Sang-Won Lee

• Korea University

Recombinant human interleukin‐7 hybrid Fc (rhIL‐7‐hyFc) is a homodimer of rhIL‐7 fused to a hyFc. Exogenous IL‐7 promotes T cell proliferation and increases lymphocyte count, making it a potential treatment option for lymphopenia and cancer. To improve therapeutic efficacy, rhIL‐7‐hyFc was developed as a long‐acting IL‐7. This study aimed to create...

Objective Resilience is the ability to bounce back from stressful events using individual and environmental resources. The online intervention program, MoVemEnT, which includes mindfulness training and emotion regulation, was developed to enhance resilience among young adults.Methods Persons without current medical or psychiatric diseases, aged 20–...

CO2‐assisted oxidative dehydrogenation of ethane is a sustainable alternative to steam cracking for ethylene production. In this study, a series of CeO2 on SiO2 supported NiFe3 catalysts were synthesized by incipient wetness impregnation and tested for oxidative dehydrogenation performance. The CeO2/SiO2 supported catalysts with high weight loading...

The prevalence of distressing content on social media raises concerns about users' mental well-being, prompting the use of trigger warnings (TW) and content warnings (CW). However, inconsistent implementation of TW/CW across platforms and the lack of standardized practices confuse users regarding these warnings. To better understand how users exper...

Automating fabric manipulation in garment manufacturing remains a challenging task due to the characteristics of limp sheet materials and the diversity of fabrics used. This paper introduces an adaptive and optimized robotic fabric handling system, designed to address these challenges. The system comprises an industrial robot, four needle grippers,...

Live-streamed group exercise programmes are used increasingly to start or maintain physical activity behaviours. However, participants’ performance and long-term engagement can be impacted in live-streamed programmes due to communication gaps with the instructors and peers. We analysed verbal and nonverbal communication differences between in-perso...

As modern manufacturing systems increasingly employ adaptive control mechanisms, there is a need for monitoring solutions that can operate robustly across varying process conditions. In particular, the thin wire flattening process requires a control-resilient model to predict roller wear—a critical factor affecting wire quality even—as roller rotat...

Background Childhood maltreatment could have a negative impact on emotional1 and cognitive2 development, and it can be vulnerable factors for mental illness. Aim & Objectives This study aimed to demonstrate the effects of maltreatment on cognitive function in young adults by using various cognitive measurements, including computerized test. Metho...

Objective Evidence suggests that acceptance and commitment therapy (ACT) processes function as transdiagnostic factors in both major depressive disorder (MDD) and obsessive-compulsive disorder (OCD) individually. However, few studies have directly compared these two clinical disorders. Therefore, this study aimed to identify potential transdiagnost...

Significance Developments of anti-gametocyte drugs have been delayed due to insufficient understanding of gametocyte biology. We report a systematic workflow of data processing algorithms to quantify changes in the absorption spectrum and cell morphology of single malaria-infected erythrocytes. These changes may serve as biomarkers instrumental for...

As large language models (LLMs) advance and become widespread, students increasingly turn to systems like ChatGPT for assistance with writing tasks. Educators are concerned with students' usage of ChatGPT beyond cheating; using ChatGPT may reduce their critical engagement with writing, hindering students' learning processes. The negative or positiv...

Polyethylene terephthalate (PET) bottles are widely used for food and beverage packaging, produced through blow-molding processes. Defects in PET bottles often arise due to improper process conditions, with visual inspections commonly performed by workers. However, the growing importance of quality assurance in consumer goods has driven demand for...

Electrified interfaces are critical to the performance of energy systems and often demonstrate substantial complexity under operating conditions. Nanoscale understanding of the interfacial microenvironment, i.e., the solid electrolyte interphase (SEI), in lithium-mediated nitrogen reduction (Li-N2R) is key for realizing efficient ammonia (NH3) prod...

Online inductively coupled plasma mass spectrometry (ICP-MS) is a powerful tool for investigating degradation behavior of electrochemical systems in situ . By coupling a potentiostat to an ICP-MS, one can simultaneously probe material degradation and reaction kinetics of electrochemical systems. High instrument sensitivity allows for quantifying tr...

The integration of renewable energy with industrially relevant CO 2 electrolyzers provides a promising pathway to achieving sustainable fuels and chemical generation. In this work, mass transport phenomena in a zero-gap membrane-electrode-assembly (MEA) are investigated by varying the thickness of the gaskets used during cell assembly, which in tur...

Despite global initiatives to address climate change, the year 2023 was the hottest year ever recorded in history. The need for technologies to lower carbon emissions and to remove already emitted greenhouse gases is immense. There have been massive efforts to electrochemically drive CO 2 conversion to value-added chemicals such as ethylene, ethano...

Despite the existence of search-based recommender systems like Google, Netflix, and Spotify, online users sometimes may turn to crowdsourced recommendations in places like the r/ifyoulikeblank subreddit. In this exploratory study, we probe why users go to r/ifyoulikeblank, how they look for recommendation, and how the subreddit users respond to rec...

