CT and to make a systemic approach to imaging analysis of urinary TB. Urina...

The relevance of prostate specific antigen (PSA)-prostate specific membrane antigen (PSMA) profiles in pathologic prostate (hyperplasia and cancer) has not been fully understood. The aim of this study is to investigate the impact of PSA-PSMA profiles on sera PSA levels and angiogenic activity in benign prostate hyperplasia (BPH) and prostate carcin...

Prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA) measured in serum are not fully satisfactory as biomarkers of prostate cancer (PC). Results obtained in this article indicated that PSMA/PSA ratio evaluated by immunohistochemistry in normal prostate (NP), benign prostatic hyperplasia (BPH), and PC at the individual level...

Background: Bladder papillomatosis is a diffuse tumor proliferation even up almost all of the bladder mucosa. We analyzed prognosis of this rare entity after conservative treatment. Methods: We retrospectively analyzed epidemiological, clinical, therapeutic and evolutive data in 24 patients with newly diagnosed bladder transitional cell carcinom...

Aim: To investigate the characteristics of urolithiasis associated with Crohn's disease (CD) in a sample of Tunisian population. Methods: We retrospectively studied 184 patients with CD to reveal any urolithiasis during evolution. Evidence for the presence of renal calculi was obtained from plain films, ultrasonography or intravenous urography a...

Background: As promising targets for in vivo diagnostic,prognostic and therapeutic approaches, the distribution and staining pattern of prostate specific antigen (PSA) and prostate specific membrane antigen (PSMA) in tumors are of significant interest. Aims: To compare the cellular distribution and heterogeneity of PSA and PSMA expression in nor...

We have investigated the expression of prostate-specific membrane antigen (PSMA) and prostate-specific antigen (PSA) transcripts in androgen-dependent (LNCaP) and androgen-independent (22Rv1) prostate cancer cell lines. We also enquired whether Q640X CTE-truncated androgen receptor (AR) has an impact on transcription of mRNA for PSMA and PSA in tra...

Horseshoe kidney is a rare congenital malformation predisposing the patient to urinary tract infections. We present a case of a renal abscess occurring in an adult patient with a horseshoe kidney. A computed tomography scan confirmed the diagnosis of an abscess in the isthmus of the horseshoe kidney. A compete regression of the abscess was achieved...

Purpose: To investigate differences in the biological features of the most immunoexpressed prostate cancer (PC) profiles (PSA+, PSMA+) according to the RKIP. Methods: 19 PC with dominant Gleason grade ≥ 8 were studied. Expression of PSA, PSMA, RKIP, Raf-1, MEK-1, ERK-1, ERK-2, p-Akt (T308), p-Akt (S473), NF- κ B p50, and NF- κ Bp65 were detected...

In this study we investigate differences in the biological features between two most abundant pro state tumor profiles (PSMA+, PSA+) and (PSMA+, PSA-) in benign prostatic hyperplasia (BPH) and prostate cancer (PC) tissues according to the activation of AKT (T308/S473) and angi ogenic activity. This study was carried out in 6 normal prostates (NP),...

A comparison of the biological features of prostate cancer with (PSA+,PSMA+) profile according to RKIP Awatef Ben Jemaa 1*, Yosra Bouraoui ¹, Sataa Sallami ², Yassine Nouira ² and Ridha Oueslati ¹ • 1 Unit of Immunology and Microbiology Environmental and Carcinogenesis (IMEC),Faculty of Sciences of Bizerte, 7021, Zarzouna, University of Carthage,...

The aim of the present work was to study the expression of the proinflammatory cytokine, interleukin-6 (IL-6), mediated by bFGF signaling and its possible crosstalk with prostate-specific membrane antigen (PSMA) in LNCaP and PC3-PSMA prostate cancer cell lines. PC3 cells stably transfected with PSMA gene were used for restoring PSMA expression. LNC...

Background: The importance of minimally invasive surgery in urology has constantly increased in the last 20 years. Endoscopic resection of prostate and bladder tumors is actually a gold standard with many advantages for patients. Aim: To analyze the problems related to the ergonomic conditions faced by urologist during video endoscopic surgery b...

