Sarah Alharthi

• PhD in Chemistry
• Professor (Associate) at Taif University

A reversed-phase high-performance liquid chromatography (RP-HPLC) method was developed for simultaneous determination of triclabendazole (TCB) and ivermectin (IVM) in pharmaceutical dosage form. A mobile phase consisting of acetonitrile/water (50:50 v/v) with a flow rate of 1.5 mL/min was used for chromatographic separation of the mixture of TCB an...

Fluorescence‐based biosensors have become highly effective analytical instruments, revolutionizing the landscape of biological and chemical detection across diverse fields. These devices harness the unique properties of fluorescence to detect and quantify a wide array of analytes with remarkable sensitivity and specificity. By integrating biologica...

This study thoroughly examined the effects of soil treatments on the soil geotechnical properties and ginger rhizome oil quality. Ginger was cultivated in soil subjected to four different treatment plans: one with organic manure (ORG 1), another with combination of organic manure and seaweed extract (ORG 2), a third with the NPK 15:15:15 fertilizer...

The interest in using the Datura stramonium plant is due to its natural products, which are used in many pharmaceutical industries. The objective of the current study was to assess the therapeutic and cytotoxic effects of the D. stramonium plant on two types of human cancer cell models (MCF7 and HT29) in vitro. A soxhlet apparatus was used to obtai...

The presence of bisphenol A (BPA) in the environment is becoming an increasingly serious threat to human health, and its removal is crucial. In the current study, a novel adsorbent based on C18 functionalized silica-coated iron oxide nanoparticles (Fe3O4@SiO2-C18) was prepared for the adsorptive removal of BPA from water. First, magnetic Fe3O4 NPs...

This study has applied the density functional theory (DFT) to calculate the structural, magnetoelectronic, optical, and thermoelectric characteristics of Cs2XMoBr6 (X = Li, Na). The magnetic stability of studied compounds is examined by minimizing their total ground state energies. Also, both compounds exhibit cubic stability by tolerance factor as...

Mesoporous materials have garnered a lot of interest because of their porous structure, larger surface area and easy surface functionalization to incorporate functional group of choice. Herein, chiral mesoporous silica...

In this study, new monolithic poly(9-anthracenylmethyl methacrylate-co-trimethylolpropane trimethacrylate (TRIM) columns, referred as ANM monoliths were prepared, for the first time, and were used for the separation media for biomolecules and proteomics analysis by nano-liquid chromatography (nano-LC). Monolithic columns were prepared by in situ po...

This study investigates the magnetic, thermal, and electrical properties of Co 0.72 Sr 0.07 Ni 0.21 Fe 2 O 4 ferrite nanoparticles under different conditions, including as-prepared, irradiated (at a dose of 100 kGy in CO 2 atmosphere), and aged (at 1000°C). The magnetic properties are analyzed using M-H loops, revealing that the aged sample exhibit...

Water is a fundamental resource, yet various contaminants increasingly threaten its quality, necessitating effective remediation strategies. Sustainable polymeric adsorbents have emerged as promising materials in adsorption-based water remediation technologies, particularly for the removal of contaminants and deactivation of water-borne pathogens....

Rapidly developing two-dimensional (2D) materials, such as MoS2, graphene, and other transition metal dichalcogenides (TMDCs), have opened new possibilities for biosensing technologies. These materials exhibit unique electrical, mechanical, and optical properties, making them ideal candidates for highly sensitive and selective biosensors. This revi...

Gold nanoclusters (AuNCs), with sizes below 2 nm, have emerged as remarkable nanomaterials exhibiting unique optical, electronic, and chemical properties. Their ultra-small size imparts advantageous characteristics, including high surface area, tunable fluorescence, and excellent biocompatibility, making AuNCs highly promising for diverse applicati...

Antibacterial resistance requires an advanced strategy to increase the efficacy of current therapeutics in addition to the synthesis of new generations of antibiotics. In this study, copper oxide nanoparticles (CuO-NPs) were green synthesized using Moringa oleifera root extract. CuO-NPs fabricated into a form of aspartic acid-ciprofloxacin-polyethy...

