Sarwan Kumar

• MD
• Wayne State University

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

Aim: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) lower anthracycline-induced cardiotoxicity. Methods: PubMed and Google Scholar were searched until September 2023 for studies regarding SGLT2i for treating anthracycline-induced cardiotoxicity. Overall mortality and cardiovascular events were considered. Using a random-effects model, data pool...

Background : Several randomized clinical trials have been conducted assessing the potential efficacy of X receptor (FXR) agonists in patients with metabolic dysfunction-associated liver disease (MASLD). A comprehensive review and analysis were needed to evaluate the findings of these trials. Hence, this systematic review and meta-analysis aim to st...

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

Objective This paper aims to provide a comprehensive overview of the pathophysiology of Atrial Fibrillation (AF) and Coeliac Disease (CD) individually, while also exploring the emerging evidence of a potential association between the two conditions. Methods The pathophysiology of AF, the most prevalent arrhythmia globally, and CD, an autoimmune co...

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

Endometrial cancer is one of the most prevalent tumours in females and holds an 83% survival rate within 5 years of diagnosis. Hypoestrogenism is a major risk factor for the development of endometrial carcinoma (EC) therefore two major types are derived, type 1 being oestrogen-dependent and type 2 being oestrogen independent. Surgery, chemotherapeu...

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

Background In this study, we aim to discuss long term clinical outcomes of Intravascular-imaging guided PCI versus angiography-guided PCI in complex coronary lesions over a mean period of two years. Methods A systematic search and meta-analysis were conducted to assess the efficacy of using Intravascular Ultrasound or Optical Coherence Tomography...

The connection between cardiovascular illnesses and the gut microbiota has drawn more and more attention in recent years. According to research, there are intricate relationships between dietary elements, gut bacteria, and their metabolites that affect cardiovascular health. In this study, the role of gut microbiota in cardiovascular disorders is e...

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

Esophageal cancer is a major cause of cancer-related mortality worldwide, with significant regional disparities. Early detection of precursor lesions is essential to improve patient outcomes. Artificial intelligence (AI) techniques, including deep learning (DL) and machine learning (ML), have proved to be of assistance to both gastroenterologists a...

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

originally published at KevinMD.com and the hyperlink to the original is in the title of the full text PDF for direct access to the original

Purpose: USCDT is evolving as a popular treatment for PE. Studies have shown that USCDT causes significant reduction in RV strain and pulmonary hypertension risk. However, impact of these treatment modalities on clinical outcomes remains unclear. We conducted meta-analysis of observational studies to assess safety and mortality outcomes of USCDT co...

The Wayne State University Office of Graduate Medical Education (WSUGME) uses an objective structured clinical examination (OSCE) to assess its programs’ contribution to enhancing residents’ communication skills. In response to revisions in Michigan’s opioid-prescribing mandates in 2017, WSUGME developed a pain management case in collaboration with...

Background Cardiac stress testing is a validated diagnostic tool to assess symptomatic patients with intermediate pretest probability of coronary artery disease (CAD). However, in some cases, the cardiac stress test may provide inconclusive results and the decision for further workup typically depends on the clinical judgement of the physician. The...

Background: High-quality transitions of care are crucial for patient safety in hospitals, yet few undergraduate curricula include transition-of-care training. In 2012, the Wayne State University Office of Graduate Medical Education (WSUGME) required its residency programs to use the SAIF-IR mnemonic (summary, active issues, if-then contingency plan...

The mortality associated factors can be quantified in terms of proportionate mortality ratios (PMR) per National Occupational Mortality Surveillance (NOMS) data. Therefore, we explored NOMS data for the United States (U.S.) occupational workers’ mortality during 1999, 2003-2004, 2007-2014 to compare physicians’ mortality associated factors to the m...

Introduction: Coronaviruses are a large family of viruses that have been around for many years and may cause illness in humans or animals. In early December 2019, the first pneumonia cases related to the coranoavirus were found which has since led a pandemic. Coronaviruses bind to their target cells through angiotensin-converting enzyme 2 (ACE2), w...

Background: The efficacy of antidiabetic agents for the treatment of non-alcoholic fatty liver disease (NAFLD) remains unclear. Aim: To conduct a meta-analysis to study the efficacy of pioglitazone and three novel anti-diabetic agents: glucagon-like peptide-1 (GLP-1) agonists, sodium-glucose co-transporter-2 (SGLT2) inhibitors, and dipeptidyl-pe...

Background The right problem for graduate medical education (GME) program directors is whether diversity in their GME programs is as good as diversity in feeder entities to their GME programs. Generally, the feeder entities to GME residency programs are their affiliated medical schools. However, the specific feeder entities to GME residency program...

Background: Syncope is one of the most common reasons for emergency department visits. The most common causes of syncope include vasovagal, orthostatic, neurogenic and cardiogenic. In some cases, history and physical examination can point towards a specific cause. While in most cases, history and physical alone are insufficient to indicate an obvio...

While SEARCHING OUR-OWN HEALTH AFTER MEDICINE (SOHAM), we as aging physicians have to first explore and expose our mortality with underlying uniqueness of causes for physician mortality. Herein, publicly available data at Centers for Disease Control and Prevention from National Occupational Mortality Surveillance program of the National Institute f...

Background Catheter-based renal denervation has significantly reduced blood pressure in previous studies. Following a positive pilot trial, the SPYRAL HTN-OFF MED (SPYRAL Pivotal) trial was designed to assess the efficacy of renal denervation in the absence of antihypertensive medications. Methods In this international, prospective, single-blinded...

Intravenous (IV) hydralazine, enalapril and labetalol are oftentimes used without indication for the treatment of asymptomatic hypertension in the hospital setting and have been shown to have substantial adverse effects that are associated with increased morbidity and mortality, as well as longer length of stay. Their use is also associated with gr...

INTRODUCTION Liver enzyme elevation is a common condition among diabetic patients and often Nonalcoholic Fatty Liver Disease is responsible for this,which can lead to fibrosis and cirrhosis. GH should be one of the differential diagnoses upon exam of a patient with uncontrolled DM with elevated transaminases and hepatomegaly. Compared to other live...

PURPOSE The purpose of this study is to investigate the potential benefits of dexmedetomidine when combined with benzodiazepine for alcohol withdrawal syndrome (AWS) in the intensive care unit (ICU). METHODS This is a retrospective cohort study. Charts of ICU patients with AWS were reviewed and were divided into the study group (benzodiazepine and...

The Centers for Disease Control and Prevention have put forth recommendations to document events in terms of well-defined categories of self-directed violence even though the evolution of terminology for decriminalization and de-stigmatization from “self-murder” to “suicide” to “self-directed violence” may be just avoiding calling a spade a spade....