Sanimah Simoh

Sanimah Simoh
Malaysian Agricultural Research and Development Institute, Serdang Selangor · Biotechnology Research Centre,

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18
Publications
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181
Citations

Publications

Publications (18)
Article
Lepisanthes fruticosa (ceri Terengganu) is one of the important underutilized fruit plants with high value of bioactive compounds and pharmacological properties. Current studies have focused mainly on the bioactive compounds which are essential for functional food and pharmaceutical applications. However, studies on the diversity and conservation o...
Experiment Findings
Full-text available
Penyakit hawar seludang adalah salah satu penyakit utama padi yang disebabkan oleh kulat patogenik tanah yang dikenali sebagai Rhizoctonia solani dan pencarian varieti padi yang rintang telah dijalankan secara meluas dalam program pembiakbakaan konvensional. Sebagai pendekatan alternatif, teknik kejuruteraan genetik telah diaplikasi untuk membangun...
Article
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Background: Dengue virus serotype 2 (DENV2) and West Nile virus (WNV) fevers are mosquito‑borne diseases with no effective treatment at present. In recent years, the development of plant‑based antivirals targeting the viral NS2B‑NS3 serine proteases has been the main focus as the synthetic antivirals available are not specific and less safe. Object...
Article
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Gynura procumbens and Cleome gynandra are two herbs commonly used in Malaysia to treat various ailments and are also consumed as salads (ulam) and vegetables. The present study aims to evaluate the relationship between the chemical compositions of both herbs and their antioxidant and anti-inflammatory properties using nuclear magnetic resonance (NM...
Article
Full-text available
The genomics and genetic data of pigmented and non-pigmented Malaysian rice varieties are still limited. Hence, we performed the genome resequencing of two black rice varieties (Bali, Pulut Hitam 9), two red rice varieties (MRM16, MRQ100) and two white rice varieties (MR297 and MRQ76) using Illumina HiSeq 4000 platform with 30x sequencing coverage....
Article
Full-text available
The proteome data of whole rice grain is considerably limited particularly for rice with pigmentations such as black and red rice. Hence, we performed proteome analysis of two black rice varieties (BALI and Pulut Hitam 9), two red rice varieties (MRM16 and MRQ100) and two white rice varieties (MR297 and MRQ76) using label-free liquid chromatography...
Article
Full-text available
Pigmented rice is enriched with antioxidants, macro- and micronutrients. A comprehensive investigation of the gene expression patterns among the pigmented rice varieties would help to understand the cellular mechanism and biological processes of rice grain pigmentation. Hence, we performed RNA sequencing and analysis on the whole grain of dehusked...
Article
Full-text available
This study aimed to determine the total phenolic content, DPPH scavenging, α-glucosidase, and nitric oxide (NO) inhibition of Gynura procumbens and Cleome gynandra extracts obtained with five different ethanolic concentrations. The findings showed that the 100% ethanolic extract of G. procumbens had the highest phenolic content and the lowest IC50...
Article
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Recently, rice breeding program has shown increased interests on the pigmented rice varieties due to their benefits to human health. However, the genetic variation of pigmented rice varieties is still scarce and remains unexplored. Hence, we performed genome-wide SNP analysis from the genome resequencing of four Malaysian pigmented rice varieties,...
Article
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Curcuma aeruginosa or temu hitam is herbaceous plant with high therapeutic values in its rhizome that is widely used in traditional medicine. However, molecular studies on the secondary metabolite biosynthetic pathway of C. aeruginosa is still limited. Hence, the aim of this study was to explore and reconstruct the secondary metabolite biosynthetic...
Article
Full-text available
A comparative analysis of metabolites from different parts of Curcuma aeruginosa, i.e. leaves, stems, adventitious roots and rhizomes was performed by GC-MS/MS coupled with multivariate statistical analysis. The GC-MS/MS analysis confirmed the occurrence of 26 metabolites belonged to terpenoids in almost all the samples. The Principal Component Ana...
Article
Full-text available
Objective: To investigate the possible phytochemical constituents of Curcuma aeruginosa Roxb. (C. aeruginosa) rhizome using two different techniques of direct solvent extraction. Methods: Two different techniques of direct solvent extractions, i.e. methyl tert-butyl ether (MTBE) extraction and two-phase methanol/chloroform (M/C) system, were used i...
Article
Full-text available
Cosmos caudatus, which is a commonly consumed vegetable in Malaysia, is locally known as “Ulam Raja”. It is a local Malaysian herb traditionally used as a food and medicinal herb to treat several maladies. Its bioactive or nutritional constituents consist of a wide range of metabolites, including glucosinolates, phenolic, amino acids, organic acids...
Article
Unlabelled: Cosmos caudatus, which is known as "Ulam Raja," is an herbal plant used in Malaysia to enhance vitality. This study focused on the evaluation of the α-glucosidase inhibitory activity of different ethanolic extracts of C. caudatus. Six series of samples extracted with water, 20%, 40%, 60%, 80%, and 100% ethanol (EtOH) were employed. Gas...
Article
Full-text available
Seven developmental stages of Michelia alba (cempaka putih) flowers namely Stage 5 to 11 (S5-S11) were investigated for their volatile compounds. The essential oil was isolated by Simultaneous Distillation Extraction (SDE) technique and the oil obtained was subjected to Gas Chromatography-Mass Spectrometry (GC-MS) analysis. In total, 78 compounds r...

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