Radio frequency (RF) magnetron sputtering is a vapor deposition technique known for its good step coverage, high material utilization, and industrial adaptability. However, its application in the deposition of lead iodide (PbI2), a key semiconductor in photovoltaic applications, has been underexplored. In this study, for the first time, the corr...

Online hate speech has become increasingly prevalent on social media platforms, causing harm to individuals and society. While efforts have been made to combat this issue through content moderation, the potential of user-driven counterspeech as an alternative solution remains underexplored. Existing counterspeech methods often face challenges such...

Handheld devices have become an inclusive alternative to head-mounted displays in virtual reality (VR) environments, enhancing accessibility and allowing cross-device collaboration. Object manipulation techniques in 3D space with handheld devices, such as those in handheld augmented reality (AR), have been typically evaluated in table-top scale and...

Brain entropy (BEN), which measures the amount of information in brain activity, provides a novel perspective for evaluating brain function. Recent studies using resting-state functional magnetic resonance imaging (fMRI) have shown that BEN during rest can help characterize brain function alterations in schizophrenia (SCZ). However, there is a lack...

The electrochemical CO 2 reduction reaction (CO 2 RR) provides a path towards sustainable production of carbon-based fuels and chemicals, using renewable electricity to drive the conversion of CO 2 into products such as ethylene, ethanol, and methane. A challenge limiting the implementation of CO 2 RR is catalyst stability during operation, and gre...

Lithium-mediated nitrogen reduction (Li-N2R) can be distributed and powered by renewable energy, making it a sustainable ammonia production alternative to the Haber Bosch process. While Haber Bosch is responsible for 1.3% of CO2 emissions yearly and requires centralized facilities with high temperatures and pressures, Li-N2R works at near-ambient c...

Integrated solar fuels devices for CO 2 reduction (CO 2 R) are a promising technology class towards achieving net-negative carbon emissions. Designing integrated CO 2 R solar fuels devices requires careful co-design of electrochemical and photovoltaic components as well as consideration of the diurnal and seasonal effects of solar irradiance, tempe...

Objectives Childhood maltreatment can negatively impact cognitive development, including executive function, working memory, and processing speed. This study investigated the impact of childhood maltreatment on cognitive function in young adults using various measurements, including computerized tests, and their relationship with emotional dysregul...

The advancement of prognostics and health management (PHM) using the industrial internet of things (IIoT) and artificial intelligence (AI) has enabled stable mass production with assured quality. However, the manufacturing industry often faces variable conditions like design and material changes. Before applying PHM systems, it is crucial to design...

Joint reading is a key activity for early learners, with caregiver-child interactions such as questioning and feedback playing an essential role in children's cognitive and linguistic development. However, for some parents, actively engaging children in storytelling can be challenging. To address this, we introduce TaleMate a platform designed to e...

Electrified interfaces are critical to the performance of energy systems and often demonstrate substantial complexity under operating conditions. Nanoscale understanding of the interfacial microenvironment, i.e., the solid electrolyte interphase (SEI), in lithium-mediated nitrogen reduction (Li-N2R) is key for realizing efficient ammonia production...

GIFs afford a high degree of personalization, as they are often created from popular movie and video clips with diverse and realistic characters, each expressing a nuanced emotional state through a combination of characters' own unique bodily gestures and distinctive visual backgrounds. These properties of high personalization and embodiment provid...

Research has identified applications of handheld-based VR, which utilizes handheld displays or mobile devices, for developing systems that involve users in mixed reality (MR) without the need for head-worn displays (HWDs). Such systems can potentially accommodate large groups of users participating in MR. However, we lack an understanding of how gr...

Photoelectrochemical production of ammonia (NH3) is potentially eco-friendly but suffers from a low solar-to-ammonia productivity (SAP) and requires a high additional bias for the overall NH3 production from nitrate reduction and water oxidation. Here we applied a high-performance triple-cation lead halide (Cs0.05(FA0.83MA0.17)0.95Pb(Br0.17I0.83)3)...

Objective The Acceptance and Action Questionnaire for Obsessions and Compulsions (AAQ-OC) is a version of the Acceptance and Action Questionnaire (AAQ) that specifically measures unwanted intrusive thoughts and responses (e.g., experiential avoidance) to them. This study aimed to investigate the reliability and validity of the Korean version of the...

Digital holography requires precise phase analysis without wavefront aberration from defocusing errors. While the auto-contrast method is generally advantageous for refocusing, its accuracy suffers in low contrast conditions. Here, we suggest a simple phase analysis approach applying phase-detection autofocusing (PDAF) using a Fourier operation and...

Background: This study aimed to retrospectively assess results of intracranial meningioma surgery with or without intraoperative neuromonitoring (IONM) in a single institution. Methods: Two cohorts (a historical cohort and a monitoring cohort) were collected for the analysis. Before IONM was introduced, a total of 107 patients underwent intracra...

ViSiON (visualization materials composed of silicon‐based optical nanodisks) is presented, which offers a unique optical combination of near‐infrared (NIR) optical properties and biodegradability. Initially, numerical simulations are conducted to calculate the total extinction and scattering effects of ViSiON by the diameter‐to‐thickness ratio, pre...

