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Publications (213)
Gurguéia nut represents a rich source of lipids and bioactive compounds with the potential for sustainable exploitation. In this work, the nutritional composition, and functional properties of gurguéia cakes obtained by hydraulic press (C1), supercritical CO2 (C2), and Soxhlet (SOX) with hexane (C3) were evaluated. In addition, hydroethanolic extra...
Chlorella vulgaris is a potential sustainable source of lipids, carotenoids, carbohydrates, and proteins, as it shows high biomass productivity and easy cultivation. Therefore, the aim of this work was to critically discuss the cultivation and characterization of C. vulgaris, and also the aspects related to the application of green extraction techn...
Dipteryx lacunifera, known as gurguéia nut, is a potential crop for obtaining specialty oils. The processing of gurguéia nut to obtain the oil generates circa 635 g kg⁻¹ of cake, a biomass rich in residual oil. A sequential approach using hydraulic pressing (HP) and supercritical fluid extraction with CO2 (SFE-CO2) has been employed to maximize the...
Biodegradable polyesters, such as the poly(lactic-co-glycolic acid) (PLGA), have been extensively used as a polymer matrix for entrapping a variety of active compounds. In this study, the physicochemical phenomena that control the mass transport mechanism of hydrophilic compounds released from PLGA microspheres were identified. This study aims to p...
In global exports, the commodity banana generates billions of dollars annually, a market which is accompanied by the discard of extraordinary amounts of valuable agricultural material from banana trees, mainly pseudostems, leaves, and hearts (banana inflorescence). The recovery of high-added value natural compounds from agri-food by-products is an...
There is an increasing demand for functional foods to attend the consumers preference for products with health benefits. Peach (Prunus persica), from Rosaceae family, is a worldwide well-known fruit, and its processing generates large amounts of by-products, consisting of peel, stone (seed shell + seed), and pomace, which represent about 10% of the...
Due to its high nutritional content, delectable flavor, and advantageous health effects, cashew production has recently expanded significantly on a global scale. Massive quantities of cashew by-products (nut shell, testa shell, nut meal, and bagasse) are produced during cashew industrial processing, with adverse environmental and economic effects....
Kappaphycus alvarezii (KA) is a widespread worldwide alga, and one of the main industrial sources of carrageenan. Besides, KA biomass also contains other substances such as phenolic compounds and fatty acids that can be recovered by several methods. Then, this work aimed to investigate the eco-friendly methods, for the recovery of fatty acids, phen...
The fruits from the Arecaceae family, although being rich in bioactive compounds with potential benefits to health, have been underexplored. Studies on their composition, bioactive compounds, and effects of their consumption on health are also scarce. This review presents the composition of macro- and micronutrients, and bioactive compounds of frui...
Peanut skin is a by-product rich in bioactive compounds with high nutritional and pharmaceutical values. The phenolic fraction, rich in proanthocyanidins/procyanidins, is a relevant class of bioactive compounds, which has been increasingly applied as functional ingredients for food and pharmaceutical applications and is mostly recovered from peanut...
Deep eutectic solvents (DES) were selected as water modifiers to perform the subcritical water extraction (SWE), aiming at the selective extraction of anthocyanins from black beans hulls. To identify an efficient and environmentally friendly solvent, the COSMO-RS model was used, which was able to predict the affinities of individual anthocyanins in...
This study aims to recover pectin from the jaboticaba by-product using subcritical water extraction modified by deep eutectic solvent (SWE-DES). The extractions followed a Box-Behnken Factorial Design and the operational conditions were optimized through response surface methodology (RSM), being 122 °C, 8% DES, and a flow rate of 2 mL/min. The pect...
Mushrooms are known for their medicinal value and health benefits, particularly the species Agaricus bisporus, which is rich in bioactive components. However, there are difficulties in determining bioactive compounds, as different extraction methods are rarely investigated and may yield extracts with different chemical profiles. For food and pharma...