A number of obstacles, including irrigated wastewater and soil contamination, arise in the growth of aromatic and medicinal plants. This study aimed to reduce the effects of contaminated soil and wastewater irrigation on rosemary (Rosmarinus officinalis L.) plants by using biosynthesized silver nanoparticles (AgNPs) produced by the ginger (Zingiber...

The effects of some innovative antibacterial and antifungal coating films of chitosan/nano zinc oxide/essential oil (C-ZNO-EO) on grape preservation for human health were studied during the storage periods on (0, 4, 7, 14, and 16) days. Several evaluation approaches were evaluated such as the bacterial evaluations against the presence of the mesoph...

In the present work, an efficient isocratic HPLC method was developed for the precise and accurate estimation of vitamin D3 in tablet form. The chromatographic conditions comprised an L3 silica column (5 µm in particle size, 4.6 mm × 250 mm) with a mobile phase n-hexane/ethyl acetate (85:15 v/v) with a flow rate of 2.0 mL/min and a detection wavele...

The perilous increase of Pseudomonas aeruginosa resistance and its great ability to produce several vir-ulence factors is an emergent global health problem. Further investigation and docking study were further performed to predict the ideal identified compounds of propolis ethanolic extract with high affinity to interact with some selected virulenc...

The contamination of freshwater bodies via inappropriately released wastewater can be effectively prevented using membrane separation methods at the point of industrial discharge. Graphene oxide (GO), an allotrope of carbon, has adjustable physicochemical characteristics and a lot of potential for environmental cleanup. Due to its narrow and variab...

This study explores the transformative impact of the innovative surface nano zinc oxide coatings on grapes, emphasizing their influence on postharvest attributes, phytochemical composition, and fungal population. Distinct coating formulations, including distilled water (Control), chitosan (C), chitosan-nano zinc oxide (C-NZO), and chitosan-nano zin...

Miniaturized-LC has become a primary tool in sensitive protein separation for gaining an understanding of complex biological processes. In recent decades, significant advances have been achieved in nanoscale separations. The protein analysis platforms still need to develop in order to increase the overall sensitivity in proteomics applications. In...

In the twenty-first century, a key focus is the search for materials that hold promise for energy generation and storage. Solar energy, with its abundant availability and minimal impact on the environment, stands out as one of the most important renewable energy sources. Metal halide perovskites have emerged as a fascinating group of materials that...

The goal of this study is to draw attention to the vital nutrients, health advantages, and potential for encouraging the consumption of jamun fruits (Syzygium cumini L.) and making the most of their useful features to create valuable goods. In the current study, efforts have been made to evaluate the jamun fruit’s physicochemical characteristics an...

Cadmium (Cd) is one of the most hazardous metals to the environment and human health. Neurotoxicity is of the most serious hazards caused by Cd. Mirtazapine (MZP) is a central presynaptic α2 receptor antagonist used effectively in treating several neurological disorders. This study investigated the anti-inflammatory and antioxidant activity of MZP...

The utilization of biochar, derived from agricultural waste, has garnered attention as a valuable material for enhancing soil properties and serving as a substitute adsorbent for the elimination of hazardous heavy metals and organic contaminants from wastewater. In the present investigation, amide-modified biochar was synthesized via low-temperatur...

Electrolytes are one of the most influential aspects determining the efficiency of electrochemical supercapacitors. Therefore, in this paper, we investigate the effect of introducing co-solvents of ester into ethylene carbonate (EC). The use of ester co-solvents in ethylene carbonate (EC) as an electrolyte for supercapacitors improves conductivity,...

Recently, great efforts have been made to develop materials based on magnetic metal oxides to realize excellent electromagnetic wave absorption properties. Nevertheless, the use of traditional magnetic metal oxide materials with certain magnetic losses is not only difficult to meet the final requirements, but also limits the thickness of the absorb...

Arsenic (As3+) is the most carcinogenic and abundantly available heavy metal present in the environment. Vertically aligned ZnO nanorod (ZnO-NR) growth was achieved on metallic nickel foam substrate via a wet chemical route and it was used as an electrochemical sensor towards As(iii) detection in polluted water. Crystal structure confirmation, surf...

