Sara Maldonado-Martin

• Physical Activity and Sport Sc
• Professor at University of the Basque Country

Introduction Bipolar disorder (BD) is associated with considerable morbidity and premature mortality, mainly due to somatic causes. This study aims to determine some physical, exercise capacity–related physiological variables and biochemical markers of health status in adults (45.4 ± 13.1 years) with BD (n = 65) compared to a healthy control (HC) p...

Background Around 40% of people with major depressive disorder (MDD) experience moderate remission, with the remainder meeting the criteria for resistant major depression (RMD). It has been shown that exercise has a low-to-moderate effect on MDD, but there is a lack of evidence on exercise interventions in RMD patients. The primary purpose of the p...

Background The objective of this systematic review was to analyze the effects of physical activity (PA) intervention as an adjuvant strategy to pharmacological treatment in people with treatment-resistant depression (TRD) and non-remitted depression (NRD). Methods A search strategy was realized from five databases: PubMed, Cochrane Central Register...

Cardiovascular events are positively associated with primary hypertension (HTN), obesity, and low cardiorespiratory fitness (CRF) and negatively with healthy dietary patterns, such as Healthy Diet Indicator (HDI), Mediterranean diet (MD), and the Dietary Approaches to Stop Hypertension (DASH). The aim is to analyze the association between healthy d...

Background Determinants of coronary artery disease, such as endothelial dysfunction and oxidative stress, could be attenuated by high-intensity aerobic interval exercise training (HIIT). However, the volume of this type of training is not well established. Objective To assess the impact of two volumes of HIIT, low (LV-HIIT, <10 min at high intensi...

Background The objective of this systematic review was to analyze the effects of the physical activity (PA) intervention as an adjuvant strategy to pharmacological treatment in people with treatment-resistant depression (TRD) and non-remitted depression (NRD). Methods A search strategy was realized from five databases: PubMed, Cochrane Central Regi...

Background The objective of this systematic review was to analyze the effects of the physical activity (PA) intervention as an adjuvant strategy to pharmacological treatment in people with treatment-resistant depression (TRD) and non-remitted depression (NRD). Methods A search strategy was realized from five databases: PubMed, Cochrane Central Reg...

Background Around 40% of people with major depressive disorder (MDD) experience moderate remission, with the remainder meeting the criteria for resistant major depression (RMD). It has been shown that exercise has a low-to-moderate effect on MDD, but there is a lack of evidence on exercise interventions in RMD patients. The primary purpose of the p...

Objective To determine the changes in health‐related quality of life (HRQoL) and sleep quality following a supervised combined exercise (EX) program compared to a Treatment‐As‐Usual (TAU) and to analyze the relationship between the differences in cardiorespiratory fitness (CRF) and HRQoL domains in people with schizophrenia (SZ). Methods The SZ (n...

Background The objective of this systematic review was to analyze the effects of the physical activity (PA) intervention as an adjuvant strategy to pharmacological treatment in people with treatment-resistant depression (TRD) and non-remitted depression (NRD). Methods A search strategy was realized from five databases: PubMed, Cochrane Central Regi...

This study aimed to investigate the applicability of the Lactate Threshold (LT) to predict maximal oxygen uptake (V̇O2max) and demarcate the boundary between the moderate- to heavy-intensity domain (HRm-h) in old age in comparison to the most utilized methods. A cross-sectional validation study was conducted. Participants aged 61 to 77 performed a...

Background The objective of this systematic review was to analyze the effects of the physical activity (PA) intervention as an adjuvant strategy to pharmacological treatment in people with treatment-resistant depression (TRD) and non-remitted depression (NRD). Methods A search strategy was realized from five databases: PubMed, Cochrane Central Reg...

Background Unilateral and bilateral peripheral vestibular hypofunction (UVH and BVH) often complains of dizziness, gaze, and balance disturbances. There is a lack of evidence on exercise intervention in UVH and BVH patients. To investigate the effect of an eight-week supervised multicomponent exercise program in people suffering from UVH or BVH in...

