Sarah K. Giles

Sarah K. Giles
Flinders University · School of Biological Sciences

Doctor of Philosophy

About

7
Publications
1,589
Reads
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59
Citations
Citations since 2016
6 Research Items
57 Citations
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Introduction
Virome extractions: many people are looking at the microbiome and how this important microbial community affects our daily lives. But there is little to no research on the virome, the viruses that infect us. In particular the bacteriophage the live within us and have a lytic and or lysogenic relationship with our microbiome. These important and interesting interactions affect disease progression like cancer as well and recovery.

Publications

Publications (7)
Preprint
The gut virome is an incredibly complex part of the gut ecosystem. Gut viruses play a role in many disease 9 states, but it is not yet known to what extent the gut virome impacts everyday human health. New 10 experimental and bioinformatic approaches are required to address this knowledge gap. Gut virome 11 colonisation begins at birth, becoming te...
Article
Full-text available
Acinetobacter baumannii is an opportunistic human pathogen responsible for numerous severe nosocomial infections. Genome analysis on the A. baumannii clinical isolate 04117201 revealed the presence of 13 two-component signal transduction systems (TCS). Of these, we examined the putative TCS named here as StkSR. The stkR response regulator was delet...
Article
Background Most bacterial genomes contain integrated bacteriophages—prophages—in various states of decay. Many are active and able to excise from the genome and replicate, while others are cryptic prophages, remnants of their former selves. Over the last two decades, many computational tools have been developed to identify the prophage components o...
Article
Background Most bacterial genomes contain integrated bacteriophages—prophages—in various states of decay. Many are active and able to excise from the genome and replicate, while others are cryptic prophages, remnants of their former selves. Over the last two decades, many computational tools have been developed to identify the prophage components o...
Preprint
Full-text available
Most bacterial genomes contain integrated bacteriophages—prophages—in various states of decay. Many are active and able to excise from the genome and replicate, while others are cryptic prophages, remnants of their former selves. Over the last two decades, many computational tools have been developed to identify the prophage components of bacterial...
Article
Full-text available
Background Acinetobacter baumannii is an opportunistic pathogen, which has the ability to persist in the clinical environment, causing acute and chronic infections. A possible mechanism contributing to survival of A. baumannii is its ability to form a biofilm-like structure at the air/liquid interface, known as a pellicle. This study aimed to ident...

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Projects

Project (1)
Project
Virome extraction of cancer patients pre and post chemotherapy; Virome extractions of patients with ICP; Flow cytometry identification of the ESKAPE group of pathogens