Sang-Won Lee

Korea University | KU · Department of Chemistry

Combining recycling and additive manufacturing (AM) can bring significant environmental and economic advantages. Using recycled materials can help reduce waste and the need for virgin materials, which can be resource-intensive to extract and process. Recycling is also more energy-efficient than extracting and processing virgin materials. This paper...

Objective: Acceptance and commitment therapy (ACT) has been recently introduced for treating obsessive-compulsive disorder (OCD). Although there are data supporting the efficacy of ACT, only few studies have investigated the effectiveness of ACT against any obsessivecompulsive (OC) symptom dimension or a specific dimension alone. Methods: In tot...

Directed energy deposition (DED) stands as a key process in metal additive manufacturing (AM) and offers the unique capability of creating functionally graded materials (FGMs). FGMs have garnered significant interest in high-value industries by advantages such as performance optimization, reducing material defects, and resolving joining issues. How...

Background: Loss of companion animals can result in various psychological reactions, including complicated grief, depression, anxiety, and insomnia. However, research on the prevalence of patients requiring clinical intervention is limited. Moreover, research examining the relationship between childhood trauma and psychological symptoms after pet...

Background: There is growing evidence for the use of acceptance-commitment therapy (ACT) for the treatment of obsessive-compulsive disorder (OCD). However, few fully implemented ACT have been conducted on the neural mechanisms underlying its effect on OCD. Thus, this study aimed to elucidate the neural correlates of ACT in patients with OCD using...

Conformal deposition of perovskite films on textured silicon surfaces using a dry process is crucial for producing high‐performance perovskite/silicon tandem solar cells. Herein, a radio frequency magnetron sputtering process is used with a PbI 2 target to deposit precursor films. Iodination, thermal annealing, and dimethyl sulfoxide treatment are...

The miniaturisation of electronic devices demands advanced microelectronics packaging systems dominated by interconnection reliability. Thermo-compression bonding (TCB) is a promising approach to improve bonding quality by applying heat and pressure onto the chip. However, TCB has prompted severe mechanical warpage and electrical shortage when the...

Objective: Thought-action fusion (TAF), which is a tendency to make the relationship between one's thoughts and external consequences, is a dysfunctional belief linked to obsessive-compulsive disorder (OCD). While the TAF is commonly evaluated using the Thought-Action Fusion Scale (TAFS), it cannot fully reflect the actual experience of experiment...

To support efficient, balanced news consumption, merging articles from diverse sources into one, potentially through crowdsourcing, could alleviate some hurdles. However, the merging process could also impact annotators' attitudes towards the content. To test this theory, we propose comparative news annotation, i.e., annotating similarities and dif...

Childhood maltreatment (CM) causes early deviations in cognitive and affective processes, leading to future adaptation failures and psychopathology. Specifically, CM has been linked to cognitive distortions, and recent studies have focused on the impact of CM on the higher level of metacognitive beliefs. However, only a few studies have revealed th...

The objective of this study is to develop a surface quality prediction model for CFRP milling based on artificial intelligence and enhance the model performance by proposing a novel feature through signal processing and applying it to machine learning algorithms. In this paper, the data-driven approach is applied based on data that is obtained by v...

The directed energy deposition (DED) process is attracting significant attention in high value-added industries, such as automobiles and aviation, because the process can freely manufacture components with complex shapes and directly stack them on metal substrates. However, it has a problem of degradation in reliability and poor reproducibility due...

In recent years, acceptance and commitment therapy (ACT) has become one of the most promising developments in the treatment of obsessive-compulsive disorder (OCD). Although cumulative evidence supporting the efficacy of individual ACT as a therapeutic intervention for OCD has been reported, research on the efficacy of group ACT (GACT) remains insuf...

Participating in physical exercise using remote platforms is challenging for people with vision impairment due to their lack of vision. Thus, there is a need to provide nonvisual feedback to this population to improve the performance and safety of remote exercise. In this study, the effects of different nonvisual types of feedback (verbal, vibrotac...

Interleukin-7 (IL-7) is an essential cytokine for T-cell homeostatic proliferation and maintenance. Clinical studies have shown the potential benefits of IL-7 therapy in various diseases associated with lymphopenia. However, the kinetics of the T-cell response to a single administration of IL-7 in humans have not been fully elucidated. Here, we inv...

A processing map is required for Ti alloys to find processing parameters securing a high formability. This study adopted the extreme gradient boosting (XGB) approach of machine learning to predict a flow curve and plot a processing map with less experiments for the first time. The optimum XGB model predicted flow curves of Ti-6Al-2Sn-2Zr-2Mo-2Cr0.1...

Due to inherent drawbacks of metal 3D printing process such poor dimensional accuracy, surface quality, and various defects, a process monitoring system with an appropriate information visualization interface has been required. In the recent technological mega-trend, the 4th industrial revolution, the digital twin technology has received much atten...

Modern knowledge workers typically need to use multiple resources, such as documents, web pages, and applications, at the same time. This complexity in their computing environments forces workers to restore various resources in the course of their work. However, conventional curation methods like bookmarks, recent document histories, and file syste...

