Sareesh Naduvil Narayanan

University of Central Lancashire | UCLAN · School of Medicine

It is quite difficult to teach complex topics like the physiology of vestibular apparatus to undergraduate students. Understanding the orientation and mode of stimulation of receptors in vestibular apparatus is also quite challenging for the students. As faculty we attempt to use innovative methods to teach physiology and enhance student learning....

Publisher link to access the full text of the article: http://link.springer.com/article/10.1007/s11011-015-9689-6/fulltext.html The effects of chronic and repeated radiofrequency electromagnetic radiation (RFEMR) exposure on spatial cognition and hippocampal architecture were investigated in prepubescent rats. Four weeks old male Wistar rats were...

Full Text Available Online @ https://authors.elsevier.com/a/1WWIk4wOUnjvu4 The purpose of the study was to evaluate the changes in amygdala morphology and emotional behaviors, upon exposure to chronic RF-EMR in adolescent rats. Four weeks old male albino Wistar rats were exposed to 900 MHz (power density:146.60 μW/cm2) from a mobile phone in sile...

Although traditional didactic lecturing is the principal instructional approach used in numerous medical schools, this method has several limitations. Experiential learning approaches place students in the center of the learning process and creates a positive and supportive classroom learning environment. In this article, we propose an active pedag...

Emerging viral infections are a ceaseless challenge and remain a global public health concern. The world has not yet come back to normal from the devastating effects of the highly contagious and pathogenic novel coronavirus, or Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Olfactory and taste dysfunction is common in patients infect...

Among the various systems taught in the preclinical phases, the nervous system is more challenging to learn than other systems. In this report, a novel teaching methodology, ‘real-life scenario (RLS) blended teaching’ is described and its effectiveness in facilitating inquisitive learning in undergraduate medical students was evaluated. This mixed-...

Background: To understand the role of smoking in influencing endothelial function as assessed by LDF among non-smoker and smoker males. Methods: The LDF measurement for a total of 35 non-smokers and 16 smokers was done in the central research laboratory after written informed consent. The change in LDF signal in response to acetylcholine 100 µl, wh...

Among the various systems taught in the preclinical phases, the nervous system is more challenging to learn than other systems. In this report, a novel teaching methodology, 'real-life scenario (RLS) blended teaching' is described and its effectiveness in facilitating inquisitive learning in undergraduate medical students was evaluated. This mixed-...

Conventional camera lucida (CL) aided neuronal tracing technique for studying neural plasticity is a demanding procedure. Stereo Investigator-Neurolucida enabled neuronal tracing system is not accessible to all researchers. This necessitates alternate simple and less challenging digitised neuronal tracing methods. This report describes a novel digi...

Epigenetic mechanisms, which include DNA methylation, a variety of post-translational modifications of histone proteins (acetylation, phosphorylation, methylation, ubiquitination, sumoylation, serotonylation, dopaminylation), chromatin remodeling enzymes, and long non-coding RNAs, are robust regulators of activity-dependent changes in gene transcri...

Introduction: Isometric Hand Grip (IHG) strength measurement is extensively used in many areas of medicine and sport science as a functional test of overall strength. By testing the IHG strength, maximum isometric strength of the hand and forearm muscles can be estimated. Weak hand grip strength is a key component of sarcopenia and is associated wi...

Golgi staining allows for the analysis of neuronal arborisations and connections and is considered a powerful tool in basic and clinical neuroscience. The fundamental rules for improving neuronal staining using the Golgi-Cox method are not fully understood; both intrinsic and extrinsic factors may control the staining process. Therefore, various co...

Background: The Stroop Colour and Word Test (SCWT) is the most extensively used neuropsychological test in humans to evaluate the ability to inhibit cognitive interference. Any music played while the listener's primary attention is focused on another activity is known as background music and its effects on SCWT have not been studied well. Objecti...

The primary objective of mobile phone technology is to achieve communication with any person at any place and time. In the modern era, it is impossible to ignore the usefulness of mobile phone technology in cases of emergency as many lives have been saved. However, the biological effects they may have on humans and other animals have been largely i...

In the behavioral science field, many of the oldest tests have still most frequently been used almost in the same way for decades. The subjective influence of human observer and the large inter-observer and interlab differences are substantial among these tests. This necessitates the possibility of using technological innovations for behavioral sci...

Aims The aim of the study was to investigate the effects of exposure to enriched environment (EE) on passive avoidance learning and hippocampal cellular morphology in rats exposed to chronic restraint stress. Materials and Methods Adult male albino Wistar rats were assigned into the following groups: normal control (NC) remained undisturbed in the...

In the present study, the effect of 900 MHz radiation exposure on blood biochemical and reproductive parameters was evaluated in adolescent rats. Male albino Wistar rats (8-10 weeks of age) were exposed to 900 MHz radiation (1hr/day, power density - 146.60 µW/cm2) from a mobile phone for 28 days. On 29th day the animals were euthanized and malondia...