Purpose The relationship between exercise and its role in mental health is extensively documented and has led to the inclusion of exercise into adjuvant programs for people with mental health disorders. However, considerably less attention is devoted to the experience of taking part in exercise and perceived health outcomes for people with specific...

Purpose Bipolar disorder (BD) is a mental illness involving mood disorder, characterized by alternating normal mood, manic and depressive symptom. People with BD are associated with an unhealthy lifestyle. Assessment of cardiorespiratory fitness (CRF) indicates the overall health and can be directly measured and assessed by the cardiopulmonary exer...

Purpose People with schizophrenia (SP) in addition to presenting an unhealthy lifestyle, psychosocial determinants, such as decreased self-esteem and social stigma, and the presence of psychiatric symptoms, have a profound impact on the health-related quality of life (HRQoL). Thus, people with SP have reported greater disability than those healthy...

Purpose Treatment-resistant depression (TRD) is defined as those who do not remit to major depressive disorder with pharmacological treatment. TRD is associated with a worse health-related quality of life (QoL). Thus, people with TRD have reported greater disability than those healthy control (HC) in QoL, assessed by the 36-Item Short-Form Health S...

Introduction: Given the health benefits and the role of exercise as an anti-inflammatory adjuvant program, this study aimed to determine the effectiveness of a combined exercise program on cardiorespiratory fitness (CRF), body composition, and biochemical levels in adults with schizophrenia (SZ) characterized at baseline as metabolically unhealthy...

The aim of this study was to investigate the subjective experiences of a concurrent exercise program designed to improve both physical and mental health, through participation, for people with schizophrenia. Participants diagnosed with schizophrenia (n = 35, 41.6 ± 10.3 years) received an intensive concurrent exercise program for a 5-month duration...

Background Aerobic high-intensity interval training (HIIT) has demonstrated benefits for ventricular remodeling after myocardial infarction (MI) through various mechanisms. Despite this, the optimal training volume is not well known. The present study aimed to assess the effects of different (low vs. high volume) aerobic HIIT compared to an attenti...

Tabako-ohiturak gaixotasun kroniko gehienak pairatzeko arriskua areagotu dezakeen zabaldutako aztura da. Hauen artean, hipertentsioaren eragilea izan daitekeela behatu da. Honez gain, jarduera fisikoarekiko (JF) tolerantzian eta bihotz-biriketako funtzioan eragin kaltegarria izan dezake. Izan ere, JF-ak arrisku hauen garapena murriztu ditzake, biho...

Introduction Cardiorespiratory fitness (CRF) can be directly measured and assessed by the cardiopulmonary exercise test (CPET) or estimated from different field tests as the Modified Shuttle Walking Test (MSWT). The CRF in schizophrenia (SP) population may be altered due to sex, age, body composition and core symptoms variables. However, the extent...

Importance: The apparent cardioprotective effects of endogenous estrogens to prevent cardiovascular disease in premenopausal women are reduced with the loss of estrogen post-menopause. Cardiorespiratory fitness and cardiovascular risk factors are closely related to physical activity levels. Objective: This study conducted a critical assessment o...

Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Instituto de Salud Carlos III Background Bipolar disorder (BD) is a mental illness in which manic and depressive episodes are combined. People with BD are associated with an unhealthy lifestyle. Assessment of cardiorespiratory fitness...

Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Spanish Ministry of Economy and Competitiveness “Fondo de Investigación Sanitaria del Insti-tuto de Salud Carlos III” Background Individuals with schizophrenia (SP) have a greater risk for cardiometabolic risk factors, cardiovascular d...

Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Spanish Ministry of Economy and Competitiveness “Fondo de Investigación Sanitaria del Insti-tuto de Salud Carlos III” Background Concurrent training (i.e. a combination of aerobic and resistance exercise in the same session) is emergin...

This study aims to determine the impact of 2 (low vs high volume) high-intensity interval training (HIIT) programs with Mediterranean diet (MedDiet) recommendations on health-related quality of life (HRQoL) and lifestyle modification, and to examine the relationships between the changes in anxiety and depression with HRQoL and lifestyle variables a...

