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Introduction
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Publications
Publications (12)
Missing or inaccessible lung function measurements, gathered over time, have the potential to stagnate or impair clinical care decisions being made. This jeopardises patient safety and often contributes to excessive resource utilisation. Data integration is fundamental to clinical decision-making and entails amalgamating lung function data from mul...
Environmental air pollution presents a considerable risk to global respiratory health. If critical levels are exceeded, inhaled pollutants can lead to the development of respiratory dysfunction and provoke exacerbation in those with pre‐existing chronic respiratory disease. Over 90% of the global population currently reside in areas where environme...
Introduction
The composite physiological index (CPI) is designed to estimate the extent of fibrosis on a thoracic CT and has been shown to be the best physiological prognosticator in idiopathic pulmonary fibrosis (IPF). However, the transferability of the CPI to other forms of interstitial lung disease (ILD) are less well-understood. The aim of thi...
Objective:
Elexacaftor/Tezacaftor/Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator with the potential to improve exercise capacity. This case series of three adolescents with CF aimed to investigate whether 6 weeks treatment with Elexacaftor/Tezacaftor/Ivacaftor could improve exercise capacity in CFTR modulator n...
This study investigated whether Elexacaftor-Tezacaftor-Ivacaftor (Kaftrio ), a cystic fibrosis (CF) transmembrane conductance regulator (CFTR) modulator, could improve exercise capacity in adolescents with CF. After six weeks treatment, Kaftrio improved both maximal and submaximal indices of aerobic fitness. Improvements were independent of changes...
Background:
The development of cystic fibrosis (CF)-related diabetes (CFRD) in paediatric groups is associated with a reduced aerobic fitness. However, this has yet to be investigated in adults with more severe lung disease.
Methods:
Cardiopulmonary exercise and glycaemic control tests were retrospectively analysed in 46 adults with CF (age: 26....