Sara HäkliUniversity of Eastern Finland | UEF · A.I. Virtanen Institute for Molecular Sciences
Sara Häkli
Master of Science
About
2
Publications
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Introduction
My research interest lies in neuropsychiatric and neurodegenerative diseases. Currently working with animal models of Alzheimer's disease and video-EEG recordings.
Publications
Publications (2)
BACKGROUND
Species-specific differences in astrocytes and their Alzheimer disease-associated pathology may influence cellular responses to other insults. Herein, human glial chimeric mice were generated to evaluate how Alzheimer disease predisposing genetic background in human astrocytes contributes to behavioral outcome and brain pathology after c...
Introduction:
There are no published data on prospective clinical studies on drug treatment options for sleep-related epileptiform spiking in Alzheimer's disease (AD).
Methods:
Using video-EEG with hippocampal electrodes in 17 APP/PS1 transgenic male mice we assessed the effects of donepezil and memantine, anti-seizure drugs levetiracetam and la...