Sammy Florczak

• Master of Biofabrication, Master of Applied Science, Bachelor of Science (Physics)
• PhD Researcher at University Medical Center Utrecht

We introduce Generative, Adaptive, Context-Aware 3D Printing (GRACE), a novel approach combining 3D imaging, computer vision, and parametric modelling to create tailored, context-aware geometries using volumetric additive manufacturing. GRACE rapidly and automatically generates complex structures capable of conforming directly around features rangi...

Volumetric Bioprinting (VBP), enables to rapidly build complex, cell‐laden hydrogel constructs for tissue engineering and regenerative medicine. Light‐based tomographic manufacturing enables spatial‐selective polymerization of a bioresin, resulting in higher throughput and resolution than what is achieved using traditional techniques. However, meth...

Volumetric Bioprinting (VBP), enables to rapidly build complex, cell-laden hydrogel constructs for tissue engineering and regenerative medicine. Light-based tomographic manufacturing enables spatial-selective polymerization of a bioresin, resulting in higher throughput and resolution than what achieved using traditional techniques. However, methods...

Purpose In MR electrical properties tomography (MR‐EPT), electrical properties (EPs, conductivity and permittivity) are reconstructed from MR measurements. Phantom measurements are important to characterize the performance of MR‐EPT reconstruction methods, since they allow knowledge of reference EPs values. To assess reconstruction methods in a mor...

Herein we show an accessible technique based on Faraday waves that assist the rapid assembly of osteoinductive β-Tricalcium phosphate (β-TCP) particles as well as human osteoblast pre-assembled in spheroids. The hydrodynamic forces originating at 'seabed' of the assembly chamber can be used to tightly aggregate inorganic and biological entities at...

In living tissues, cells express their functions following complex signals from their surrounding microenvironment. Capturing both hierarchical architectures at the micro- and macroscale, and anisotropic cell patterning remains a major challenge in bioprinting, and a bottleneck towards creating physiologically-relevant models. Addressing this limit...

Major challenges in biofabrication revolve around capturing the complex, hierarchical composition of native tissues. However, individual 3D printing techniques have limited capacity to produce composite biomaterials with multi-scale resolution. Volumetric bioprinting recently emerged as a paradigm-shift in biofabrication. This ultra-fast, light-bas...

Herein we show an accessible technique based on Faraday waves that assist the rapid assembly osteoinductive β-TCP particles as well as human osteoblast pre-assembled in spheroids. The hydrodynamic forces originating at 'seabed' of the assembly chamber can be used to tightly aggregate inorganic and biological entities at packing densities that resem...

Conventional additive manufacturing and biofabrication techniques are unable to edit the chemicophysical properties of the printed object postprinting. Herein, a new approach is presented, leveraging light‐based volumetric printing as a tool to spatially pattern any biomolecule of interest in custom‐designed geometries even across large, centimeter...

In living tissues, cells express their functions following complex signals from their surrounding microenvironment. Capturing both hierarchical architectures at the micro- and macroscale, and anisotropic cell patterning remains a major challenge in bioprinting, and therefore a bottleneck towards creating physiologically relevant models. Addressing...

Major challenges in biofabrication revolve around capturing the complex, hierarchical composition of native tissues. However, individual 3D printing techniques have limited capacity to produce composite biomaterials with multi-scale resolution. Volumetric bioprinting recently emerged as a paradigm-shift in biofabrication. This ultra-fast, light-bas...

Bioprinting aims to produce 3D structures from which embedded cells can receive mechanical and chemical stimuli that influence their behavior, direct their organization and migration, and promote differentiation, in a similar way to what happens within the native extracellular matrix. However, limited spatial resolution has been a bottleneck for co...

Volumetric Bioprinting Volumetric bioprinting shapes organoid‐laden constructs into centimeter‐scale assemblies that mimic native liver function. In article number 2110054, Riccardo Levato and co‐workers report the development of a hydrogel‐based bioresin with tunable optical properties to minimize scattering in light‐based printing and ensure high...

Organ‐ and tissue‐level biological functions are intimately linked to microscale cell‐cell interactions and to the overarching tissue architecture. Together, biofabrication and organoid technologies offer the unique potential to engineer multi‐scale living constructs, with cellular microenvironments formed by stem cell self‐assembled structures emb...

Poly(vinylidene difluoride) (PVDF) has piezoelectric properties suitable for numerous applications such as flexible electronics, sensing and biomedical materials. In this study, individual fibers with diameters ranging from 17 to 55 µm were processed using melt electrowriting (MEW). Electroactive PVDF fibers can be fabricated via MEW, while the pol...

p>Poly(vinylidene difluoride) (PVDF) has piezoelectric properties suitable for numerous applications such as flexible electronics, sensing and biomedical materials. In this study, individual fibers with diameters ranging from 17-55 μm were processed using melt electrowriting (MEW). Electroactive PVDF fibers can be fabricated via MEW, while the poly...

It is broadly valued by the biomaterials community that electrospinning from both the solution and melt is a technologically attractive method to process polymeric and composite materials; yet the number of publications reported in the current scientific literature regards the two methods has an estimated ratio of 1 to 400. Among the many reasons f...