Gas antisolvent (GAS), based on antisolvent feature of supercritical CO2, was unlikely explored to obtain cocrystals of quercetin/nicotinamide (QUE/NIC). Cocrystallization is an emerging technique to improve physicochemical properties of active compounds such as quercetin. QUE/NIC cocrystals were prepared by GAS with acetone as solvent, and the res...
Peanut (Arachis hypogea L.) industrial processing generates underused by-products, which are mostly discharged. In this work, extracts from peanut by-product were obtained by Supercritical Fluid Extraction (SFE), Pressurized Liquid Extraction (PLE) and Subcritical Water Extraction (SWE), and compared to Soxhlet (SOX). Yield values varied from 12.94...
This review provides information on nutritional characteristics, extraction techniques, bioactive compounds, bioavailability and bioaccessibility through in vitro and in vivo assays on nuts and food products obtained from walnuts, such as almonds, walnuts, cashew nuts, pistachios, hazelnuts, walnuts, walnuts, macadamia nuts, Brazil nuts, pine nuts...
The recovery of phenolic antioxidants from agro‐industrial by‐products using non‐conventional techniques is a powerful tool to explore the bioactive potential of natural sources. Therefore, it is imperative to analyze the most suitable method to investigate a plant material’s phenolic composition. This study used ultra‐turrax (UTE), ultrasonic bath...
Antioxidant and antimicrobial properties, and chemical composition from Pleurotus sajor-caju extracts were evaluated from samples obtained by supercritical fluid extraction (SFE) and pressurized liquid extraction (PLE) with ethanol, and by sequential extraction (SE) combining the high-pressure methods. The performance of the SE was compared with th...
In this work, hybrid aerogel beads of sodium alginate (SA) and graphene oxide (GO) were synthesized by the external gelation method, dried by supercritical CO2, and applied for tartrazine removal from aqueous media. The effects of drying time, calcium chloride (CaCl2) and GO content on the aerogel properties were first investigated. The SA and SA-G...
Deep eutectic solvents (DES) are emergent solvents with high extractability of bioactive compounds. Therefore, anthocyanin rich-fractions were recovered from jaboticaba peels by combining aqueous solutions of DES and pressurized liquid extraction (PLE). The extraction occurred at 10 MPa, 12 min, with conditions optimized through response surface me...
Supercritical fluid extraction (SFE) and pressurized liquid extraction (PLE) were combined, in a biorefinery approach, to recover the nonpolar and polar fractions from tamarind seeds, which represent 25-40% of processed fruit. Total phenolic content (TPC), antioxidant capacity, and chemical composition were evaluated, and compared with values from...
Ora-pro-nobis (Pereskia aculeata) leaves were selected as raw material for biorefinery application based on compressed fluid extractions with green solvents. The fractionation followed the sequential processes: (1) Supercritical fluid extraction (SFE) with CO2, (2) Gas expanded liquid extraction (GXL), using CO2:Ethanol, and pressurized liquid extr...
In the last two decades, research on high value compounds such as lipids, including polyunsaturated fatty acids, sterols, phospholipids, as well as carotenoids and phenolic compounds has raised great attention, due to the increasing interest of consumers in functional foods which can promote health benefits. Microalgae, macroalgae, fisheries produc...
Ora-pro-nobis is an ornamental plant, often used as food in some regions of Brazil, and Pereskia grandifolia is one of the less explored specie of this nutritional plant. To understand the antioxidant potential and phenolic profile of ora-pro-nobis leaves, the micro-wave assisted extraction (MAE) was held using the green solvents ethanol and water....
Ora-pro-nobis (OPN) is an unconventional food plant used in some Brazilian regions in traditional culinary. A combination of high-pressure extraction processes was used, following the biorefinery concept, to value this underestimated raw material. A sequence of extractions was performed, with solvents of increasing polarity: supercritical fluid ext...
Background
Color is the first and most impacting attribute affecting directly the consumers preference, selection, and desire. Synthetic colorant ingredients are largely used by the food and pharmaceutical industries. However, there are concerns about the use of synthetic pigments due to their adverse health effects. These issues have increased the...
