Samira Karim

World University of Bangladesh · Department of Pharmacy

Background Ficus nervosa (FN) leaves have been traditionally used in ethnomedicine for the treatment of various ailments, this study aimed to investigate the cold methanol extract of FN for its antioxidant, analgesic, antidiarrheal, and thrombolytic properties, along with preliminary phytochemical screening to identify key bioactive compounds and a...

The aim of the present study was to explore the existence of phytochemical constituents and presence of some potent pharmacological activity of Abroma augusta using standard method. Phytochemical analysis revealed the presence of phenol and flavonoid. Aqueous soluble fraction (AQSF) exhibited highest percentage (46.58%) of clot lysis activity compa...

World University of Bangladesh is a UGC and Government of Bangladesh approved university run by the Board of Trustees. Vice Chancellor, Pro-Vice Chancellor and Treasurer are appointed by the Chancellor who happens to be the President of People’s Republic of Bangladesh. The University has three faculties consisting of Departments namely Pharmacy, Me...

The in-vitro antimicrobial effectiveness of A. augusta was shown in (Table S4). Antimicrobic experiment was conducted on four gram positive and five-gram negative bacteria at a conc. of 400 μg/disc. DCMSF exhibited with highest zone of inhibition (19.60 ± 0.12 mm) in Bacillus subtilis, a gram-positive bacterium. Other organic soluble fractions such...

Ficus nervosa (F. nervosa) is a tree which crude methanolic extracts were partitioned successively using various solvents and subjected to determine qualitatively and quantitatively for the presence of different bioactive constitutes and fractions which were assessed for their possible pro-coagulant, antioxidant, astringent, antidiarrheal and analg...

To assure the quality of higher education for the sustainable development of the country. The survey was conducted by the assistance of HEQEP Project UGC and financed by World Bank. Quality of higher education is crucially important for the sustainable socioeconomic development of a nation particularly for developing countries like Bangladesh. The...

Aim:Crataeva nurvala (C. nurvala) is a medicinally active plant, potentially used as tradi-tional means of treating many health ailments such as prostatitis, prostate enlargement, inflammatory conditions, heart disease, thyroid and endocrine disorder, and urinary tract infection, respectively, in the rural region of Tangail, Jamalpur, Sherpur, and...

Eye is known as complicated and sophisticated organ to the body, so that especial attention need to give to the eye diseases. Different drug delivery system are available like rapid drainage, loss from tear flow, eye sensitivity due to protective anatomy and physiology of eye.Absorption and elimination of therapeutic active agents depend upon the p...

p>Present study aspires at the design of an immediate release formulation with prospective use of fexofenadine hydrochloride by exploring the effect of sodium starch glycolate as super disintegrant. Fexofenadine hydrochloride immediate release tablets (Formulations F-1, F-2, F-3, F-4 and F-5) using different ratios of sodium starch glycolate as a d...

Objective: To rationalize the folkloric use of hypoglycemic, antinociceptive and antioxidant potentials with phytochemical screening of methanolic bark extract of Crataeva nurvala (C. nurvala) in vivo and in vitro. Methods: The collected bark was dried and grinded. The coarse powder was soaked in 2 000 mL of 90% methanol for several days then filtr...

Objective The ethanolic plant extracts of Asparagus racemosus and their partitionates were assessed for thrombolytic, membrane stabilizing, antimicrobial and antioxidant activity in vitro . Methods The collected plant was dried and grinded. The coarse powder was shocked in 2000 mL of 90% methanol for several days then filtrated. At 40°C the volume...

Self-assessment report for institutional quality assurance program.

In this present study, the leaf extracts of Litsea liyuyingi, were subjected to evaluate the phytochemical screenings, thrombolytic, membrane stabilizing, antioxidant, antimicrobial, cytotoxic, anti-nociceptive, anti-diarrheal and hypoglycemic activity. In phytochemical screening the presence of flavonoids, saponins, alkaloids, phenols and tannins...

Plants parts and plant products of all the descriptions, particularly those with medicinal properties, are invariably used as principal components or ingredients of various traditional medicines. The ancient time of modern age the race successfully used plants and plant products as therapeutics tools for fitting against disease and various other he...

In this present study, the leaf extracts of Coccinia grandis L., were subjected to evaluation of the phytochemical screenings, thrombolytic, membrane stabilizing, antioxidant, antimicrobial and cytotoxic activity. The ethanol extract showed 43.71% clot lysis as compared to 65.16% clot lysis produced by standard streptokinase. In vitro membrane stab...

Objective: To justify the folkloric uses of Sesbania grandiflora (S. grandiflora) leaves, 90% ethanolic extract and their organic and aqueous partitioning substances were evaluated for their possible antioxidant, antidiarrhoeal and antimicrobial activity in vivo. Methods: Crude ethanolic extract of S. grandiflora leaves were being subjected to part...

Aim of the present study was to develop immediate release tablets of loratadine. Loratadine immediate release tablets were formulated by using different ratios of different superdisintegrants like sodium starch glycolate and kollidon CL with direct compression method. Tablets were prepared and evaluated for different quality parameters. A compariso...

This study was carried out to explore potential antibacterial, antioxidant, anti-inflammatory and thrombolytic effects of Catharantus roseus (Nayantara) by in-vitro methods and cytotoxic effect by in-vivo method. The methanol extracts of shoots showed potent antibacterial activity against various bacteria with zone of inhibition ranging from 10 mm-...

The ethanolic extract of leaves of Sesbania grandiflora and their organic and aqueous soluble partitioning substances were evaluated for thrombolytic and membrane stabilizing potentials in vitro. In thrombolytic assay, among all partitionates, the ethyl acetate soluble fraction showed highest percent of clot lysis (59.57%) as compared to 69.23% and...

p>The aim of this research was to develop and evaluate gastric floating tablets of salbutamol sulphate. The oral delivery of anti-asthmatic salbutamol sulphate tablets were facilitated by preparing floating dosage form which could increase its absorption in the stomach by increasing the gastric residence time of the drug. Floating tablets were form...

Objective: To justify the folkloric use of Swietenia mahagoni (S. mahagoni) seeds, 90% ethanolic extract and their aqueous and organic partitioning substances were evaluated for their possible antidiarrhoeal and antimicrobial potentials in vivo. Methods: Crude ethanolic extract of S. mahagoni seeds were subjected and partitioned into fractions usin...

Objective: To investigate the clot lysis, antimicrobic and membrane stabilizing potentials of ethanolic extractives of the leaves of Heliotropium indicum (H. indicum). Methods: Crude ethanolic extracts of H. indicum leaves were partitioned successively using solvents of different polarity and subjected to determine qualitatively and quantitatively...

The study aims at the design of a sustained release dosage form for potential use of aspirin which is currently used as the cardiotonic, analgesic, antipyretic and antiinflammatory agent to investigate the effect of polymers on the release pattern from tablets. Ethyl cellulose and hydroxypropyl methyl cellulose-K15 MCR polymers had been used in the...

This work aims at the design of a sustained release formulation of glimepiride which is currently available in the treatment of type 2 diabetes mellitus and to investigate the effect of polymers on the release profile of glimepiride. Glimepiride sustained release tablets were prepared by direct compression method using different ratios of various r...