The present study reports perceptions of first-year undergraduate medical students (n = 120), regarding modified directed self-learning (DSL) sessions in physiology. Students were provided with prereading assignments (faculty developed PowerPoint slides containing diagrams with incomplete labeling/ flowcharts with missing steps) pertaining to the D...

Marsilea quadrifolia Linn. (MQ) has been used for insomnia and epileptic disorders in traditional Indian medicine. The present study is to isolate the active component responsible for antiepileptic property of MQ by evaluating its ability to minimize the reactive oxidative damage in brain due to chronic epilepsy in rat. 1- Triacontanol cerotate (1T...

Background: Golgi–Cox staining method is considered as one of the best neurohistological and fascinating staining techniques to reveal the cytoarchitecture of the brain. Requirement of longer time (more than a month), laborious section processing steps, requirement of sophisticated equipment’s and costly ready to use kits limits extensive use of th...

For free access to full article: http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=3853&category_id=110&option=com_virtuemart&Itemid=1 Aim: In the current study, the effects of 900 MHz radio-frequency electromagnetic radiation (RF-EMR) on levels of thiobarbituric acid-reactive substances (TBARS), total antioxidan...

The long lasting behavioural and cognitive impairments in offspring prenatally exposed to nicotine have been confirmed in animal models. In the present study, we investigated the effect of ascorbic acid on prenatal nicotine exposure induced behavioral deficits in male offspring of rats. The pregnant Wistar dams were divided into four groups of six...

Objective: To study the anti-epileptic effects of methanolic extract of Marsilea quadrifolia Linn. (MQ) in maximal electroshock (MES) and pentylenetetrazole (PTZ) induced rat models of epilepsy. Method: A total of 84 adult male Wistar rats were used. An acute oral toxicity study was conducted on 36 rats and the remaining were used for other expe...

Appendectomy is the surgical procedure of removal of appendix. The inflamed or diseased condition of appendix also known as appendicitis is a common occurrence and is a surgical emergency. It commonly occurs due to obstruction of its lumen. The comprehensive information about the trends in the clinical profile of the appendicitis and appendectomy a...

In the current study the modulatory role of mobile phone radio-frequency electromagnetic radiation (RF-EMR) on emotionality and locomotion was evaluated in adolescent rats. Male albino Wistar rats (6-8 weeks old) were randomly assigned into the following groups having 12 animals in each group. Group I (Control): they remained in the home cage throu...

AIM: In the current study we evaluated adverse effects of monosodium glutamate (MSG) on memory formation and its retrieval as well as the role of ascorbic acid (Vitamin-C) in prevention of MSG-induced alteration of neurobehavioral performance in periadolescent rats. MATERIALS AND METHODS: Healthy male albino Wistar rats (4-6 weeks old), were random...

The interaction of mobile phone radio-frequency electromagnetic radiation (RF-EMR) with the brain is a serious concern of our society. We evaluated the effect of RF-EMR from mobile phones on passive avoidance behaviour and hippocampal morphology in rats. Healthy male albino Wistar rats were exposed to RF-EMR by giving 50 missed calls (within 1 hour...

Chronic stress has been shown to cause oxidative damage in the central nervous system. Although stress-induced impairments in learning and memory have been studied extensively, very few studies have investigated possible ways to prevent their ill effects. The present work was designed to study the protective effects of ascorbic acid in memory loss...

The aim of this study was to compare the anti-arthritic activities of the plants Justicia gendarussa and Withania somnifera. Arthritis is induced in male albino rats using Freund′s complete adjuvant and bovine type II collagen. Leaves of J. gendarussa and roots of W. somnifera were powdered and extracted with ethanol (95%) using the soxhlet method....

INTRODUCTION With the tremendous increase in number of mobile phone users world wide, the possible risks of this technology have become a serious concern. OBJECTIVE We tested the effects of mobile phone exposure on spatial memory performance. MATERIALS AND METHODS Male Wistar rats (10–12 weeks old) were exposed to 50 missed calls/day for 4 weeks...

To evaluate the anti-arthritic potential of the plant Justicia gendarussa using two different rat models. The anti-arthritic potential of the alcoholic extract of the plant Justicia gendarussa was evaluated using the Freund's adjuvant-induced and collagen-induced arthritic rat models. The rats were treated with the ethanolic extract of Justicia gen...

Teachers often find it difficult to explain and convince first-year medical students about the different features and mannerisms associated with neurological disorders. For students, it's hard to visualize clinical cases without seeing the real patients in a clinical setup. Medical students here at

Ocimum sanctum plant extract was screened for its effects on restraint stress induced behavioral changes in Morris water maze and passive avoidance task. Restraint stress for 21 days caused memory impairment in rats. Animals treated with 100mg/kg body weight of Ocimum sanctum plant extract, by oral feeding during stress, showed a decreased latency...