In the present work, several properties of fluoroperovskites are computed and examined through the approximations of trans- and blaha-modified Becke–Johnson (TB-mBJ) and generalized gradient approximation of Perdew–Burke–Ernzerhof (GGA-PBE) integrated within density functional theory (DFT). The lattice parameters for cubic TlXF3 (X = Be, Sr) ternar...

In this work, the new compositions of FeCoNiAlMn 1−x Cr x , (0.0 ≤ x ≤ 1.0), a high-entropy alloy powder (HEAP), are prepared by mechanical alloying (MA). The influence of Cr doping on the phase structure, microstructure, and magnetic properties is thoroughly investigated through X-ray diffraction (XRD), scanning electron microscopy (SEM), and vibr...

The increasing research of advanced materials with tremendous compositional and structural degrees of variation, identifying and discovering new materials for a specific application is a challenging task. Here, we report for the first time the predicted structural, optoelectronic, and mechanical properties of germanium based AGeF3 (A = Ga and In) h...

While clay has been extensively studied for its ability to remove chlorophyll from vegetable oil, its effects and suitability on microalgae oil have received far less attention. In this study, three different clay types are evaluated and compared for their ability to dechlorophyllise microalgae oil. The clays involved are kaolinite, Fuller’s earth...

Monolithic poly(2-vinylnaphthalene-co-divinylbenzene) columns were introduced, for the first time, and were evaluated as the separation media for nano-liquid chromatography (nano-LC). These columns were prepared by in-situ polymerization of 2-vinylnaphthalene (2-VNA) as the functional monomer and divinylbenzene (DVB) as the crosslinker in a fused s...

Juglans regia Linn. is a valuable medicinal plant that possesses the therapeutic potential to treat a wide range of diseases in humans. It has been known to have significant nutritional and curative properties since ancient times, and almost all parts of this plant have been utilized to cure numerous fungal and bacterial disorders. The separation a...

In this study, novel open‐tubular nano‐columns with highly hydrophobic stationary phase were prepared via the surface graft polymerization of polyhedral oligomeric silsesquioxane‐methacrylate and 2‐vinylnaphthalene in a narrow capillary (i.e., 20 μm i.d.. In this preparation, polyhedral oligomeric silsesquioxane‐methacrylate was used as a reactive...

Microalgae farming is still in its infancy phase to implement internet-of-things (IoT) technologies. Spirulina microalgae was selected to be investigated in this study because it is the most commercially viable microalgae for large-scale production. There are various methods to measure the biomass concentration of microalgae. However, the conventio...

Develo...

The double perovskites (DPs) halides are outstanding materials for solar cells and thermoelectric applications. Therefore, here we have studied the electronic, optoelectronic, and thermoelectric properties of Rb2CuSbX6 (X = Cl, Br, I) by density functional theory. Thermodynamic and structural stabilities are validated by evaluating the enthalpy of...

Medicinal plants play important role in the public health sector worldwide. Natural products from medicinal plants are sources of unlimited opportunities for new drug leads because of their unique chemical diversity. Researchers have focused on exploring herbal products as potential sources for the treatment of cancer, cardiac and infectious diseas...

1,3,4-Thiadiazole molecules (1-4) were synthesized by the reaction of phenylthiosemicarbazide and methoxy cinnamic acid molecules in the presence of phosphorus oxychloride, and characterized with UV, FT-IR, 13C-NMR, and 1H-NMR methods. DFT calculations (b3lyp/6-311++G(d,p)) were performed to investigate the structures' geometry and physiochemical p...

Magnesium-based spinel chalcogenides are remarkable materials for spintronic and energy harvesting applications. Therefore, the electronic, ferromagnetism, and thermoelectric characteristics of MgFe2(S/Se)4 spinels are addressed comprehensively by modified Becke Johnson potential (TB-mBJ). The stability of cubic phase has been illustrated by format...

Peptides and proteins have great therapeutic potential, and owing to their unique biological properties, their separation is very challenging. A polar embedded C18 stationary phase was prepared by functionalization of porous silica monolith particles with N-3-(trimethoxysilyl) propyl stearamide. The stationary phase was packed in narrow bore column...

