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6
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Introduction
Developing tissue engineered in vitro human vaginal models to test potential biomaterials for the repair of pelvic floor.
Pelvic floor regenerative medicine
Current institution
Publications
Publications (6)
Childbirth contributes to common pelvic floor problems requiring reconstructive surgery in postmenopausal women. Our aim was to develop a tissue-engineered vaginal wound model to investigate wound healing and the contribution of estradiol to pelvic tissue repair. Partial thickness scalpel wounds were made in tissue models based on decellularized sh...
Aims:
There are many situations where preclinical models of the human vagina would be valuable for in vitro studies into the pathophysiology of vaginally transmitted diseases, microbicide efficacy, irritability testing, and particularly, for assessing materials to be inserted in the vagina for support of the pelvic floor. The aim of this study is...
Aims:
Pelvic organ prolapse and stress urinary incontinence affect 40-50% of postmenopausal women worldwide. Polypropylene meshes have been extensively used for the surgical intervention of these disorders; however, these meshes can lead to severe complications in some patients. The need for synthetic materials more suited for use in pelvic floor...
In this study, the protease producing bacterium was isolated from chicken waste and characterized as Staphylococcus aureus through 16S rRNA ribotyping. The protease from S. aureus S-2 showed maximum activity of 360 U/mL. S. aureus S-2 showed optimum growth at 37°C and pH 7. S. aureus S-2 was able to grow in 1% gram pulse, mung beans and hydrolyzed...
Wheat bran, a by-product of wheat milling industry, is the outermost covering of wheat grain. It has relatively diverse application in food, feed, medicine and fermentation industries due to its richness in carbohydrates (mostly fibers), protein and fats which makes it an important dietary element. Its importance from medical view point is well doc...
The present study is aimed at assessing the ability of Bacillus subtilis to convert starch into reducing sugars. Maximum enzyme activity showed by B. subtilis was 236 Uml-1. B. subtilis showed optimum growth at pH 8 and optimum temperature for the growth of bacterial isolate was found to be 45°C. The optimal pH and temperature of the amylase activi...
