Sasan Asiaei

Iran University of Science and Technology · School of Mechanical Engineering

In harsh climates like Iraq, characterized by extreme temperatures and energy shortages, dynamic insulation technology holds great potential to significantly reduce energy consumption and enhance thermal comfort. Dynamic insulation technology reduces building energy consumption by adjusting thermal conductivity based on climate changes. This articl...

Dynamic insulation technology adjusts thermal resistance to reduce building energy consumption in response to climate changes. Sustainable building practices prioritize optimizing the building envelope to enhance energy efficiency and regulate the interaction between indoor and outdoor environments. The previous part of this study (Part A) provided...

Background: Scar is an unpleasant skin lesion that occurs following deep wounds or burns. The application of local triamcinolone is a common treatment for scar treatment and prevention, which should be repeated several times in conventional dosage forms. An effort has been made here to provide a prolonged triamcinolone dermal delivery by microneedl...

Droplet-based microfluidics, including the controlled manipulation of materials in the form of monodisperse droplets on the micrometer scale in microfluidic chips, has gained much attention due to their ability in biological assays. The capillary number of the continuous phase, as the ratio of viscous force and interfacial tension, is so important...

The ever-increasing demand for electronic systems to enhance their performance and processing speed has exponentially increased their heat generation, especially those containing microstructures with reduced surface area. Tackling these complex thermal management challenges creates an urgent need to design and model compact efficient cooling system...

Most topical drug delivery techniques do not provide therapeutic concentrations for treatment of surgical site and other local infections and, therefore, require some kind of enhancement, such as physical methods like microneedles, the subject of the present investigation. Here, controlled-release long-lasting antibacterial polylactic acid (PLA) mi...

Many microfluidics methods have been proposed for filtering, focusing, and separation, among which DC-iDEP is accounted as one of the most straightforward approaches from fabrication and implementation aspects. Former studies focused on improving the geometrical features of simple/straight iDEP channels. This paper concentrates on developing a vers...

Dysregulation of nitric oxide (NO) and it’s two relatively stable metabolites, nitrite, and nitrate, in SARS-CoV-2, are reported in infected populations, especially for nitrates levels > 68.4 μmol/L. In this paper, we measure the abnormal presence of nitrite in the saliva by developing a cheap μPAD for colorimetric detection through the modified Gr...

Sustainable provision of freshwater for hot arid coastal regions with abundant solar radiation solves pivotal developmental rural and urban problems. This article presents a thermodynamic investigation of a novel poly-generation smart grid system to produce power and water in a cleaner way via the integration of a multi-effect distillation (MED), c...

A volume of fluid-based lattice Boltzmann method (VOF-LBM) is developed, using the open-source parallel lattice Boltzmann solver library (Palabos) to study the wettability of solid surfaces and include the droplets’ dynamic behavior. This improves the accuracy and diminishes limitations on the density and viscosity ratios and the outcoming spurious...

Microfluidic droplet generation has turned into a popular method for microencapsulating active microparticles for biomedical applications. In order to increase the efficiency of this method, getting to know the process of microparticle formation in these systems and the factors affecting it is of great importance. In this research, the mechanism of...

Coronavirus and its spread all over the world have been the most challenging crisis in 2020. Hospitals are categorized among the most vulnerable centers due to their presumably highest traffic of this virus. In this study, centrifugal isolation of coronavirus is successfully deployed for purifying hospitals’ air using air conditioners and ducts, su...

The flow characteristics and mixing efficiency in a novel chaotic micromixer is numerically investigated from both eulerian and lagrangian viewpoints. The configuration consists of four successive quadrant units organized in a non-planar arrangement. A scalar equation is solved alongside conversation equations to determine the concentration of dye...

A cheap/rapid technique for the fabrication of μPADs is presented for point of care analysis. Hydrophobic channels were formed across the width of the paper by spraying hot pure wax. This biocompatible novel process yielded uniform 300±5 μm hydrophilic microchannels on paper, without the use of the cleanroom, UV lamp, or organic solvents and was co...

The simultaneous flow of gas and liquids in large scale conduits is an established approach to enhance the performance of different working systems under critical conditions. On the microscale, the use of gas-liquid flows is challenging due to the dominance of surface tension forces. Here, we present a technique to generate common gas-liquid flows...

The simultaneously flow of gas and liquids in large scale conduits is an established approach to enhance the performance of different working systems in critical conditions. In micro scale, the gas-liquid flow and its advantages are perplexing due to hydrodynamic forces require mostly single-phase flow regimes. We have devised a technique that make...

n this paper, we have numerically examined the steady boundary layer of a viscous incompressible nanofluid and its heat and mass transfers above a horizontal flat sheet. The boundary conditions considered were a nonlinear magnetic field, a nonlinear velocity and convection. Such nonlinearity in hydrodynamic and heat transfer boundary conditions and...