The purpose of this review is to demonstrate how the unexplored nuts native to Brazil can contribute positively to biodiversity and human nutrition. This review presents data on the composition of macronutrients, micronutrients, and bioactive compounds of non-conventional nuts native from Brazil (baru, chichá, gurguéia, monguba, pracaxi and sapucai...
Ora-pro-nobis (Pereskia aculeata), an emerging unconventional food plant belonging to the Cactaceae family, is known as a source of protein with high nutritional value, traditionally used in folk medicine. In this study, different compressed fluid technologies were used to obtain antioxidant rich extracts from P. aculeata leaves. The recovered extr...
In general, buriti seed (BSE) and buriti shell (BSH) are discarded or used as animal feed. However, these materials may have other destinations. Therefore, the aim of this work to was obtain extracts from BSE and BSH using different extraction techniques and solvents in order to evaluate their effect on phenolic profile and antioxidant capacity of...
Background
There is a high demand for food and pharmaceutical products enriched with natural compounds to replace synthetic additives, contributing to human health and the immune system. The jaboticaba (family Myrtaceae) is a Brazilian berry, little known and scarcely used, but with high biological potential, such as antioxidant, antimicrobial, ant...
Pachira aquatica Aubl. (munguba) seeds represent a rich source of lipids and biocompounds with potential for sustainable exploitation. This work evaluated the feasibility of using supercritical fluid extraction (SFE) and pressurized liquid extraction (PLE) to obtain a lipid-rich fraction and extracts rich in biocompounds from munguba seeds. The SFE...
Background
Polyphenols are an important group of bioactive compounds used as food ingredients and supplements. However, its application is limited because they have low water-solubility, bioavailability and stability in gastrointestinal fluids, aspects that can be modulated by polyphenols cocrystallization. Nevertheless, cocrystals have been mostly...
The dataset obtained in this work comprise original new data on the phase equilibrium of ternary systems CO2 + ethanol + quercetin (QCN), CO2 + ethanol + nicotinamide (NIC), and the quaternary system CO2 + ethanol + QCN + NIC with a molar ratio of 1:1 (QCN:NIC), which comprehension of phase behavior can be useful to establish experimental condition...
This study aimed to recover the anthocyanin-rich extract from broken black bean hulls by pressurized liquid extraction (PLE) and to study their chemical stability, inhibition capacity toward carbohydrate-enzymes and application in gelatin. A Box-Behnken design (BBD) coupled to response surface methodology (RSM) was applied in order to maximize the...
This work includes the second/sequential stage of a green-based valorization strategy of mango peel. An exhausted biomass from a pilot-scale CO2 supercritical extraction process was reused for obtaining phenolic-rich extracts with high antioxidant and anti-proliferative activity, employing microwave-assisted extraction. The effects of microwave pow...
![Hansen Solubility Parameters (HSP) of solvents obtained from [29].](profile/Mirelle-Dogenski/publication/344339364/figure/tbl1/AS:938547997601793@1600778688083/Hansen-Solubility-Parameters-HSP-of-solvents-obtained-from-29_Q320.jpg)
In this work, the ability of several solvents to induce gel formation from amylomaize starch solubilized in dimethyl sulfoxide (DMSO) was investigated. The formed gels were subjected to solvent exchange using ethanol and dried with supercritical carbon dioxide (sc-CO 2) to obtain the aerogels. The influence of starch concentration (3-15 wt%) and so...
Large-scale pressurized liquid extraction (PLE) data are scarce in literature, exposing the lack of information to support industrial projects. In this study, using Sida rhombifolia, the Sovová's model, developed for supercritical fluid extraction (SFE), was applied to describe PLE process, demonstrating good representation of experimental PLE data...
Laurel leaves essential oil is widely studied and valued due to its bioactive functions as antimicrobial, antifungal, antioxidant, antiviral, insecticide and food applications. Encapsulation may be an alternative for protection of their active components. Therefore, the objective of this work is to evaluate the influence of process variables of the...
