About
48
Publications
8,415
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
183
Citations
Introduction
I am a medical graduate, graduated from the Faculty of Medicine, University of Ruhuna in 1991. I obtained a PhD degree on Cardiovascular Physiology from the same University in 2002 (with the research component being carried out in University of California Davis, USA). I work as an academic staff member of the Department of Physiology, Faculty of Medicine, University of Ruhuna from 1994 up to now. Currently I am the Chair Professor of Physiology.
Skills and Expertise
Current institution
Additional affiliations
March 2018 - present
Position
- Chair Professor of Physiology (Senior Professor)
Description
- As the Chair Professor of Physiology, I have a big responsibility on the smooth conduct of the academic programme.
January 1997 - December 2000
May 1994 - November 2015
Faculty of Medicine, University of Ruhuna, Galle
Position
- Lecturer, Senior Lecturer, Professor
Publications
Publications (48)
Objectives
Bicipital tendinopathy (BT) is considered one of the major differential diagnoses of anterior shoulder pain, often accompanied by a restricted or painful range of motion (ROM). Our objective was to assess the effectiveness of myofascial release (MFR) in alleviating pain and improving ROM in patients with BT.
Materials and Methods
Sixty...
Objectives
Globally, undiagnosed cardiovascular anomalies are the primary cause of sudden cardiac deaths among school athletes. In Sri Lanka, data on this subject remain scarce. Recent fatalities involving adolescent athletes have highlighted the need for preventive measures to be introduced by the country’s healthcare sector. The aims and objectiv...
Introduction
Sodium fluoride (NaF), an antiglycolytic agent, is added to blood samples to prevent consumption of
glucose by red cells which may potentially reduce plasma glucose readings. Although widely used, a recent
study showed that NaF takes 3-4 hours to be fully effective in blocking glycolysis, as it blocks the enzyme
enolase which is locate...
Introduction and Objectives: Iliotibial Band Syndrome (ITBS) is a common overuse injury in athletes, primarily impacting the knee and hip due to repetitive friction of the iliotibial band against the femur, resulting in pain and restricted hip abduction and knee extension. Muscle power and pain associated with ITBS can be measured using Hand-held D...
Objectives: The iliotibial band (ITB) is a thick fascial band formed near the hip by merging the fascia of the gluteus maximus, gluteus medius, and tensor fasciae latae muscles. Iliotibial band syndrome (ITBS) is a common overuse injury, manifests as pain on the outer side of the knee and hip due to ITB friction with the femur. Athletes may experie...
Objectives: Bicipital tendinopathy causes shoulder pain and reduced range of motion (ROM). Analgesics and physiotherapy are used as treatments. The objective is to study the effectiveness of myofascial release for bicipital tendinopathy.Methods: Sixty patients with anterior shoulder pain were randomly allocated to control and experimental groups (n...
Cardiac arrest is a sudden loss of heart function with serious consequences. In developing countries, healthcare professionals use clinical documentation to track patient information. These data are used to predict the development of cardiac arrest. We published a dataset through open access to advance the research domain. While using this dataset,...
Annual Research Symposium PGIM Abstract book - Abstract no. 20 , page 20
Pulmonary Function Test Abnormalities in Patients with Rheumatoid Arthritis; A single center study at a Teaching Hospital in Sri Lanka
UK Egodage1, Darshana ILAN 2, S Gunawardena1, K Deshapriya3, HMA Ediriweera3, WMCD Wijekoon1
1 Department of physiology, Faculty of Medicine,University of Ruhuna, Sri Lanka
2. Department of Community Medicine, Facu...
Objective To evaluate the association between self-perceived level of information technology skills and performance in a self-directed learning-based assessment in 1 st year medical students Background
Abstract
Introduction
Pulmonary diseases are common extraarticular
manifestations of rheumatoid arthritis
(RA) and account for high disease related
mortality. Pulmonary function tests (PFTs) are
considered one of the cost-effective options for
early identification of pulmonary involvement
in RA.