In this article, we present a novel concept for centrifugal pumping of fluid, harnessing the inertial braking forces in a microfluidic compact disk. Due to deceleration of the disk, torque and inertia forces are exerted on the bulk fluid that is coupled to momentum equation for prediction of the developed pressure that drives the liquid. Head losse...

One of the ongoing challenges in lateral flow Immunochromatographic assays (LFIA), is lowering the limit of detection and enhancing their signal quality, i.e. the color intensity. There are a number of rather costly and complicated processes for this aim, such as the use of functionalized materials/membranes and additional spectroscopic readout uni...

In this work, we design a novel microfluidic chip to analyze and simulate the thermophoretic isolation of circulating tumor cells. For the first time, separation of circulating tumor cells from same size peripheral blood cells is examined by thermophoresis. Moreover, a discrete heat source was used to attenuate the separation efficiency, instead of...

Mixed convection of Cu-water nanofluid inside a two-sided lid-driven enclosure with an internal heater, filled with multi-layered porous foams is studied numerically and its heat transfer and entropy generation number are evaluated. Use of multi-layered porous media instead of homogeneous ones is capable of heat transfer enhancement, by weakening f...

To extract optimum cooling trends in a heavy duty engine, the 3D flow in a centrifugal pump from the Detroit Diesel company was numerically simulated. For this aim, a computational fluid dynamic model is developed using ANSYS CFX for a wide span of flow rates and a number of shaft angular velocities. The variation of constituting parameters are exa...

Restrictive emission regulations and climate change are the main motivations for improving engine combustion characteristics to decrease engine-out emissions and fuel consumption. Fuel additives are effective solutions to improve fuel properties to address these challenges. In this study, simultaneous application of water and cerium oxide nanoparti...

In this article, we have enhanced the sensitivity and limit of detection of lateral flow immunoassay tests, exemplified for the detection of human chorionic gonadotropin (pregnancy) through determination of proper test line position. Test line position affects the flow velocity and concentration profile of analytes at the test line, which itself im...

A smartphone-based microfluidic platform was developed for point-of-care (POC) detection using surface plasmon resonance (SPR) of gold nanoparticles (GNPs). The simultaneous colorimetric detection of trace arsenic and mercury ions (As³⁺ and Hg²⁺) was performed using a new image processing application (app). To achieve this goal, a microfluidic kit...

We have enhanced the performance of lithographically patterned microchannels on paper and tailored it to a do it yourself method by examining the impact of each microfabrication step on surface properties. Modification of photoresist spreading, baking, exposure and developing steps improved paper and channels quality and decreased fabrication costs...

Myocardial infarction is a leading cause of morbidity and mortality. In this study, using Cine MRI images, the infarct region was precisely determined by examining the local migration path length of critical points on myocardium borders and the fractional thickening effects. First, MRI Cine images of Epi/Endocardium were processed in 3D for all sli...

The insole shape and the resulting plantar stress distribution have a pivotal impact on overall health. In this paper, by Finite Element Method, maximum stress value and stress distribution of plantar were studied for different insoles designs, which are the flat surface and the custom-molded (conformal) surface. Moreover, insole thickness, heel’s...

The kinetics of microfluidic-based thiolic self-assembled monolayer (SAM) formation on the metallic surfaces has been studied through numerical simulation. The computational model simultaneously solves the equations of thiols’ mass transport, a two-dimensional diffusion-convection, coupled to the one-dimensional self-assembly on the metallic surfac...

This research reports an improved conjugation process for immobilization of antibodies on carboxyl ended self-assembled monolayers (SAMs). The kinetics of antibody/SAM binding in microfluidic heterogeneous immunoassays has been studied through numerical simulation and experiments. Through numerical simulations, the mass transport of reacting specie...

This study presents an improved kinetics for the formation of self-assembled monolayers (SAMs) of thiols on gold substrates. Based on predictions of a computational model developed to study the SAM growth kinetics, SAMs of 11-mercaptoinic acid and 1-octanethiol were successfully formed for the first time within 15 minutes by incubation of planar go...

This study demonstrates improved kinetics for the formation of self-assembled monolayers (SAMs) of alkanethiols on gold nanoparticle substrates. A computational model was developed to predict SAM growth kinetics. Based on the predictions from the model, SAMs of 11-mercaptoundecanoic acid (11-MUA) and 1-octanethiol (1-OT) were formed by incubation o...

Recently, the analysis and prototyping of biologically inspired adhesive pads have been the subject of growing interest. Similar to biological counterparts, these synthetic adhesives consist of rafts of tiny protruding fibers. The adhesion performance of these micro-engineered products is highly dependent on the geometrical and mechanical propertie...

The main objective of this study was to study the effects of length, alignment and diameter distribution of the carbon nanotubes (CNTs) on the percolation threshold of nanocomposites using computational simulations. Furthermore, the effects of the aforementioned parameters on the efficiency of the produced networks are investigated. The best distri...