Background
Peanut processing industries generate underused by-products (skin, shell and peanut meal) which still present high economic potential. Peanut shell has adsorbent potential for water treatment, as feedstock in biofuels and nanocarbon production, as well as source of bioactive compounds. Likewise, peanut skin is a potential source of carbo...
Integrated high-pressure processes, combining Supercritical CO2 extraction (SFE-CO2), Pressurized Liquid Extraction (PLE), and Subcritical Water Extraction (SWE), were used to obtain antioxidant compounds from pink pepper fruits. The recovered extracts were characterized in terms of total phenolic content (TPC) and antioxidant activity, by the meth...
Spice commerce is constantly growing, and peppers are among the most appreciated worldwide. Brazil is the second largest worldwide producer of black pepper. Many studies show that black pepper has antioxidant, anti-inflammatory and anti-tumor properties. Then, it is necessary to protect these active compounds of degradation agents, by microencapsul...
The spice commerce is constantly growing, and peppers are among the most appreciated worldwide. Brazil is the second largest worldwide producer of black pepper. Many studies show that black pepper has antioxidant, anti-inflammatory and anti-tumor properties. Pink pepper (Schinus terebinthifolius R.) is a Brazilian native tree, and commercialized al...
Chaya is a neglected, fast-growing and drought-resistant shrub, mostly cultivated in Mesoamerica as vegetable and medicinal plant. The increasing demand for safe products promotes processes with non-toxic solvents. In this context, Subcritical Water Extraction (SWE) and Microwave-Assisted Extraction (MAE) with ethanol were firstly applied to recove...
Controlling the degradation rates of polymers is crucial for their application in tissue engineering or to achieve degradation of the polymers in the wastewater purification. As hydrophobic polyesters often exhibit very slow degradation rates, we report here increased biodegradation rates of poly(globalide-co-ε-caprolactone) copolymers (PGlCL) prod...
In this work, in silico and experimental approaches were combined for the selection of starting compounds of NADES (Natural Deep Eutectic Solvents) aiming a selective and sequential extraction of anthocyanin and pectin from Myrciaria cauliflora by-product. Six NADES were prepared and characterized by DSC, pH, and rheological analysis. COSMO-RS was...
Sida rhombifolia extracts, obtained by pressurized liquid extraction (PLE), were microencapsulated in maltodextrin (MD) by spray drying. Different formulations were prepared with MD at 20% (w/w) and with 2.5, and 5.0% of S. rhombifolia extract, called ME2.5, and ME5.0, reaching an encapsulation efficiency of 89, and 94%, respectively. Scanning elec...
Pterodon spp. is a native Brazilian tree species of Fabaceae family, popularly known as sucupira. In the present study, the extraction methods of Soxhlet, supercritical fluid extraction (SFE) and ultrasound assisted extraction (UAE) were conducted at different conditions to recover compounds from “sucupira” with larvicidal activity against Aedes ae...
Background
Kappaphycus alvarezii is the 5th world's most cultivated macroalgae, since it is an essential source of carrageenan, widely used in food industry. However, K. alvarezii is an unexplored biomass for green biorefinery conversion, since its composition includes valuable proteins, lipids, phenolic compounds, among others. Although there are...
The growing interest in producing biocompatible polymers, free of any kind of toxic residues, increasingly encourages the development of researches on clean processes. The use of supercritical carbon dioxide (scCO2), replacing organic solvents, has shown to be a green alternative to traditional polymerization processes. In order to establish better...
In this work, starch-based aerogels incorporated with agar or microcrystalline cellulose (MCC) were obtained via thermal gelation in aqueous media, retrogradation, solvent exchange using ethanol, and supercritical drying with carbon dioxide (CO2). The influence of starch concentration (10 and 15 wt%), agar or MCC addition (0, 0.25, 0.5, and 1 wt%),...
Extracts with biological activities need to be preserved, as they can be degraded if exposed to light or heat. This work reports results of microparticles formation of yacon leaf extract with modified maize starch as encapsulated agent using Supercritical Fluid Extraction of Emulsions (SFEE). The variable investigated were pressure (9 to 13 MPa) an...