Mitochondria in neural progenitors play a crucial role in adult hippocampal neurogenesis by being involved in fate decisions for differentiation. However, the molecular mechanisms by which mitochondria are related to the genetic regulation of neuronal differentiation in neural progenitors are poorly understood. Here, we show that mitochondrial dysf...

A carbon fiber reinforced plastic (CFRP) composite has been utilized for high-tech industries owing to their superior mechanical properties such as a high strength-to-weight ratio. However, a CFRP composite has anisotropy and non-homogeneity, and these properties can cause defects during machining processes. The objective of this study is to compre...

Objective: Recent studies highlighted the triple-network model which illustrated the interactions among three large-scale networks including salience network (SN). The functional magnetic resonance imaging used in this study was designed to investigate the characteristics of three large-scale networks associated with the thought-action fusion (TAF...

An ideal vaccine for controlling Salmonella infection in chicken flocks should be safe, inducing both humoral and cellular immunity. Live attenuated vaccines against Salmonella Enteritidis (S. Enteritidis) have been used as a potential control method of Salmonella infection in the poultry industry. However, live attenuated vaccines can persistently...

Protein phosphorylation is a prevalent post-translational modification that regulates essentially every aspect of cellular processes. Currently, liquid chromatography-tandem mass spectrometry (LC-MS/MS) with an extensive offline sample fractionation and a phosphopeptide enrichment method is a best practice for deep phosphoproteome profiling, but ba...

High-grade serous ovarian cancer (HGSOC) represents the major histological type of ovarian cancer, and the lack of effective screening tools and early detection methods significantly contributes to the poor prognosis of HGSOC. Currently, there are no reliable diagnostic biomarkers for HGSOC. In this study, we performed liquid chromatography data-in...

Aim: Sphingosine-1-phosphate receptor mediates the egress of lymphocytes from lymphoid organs, and its inhibition results in a decreased number of circulating lymphocytes. The aim of the current study was to investigate the safety and pharmacodynamic and pharmacokinetic characteristics of a novel sphingosine-1-phosphate receptor modulator, LC51-025...

We investigated the cross-species transmission of rabbit hepatitis E virus (rb HEV) to pigs and evaluated the cross-protection of a swine (sw) HEV-3 virus-like particle (VLP) vaccine against rb HEV infection in pigs. Twelve 4-week-old conventional pigs were divided into negative control (n = 3), positive control (rb HEV-infected, n = 4), and vaccin...

Here, rabbits were immunized with a virus-like particle (VLP) vaccine prepared by expressing 239 amino acids of the swine hepatitis E virus (HEV)-3 capsid protein using a baculovirus system. Thirty specific-pathogen-free rabbits were divided into five groups (negative and positive control and 10, 50, and 100 μg VLP-vaccinated). Positive control gro...

Canine coronavirus (CCoV), canine parvovirus (CPV), and canine distemper virus (CDV) are highly contagious canine pathogens; dogs with these diseases are difficult to treat. In a previous study, we developed a recombinant adenovirus expressing canine interferon lambda 3 (Ad-caIFNλ3) in canine epithelial cells. This study aimed at investigating the...

e17564 Background: Ovarian cancer (OC) is one of the most common causes of cancer-related death among women worldwide. High-grade serous ovarian cancer (HGSOC) represents the major OC histological type, and challenges associated with its early detection and prediction of clinical outcomes significantly contribute to the high prevalence and poor pro...

Hepatitis E virus (HEV) is an emerging zoonotic pathogen causing hepatitis worldwide. Despite the prevalent evidence of interspecies HEV infection in various animal species, the role of horses in HEV epidemiology remains unclear. In this study, we investigated the prevalence of HEV infection in 283 blood and 114 fecal samples from 397 horses using...

The Torque teno canis virus (TTCaV) is a 2.8 kb-long circular single-stranded DNA virus that has been reported to cause infections in dogs. In this study, 135 fecal samples of dogs were collected in South Korea to determine TTCaV infection status. When the prevalence was determined by polymerase chain reaction (PCR), 17 of 135 (12.6%) patients test...

Vaccination is a practical method to provide protection against porcine reproductive and respiratory syndrome virus (PRRSV), but current PRRSV vaccines show limited efficacy against divergent field strains. Lineage 1 PRRSV includes virulent strains such as NADC30 and MN184 and now has become one of the most prevalent viruses in Korea. Accordingly,...

Chemical pesticides are still frequently overused to diminish such crop loss caused by biotic stress despite the threat to humans and the environment. Thus, it is urgent to find safer and more effective defense strategies. In this study, we report that caffeine, implanted through a transgenic approach, enhances resistance against variable biotic st...

To promote engagement, recommendation algorithms on platforms like YouTube increasingly personalize users' feeds, limiting users' exposure to diverse content and depriving them of opportunities to reflect on their interests compared to others'. In this work, we investigate how exchanging recommendations with strangers can help users discover new co...

