Sarah J White

• PhD
• Senior Researcher at University College London

Southgate et al.’s (Southgate 2007 Psychol. Sci. 18, 587-92 (doi:10.1111/j.1467-9280.2007.01944.x)) anticipatory-looking paradigm has presented exciting yet inconclusive evidence surrounding spontaneous mentalizing in autism. The present study aimed to develop this paradigm to address alternative explanations for the lack of predictive eye movement...

Human interaction is immersed in laughter; though genuine and posed laughter are acoustically distinct, they are both crucial socio-emotional signals. In this novel study, autistic and non-autistic adults explicitly rated the affective properties of genuine and posed laughter. Additionally, we explored whether their self-reported everyday experienc...

Spontaneous and conversational laughter are important socio-emotional communicative signals. Neuroimaging findings suggest that non-autistic people engage in mentalizing to understand the meaning behind conversational laughter. Autistic people may thus face specific challenges in processing conversational laughter, due to their mentalizing difficul...

One promising account for autism is implicit mentalizing difficulties. However, this account and even the existence of implicit mentalizing have been challenged because the replication results are mixed. Those unsuccessful replications may be due to the task contexts not being sufficiently evaluative. Therefore, the current study developed a more e...

Individuals with the fragile X premutation (FXP) are more likely to display elevated levels of autistic traits; however, these traits are not fully understood, and an underlying cause has not yet been studied. A reduction in spontaneous mentalizing has been found among other populations with high autistic traits, and it is widely accepted that this...

Background While most research on the non-verbal communication challenges encountered by autistic people centres on visual stimuli, non-verbal vocalizations remains overlooked. Laughter serves as a socio-emotional signal for affiliative bonding in interactions. Autistic people seem to experience and produce laughter differently to non-autistic peop...

Autistic adults struggle to reliably differentiate genuine and posed smiles. Intergroup bias is a promising factor that may modulate smile discrimination performance, which has been shown in neurotypical adults, and which could highlight ways to make social interactions easier. However, it is not clear whether this bias also exists in autistic peop...

One promising account for autism is implicit mentalizing difficulties. However, this account and even the existence of implicit mentalizing have been challenged because the replication results are mixed. Those unsuccessful replications may be due to the task contexts not being sufficiently evaluative. Therefore, the current study developed a more e...

The Frith–Happé Animations Test, depicting interactions between triangles, is widely used to measure theory of mind (ToM) ability in autism spectrum disorder (ASD). This test began with recording, transcribing, and subjectively scoring participants' verbal descriptions, which consistently found ToM-specific difficulties in ASD. More recently in 201...

Research learning communities (RLCs) are an increasingly popular form of collaborative professional development that takes participants into deep engagement with research evidence and empowers them to become researchers themselves. This study describes the use of the RLC model to make research about autism and school system change accessible to tea...

Background: Some autistic individuals with good compensatory skills may circumvent diagnosis, but still struggle with mentalizing. This missed or delayed identification can deprive them of the opportunity to receive necessary support and interventions. Thus, more sensitive assessment techniques are needed that are not susceptible to compensation. O...

Background Research on women with the fragile-X premutation (FX-p) has been underrepresented within the field of behavioural phenotypes. Aims To understand whether the FX-p confers risk for autistic traits, depression and anxiety, independent of maternal status. Method In study 1, mothers of children with fragile-X syndrome (M-FXp; n = 51, mean a...

Some people with autism spectrum disorders have been observed to experience difficulties with making correct inferences in conversations in social situations. However, the nature and origin of their problem is rarely investigated. This study used manipulations of video stimuli to investigate two questions. The first question was whether it is the n...

Autism Spectrum Condition (ASC) is a life-long diagnosis, which has a subset of features including hyper-, seeking- and/or hypo-reactivity to sensory inputs or unusual interests (APA, 2013). These qualities are evident across environmental (e.g. response to specific sounds, visual fascination with lights or movements) and physiological domains (e.g...

Animals and humans use a midbrain structure to coordinate and process relevant visual and auditory stimuli while suppressing distracting information. In modelling this assembly and managing both environmental and physiological stimuli using engineering principles, my research aspires to deep learning models that sense, categorize and alert autistic...

Autism Spectrum Condition (ASC) is a life-long diagnosis, which has a subset of individualized characteristics consisting of hyper-, seeking- and/or hypo-reactivity to sensory inputs or unusual interests (APA, 2013). These sensitivities are evident in both environmental (e.g. apparent response to specific sounds, visual fascination with lights or m...

Is Machine Learning/Deep Learning (ML/DL) a technological necessity when implementing SensorAble or is it something to be investigated because of its potential? Should ML/DL be implemented because it permits processing large quantities of multimodal data enabling modelling of autistic neurocognitive processes that well relate to distractibility and...