Background: Iatrogenic ureteral injuries are not so rare and may have serious medicolegal repercussions. Aim: To report a case of iatrogenic ureteral injury, secondary to ureterolysis and treated by substitutive non-modeled ureteroileoplasty. Case report: A 70-year-old man, who presented extrinsic ureteral compression due to idiopathic retrope...

Background: Fournier's gangrene (FG) is a serious, extensive fulminant infection of the genitals and perineum. Indeed, despite antibiotics and aggressive debridement, the mortality rate of FG remains high. Aim: Through our experience, we intent to identify effective factors in the survival of patients with FG and we try to determine how the Four...

Ureteric injury is a potential complication in various surgical procedures. The incidence varies between 0.5% and 10%. The risk of such complications is mainly related to the complexity of the surgical procedure and the presence of eventual periureteric pathology. The most effective measure to prevent iatrogenic injury is to have a sound knowledge...

Blunt abdominal trauma with an isolated abnormal kidney rupture is a rare clinical entity. The correct preoperative diagnosis may be difficult and challenging because of the insidious onset, lack of obvious bleeding, and, frequently, lack of urinary symptoms. We present a case of a 22-year-old female with isolated pelvic rupture of a hydronephrotic...

Aim: To analyze the testicular cancer (TCa) incidence, diagnosis aspects, pathologic grade, stage, and survival in Tunisian men. Methods: We studied all patients who had histopathologically confirmed TCa treated in La Rabta University-Hospital between 1991 and 2010. Baseline demographic data included age at diagnosis, year of diagnosis, clinical...

Vesicouterine fistula (VUF) is an abnormal communication between the posterior wall of the bladder and the anterior wall of the uterus. Although it represents only 1 to 4% of all urogenital fistulae, its prevalence is increasing all over the world because of the large indications of cesarean section. VUF usually presents with urine leak, amenorrhoe...

Bachground: Bone metastasis is very frequent in prostate cancer. It is a turning point that marks the severity of the disease. Before metastasis become symptomatic, treatment preventing bone events should be indicated. Aim: To evaluate the role of bisphosphonate in the treatment of bone metastases from prostate cancer. Methods: A review of literatu...

Crohn's disease often is detected in adolescents with nonspecific gastrointestinal complaints. Extraintestinal complications are common but usually follow the onset of the bowel complaints. We present an unusual case in which scrotal swelling was the first symptom in a patient discovered to have Crohn's disease. This is particularly unusual in that...

Background: The natural history of bladder transitional cell carcinoma (TCC) in young patients remains a matter of debate. Purpose: To compare the clinicopathological characteristics and the prognosis of bladder TCC according to age in young adults. Materials and methods: From 1993 to 2006, 158 patients ≤ 50 years with newly diagnosed bladder TCC w...

The nutcracker syndrome refers to compression of the left renal vein between the aorta and the superior mesenteric artery. It may be asymptomatic for long period and constitute casual findings. To report a new case diagnosed by radiological exploration after an abdominal trauma. The diagnosis and treatment of nutcracker syndrome are discussed. A 32...

This study was designed in order to analyze the expression of the transduction pathways TRAF-2/ASK-1/MEK-6/Pp38 and NF-xB/p65, involved in the proliferation/apoptosis equilibrium in normal and pathological conditions. The study was carried out in 5 Normal Prostates (NP), 24 Benign Prostate Hyperplasia (BPH) and 19 Prostate Cancers (PC). Immunohisto...

This article presents the actual state of urology and highlights some of the most significant challenges facing resident urological training in Tunisia. These include a specifically limited number of trained urologists, limited training capacity, limited availability of some modern equipment, and non-recognition of subspecialties related to urology...

The Bellini collecting duct carcinoma (CDC) is a very rare form of renal cell carcinoma (1%) associated with an extremely poor prognosis. To study clinical and radiological characteristics of CDC. From 1993 to 2002, 7 patients with CDC were treated at our institution. The diagnosis of CDC was made by a nephrectomy specimen in all cases. Demographic...