The current work is aimed at isolating and identifying new Entomopathogenic bacterium (EPB) strains associated with Steinernema feltiae and assessing the EPB’s biocontrol potential on Aphis punicae and Aphis illinoisensis adults in the laboratory. From S. feltiae, five bacterial isolates were isolated and molecularly characterized. Lysinibacillus x...

Chemotherapy is an aggressive form of chemical drug therapy aiming to destroy cancer cells. Adjuvant therapy may reduce hazards of chemotherapy and help in destroying these cells when obtained from natural products, such as medical plants. In this study, the potential therapeutic effect of Rosa damascena callus crude extract produced in vitamin-enh...

The rose aphid Macrosiphum rosae (L.) is now a globally spread insect species damages rose plants affecting quality and productivity. Botanical insecticides are excellent alternative to synthetic pesticides, as they have minimal environmental persistence and toxicity, and are more compatible with the biocontrol agents than synthetic pesticides. Thi...

Aphids are serious pests of a wide range of agricultural crops, including pomegranates and grapevines. In addition, due to the negative environmental impacts of chemical insecticides, these pests are developing important resistance against aphicides. Therefore, one alternative method to control aphids is the use of essential oils (EO). The present...

Among the Mediterranean aromatic plants, Ruta tuberculata Forssk. (Rutaceae) has been widely used as a traditional natural remedy against various disorders resulting from its divers’ pharmacological virtues. The aim of this study is to characterize for the first time the phenolic profile of its ethyl acetate (EtOAcE) and acetonic (AcE) extracts and...

Vacancy-ordered double perovskites have been studied vastly for energy applications for the last few decades. In this article, we have investigated the optical and thermoelectric characteristics of Ga2TiX6 (X = Cl, Br, I). The phonons dispersions, formation energy, and tolerance factors reveal dynamic and structural stabilities. The predicted band...

The perennial aromatic plant Ruta tuberculata Forssk (Rutaceae) has been traditionally used by Mediterranean peoples as folk medicine against several types of disease to treat diverse illness. The objective of this work is to evaluate the in vitro and in vivo pharmacological activities of the aqueous (RAE) and methanolic (MeOH) 80% (RME) extracts o...

Semiconductor-based photocatalytic technology is regarded as an efficient pathway for resolving the energy scarcity across the globe. In this regard, graphitic carbon nitride (g- C3N4)-based materials could be alternatively employed in photochemical applications such as photovoltaic energy generation via CO2 photoreduction and water splitting, alon...

The double perovskites have emerging optical properties and extensively studied solar cells and renewable energy. In this work, we have investigated the optical, electronic and transport properties of Cs2KTlX6 (X = Cl, Br, I) using density functional theory. The thermodynamic stability is determined from the calculation of enthalpy of formation and...

Separation with high efficiency and good resolution is constantly in demand in the pharmaceutical industry. The fast and efficient separation of complex samples such as peptides and proteins is a challenging task. To achieve high efficiency with good resolution, chromatographers are moving towards small particles packed into narrow-bore columns. Si...

Exposure to cadmium chloride (CdCl2) causes an imbalance in the oxidant status of the body by triggering the release of reactive oxygen species (ROS). This study investigated the effect of Rosa damascena (R. damascena) extract on oxidative stress, hepatotoxicity, and the injured cardiac tissue of male rats exposed to CdCl2. Forty male Wistar albino...

Methyl violet 2B dye is a major contaminant that is detrimental to both humans and aquatic microorganisms, thus it should be eliminated from water. In the current investigation, the biosorption of methyl violet 2B dye onto the brown seaweed Cystoseira tamariscifolia biomass as a sustainable low-cost biosorbent was examined by varying biosorption pa...

The double perovskites (DPs) have recently been realized as emerging materials in the field of optoelectronics owing to their remarkable and diverse electronic, optical, thermoelectric, and mechanical properties. Herein, we have comprehensively investigated some of the narrow bandgap DPs for instance; Ba2InBiO6, Ba2TlSbO6, and Sr2TlBiO6 based on DF...