Animals and humans use a midbrain structure to coordinate and process relevant visual and auditory stimuli while suppressing distracting information. In modelling this assembly and managing both environmental and physiological stimuli using engineering principles, my research aspires to deep learning models that sense, categorize and alert autistic...

Autism Spectrum Condition (ASC) is a life-long diagnosis, which has a subset of features including hyper-, seeking- and/or hypo-reactivity to sensory inputs or unusual interests (APA, 2013). These qualities are evident across environmental (e.g. response to specific sounds, visual fascination with lights or movements) and physiological domains (e.g...

Laughter is a positive vocal emotional expression: most laughter is found in social interactions [1]. We are overwhelmingly more likely to laugh when we are with other people [1], and laughter can play a very important communicative role [2]. We do of course also laugh at humor — but can laughter influence how funny we actually perceive the humorou...

Autism Spectrum Condition (ASC) is a life-long diagnosis, which has a subset of individualized characteristics consisting of hyper-, seeking- and/or hypo-reactivity to sensory inputs or unusual interests (APA, 2013). These sensitivities are evident in both environmental (e.g. apparent response to specific sounds, visual fascination with lights or m...

Several theories have attempted to characterise autism spectrum disorders (ASDs) at the cognitive level, most notably: theory of mind (ToM), executive function (EF), and a local processing bias (LB). The aim of this study was to investigate how these cognitive functions develop over time The three cognitive domains (ToM, EF, and LB) were examined i...

Restricted and repetitive patterns of behaviours, interests, or activities are a critical diagnostic criterion for autism spectrum disorder (ASD). Previous studies using gambling paradigms with ASD populations have identified that, unlike typically developed control participants, people with a diagnosis of ASD tend to maintain particular response p...

Some children with high-functioning autistic spectrum conditions (ASC) have been noted clinically to produce accounts and responses akin to confabulations in neurological patients. Neurological confabulation is typically associated with abnormalities of the frontal lobes and related structures, and some forms have been linked to poor performance on...

The autism spectrum is characterized by genetic and behavioral heterogeneity. However, it is still unknown whether there is a universal pattern of cognitive impairment in autism spectrum disorder (ASD) and whether multiple cognitive impairments are needed to explain the full range of behavioral symptoms. This study aimed to determine whether three...

Reports of sensory disturbance, such as loudness sensitivity or sound intolerance, are ubiquitous in Autism Spectrum Disorder (ASD) but a mechanistic explanation for these perceptual differences is lacking. Here we tested adaptation to loudness, a process that regulates incoming sensory input, in adults with ASD and matched controls. Simple loudnes...

43 typically-developed adults and 35 adults with ASD performed a cartoon faux pas test. Adults with ASD apparently over-detected faux pas despite good comprehension abilities, and were generally slower at responding. Signal detection analysis demonstrated that the ASD participants had significantly greater difficulty detecting whether a cartoon dep...

In the director task (DT), participants are instructed to move objects within a grid of shelves while ignoring those objects that cannot be seen by a human figure, the "director," located beyond the shelves. It is widely assumed that, since they are explicitly instructed to do, participants use mentalizing in this communicative task; they represent...

Individuals on the higher-functioning end of the autism spectrum have significant impairments in communication. Language delay can occur, particularly in syntactic or structural linguistic knowledge. However, classically observed semantic deficits generally overshadow these structural deficits. This research examined the potential effects on compre...

Previous behavioral research suggests enhanced local visual processing in individuals with autism spectrum disorders (ASDs). Here we used functional MRI and population receptive field (pRF) analysis to test whether the response selectivity of human visual cortex is atypical in individuals with high-functioning ASDs compared with neurotypical, demog...

Some autistic children pass classic Theory of Mind (ToM) tasks that others fail, but the significance of this finding is at present unclear. We identified two such groups of primary school age (labelled ToM+ and ToM-) and a matched comparison group of typically developing children (TD). Five years later we tested these participants again on a ToM t...

Previous research has suggested that the local processing bias often reported in studies of Autism Spectrum Condition may only be typical of a subgroup of individuals with autism also presenting with macrocephaly. The current study examined a group of children with autism, with and without macrocephaly, on the Children's Embedded Figures Test (CEFT...

The executive dysfunction theory attempts to explain not only the repetitive behaviours but also the socio-communicative difficulties in autism. While it is clear that some individuals with autism perform poorly on certain executive function tasks, it remains unclear what underlies these impairments. The most consistent and striking difficulties ar...

Evidence for successful socio-cognitive training in typical adults is rare. This study attempted to improve Theory of Mind (ToM) and visual perspective taking in healthy adults by training participants to either imitate or to inhibit imitation. Twenty-four hours after training, all participants completed tests of ToM and visual perspective taking....