Pink pepper presents nutritional importance and properties such as anti-inflammatory and antioxidant activities. To protect these beneficial characteristics, the plant extracts can be encapsulated, where system phase equilibrium behavior for carbon dioxide, dichloromethane (DCM) and pink pepper extract (PPE) was investigated to establish optimal en...
The Amazonian tree Pentaclethra macroloba (pracaxi) has pod-shaped fruits with flattened seeds mostly composed of lipids, carbohydrates, and proteins, besides secondary compounds, which provide potential use by many industries. This study evaluated the supercritical carbon dioxide (SC–CO2) extraction of pracaxi seed oil (PSO) at different condition...
Fundamentos de Engenharia de Alimentos, ora em sua 2ª edição, encontra-se integralmente revisto e atualizado. Foram inseridos links de programas para cálculos de propriedades termodinâmicas. Acrescentaram-se novas discussões e novos exemplos. O livro tem como público alunos dos cursos de Engenharia de Alimentos, Ciência de Alimentos, Nutrição e Far...
The present work shows that mango peel is an agro-industrial residue with high nutraceutical value, and a suitable separation process was evaluated for the best extraction of its bioactive content. The objective of the present work was to analyse the phenolic profile and in vitro antioxidant activity (AOX) of extracts from mango peel obtained by lo...
The recovery of high-value compounds from Sida rhombifolia, integrating supercritical fluids extraction (SFE) and pressurized liquids extraction (PLE) in a biorefinery approach, provides a better use for the raw material with reduced energy consumption. The aim of this work was to study the effect of the SFE depressurization flow rate to improve th...
The novelty of this study was the use of a subcritical water unit to recover phenolic compounds from papaya seeds, a relevant agroindustrial waste. The effect of temperature conditions on subcritical water extraction (SWE) was compared to Soxhlet extraction (SOX) in terms of total yield, phenolic content (TPC), Maillard reaction products (MRPs), an...
When nanoparticles (NPs) are introduced to a biological fluid, different proteins (and other biomolecules) rapidly get adsorbed onto their surface, forming a protein corona capable of giving to the NPs a new “identity” and determine their biological fate. Protein–nanoparticle conjugation can be used in order to promote specific interactions between...
The development of bioresorbable polymeric materials for medical applications has advanced considerably during the last decades, aiming the development of safer and more effective health treatments. Furthermore, studying the use of clean technologies for the production of polymers for biomedical applications is extremely relevant, given the need of...
Mauritia flexuosa (buriti) is considered the most popularly palm tree. The oil obtained from buriti maybe an alternative to obtain tocopherols, carotenoids and monounsaturated fatty acids. Among the vegetable oils, the buriti oil is the one that presents the highest concentration of carotenes and your pulp stands out like as one of the main sources...
Quercetin (QUE) is a natural polyphenol with strong biological properties, such as antidiabetic, anticancer and anti-obesity effects. However, the application of quercetin as a food supplement is limited due to its low solubility and bioavailability. Cocrystallization is a potential procedure to improve physicochemical properties of a target molecu...
Beetroot (Beta vulgaris L.) residues, leaves and stems, normally disposed as animal feed or compost, were investigated for the recovery of valuable compounds by pressurized liquid extraction (PLE) at temperature of 40 °C and pressures of 7.5, 10 and 12.5 MPa, and flow rate of 3 mL min⁻¹. This abundant residue, combined with the lack of related stud...
Background
Bioactive compounds have been intensely studied because of their biological properties that provide health benefits. However, for chemical or biological applications, these compounds are obtained mostly by using organic solvents. Emergent technologies consider the combination of methods and process optimization to improve the utilization...
Buriti fruit, with high content in carotenoids and antioxidant compounds, is well appreciated for its organoleptic characteristics. However, its shell, an agroindustrial residue, is mostly discarded. Therefore, to verify the technological potential of the buriti shells, the aim of this this study was to evaluated the antioxidant potential of the ex...
Supercritical fluid technologies offer an innovative method for food industry and drug discovery from natural sources. The aim of the study is to investigate the anti-tumor activity of piperine rich extract by supercritical fluid (SFE) from black pepper (Piper nigrum). In silico docking simulations predicted anti-tumor molecular mechanism and prote...
