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Argatroban is an anticoagulant which is used as direct thrombin inhibitor. It consists of hydrazine analogue, which is probably similar to Argatroban. The single HPLC method is already reported in to United States Pharmacopeia (USP). In that method, Argatroban peak eluted as R-Argatroban and S-Argatroban while hydrazine analogue eluted as P1 and P2...
Dexrabeprazole sodium (DEX•Na) is an active pharmaceutical ingredient and used as proton pump inhibitor. A reverse phase (RP) ultra-performance liquid chromatographic (UPLC) method is developed for determination of related impurities in DEX•Na and this method is validated using ICH guideline. This method was developed using BEH C18 (2.1 X 50 mm) 1....