Over the past few decades, the increased application of nanomaterials has raised questions regarding their safety and possible toxic effects. Organoids have been suggested as promising tools, offering efficient assays for nanomaterial-induced toxicity evaluation. However, organoid systems have some limitations, such as size heterogeneity and poor p...

Childhood maltreatment (CM) causes early deviations in cognitive and affective processes, leading to future adaptation failures and psychopathology. Specifically, CM has been linked to cognitive distortions, and recent studies have focused on the impact of CM on the higher level of metacognitive beliefs. However, only a few studies have revealed th...

Directed energy deposition (DED) process is a representative metal additive manufacturing technology that uses a flexible deposition head mainly used for repairs in space and marine industries. The DED process saves time and money as it repairs only damaged parts and components. Therefore, a geometric control is important to fill the volume of the...

Integrated solar fuels devices for CO 2 reduction (CO 2 R) are a promising technology class towards reducing CO 2 emissions.

The industrial synthesis of ammonia (NH 3 ) via the Haber-Bosch process has enabled mass production of fertilizer and the human population growth to 8 billion. ¹ NH 3 also shows promise as a long-term, energy-dense fuel amenable to widespread distribution. ² However, the Haber-Bosch process operates at high temperatures and pressures in centralized...

This study investigated the integration of perovskite solar cells (PSCs) on stainless steel (SS) substrates for application in building-integrated photovoltaics (BIPV). Using advanced atomic force microscopy measurements, we confirmed that enhanced substrate roughness increased the reflectance along an interface. Consequently, a remarkable final ef...

A key component of vehicle production automation is an industrial robot, and the robotic spot-welding (RSW) process is crucial due to more than 5000 spot-welds per vehicle. Due to the large number of welds, the quality of each weld must be adequately monitored and controlled; therefore, an automatic diagnostic system is required. In this paper, a r...

Combining recycling and additive manufacturing (AM) can bring significant environmental and economic advantages. Using recycled materials can help reduce waste and the need for virgin materials, which can be resource-intensive to extract and process. Recycling is also more energy-efficient than extracting and processing virgin materials. This paper...

Objective: Acceptance and commitment therapy (ACT) has been recently introduced for treating obsessive-compulsive disorder (OCD). Although there are data supporting the efficacy of ACT, only few studies have investigated the effectiveness of ACT against any obsessivecompulsive (OC) symptom dimension or a specific dimension alone. Methods: In tot...

Directed energy deposition (DED) stands as a key process in metal additive manufacturing (AM) and offers the unique capability of creating functionally graded materials (FGMs). FGMs have garnered significant interest in high-value industries by advantages such as performance optimization, reducing material defects, and resolving joining issues. How...

Background: Loss of companion animals can result in various psychological reactions, including complicated grief, depression, anxiety, and insomnia. However, research on the prevalence of patients requiring clinical intervention is limited. Moreover, research examining the relationship between childhood trauma and psychological symptoms after pet...

Background: There is growing evidence for the use of acceptance-commitment therapy (ACT) for the treatment of obsessive-compulsive disorder (OCD). However, few fully implemented ACT have been conducted on the neural mechanisms underlying its effect on OCD. Thus, this study aimed to elucidate the neural correlates of ACT in patients with OCD using...

Conformal deposition of perovskite films on textured silicon surfaces using a dry process is crucial for producing high‐performance perovskite/silicon tandem solar cells. Herein, a radio frequency magnetron sputtering process is used with a PbI2 target to deposit precursor films. Iodination, thermal annealing, and dimethyl sulfoxide treatment are e...

The miniaturisation of electronic devices demands advanced microelectronics packaging systems dominated by interconnection reliability. Thermo-compression bonding (TCB) is a promising approach to improve bonding quality by applying heat and pressure onto the chip. However, TCB has prompted severe mechanical warpage and electrical shortage when the...

Objective: Thought-action fusion (TAF), which is a tendency to make the relationship between one's thoughts and external consequences, is a dysfunctional belief linked to obsessive-compulsive disorder (OCD). While the TAF is commonly evaluated using the Thought-Action Fusion Scale (TAFS), it cannot fully reflect the actual experience of experiment...

To support efficient, balanced news consumption, merging articles from diverse sources into one, potentially through crowdsourcing, could alleviate some hurdles. However, the merging process could also impact annotators' attitudes towards the content. To test this theory, we propose comparative news annotation, i.e., annotating similarities and dif...

Childhood maltreatment (CM) causes early deviations in cognitive and affective processes, leading to future adaptation failures and psychopathology. Specifically, CM has been linked to cognitive distortions, and recent studies have focused on the impact of CM on the higher level of metacognitive beliefs. However, only a few studies have revealed th...

The objective of this study is to develop a surface quality prediction model for CFRP milling based on artificial intelligence and enhance the model performance by proposing a novel feature through signal processing and applying it to machine learning algorithms. In this paper, the data-driven approach is applied based on data that is obtained by v...

The directed energy deposition (DED) process is attracting significant attention in high value-added industries, such as automobiles and aviation, because the process can freely manufacture components with complex shapes and directly stack them on metal substrates. However, it has a problem of degradation in reliability and poor reproducibility due...