Saravanan Durai

• M.sc., M.Phil., Ph.D
• Researcher at Sathyabama Institute of Science and Technology

The human microbiome, composed of billions of microorganisms residing in various bodily niches, is crucial to maintain good health and prevent diseases. Recent developments in nanotechnology have created new opportunities for comprehending, controlling, and utilizing the microbiome's potential. Nanotechnology can precisely manipulate microbial popu...

Alzheimer’s disease is the major cause of dementia, characterized by symptoms such as memory impairment and emotional disturbances. The association of TGFβ1 SNPs with Alzheimer’s disease has been reported in various studies but conflicting results were obtained worldwide. Hence, we have performed a meta-analysis of three SNPs in relationship with A...

The objective of this study was to develop nanobiomaterial containing silver nanoparticles (AgNPs) for wound healing. AgNPs were synthesized using Saussurea lappa (Sl) aqueous root extract as reducing agent and were characterized physico-chemically using UV-vis spectral studies, XRD, FESEM, TEM, FTIR spectral analysis, DLS, and TG-DSC. Sl AgNPs pro...

Concentrations of heavy metals namely Pb, Zn, Fe, Cu, Cd and Cr detected in tissue of two fish species (Pristipoma furcatus and Acanthurus strigosus) collected from Pulicate Lake, Chennai mixed with effluent from industries in and around north Chennai. The report shows significant results between the organs of P. furcatus and A. strigosus but also...

In the present study, aqueous and solvent extracts of leaves collected from nine mangrove plants were screened against Methicillin resistant Staphylococcus aureus (MRSA), Vancomycin resistant Staphylococcus aureus (VRSA) and Extended spectrum beta lactamase (ESBL) strains. Out of nine mangrove plants Avicennia sp., Rhizophora sp., Ceriops decandra...

The present study isolated plant growth promoting substance producing bacteria from Niligiri hills, Ooty, Tamilnadu. Totally 17 morpholigaclly different bacterial isolates were isolated. All the isolates were screened for plant growth promoting substances. Among 17 isolates, 5 (29.4%), 9(33.3%) and 11(40.7%) shows positive results for ammonia, acet...

Maximum antibiotics are produced by filamentous micro-organisms like, actinobacteria, fungi. In this study totally 15 fungi isolates were isolated from soil sample from Western Ghats forest. Out of 15 isolates 6 strains produce pigment and identified upto genus level. The strain MF5 showed best activity among other strains against test pathogens. T...

Maximum antibiotics are produced by filamentous micro-organisms like, actinobacteria, fungi. In this study totally 15 fungi isolates were isolated from soil sample from Western Ghats forest. Out of 15 isolates 6 strains produce pigment and identified upto genus level. The strain MF5 showed best activity among other strains against test pathogens. T...

The present study isolated plant growth promoting substance producing bacteria from Niligiri hills, Ooty, Tamilnadu. Totally 17 morpholigaclly different bacterial isolates were isolated. All the isolates were screened for plant growth promoting substances. Among 17 isolates, 5 (29.4%), 9(33.3%) and 11(40.7%) shows positive results for ammonia, acet...

The present study was attempted for Isolation and optimization of agarase producing bacteria from marine sources. Totally 12 morphologically different bacterial colonies were isolated from sediment collected from East coast of Pondicherry. All the isolates were screened for agarase activity by plate method. Among 12 strains E6 strain secrete maximu...

Phytochemical study and antimicrobial screening of Trigonella foenum graecum against diarrhoeal pathogens were carried out in this study. Diarrhoea causing bacteria Escherichia coli, Salmonella spp., Vibrio spp., and Shigella spp., was selected as test pathogens. Aqueous methanol and acetone extracts of Trigonella foenum graecum seeds were showed a...

The present study isolated dye degrading bacterial strain from textile effluent Kanchipuram, Tamilnadu. Totally 13 strains were isolated from the sample. Out of 13 bacterial isolates strain DD4 was selected as potent bacteria which degraded malachite green dye upto 10mg/100ml with 90.1% of decolourization. Strain DD4 showed, good degradation in pH...

In this present study, for the bioprospecting aspects, bacteria isolated from shoal forest soils, Western Ghats were explored. In total 32 bacteria was isolated and screened for biological activities. Out of 32 isolates, Enzymatic activities of bacterial isolates shows 62.5% positive for protease, 28.1% for amylase and glutaminase, 65.6% for urease...

In this present study, for the bioprospecting aspects, bacteria isolated from shoal forest soils, Western Ghats were explored. In total 32 bacteria was isolated and screened for biological activities. Out of 32 isolates, Enzymatic activities of bacterial isolates shows 62.5% positive for protease, 28.1% for amylase and glutaminase, 65.6% for urease...

Subcutaneous abscess is a very common clinical condition faced by guinea pigs, which is caused by the number of infective bacteria. Eight months old female guinea pig was presented with a firm circumscribed subcutaneous swelling on the left ventral aspect of the neck region. On physical examination the swelling was suggestive of abscess. Hematologi...

In the present study L-glutaminase producing bacteria were isolated from sediment samples collected from Mahabalipuram, Parangipettai and Sundarban mangrove ecosystems. L-glutaminase from selected 15 bacterial isolates was produced by submerged fermentation. Bacterial strain M9 isolated from Mahabalipuram marine sediments showed maximum L-glutamina...

This study was performed to isolate actinomycete colonies having antibacterial and antifungal activity from soil samples. A total of 27 actinomycete colonies were isolated in pure culture from five soil samples using Starch casein agar medium. Entire isolates were screened for their antimicrobial activity by agar plug method against five each of hu...

This study deals with bacterial prospecting from forest soil with special reference to antimicrobial substances. Total of 25 morphologically different bacterial colonies were isolated from soil samples collected from Anaimalai forest and Parambikulam tiger reserve forest, Western Ghats, India. About 12 (48%) out of 25 isolates showed antibacterial...

The present study was attempted for bioprospecting of pigmented marine Pseudoalteromonas species with special reference to enzymes. Totally 36 pigmented bacterial colonies were isolated from sediment and water samples collected from Pichavaram, Parangipettai and Muttukadu coastal areas and characterized. Based on the studied phenotypic characterist...

Marine fungi were isolated from sediment samples collected from Sundarban mangrove forest. Nine morphologically different fungal isolates were characterised and identified upto genus level. All the isolates belong in to the genus Aspergillus, Penicillium and Fusarium. Antibacterial activity of fungal isolates was tested against methicillin resistan...

The marine yeast strain SY3 was isolated from gut region of Lutjanus campechanus which is found to secrete inulinase in YPD medium. The partial purification of the enzyme by dialysis, showed over of 62.7U/ml of inulinase activity produced within 48 hours of fermentation in shake flask. The potential strain was identified as Cryptococcus sp based on...

In the present study, bioprospecting aspects of endophytic bacteria, isolated from leaves of 5 mangroves and 2 salt-marsh plant species, were explored. In total, 104 bacterial isolates were isolated from the leaf samples of mangrove plants of Pichavaram, Tamil Nadu. Thirty six fast growing isolates were selected and screened for biological activiti...