Samuel Martin-Fonseca

Samuel Martin-Fonseca
University of Granada | UGR · Department of Organic Chemistry

PhD. Chemistry

About

7
Publications
2,086
Reads
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148
Citations
Additional affiliations
June 2014 - present
University of Granada
Position
  • PostDoc Position
Description
  • Natural Products Chemistry. Solid and liquid phase organic chemistry. Isolation and biological propertiers.
January 2012 - May 2014
University of Granada
Position
  • Researcher
January 2010 - December 2011
Biomaslinic S.L.
Position
  • Senior Researcher
Education
January 2011 - May 2014
University of Granada
Field of study
  • Organic Chemistry
October 2007 - December 2008
University of Granada
Field of study
  • Biochemistry
October 2001 - February 2007
University of Granada
Field of study
  • Chemistry

Publications

Publications (7)
Article
Maslinic acid (2α,3β-dihydroxyolean-12-en-28-oic acid), a natural dihydroxylated pentacyclic triterpene acid isolated from olive-pressing residues, has been investigated together with some of its derivatives regarding the induction of apoptosis in B16F10 melanoma cells. Some of the compounds tested are described in this work, but others come from p...
Article
Oleanolic acid (1) pentacyclic triterpene present in olive pomace, is known to induce apoptosis and to be anti-tumor, but high concentrations of this product are necessary to produce its cytotoxic effects. The 3-O-succinyl-28-O-benzyl oleanolate derivative (4), present a greater cytotoxicity and apoptosis effects than its natural precursor, oleanol...
Poster
Full-text available
PEGylation defines the modification of a protein, peptide or non-peptide molecule by the linking of one or more polyethylene glycol (PEG) chains. The PEG-molecule conjugates have several advantages: a prolonged residence in body, a decreased degradation by metabolic enzymes and a reduction or elimination of protein immunogenicity. This versatile te...

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