In this work, supercritical fluid extraction (SFE) for the recovery of phenolic antioxidants from papaya agroindustrial waste (seeds) was explored, making use of neat supercritical CO2 and CO2 added with ethanol (CO2-EtOH). A full factorial design played on in order to evaluate the effect of CO2 extraction parameters (temperature between 40 and 60...
As sementes de pracaxi (Pentaclethra macroloba (Willd.) Kuntze) possuem elevado conteúdo de lipídeos e são usadas para extração de um óleo apreciado por sua composição química. Extrações assistidas por fluidos pressurizados são consideradas tecnologias verdes que não agridem o meio ambiente, respeitam o tripé da sustentabilidade e são cada vez mais...
A árvore amazônica Pentaclethra macroloba (Willd.) Kuntze, da família Fabaceae, conhecida como pracaxi, ocorre naturalmente em muitos países das Américas Central e do Sul, inclusive no Brasil. Os frutos desta árvore, em forma de vagem, possuem
sementes que apresentam até 51% de lipídios. A aplicação de dióxido de
carbono supercrítico (SC-CO2) é um...
Beetroot is a well appreciated edible root, widely used for sugar and ethanol production, and source of natural colorant. Its aerial parts, leaves and stems, are frequently discarded as animal feed or manure. Therefore, the recovery of bioactive components from these materials is appealing due to abundance of raw material, its low price and poor va...
Essential oil of laurel leaves presents, as the main component, the bioactive 1,8-cineole. The Supercritical Fluid Extraction of Emulsions (SFEE) is an alternative method for the encapsulation of natural substances, such as laurel essential oil, particularly allied with the ultrasound technique, which has been promising for the formation of emulsio...
The fruit of Spondias tuberosa (umbu) is widely consumed in the northeast region of Brazil. In this work, the potential of umbu seeds as source of bioactive compounds was evaluated. Different extraction techniques were compared in terms of yield, free-fatty acids composition, total phenolic content (TPC) and antioxidant activity (AA). The extractio...
Integrated downstream processes, combining Supercritical Fluid Extraction (SFE) with Pressurized Liquid Extraction (PLE), were used to recover antioxidants from Sida rhombifolia leaves. The SFE depressurization step was evaluated to improve PLE efficiency in the recovery of phenolic compounds. Total phenolic content of the extracts was performed by...
The control of coke deposition is one of the most important challenges during reforming processes using Ni/Al 2 O 3 catalysts. To minimize the effects of coke deactivation and increase the catalytic performance, Ni–Y 2 O 3 –Al 2 O 3 aerogel catalysts were synthesized by the epoxide-initiated gelation method and dried with supercritical CO 2 . The c...
Guava (Psidium guajava L.), a popular fruit in tropical countries, can be consumed in natura or transformed into many products. Guava's processing waste (seed, peel, and pulp leftovers) can represent up to 30% of the fruit's volume. Evidence indicates that this fraction still holds a significant amount of antioxidant substances, such as phenolic co...
N-Acetylcysteine (NAC) is a drug well known for its antimucolytic action, antioxidant activity and ability to protect cells from oxidative stress. Conjugation of NAC with double bonds in the main polymer chain of poly(globalide-co-ε-caprolactone) (PGlCL) through thiol-ene reaction is reported. Different globalide (Gl) (an unsaturated macrolactone)...
Cajazeira leaves (Spondias mombin) have their highlighted use as antioxidant and natural antimicrobial, which justifies the objective of this work to evaluate the biological activities of different extracts. In order to evaluate the antioxidant and antimicrobial potentials of the cajazeira leaves, extractions at low pressure and high pressure were...
Nowadays, food waste valorization is under intense worldwide investigation. In this framework, bioactive compounds from papaya seeds were recovered by supercritical extraction to evaluate the process variables effect in extraction kinetics. A computational code MSEM (MatLab Simulation Extraction Models) was developed to represent different mass tra...
