Samu LehtonenUniversity of Eastern Finland | UEF · School of Medicine
Samu Lehtonen
Doctor of Medicine | Bachelor of Science (Technology)
About
4
Publications
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Introduction
In my PhD studies, I research spectral imaging and its microneurosurgical applications. Microsurgery Center of Eastern Finland conducts research in microsurgical techniques, medical photonics and CNS pathologies while functioning as a testing platform for new healthcare innovations.
https://www.microsurgerycenter.com/
Publications
Publications (4)
BACKGROUND
The first-line treatment for high-grade gliomas (HGG) is maximal safe resection, which is limited by diffuse tumor margins and nearby eloquent areas. Intraoperative detection of tumor cells is improved with fluorescence-guided surgery using 5-ALA, but its visual detection is limited by blood, obstacles and weakness of the fluorescence. A...
Background
: 5-aminolevulinic acid (5-ALA) – precursor of protoporphyrin IX (PpIX) – is utilized in fluorescence guided surgery (FGS) of high-grade gliomas. PpIX is used to identify traces of glioma during resection. Visual inspection of the fluorescence seems inaccurate in comparison to optic techniques such as hyperspectral imaging (HSI).
Aim
:...