Objectives
The objective of this study was to assess...
https://www.minervamedica.it/en/journals/gazzetta-medica-italiana/article.php?cod=R22Y2022N07A0552
Gazzetta Medica Italiana - Archivio per le Scienze Mediche 2022 July-August;181(7-8):552-7
DOI: 10.23736/S0393-3660.21.04674-X
Copyright © 2021 EDIZIONI MINERVA MEDICA
language: English
Use of fiber optic goniometer to objectively assess the angle an...
Background Cardiac arrest is an instantaneous loss of cardiac function in a person who may or may not be diagnosed with heart disease, and it has a significant impact on a patient’s well-being and can also pose a threat to their life. This retrospective cohort study evaluates patients who were admitted to the Teaching Hospital Karapitiya (THK) from...
Cardiac arrest is a sudden loss of heart function with serious consequences. In developing countries, healthcare professionals use clinical documentation to track patient information. These data can be used to predict developing cardiac arrests. We are publishing the data set through open access to advance the research domain. Based on this data se...
Exposure to asbestos causes health hazards including asbestosis, mesothelioma and lung cancer. Asbestos industry workers are at a higher risk of exposure. Objective of this research is to assess the health status and the safety practices of asbestos industry workers. Four hundred seventy-five workers from three asbestos sheet manufacturing factorie...
Background: Core stability training (CST) is used to enhance sports performance. The relationship between core endurance and physical performance in rugby players had not been evaluated before in Asia.
Aims and Objectives: This study aims to determine the effects of a 6-week specific CST program on the core endurance and physical performances (spe...
Health Status and Safety Practices of Workers of Asbestos Sheet Manufacturing Factories in Sri Lanka.
Comparative evaluation of weight variation, hardness, friability, disintegration and dissolution parameters of commercially
available atorvastatin tablets marketed in Galle, Sri Lanka
Approximately 75% of global deaths from cardiovascular diseases occur in low and middle-income countries due to less access to essential cardiovascular medicines. Access to medicines is hindered by poor availability and unaffordable prices. The objective of this study was to assess the price, availability and affordability of cardiovascular medicin...
LUNG FUNCTIONS OF WORKERS OF ASBESTOS RELATED INDUSTRY IN SRI LANKA: A CASE-CONTROL STUDY
LUNG FUNCTIONS OF WORKERS OF ASBESTOS RELATED INDUSTRY IN SRI LANKA: A CASE-CONTROL STUDY
BACKGROUND
Abdominal pain-predominant functional gastrointestinal disorders (AP-FGIDs) are the most common cause of recurrent abdominal pain in children. Despite its high prevalence, the underlying pathophysiology of this condition is poorly understood.
AIM
To assess the role of gastric dysmotility and autonomic nervous system dysfunction in the p...
Professor K.N. Seneviratne Memorial Oration held by the Phsiological Society of Sri Lanka (PSSL). 30th K.N. Seneviratne memorial oration was held in 2017 which was delivered by Prof. Sampath Gunawardena on 24.11.2017 at the New Lecture Theater of the Faculty of Medicine, University of Colombo. The title of the oration was ’One Animal Model-Many Exp...
Objectives:
The aim of the study was to evaluate the therapeutic effect of domperidone on children with abdominal pain predominant functional gastrointestinal disorders (AP-FGIDs).
Methods:
One hundred children (aged 5-12 years) fulfilling Rome III criteria for AP-FGIDs were randomized into 8 weeks of domperidone or placebo treatment. Primary ou...
In Sri Lanka, four athletic deaths were reported in 2013. All four deaths took place while participating in school marathon competitions and the victims were teenaged school children. The Ministry of Health and Ministry of Education took steps to temporarily remove marathon events from school athletic competitions in 2014. Three more athletic death...