Background Physical inactivity and sedentary behavior are increasingly common problems in the general population, which can lead to overweight, obesity, diabetes, cardiovascular disease, and decreased motor and cognitive capacity among children and adolescents. Establishing healthy habits in childhood on the basis of the World Health Organization’s...

El presente trabajo recoge la experiencia y los principales resultados de la participación en el proyecto Global Matrix 4.0 de Euskadi, un proyecto liderado por el Gobierno Vasco, y con la participación de las tres Universidades Vascas: Universidad del País Vasco (UPV/EHU), Universidad de Deusto (Deusto) y Mondragón Unibertsitatea (MU). Este proyec...

Cardiorespiratory fitness (CRF) can be direct or estimated from different field tests. The Modified Shuttle Walk Test (MSWT) is suitable for all levels of function, allowing a peak response to be elicited. Therefore, we aimed (1) to validate the equation presented in the original study by Singh et al. for evaluating the relationship between MSWT wi...

BACKGROUND Physical inactivity and sedentary behavior are increasingly common problems in the general population, which can lead to overweight, obesity, diabetes, cardiovascular disease, and decreased motor and cognitive capacity among children and adolescents. Establishing healthy habits in childhood on the basis of the World Health Organization’s...

Purpose: The objectives of this study were to compare the effects of two different high-intensity interval training (HIIT) programs (low-volume vs high-volume) on chronotropic responses during exercise and recovery, and to contrast the results of the HIIT groups together to only physical activity recommendations in post-myocardial infarction (MI)...

Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): University of the Basque Country OnBehalf GIKAFIT PURPOSES. To analyse the change on leptin, body composition, blood pressure (BP), cardiorespiratory fitness (CRF) and some biochemical parameters in physically inactive women and men with primary hypert...

Primary hypertension (HTN) and obesity are associated with a worse health-related quality of life (QoL). This research was carried out to analyze the health-related QoL measurements in a physically inactive and obese population with HTN (n = 253) in comparison to a HEALTHY sample (n = 30), to determine the HTN sample changes in QoL following differ...

Schizophrenia (SP) is a severe mental illness with high rates of premature morbidity and mortality, associated with an unhealthy lifestyle and the side effects of drug treatment. The aims of the study were: 1) to determine some key physical, physiological and biochemical markers of health status, including sleep quality, in adults (42±10 yr) with S...

Introduction: Recent studies have shown that symptoms of psychiatric illness, functionality, and cognitive function improve with exercise. The aim of this study will be to investigate whether the implementation of an individualized exercise program will improve the functional status of patients with bipolar disorder (BD). Methods: This longitudinal...

The aims of the present study were to analyze the effects of 16 weeks of different aerobic exercise training (ExT) programs with diet on cardiac autonomic modulation and hemodynamics in nonphysically active and overweight/obese adults (n = 249, 53.7 ± 8.0 years) with primary hypertension, and the possible differences among ExT programs and their ef...

Background: The purposes of the study were to: analyze, by objective (accelerometry) and subjective (International Physical Activity Questionnaire, IPAQ) methodologies, the physical activity (PA) and sedentary behavior (SB) in healthy adults (HEALTHY, n = 30) and individuals with primary hypertension (HTN) and overweight/obesity (n = 218); assess...

How exercise intensity targets, calibrated according to oxygen consumption, relate to vertical impacts during weight-bearing exercise is currently unknown. The authors investigated the relationship between vertical peaks (VPs) and metabolic equivalents (METs) of oxygen consumption in 82 women during walking and running. The magnitude of VPs, measur...

Background Cardiovascular disease (CVD) is the most common cause of death in people with schizophrenia (SP). The European guidelines on CVD prevention recommend that people with high levels of individual risk factors should automatically have all their risk factors actively managed. It is suggested that CVD risk in SP should be assessed by general...

Metabolically unhealthy obesity (MUO) is a regular state in people with primary hypertension (HTN), obesity, and who are physically inactive. To achieve and maintain a metabolically healthy overweight/obese (MHO) state should be a main treatment goal. The aims of the study were (1) to determine differences in metabolic profiles of overweight/obese,...