In this work, nickel silicide was applied to tandem solar cells as an interlayer. By the process of thermal evaporation, a layer of NiOx, hole transport layer (HTL) was deposited on n+ poly-Si layer directly. Nickel silicide was simultaneously formed by nickel diffusion from NiOx to n+ poly-Si layer during the deposition and annealing process. The...

Reducing the peripheral absolute lymphocyte count (ALC) is a promising therapeutic approach in treating autoimmune diseases. LC51-0255 is a sphingosine-1phosphate 1 receptor modulator, which is known to decrease the peripheral ALC. We aimed to assess the pharmacokinetics (PK), pharmacodynamics (PD), safety, and tolerability profiles of LC51-0255 af...

We present a novel dual-band SRS pulsed fiber laser, which alternates the excitation wavelengths between 545 and 599 nm using stimulated Raman scattering (SRS) effect for high-speed photoacoustic (PA) sensing and imaging.

Objective: Pathological features indicating metastatic mucinous carcinoma to the ovary (MMCO) have been rarely reported in primary mucinous ovarian carcinoma (PMOC). However, little is known about how often they are observed in PMOC and how they relate to patient prognosis. In this study, we investigated the pathological features indicating MMCO i...

Objective: Thought-action fusion (TAF), one of the most-studied dysfunctional beliefs in obsessive-compulsive disorder, represents an individual's belief that his/her thoughts directly influence events. TAF belief types are divided into personal thoughts relating to positive (positive TAF) and negative outcomes (negative TAF). However, the neural...

Short tandem repeats (STRs) are the most popular markers for human identification in forensics. These markers can be easily analyzed through a multiplex polymerase chain reaction and electrophoresis and provide high discrimination power. However, in STR analysis, several atypical phenomena can be observed such as allelic dropouts, drop-ins, or imba...

Struggling to curb misinformation, social media platforms are experimenting with design interventions to enhance consumption of credible news on their platforms. Some of these interventions, such as the use of warning messages, are examples of nudges---a choice-preserving technique to steer behavior. Despite their application, we do not know whethe...

As news organizations embrace transparency practices on their websites to distinguish themselves from those spreading misinformation, HCI designers have the opportunity to help them effectively utilize the ideals of transparency to build trust. How can we utilize transparency to promote trust in news? We examine this question through a qualitative...

Purpose The balloon-stent technique (BST) has certain strengths as an assisted technique for the treatment of complex aneurysms. After Atlas release, the BST can be executed without an exchange maneuver of the balloon to the stent-delivery catheter. The purpose of this article is to share our experience with the BST using the Scepter-Atlas combinat...

Construction sites experience low productivity due to particular characteristics such as unique designs in each project, sporadic arrival of projects, and complexity of the process. Another contributing factor to low productivity is poor communication among workers, supervisors, and a site’s centralized knowledge hub. Research shows that introducin...

Background/aims: After esophagogastroduodenoscopy (EGD) with biopsy, some patients experience gastrointestinal symptoms. This study investigated the effect of sodium alginate on biopsy-related gastrointestinal symptoms. Methods: In this open-label, randomized, controlled trial, patients undergoing EGD with biopsy were randomly assigned to a trea...

Tandem solar cells which are electrically connected with various photoactive materials have the potential to solve the current challenges by exceeding the theoretically limited efficiency of single junction solar cells. Here we report the first monolithic organic/silicon tandem cell based on a semi-transparent polymer on a crystalline silicon (c-Si...

As news organizations embrace transparency practices on their websites to distinguish themselves from those spreading misinformation, HCI designers have the opportunity to help them effectively utilize the ideals of transparency to build trust. How can we utilize transparency to promote trust in news? We examine this question through a qualitative...

Struggling to curb misinformation, social media platforms are experimenting with design interventions to enhance consumption of credible news on their platforms. Some of these interventions, such as the use of warning messages, are examples of nudges -- a choice-preserving technique to steer behavior. Despite their application, we do not know wheth...

An iatrogenic diaphragmatic hernia after major hepatic resection is a rare complication. Incarceration of the abdominal organ through a diaphragmatic defect can have a fatal prognosis. Here, we report a case of incarcerated diaphragmatic hernia after right hepatectomy, which was diagnosed only after the autopsy. The deceased, who had right hepatect...

In many collaborative tasks, the need for joint attention arises when one of the users wants to guide others to a specific location or target in space. If the collaborators are co-located and the target position is in close range, it is almost instinctual for users to refer to the target location by pointing with their bare hands. While such pointi...

Objective: Although cognitive models of obsessive-compulsive disorder (OCD) fall into two categories: cognitive deficit models and dysfunctional belief models, these approaches have their own ways and have hardly been reconciled. Therefore, this study aimed to investigate the potential relationships between cognitive deficit (using the Wisconsin C...

Maltreatment experiences alter brain development associated with emotion processing, and dysregulation of emotion may trigger mental health problems in maltreated people. However, studies revealing alterations in brain networks during cognitive reappraisal in victims of maltreatment are strikingly insufficient. In this study, 27 healthy subjects we...