Sandeep Negi

Indian Institute of Toxicology Research | IITR · Animal Facility

Aromatherapy is a medical practice that uses aromatic compounds or essential oils to influence mood and health. Essential oils used in aromatherapy are created from a wide variety of medicinal plants, flowers, herbs, roots, and trees that are found all over the world and have significant, well-documented benefits on enhancing physical, emotional, a...

Aromatherapy is a medical practice that uses aromatic compounds or essential oils to influence mood and health. Essential oils used in aromatherapy are created from a wide variety of medicinal plants, flowers, herbs, roots, and trees that are found all over the world and have significant, well-documented benefits on enhancing physical, emotional, a...

Aromatherapy is a medical practice that uses aromatic compounds or essential oils to influence mood and health. Essential oils used in aromatherapy are created from a wide variety of medicinal plants, flowers, herbs, roots, and trees that are found all over the world and have significant, well-documented benefits on enhancing physical, emotional, a...

The aim of the present study is to characterize the inorganic and organic contaminant loads in hazardous TWW and their effects on a number of biochemical and haematological changes in Swiss mice at four concentrations: C (control purified water), L(low 2.5% TWW), M(medium 5.0% TWW), and H(high 10% TWW). Significant differences were observed in the...

Antibiotic resistance in the last decade has recorded drastic changes in an increasing manner in nonfermenting bacterial groups of gram‑negative bacilli including Ps. aeruginosa is a potent bacterial isolate or opportunistic nosocomial human pathogen. In recent decades, with improvements in antimicrobial therapy and diagnostic procedures have emerg...

Tattooing is a very common fashion trend across all the ages and gender of the society worldwide. Although skin inflammatory diseases are very frequent among tattoo users because of the active chemical ingredients used in tattoo ink, yet no ingredient-specific toxicity study has been performed. Benzo(ghi)perylene (BgP) is one of the PAHs and an imp...

Tattooing on different parts of the body is a very common fashion trend in all sections of society globally. Skin allergies and other related skin diseases are very common among tattoo users. Benzo[ghi]perylene (BP) is a PAH and an important component of tattoo ink that showed prominent absorption under ultraviolet radiation (UVR) region. Therefore...

Today, tattooing has become very popular among people all over the world. Tattooists, with the help of tiny needles, place tattoo ink inside the skin surface and unintentionally introduce a large number of unknown ingredients. These ingredients include polycyclic aromatic hydrocarbons (PAHs), heavy metals, and primary aromatic amines (PAAs), which...

2,4,5,6-Tetraaminopyrimidine sulfate (TAPS) is worldwide the most commonly used developer in hair dyes. As skin is the major organ, which is directly exposed to these permanent hair dyes, a comprehensive dermal safety assessment is needed. Hereto, we studied the photosensitization potential and mechanism involved in dermal phototoxicity of TAPS exp...

Background: Subacute thyroiditis is a viral or postviral thyroid disease.The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak, which began in Wuhan, China, has spread fast throughout the world, also affected almost all states of India. Objectives: The present work is the first report of Subacute thyroiditis after SARS-CoV-2 Inf...

Today, we are living in the era of Coronavirus Disease-2019 (COVID-19), a pandemic that has affected almost the whole globe. It has rightly been called as the ‘twenty-first-century plague’ which has garnered considerable attention from researchers, pharma companies, policymakers, and media. Though vaccines are being deployed and people are eagerly...

A significant proportion of nosocomial infections is contributed by the Major changes were observed from time to time in prevalence and multidrug-resistant (MDR) with enormous morbidity and mortality. The spread of antimicrobial resistance has now become a worldwide issue as a consequence of the haphazard use of antimicrobials. This study was done...

Background: Infections due to Klebsiella sp. comes under nosocomial infections. These are difficult to treat due to the multiple drug resistance acquired by organisms. The present study was done to know the antibiotic resistance pattern of Klebsiella sp. isolated from different clinical samples collected at the tertiary care centre of Garhwal Himal...

Corona virus disease 2019 (COVID-19) is primarily caused by Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). The infection begins with flu like symptoms with respiratory problems but in severe cases it affects cardiovascular system and excretory systems. On March 11, 2020 World Health organization (WHO) announced this disease as pandem...

Prolonged exposure of the earth's surface to the sun's ultraviolet radiation may result in various skin diseases and cataract. Carbazole (CBZ), as a polycyclic-aromatic hydrocarbon (PAH), is blended with a five-member nitrogen-containing ring. It is found in cigarette smoke, coal, eye kohl, tattoo ink, and wood combustion and affects various types...

Biotechnology

Chapter on Blood,its composition,its formation and its important functions in our body.

Care and maintenance of Laboratory Animals

Care of Laboratory Animals

PAHs or polycyclic aromatic hydrocarbons belong to group of environmental pollutants which come under human carcinogens. PAHs is a class which refers to an immensely colossal number carbon and hydrogen along with two or more fused aromatic rings. These PAHs produced from chemicals occur naturally in coal, crude oil, and gasoline. The physical prope...

Cosmetics are chemical substances or products that are used to change the look or fragrance of the human beings. Mostly cosmetics are applied usually on the face and hair area. Sun acts as a natural source of different wavelengths that also contains ultraviolet (UV-A, UV-B, and UV-C) and many other radiations. Many ingredients present in cosmetics...

protection of human health from the use of cosmetics products

CSIR-IITR, Lucknow

Introduction: Typhoid fever is endemic in all parts of India and the Widal test is widely used for its diagnosis. In the endemic areas, the healthy people may contain antibodies which are capable of reacting upto a variable titre in the Widal test, due to a past exposure, TAB vaccination and cross reacting antigens. Therefore it varies widely from...

Introduction: Typhoid fever is endemic in all parts of India and the Widal test is widely used for its diagnosis. In the endemic areas, the healthy people may contain antibodies which are ca-pable of reacting upto a variable titre in the Widal test, due to a past exposure, TAB vaccination and cross reacting antigens. Therefore it varies widely from...