Purpose The aim of this study was to analyze actigraphy-based sleep quantity and quality in sedentary and overweight/obese adults with primary hypertension (HTN) divided by sex and cardiorespiratory fitness (CRF) and to assess the association of sleep parameters with body composition, blood pressure (BP), and CRF. Methods This is a cross-sectional...

Purpose: To determine whether improvements in cardiorespiratory fitness (CRF), blood pressure (BP) and body composition previously seen after a 16-week exercise intervention (POST) with hypocaloric diet are maintained following six months (6M) of unsupervised exercise time. Methods: Overweight/obese, physically inactive participants with primary hy...

This study assessed gross efficiency (GE) during a single competitive season and determined the relationship between GE and maximum oxygen uptake (V̇O 2max ) in young elite cyclists (n = 15, 20.1 ± 1.4 yrs, 177.5 ± 5.7 cm, 68.3 ± 6.2 kg, 45.2 ± 7.5 mm of six skinfolds) during a competitive season. Participants completed at two occasions (T1 = April...

Purpose: The aim of this study was to compare the widely used accelerometer activity cut-points derived from the absolute moderate intensity recommendation (3‒6 METs), with relative intensity cut-points according to maximal cardiorespiratory fitness (46%‒63% V˙O2max) and to individual lactate thresholds (LT1 and LT2) in postmenopausal women. Method...

El objetivo del artículo es comparar la efectividad del Stretching Global Activo (SGA) con los estiramientos analíticos (EA) en personas mayores de 55 años. Se plantea un estudio aleatorio con dos grupos paralelos (SGA, n = 10 vs. EA, n = 12), con participantes mayores de 55 años, que tuvieron los siguientes criterios de exclusión: patología del ra...

Quevedo-Jerez, K, Gil-Rey, E, Maldonado-Martín, S, and Herrero-Román, F. Exercise-intensity adherence during aerobic training and cardiovascular response during resistance training in cancer survivors. J Strength Cond Res 35(8): 2338-2345, 2021-Combined aerobic-resistance training has shown the best benefits has proved beneficial for cancer survivo...

This study aimed to estimate the maximal lactate steady-state velocity (vMLSS) from non-invasive bloodless variables and/or blood lactate-related thresholds (BLRTs) measured during an Incremental submaximal Shuttle Test (IST), and to determine whether the addition of a Constant Velocity Test (CVT) could improve the estimation. Seventy-five postmeno...

Guía desarrollada por ASAFIMA (Asociación Alavesa de Fibromialgia y Síndrome de Fatiga Crónica) y la Facultad de Educación y Deporte-Sección CC de la Actividad Física y del Deporte (UPV/EHU) Esta guía está dividida en dos partes claramente diferenciadas; la primera presenta la evidencia científica del beneficio que cualquier tipo de actividad físic...

Cardiorespiratory fitness (CRF) is positively associated with enhanced cardiovascular health. This cross-sectional study aimed to determine associations between CRF and the biochemical profile of overweight/obese adults diagnosed with primary hypertension (HTN). Does cardiorespiratory fitness (exposure) positively affect the biochemical profile (ou...

Objectives: To investigate how objectively measured physical activity (PA) levels differ according to absolute moderate intensity recommendation (3–6 METs) and relative to individual lactate thresholds (LT1 and LT2), and to verify if highfit women record higher PA levels compared to women with lower aerobic fitness. Methods: Seventy-five postmenopa...

Introduction The EXERDIET-HTA study was a multi-arm parallel, a randomized, single-blind controlled experimental trial comparing the effects of 16 weeks of different aerobic exercise programs two days per week, and dietary intervention in a hypertensive, overweight/obese and non-physically active population. Aim To evaluate the influence of diet a...

Abbreviations: AC: Attention Control; BM: Body Mass; BP: Blood Pressure; CI: Confidence Interval; CRF: Cardiorespiratory Fitness; CPET: Cardiopulmonary Exercise Test; HTN: Primary Hypertension; HR: Heart Rate; HV-HIIT: High-Volume and High-Intensity Interval Training; ICC: Intraclass Correlation Coefficient; LV-HIIT: Low-Volume and High-Intensity...

