Samson Nivins

Samson Nivins
Karolinska Institutet | KI · Department of Neuroscience

M.S (specialized in Neuroradiology) Ph.D (Perinatal Neuro)

About

35
Publications
28,022
Reads
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27
Citations
Citations since 2016
26 Research Items
27 Citations
201620172018201920202021202202468101214
201620172018201920202021202202468101214
201620172018201920202021202202468101214
201620172018201920202021202202468101214
Introduction
An aspiring Neuroscientist with an extensive interest towards neonatal and paediatric neurology, and interested in understanding the neural activity associated with developmental performance.
Additional affiliations
January 2019 - February 2022
University of Auckland
Position
  • PhD
Description
  • Perinatal Intervention Neurology- CHYLD9 DIAMOND Babies
October 2015 - October 2018
Neurogen Brain and Spine Institute
Neurogen Brain and Spine Institute
Position
  • Fellow
Description
  • Neuro-radiology- Clinical Investigator and diagnosing Neurological disorder
September 2015 - October 2018
Nueclear Healthcare ltd/ Swastik Diagnostic Centre/ MPCT hospital
Position
  • Associated
Description
  • CT/MRI/PET
Education
February 2019 - January 2022
University of Auckland
Field of study
  • Perinatal Neuro
December 2014 - August 2015
Karolinska Institutet
Field of study
  • Neuroradiology

