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Introduction
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Publications
Publications (20)
Citation: Álvarez-Salvago, F.; Figueroa-Mayordomo, M.; Molina-García, C.; Pujol-Fuentes, C.; Atienzar-Aroca, S.; de Diego-Moreno, M.; Medina-Luque, J. Assessing the Relationship of Different Levels of Pain to the Health Status of Long-Term Breast Cancer Survivors: A Cross-Sectional Study. Life 2025, 15, 177. https://doi. Abstract: Purpose: This stu...
Purpose
This study aimed to assess pain, fitness condition, physical activity (PA) level, comorbidities, cancer-related fatigue (CRF), mood state and health-related quality of life (HRQoL) in long-term breast cancer survivors (LTBCS) compared to women without cancer history, matched by age, weight, height, and educational level.
Methods
A cross-se...
Fisiología del Sistema Estomatognático es una asignatura de carácter básico en el plan de estudios del grado en Odontología y es imprescindible para que los estudiantes comprendan, entre otros conceptos, las funciones de los tejidos y músculos orofaciales. Sin embargo, esta asignatura puede resultar compleja y con una alta cantidad de contenidos pa...
Purpose
The aims of this study were to evaluate whether the effects of two therapeutic exercise programs are sustained over time (≥ 5 years) in long-term breast cancer survivors (LTBCS). Second, to determine the influence of the current level of physical activity (PA) performed on cancer-related fatigue (CRF) that these patients may present ≥5 year...
Autophagy and exosome secretion play important roles in a variety of physiological and disease states, including the development of age‐related macular degeneration. Previous studies have demonstrated that these cellular mechanisms share common pathways of activation. Low oxidative damage in ARPE‐19 cells, alters both autophagy and exosome biogenes...
The retinal pigment epithelium (RPE), a monolayer located between the photoreceptors and the choroid, is constantly damaged by oxidative stress, particularly because of reactive oxygen species (ROS). As the RPE, because of its physiological functions, is essential for the survival of the retina, any sustained damage may consequently lead to loss of...
Purpose:
Cytochrome p450 2E1 (CYP2E1) is a detoxifying enzyme with particular affinity for ethanol (EtOH) expressed in several tissues. Although CYP2E1 has been identified in human RPE, nothing is known about its metabolic activity. Expression of CYP2E1 and activity after EtOH exposure have been studied in human RPE and ARPE-19 cells.
Methods:
E...
Diabetes and alcohol misuse are two of the major challenges in health systems worldwide. These two diseases finally affect several organs and systems including the central nervous system. Hippocampus is one of the most relevant structures due to neurogenesis and memory-related processing among other functions. The present review focuses on the comm...
Organisms harbor a variety of molecules and enzymes which are members of a vast array of antioxidating networks in maintaining their physiological redox balance. Superoxide dismutase (SOD) family members are employed for their adaptation to various environmental stresses in order to survive. Superoxide anion is produced inside the cell as a result...
We discuss the participation of mitochondrial dynamics and autophagy in the 6-hydroxidopamine-induced Parkinson's disease model. The regulation of dynamic mitochondrial processes such as fusion, fission, and mitophagy has been shown to be an important mechanism controlling cellular fate. An imbalance in mitochondrial dynamics may contribute to both...