It is now widely accepted that individuals with autism have a Theory of Mind (ToM) or mentalizing deficit. This has traditionally been assessed with false-belief tasks and, more recently, with silent geometric animations, an on-line ToM task. In adults with milder forms of autism standard false-belief tests, originally devised for children, often p...

Reports of co-morbid symptoms of ADHD in children with ASD have increased. This research sought to identify ADHD-related behaviours in a sample of children with ASD, and their relationship with the ASD triad of impairments and related cognitive impairments. Children with ASD (n=55) completed a comprehensive cognitive assessment whilst a semi-struct...

The Embedded Figures Test assesses weak central coherence and individuals with autism are commonly assumed to perform superiorly; however, the evidence for this claim is somewhat mixed. Here, two large (N = 45 and 62) samples of high-functioning children (6-16 years) with autism spectrum disorder performed similarly to typically-developing children...

Individuals with autism spectrum disorders have highly characteristic impairments in social interaction and this is true also for those with high functioning autism or Asperger syndrome (AS). These social cognitive impairments are far from global and it seems likely that some of the building blocks of social cognition are intact. In our first exper...

Difficulties in social cognition are well recognized in individuals with autism spectrum conditions (henceforth 'autism'). Here we focus on one crucial aspect of social cognition: the ability to empathize with the feelings of another. In contrast to theory of mind, a capacity that has often been observed to be impaired in individuals with autism, m...

Face perception provides information critical to cognitive computations about the social world. This raises the possibility that the development of mechanisms used for social cognition may depend on the presence of normal face perception mechanisms, and this notion partly motivates an aetiological model of autism spectrum disorder (ASD) that sugges...

Adults with Asperger syndrome can understand mental states such as desires and beliefs (mentalizing) when explicitly prompted to do so, despite having impairments in social communication. We directly tested the hypothesis that such individuals nevertheless fail to mentalize spontaneously. To this end, we used an eye-tracking task that has revealed...

A test of advanced theory of mind (ToM), first introduced by F. Happé (1994), was adapted for children (mental, human, animal, and nature stories plus unlinked sentences). These materials were closely matched for difficulty and were presented to forty-five 7- to 12-year-olds with autism and 27 control children. Children with autism who showed ToM i...

The executive function (EF) theory of autism has received much support recently from a growing number of studies. However, executive impairments have not always been easy to identify consistently and so novel "ecologically valid" tests have been designed which tap into real-life scenarios that are relevant to and representative of everyday behavior...

Autism is thought to be associated with a bias towards detail-focussed processing. While the cognitive basis remains controversial, one strong hypothesis is that there are high processing costs associated with changing from local into global processing. A possible neural mechanism underlying this processing style is abnormal neural connectivity; sp...

Explaining and predicting behavior involves understanding others in terms of their mental states — the so-called Theory of Mind (ToM). It also involves the capacity to understand others in terms of culturally transmitted information about group membership, for example, which social groups exist in one's culture and which stereotypes adhere to these...

Does sensorimotor dysfunction underlie reading impairment? To investigate this question, a battery of literacy, phonology, auditory, visual, and motor tests were administered to age- and ability-matched groups of dyslexic, autistic, and control children. As in previous studies, only a subset of the dyslexic children had sensory and/or motor impairm...

We asked adults with Asperger Syndrome to judge pictorial stimuli in terms of certain social stereotypes to evaluate to what extent they have access to this type of social knowledge. Sixteen adults with Asperger Syndrome and 24 controls, matched for age and intelligence, were presented with sets of faces, bodies and objects, which had to be rated o...

This study attempts to investigate the role of sensorimotor impairments in the reading disability that characterizes dyslexia. Twenty-three children with dyslexia were compared to 22 control children, matched for age and non-verbal intelligence, on tasks assessing literacy as well as phonological, visual, auditory and motor abilities. The dyslexic...

Children with autistic spectrum disorder and controls performed tasks of coherent motion and form detection, and motor control. Additionally, the ratio of the 2nd and 4th digits of these children, which is thought to be an indicator of foetal testosterone, was measured. Children in the experimental group were impaired at tasks of motor control, and...

A multiple case study was conducted in order to assess three leading theories of developmental dyslexia: (i) the phonological theory, (ii) the magnocellular (auditory and visual) theory and (iii) the cerebellar theory. Sixteen dyslexic and 16 control university students were administered a full battery of psychometric, phonological, auditory, visua...

Social stereotypes provide a cognitively "inexpensive" if often inaccurate way to predict the behavior of others. We found that in spite of autistic children's profound impairment in the ability to predict behavior on the basis of an individual's mental state, they were just as likely as young normal children to use stereotypes to predict outcomes...