Publications

Publications (35)
Preprint
Full-text available
Digital media takes an increasingly large part of children’s time, however, the long-term effect on brain development is unclear. Here, we investigated the individual effects of digital media use (watching television and videos, using social media, or playing video games, respectively), while controlling for genetic predisposition and socioeconomic...
Preprint
Full-text available
Digital media takes an increasingly large part of childrens time; however, the long-term effect on brain development is unclear. Here, we investigated the individual effects of digital media use (watching television and videos, using social media, or playing video games, respectively) while controlling for genetic predisposition and socioeconomic s...
Article
Importance: Neonatal hypoglycemia is associated with increased risk of poor executive and visual-motor function, but implications for later learning are uncertain. Objective: To test the hypothesis that neonatal hypoglycemia is associated with educational performance at age 9 to 10 years. Design, setting, and participants: Prospective cohort s...
Article
Full-text available
Neonatal hypoglycaemia is a common metabolic disorder that may cause brain damage, most visible in parieto-occipital regions on MRI in the acute phase. However, the long term effects of neonatal hypoglycaemia on the brain are not well understood. We investigated the association between neonatal hypoglycaemia and brain volumes, cortical thickness an...
Article
Full-text available
Intellectual disabilities (ID) are neurodevelopmental disorders characterized by deficits in intellectual functioning and adaptive behavior which includes conceptual, social and practical skills. 1 out of 4 individuals with ID have co-existing autism spectrum disorder (ASD). Recently, cell therapy has shown great potential in management of ID with...
Article
Full-text available
Brain undergoes most of the dynamic change in utero and the developmental changes continue over the first two postnatal years of life. Early phase of life is very crucial as neurodevelopmental disorder such as Autism, ADHD are likely to be noticeable during the first years of life. Better understanding of normal brain pattern is necessary for ident...
Poster
Full-text available
Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disorder of upper and lower motor neurons. The motor neurons in the prmary motor cortex, project their axons caudally along the corticospinal tract through the brainstem to the spinal cord, where they synapse onto the anterior horn cells. Progressive degenerationof motor neurons results in...
Preprint
Full-text available
Adults with autism spectrum disorder (ASD) experience significant impairments in social interaction, poor planning, decision making, timing and motor skills which impact on their daily activities of living and ability to access the health care services. Early research on ASD primarily focused on children with service provision for adults is still i...
Article
Full-text available
Alzheimer's Dementia (AD) is a progressive neurodegenerative disorder and is one of the most common causes of dementia in older adults. The pathology of AD is characterized by intracellular neurofibrillary tangles and amyloid plaques in the extracellular space. Herein, we describe a case of a 51-year-old woman who complained of behavioural changes...
Book
Full-text available
Guide for ALS patient- Blink to Speak
Article
Full-text available
[18F] 2-fluoro-2-deoxy-D-glucose positron emission tomography-computed tomography scan was performed on 45 children with autism to study the baseline pattern and age-related developmental changes in the brain metabolism. Median standardized uptake values (SUVs) were compared with published healthy control data. Results showed that, in contrary to c...
Article
Full-text available
Duchenne muscular dystrophy is the commonest and the most devastating of the muscular dystrophies. With no known cure, new advances, such as gene therapy, exon skipping and cell therapy are being explored as treatment options. Gene therapy using viral and non-viral vectors is however, restricted due to safety issues. Although a drug, eteplirsen, ha...
Article
Full-text available
Cerebral palsy (CP) is an umbrella term including a group of permanent disorders of development of movement and of posture causing activity limitation. Oxidative stress and glutamate mediated excitotoxicity are important mechanisms of injury to both the white matter and neurons in the developing brain resulting in motor deficits. No treatment measu...
Article
Full-text available
Background The underlying pathophysiology in intellectual disability (ID) involves abnormalities in dendritic branching and connectivity of the neuronal network. This limits the ability of the brain to process information. Conceptually, cellular therapy through its neurorestorative and neuroregenerative properties can counteract these pathogenetic...
Article
Background: Cerebral palsy (CP) is a non-progressive disorder. The global incidence of neonatal CP is 1-5 per 1000 live births where 45% of children with CP have a comorbid intellectual disability (ID). This affects the quality of life and reduces life expectancy of affected individuals. Methods and findings: With an aim to study the efficacy and...
Poster
Full-text available
In our study, we found that 39 of the total 50 (78%) ALS patients had plasma TT levels lower than the mean levels in age matched healthy males. We also found a decline in TT levels with disease progression as seen on ALSFRS-R and King's staging. Low levels of total testosterone may put neurons at a risk of damage and may be a contributing factor to...
Article
Full-text available
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder affecting communication, behavior and socialization. The exact etiology is unknown, but combination of genetic, environmental, and immunological factors is likely to be responsible for ASD. Autologous bone marrow mononuclear cells (BMMNCs) have been studied in great detail and...
Article
Full-text available
Functional Magnetic Resonance Imaging (fMRI) is a non-invasive technique to monitor brain activity that provides detailed maps of the brain areas. A number of task-induced fMRI studies have demonstrated rearrangement of cortical activation patterns in the secondary brain areas in SCI patients. Chronic spinal cord injury (SCI) is a devastating disor...
Article
Full-text available
Spinal cord injury (SCI) in the pediatric population is a rare incidence and has devastating consequences. Cellular transplantation is one of the emerging strategies in the treatment of SCI. Here, we present a case report of an 8-year-old female who sustained traumatic incomplete SCI at the level of D10-D11 four years ago. Two years after the accid...
Article
Full-text available
Traumatic Brain Injury (TBI) is defined as an injury to the brain parenchyma resulting in neurological deficit following a trauma. Cell transplantation has evolved as a novel treatment modality in the management of TBI. Autologous Bone Marrow Mononuclear Cells (BMMNCs) have shown beneficial effects in the functional recovery of neurological deficit...
Raw Data
FDG-PET showing metabolic uptake in subcutaneous fat for HIV patient
Presentation
Full-text available
AD
Article
Medical images are extensively used by the doctors and researchers to find presence of abnormalities in human bodies and upgrading available technique respectively. This paper gives a technique for detection of brain tumor from Magnetic Resonance Imaging (MRI). MRI is an imaging tool used to identify and picture better-quality details of the intern...
Article
Full-text available
The most common disease among women is Breast cancer. The advancement in three dimensional ultrasound imaging has found a wide application in breast cancer detection. Even though 3-D ultrasounds provide structural information of abnormal tissue, manual diagnosis requires an expertise medical staff because of the extensive visual complexity. Therefo...
Conference Paper
Full-text available
In our proposed system 3-D reconstruction from 2-D cone beam projections using Feldkamp, Davis and Kress (FDK) the most widely used algorithm for it’s effective, spatial resolution and duration time. This reconstruction algorithm involves the control of source and detector using the Stepper motor in equidistant with respect to the object. The phant...
Conference Paper
Electromagnetic radiation in the range of near infrared light is widely used in the study of anatomical and the physiological research of the deep biological tissues. In Our proposed system we use Diffused optical tomography (DOT) which involves tomographic reconstruction of the isotropic diffusion of the near infrared light in the living tissues....
Conference Paper
Full-text available
The Cone Beam CT has been widely implemented in the field of medical and industry. The Cone beam CT reconstruction uses FDK algorithm for the reconstruction of projection images which are obtained at various angles by the detector. In our proposed system we use a matrix array of 830nm Infrared source, high intensity and power for examining the prop...
Conference Paper
Full-text available
The Cone Beam CT has been widely implemented in the field of medical and industry. The Cone beam CT reconstruction uses FDK algorithm for the reconstruction of projection images which are obtained at various angles by the detector. In our proposed system we use a matrix array of 830nm Infrared source, high intensity and power for examining the prop...
Article
Full-text available
The improvement and quality of the life of the patient is more important in the world. As the person’s age is increasing the ability of the persons to get attracted towards the disease also keeps on increasing. Therefore by providing a proper and improved techniques which helps in getting rid from that sort of disorder and could able to prevent the...
Article
Full-text available
Time and frequency domain features of the surface electromyogram (EMG) signal acquired from multiple channels have frequently been investigated for use in controlling upper-limb prostheses. We propose the use of EMG signal whitening as a pre-processing step in EMG-based motion classification. Whitening decor relates the EMG signal and has been show...
Conference Paper
Full-text available
Electromagnetic radiation in the range of near infrared light is widely used in the study of anatomical and the physiological research of the deep biological tissues. In this we use Diffused optical tomography (DOT) which involves tomographic reconstruction of the isotropic diffusion of the near infrared light in the living tissues. This helps in d...

Questions

Questions (15)
Question
I am quantifying MR volume for paediatrics using FS. However, I am encountering error specifically to Insular cortex probably because of maturation. While other regions are traced properly, can we use other lobes???
Cheers
Question
I am new to freesurfer, I have successfully processed few subjects, but have encountered with doubt regarding the output stats, which we get through freesurfer.
In aseg.stats, we get multiple columns with include Voxels, Volume, normMean, normStdDev, nomMin, normMax, normRange?
Does these norm is related to normalised to the specific region like ICV?
Thanks in advance

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