The goal of the study was to compare the effects of two supervised aerobic exercise programs (moderate-intensity continuous training [MICT] vs. high-intensity interval training [HIIT]) after 8-, 12-, and 16-week intervention periods on cardiorespiratory fitness (CRF) in overweight/obese adults diagnosed with hypertension. Participants (N = 64) were...

Background. Exercise therapy has long been used for rehabilitation purposes after myocardial infarction (MI) and the benefit of regular physical exercise is also well established. High-intensity interval training (HIIT) has been proposed to be more effective than continuous exercise for improving exercise capacity, and health-related adaptations to...

Background Both exercise training and diet are recommended to prevent and control hypertension and overweight/obesity. Purpose The purpose of this study was to determine the effectiveness of different 16-week aerobic exercise programmes with hypocaloric diet on blood pressure, body composition, cardiorespiratory fitness and pharmacological treatme...

The main purpose of this study was to determine some key physical, physiological, clinical and nutritional markers of health status in obese and sedentary adults (54.0±8.1 years, 141 men and 68 women) with primary hypertension (HTN) characterized by sex and cardiorespiratory fitness (CRF) level. The studied population showed a high cardiovascular r...

Objective To evaluate the change in six-minute walk test (6-MWT) relative to changes in key functional capacity measures after 16-week of exercise training in older (>65 years) heart failure with preserved ejection fraction (HFpEF) patients. Design Prospective, randomized single blinded (by researchers to patient group) comparison of two groups of...

Objectives: Hypertension (HTN), obesity and low cardiorespiratory fitness (CRF) are associated with an increased risk of a cardiovascular event. Taking part overweight/obese individuals with HTN the aims of the current study were: to estimate cardiovascular risk (CVR) and vascular age (VA) profiles analyzing potential sex differences; to determine...

Background: The aims of the study were: to evaluate the relationship between Modified Shuttle Walk Test (MSWT) with peak oxygen uptake (V̇O2peak) in overweight/obese people with primary hypertension (HTN), and to develop an equation for the MSWT to predict VO2peak. Methods: Participants (N=256, 53.98.1 yr old) with HTN and overweight/obesity perfo...

In cycling, it is common practice to have a break in the off season longer than 4 weeks while adopting an almost sedentary lifestyle, and such a break is considered to be long-term detraining. No previous studies have assessed the effect of training cessation with highly trained young cyclists. The purpose of the present investigation was to examin...

Background: Both exercise training and diet are recommended to prevent and control primary hypertension (HTN) and overweight/obesity. Aerobic exercise is firmly established as an effective measure for lowering blood pressure (BP) and reducing cardiovascular risk. However, there is no agreement about the optimal dose of frequency, intensity, time an...

Background: Non-alcoholic fatty liver disease is the most frequent liver abnormality observed in overweight or obese children and is strongly associated with metabolic syndrome and insulin resistance. Objectives: (i) To evaluate the effect of a 22-week multidisciplinary intervention program on hepatic fat fraction in overweight or obese children...

Objective: Both exercise training (ET) and diet are recommended to prevent and treat hypertension. However, there is no agreement regarding the best treatment and its effect. Aims of the study were: 1) to compare the effects of two different aerobic exercise programs (moderate continuous exercise and high volume, MCT vs. high-intensity interval tra...

VIDEO DE LA CONFERENCIA / PRESENTATION VIDEO: http://ehutb.ehu.es/es/video/index/uuid/558bf48a3cb5f.html

Purpose: To examine the independent and combined influence of the FTOrs9939609 and the MC4Rrs17782313 polymorphisms on changes in fat mass (FM), resting energy expenditure (REE), leptin, and thyrotropin (TSH) levels, after a 12-week energy-restricted diet intervention in non-morbid premenopausal obese women. Methods: Fat mass (dual X-ray absorpt...

OBJETIVO. Comparar los efectos de dos programas de ejercicio físico (EF) aeróbico (continuo de intensidad moderada y alto volumen vs. interválico de alta intensidad y bajo volumen) en la masa y composición corporal, presión arterial (PA) y condición cardiorespiratoria en pacientes adultos con sobrepeso u obesidad e hipertensión primaria tratados co...