Porous silica particles were prepared by sol–gel method with some modification to get wide-pore particles. These particles were derivatized with N-phenylmaleimide-methylvinylisocyanate (PMI) and styrene by reversible addition fragmentation chain transfer (RAFT) polymerization to prepare N-phenylmaleimide embedded polystyrene (PMP) stationary phases...

The release of effluents containing cadmium ions into aquatic ecosystems is hazardous to humans and marine organisms. In the current investigation, biosorption of Cd2+ ions from aqueous solutions by freely suspended and immobilized Turbinaria ornata biomasses was studied. Compared to free cells (94.34%), the maximum Cd2+ removal efficiency reached...

Simple Summary For sustainable agriculture, there is a need to identify and evaluate more biocontrol agents, including entomopathogenic nematodes (EPNs). In this study, EPNs and their associated entomopathogenic bacteria symbionts (EPBs) were isolated and identified from 320 soil samples collected in Taif, Saudi Arabia. The biocontrol efficacy of E...

A new and valid method was developed for the quantitative voltammetric analysis of midodrine hydrochloride (MID) in pharmaceutical tablets (Midodrine) and biological samples. The method is based on electro-oxidation of MID supported by both disposable pencil electrode (PE) and glassy carbon electrode (GCE). The analysis was carried out using cyclic...

A simple, accurate and fast method was developed for the assessment of 3-nitrotyrosine as a biomarker for the early diagnosis of liver cirrhosis with minimal hepatic encephalopathy (MHE) using a (Eu(TTA)3Phen) photo probe. 3-Nitrotyrosine can remarkably quench the luminescence intensity of the (Eu(TTA)3Phen) complex in DMSO at pH = 9 and λem = 617...

The charge and spin degrees of freedom of electrons employed together introduce a new field of electronics, known as spintronics, which has multifunctional applications in data storage, control, and transfer in supercomputing. In this perspective, we have comprehensively investigated cubic double perovskites Rb2Z(Cl/Br)6 (Z = Ta, W, Re). More preci...

In this study, a novel narrow capillary (i.e., 20 µm i.d.) coating procedure was reported for the preparation and application of open-tubular (OT) column for the separation of casein (CN) protein variants in milk. Based on this approach, a new poly-L-lysine (PLL) grafted on graphene oxide stationary phase was developed for OT nano-liquid chromatogr...

The stainless steel waste solutions, produced during the electroplating process, were found to contain high chromium content (43.52 g/L). To avoid environmental chromium contamination and chromium toxicity, these wastes must be treated. In this work, new surface‐modified porous poly‐2‐((methacryloxy)‐methyl)‐oxirane polymers were synthesized, chara...

In the current research the functional and value added macaroni was prepared with fortification of lentil, millet, and white rice flour as ingredients with wheat semolina. The proximate composition, physico-chemical analysis such as phenolic content, flavonoid content and antioxidant activity of the raw materials were investigated. The cooking qual...

Air Frying technology is an innovative technique which could produce healthy fried food materials using hot air. The current work aimed to model the kinetic changes in mass transfer, texture and colour attributes and determining the temperature dependency of the rate constants of the mass transfer, texture and colour traits of the air-fried falafel...

This study focused on the quality, chemical composition, microbiological population, and sensory assessments of stored mackerel fish products such as bouillon and sauce during the cold storage (4 °C) condition throughout the 12 month of storage period. The fish contains appreciable amounts of moisture content (71.33 g/100 g), protein content (22.55...

Fabrications of new mesoporous silica adsorbents for radioactive element removal/recovery are of economic and environmental concern. Herein, a mesoporous monolithic cage of phosphonate functionalized silica (MMCS@phosphonate) was synthesized and applied for Th(IV) removal from an aqueous solution. The results demonstrate that Th(IV) adsorption is r...

A new bipyridine-containing manganese (II) complex, namely [(BPy)2MnCl2]·0.5H2O (MnC), was synthesized and characterized. Spectral and X-ray structural features revealed that MnC has an octahedral environment around Mn(II). Graphene oxide (GO) was noncovalently functionalized with the MnC. MnC- and (MnC/GO)-modified glassy carbon (GC) interfaces wi...