MAKING A LOW COST, IMPROVISED ELECTRONIC STETHOSCOPE
Sampath Gunawardena
Department of Physiology, Faculty of Medicine, University of Ruhuna
Introduction
There are different kinds of electronic stethoscopes available in the market with different capabilities. They are quite expensive with the price ranging from about 100 US Dollars to 500 US Dolla...
Anatomic variation and susceptibility for injuries depending on gender were described for the ulnar nerve. The aim of this study was to investigate the association between gender and ulnar never motor conductance and the influence of sidedness for this association. Study was conducted as a retrospective study using nerve conduction study data of ul...
As a peer-assisted learning process, minilectures on physiology were conducted by students. During this process, students lecture to their colleagues in the presence of faculty staff members. These lectures were evaluated by faculty staff and students simultaneously. The aim of this study was to compare feedback from faculty members and students on...
Decisions on diagnosis, management and prognosis often rest on the results of laboratory investigations. Therefore it is extremely important that we have medical laboratories which produce reliable investigation reports. In order to achieve this, we need to have medical laboratories which are credible and reliable. Sri Lanka Accreditation Board for...
Information technology (IT)-based components are included as active learning activities in medical curricula that have been shown to be more effective than most passive learning activities. In developing countries, these activities are not popular compared with developed countries. In this study, an IT-based assignment was carried out in physiology...
Feasibility of introducing information technology-based
activities into medical curricula in developing countries
Mahinda Kommalage & Sampath Gunawardena
Editor – Knowledge of information
technology (IT) among medical
undergraduates and health care
workers is higher in developed
countries1 than in developing
countries.2,3 In developing countries,
I...
Increasing the extravascular fluid of the airways acutely by obstructing pulmonary lymph drainage causes a reflex diuresis mediated by neuronal nitric oxide synthase in the renal medulla. The authors examined this reflex in rabbits with a chronic increase in extravascular fluid of the airways resulting from surgically induced mitral regurgitation....
• Unlike in normal rabbits, pulmonary rapidly adapting receptors (RARs) in rabbits with chronic mitral regurgitation (MR) do not respond to small changes in extravascular fluid (EVF) volume in major airways. The present study examined the effect of shrinking the EVF volume in rabbits with chronic MR by infusing hypertonic albumin, to see whether th...
The role of nitric oxide in the reflex diuresis in response to pulmonary lymphatic drainage was examined in anaesthetized, artificially ventilated New Zealand White rabbits. Pulmonary lymphatic drainage was obstructed by raising the pressure in a pouch created from the right external jugular vein. Pulmonary lymphatic obstruction resulted in a signi...
Effects of changes in extra-vascular fluid volume produced by pulmonary lymphatic obstruction and plasmapheresis on the activities of bronchial and pulmonary C fiber receptors and rapidly adapting receptors (RARs) were investigated in New Zealand White rabbits. In intact rabbits, pulmonary lymphatic obstruction either alone or in combination with p...
The mechanisms controlling the coronary vascular responses of vessels perfusing the left ventricular (LV) myocardium that is hypertrophied from chronic volume overload are unclear. We hypothesised that endothelial function is compromised, and receptor-mediated contraction is exacerbated, in coronary resistance vessels from rabbits with LV hypertrop...
The effects of acute pulmonary venous congestion on the activity of rapidly adapting receptors (RARs) were determined in intact (control and sham‐operated) rabbits and in rabbits 6 and 12 weeks after surgical destruction of the mitral valve.
Destruction of the mitral valve increased the mean left atrial pressure (LAP) by approximately 2·6 and 3·8 m...
A model of CMR was developed in rabbits by partial surgical damage of the valve cusps. Animals were maintained and allowed to develop chronic pulmonary venous congestion for 6 weeks(CMR6, n=8) and 12 weeks (CMR 12, n=13). Damage was confirmed by post-mortem examination of the mitral valve apparatus. Intact control (C, n=7) and sham operated (S, n=4...