The optimal dose of physical activity (PA) in cancer survivors (CS) is unknown due to the large variety of types of cancer, illness stages and treatments, low cardiorespiratory fitness, and physical inactivity. It is recommended that CS follow current PA guidelines for healthy population. There are no specific exercise prescription guidelines for C...

Purpose: Beta-blockers (BB) are traditional pharmacotherapy for patients with heart failure with preserved ejection fraction (HFpEF). However, their impact on heart response of HFpEF patients during exercise and in recovery has not been studied. Moreover, heart rate (HR) values are widely used to determine and estimate exercise training intensities...

Cancer survivors (CS) can benefit with physical activity (PA). However, the optimal dose of PA in CS is unknown due to high variability of cancer types, illness phases and treatments, low cardiorespiratory fitness and physical inactivity. It is recommended to avoid inactivity and follow PA guidelines for healthy population. There are no specific ex...

Purpose. Physical exercise is recommended to prevent and control hypertension. However, there is no agreement about the optimal dose of frequency, intensity, duration and type of exercise. Aims of the study were 1) to compare high-intensity aerobic interval training (HIT) and moderate-intensity continuous exercise training (MCT) on blood pressure (...

Given that leptin, ghrelin and thyrotropin play a major role in the regulation of resting energy expenditure (REE) and that the FTO rs9939609 and the MC4R rs17782313 polymorphisms have been proposed to affect energy homeostasis, we hypothesized that both polymorphisms are associated with REE and that these relationships can be mediated by leptin, g...

Abstract The aim of this study was to analyse the association of morphology as well as functional outcomes during a paddling test with ranking position (RP) of competitive junior surfers. Ten male surfers (age, mean 17.60, s=2.06 years) performed a maximum incremental test on a modified ergometer (Ergo Vasa Swim, USA) to determine, per unit of weig...

The purpose of the present study was to investigate the influence of two exercise intensities (moderate and severe) on heart rate variability (HRV) response in 16 runners 1 hr prior to (-1 hr) and at +1 hr, +24 hr, +48 hr, and +72 hr following each exercise session. Time domain indexes and a high frequency component showed a significant decrease (p...

BACKGROUND. Hypertension is an important risk factor for cardiovascular diseases, affecting about 1 billion people worldwide, and is the top global risk factor for mortality. This risk is substantially reduced by a relatively small increase in exercise capacity, and the risk is declined progressively with increasing aerobic capacity. Physical exerc...

The purpose of the present study was to investigate the influence of two exercise intensities (moderate and severe) on heart rate variability (HRV) response in 16 runners 1 hr prior to (-1 hr) and at +1 hr, +24 hr, +48 hr, and +72 hr following each exercise session. Time domain indexes and a high frequency component showed a significant decrease (p...

Our objective was to investigate the influence of pedaling technique on gross efficiency (GE) at various exercise intensities in twelve elite cyclists ((V)over dotO(2)max = 75.7 +/- 6.2 ml.kg(-1).min(-1)). Each cyclist completed a (V)over dotO(2)max assessment, skinfold measurements, and an incremental test to determine their lactate threshold (LT)...

The warm-up procedure in traditional rowing usually involves continuous low-intensity rowing and short bouts of intense exercise, lasting about 60 min. To compare the effects of a traditional and an experimental 30-min warm-up of lower intensity on indoor rowing time-trial performance. Fourteen highly trained male rowers (age 25.9 ± 5.3 y, height 1...

The aims of the present study were to determine whether the estimations of the frontal area of the combined cyclist-bicycle (APCB) obtained with the Heil's non-logarithmic prediction equations (NPE) in the stem position (SP), brake hoods position (BHP) and drops position (DP) are comparable to the measured APCB with the computerized planimetry (CP)...

The warm-up procedure in traditional rowing usually involves continuous low-intensity rowing and short bouts of intense exercise, lasting about 60 min. PURPOSE: To compare the effects of a traditional and an experimental 30-min warm-up of lower intensity on indoor rowing time trial performance. METHODS: Fourteen highly-trained male rowers (age 25.9...