The transitional cell carcinoma within the bladder diverticular is a rare and poorly known entity. To evaluate diagnostic and therapeutic approaches of transitional cell carcinoma within the bladder diverticular. Thirty men and two women (median: 70 years; 44- 83 years) were included. The main reason for consultation was hematuria. The intra-divert...

Renal colics due to urinary stones are also common in women of childbearing age whether pregnant or not. AIM : Through a review of literature, we evaluated diagnostic and therapeutic approaches in renal colic in pregnancy and lactation. Review of literature. The clinical diagnosis is sometimes difficult requiring additional medical imaging based on...

To evaluate the efficacy and side-effects of Polidocanol used as sclerosing agent for testicular hydrocele. One hundred and ninety men, with a median age of 55,9 years (40-89), treated for idiopatic hydrocele were assessed. After puncture and aspiration, the empty sac was instilled with 3% Polidocanol. We recorded recurrence, complications and asso...

INTRODUCTION: The prognostic significance of pyelum versus ureteral urothelial carcinomas is controversial. The objective of the study was to evaluate the prognostic value of the anatomical location of transitional cell carcinoma (TCC) in the upper urinary tract. METHODS: We retrospectively analyzed data from 51 patients with upper urinary tract TC...

INTRODUCTION: The purpose of the study was to compare clean intermittent catheterization (CIC) after endoscopic urethrotomy for urethral stricture (US) using a low-friction hydrophilic catheter or standard Nelaton polyvinyl chloride (PVC) catheter in a randomized study. Patient satisfaction, complications, and US recurrence were determined. METHODS...

We report a case of severe bilateral distal ureteral stenosis in a 76-year-old male. The stenosis was caused obstructive renal failure after transurethral resection of a periorificial bladder tumor and early postoperative bacillus Calmette-Guerin therapy instillation to prevent recurrence.

Megacalyces is a rare congenital urinary anomaly consisting of nonobstructive dilated calyces. The renal pelvis and ureter have a normal caliber. We report an asymptomatic unilateral megacalyces in a 22-year-old woman. She had an increased number of dilated calyces on the right kidney and a cluster of small calculi over the lower pole. The largest...

Eosinophilic cystitis is a rare inflammatory pathology. It remains a poorly understood entity. To report a series of adult cases of eosinophilic cystitis mimicking a bladder tumor. Retrospective study of cases of eosinophilic cystitis collected in an urology department. Diagnosis was established on a spontaneous bladder perforation in one case and...

Cryptorchidism is a pathological condition defined as the failure of the testis descending into the scrotum. It is a rare condition in adults. To study clinical and therapeutic aspects of cryptorchidism in adults. A retrospective study of a series of 100 adult patients (mean age: 25.1 years; 19-50 years) with cryptorchid testis admitted in an urolo...

Explosion inside the bladder occurring during transurethral resection is rarely recognized as a complication of endoscopic resection of bladder tumors. We report a case of intravesical explosion during an endoscopic resection of a bladder tumor. Damages to the bladder were minor. We discuss the possible causes of this complication as well as the di...

Background: The distension of the pelvis and calyces of the kidney due to the obstruction and stasis of urinary flow or Hydronephrosis, caused by a lesion in the upper or lower urinary tract. The giant hydronephrosis (GH) is a rare entity and its etiologies are varied. Most reported cases of GH occur in infants and children, and are congenital in o...

Background and Aims: Although perforation of the uterus by an intrauterine contraceptive device is not uncommon, intravesical migration and secondary stone formation is a very rare complication. We report a series of 10 women in whom an intrauterine contraceptive Copper-T device migrated from the uterus to the bladder and resulted in formation of a...

Genitourinary Tuberculosis (TB) is a rare extra pulmonary manifestation of TB. We report a patient who presented with right flank pain and weight loss. Imaging revealed a solid mass at the lower pole of the right kidney. A partial nephrectomy was performed and histopathology confirmed the diagnosis of pseudo-tumoral renal tuberculosis. Patient had...

The present study was undertaken to relate the co-expression of prostate-associated antigens, PSMA and PSA, with the degree of vascularization in normal and pathologic (hyperplasia and cancer) prostate tissues to elucidate their possible role in tumor progression. The study was carried out in 6 normal, 44 benign prostatic hyperplastic and 39 cancer...