Samerender N hMichigan Technological University | MTU · Department of Biomedical Engineering
Samerender N h
Doctor of Philosophy
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16
Publications
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Publications
Publications (16)
Here, we report a surfactant-free electrospinning based method for the synthesis of beaded manganese oxide (Mn2O3) nanofibers and their application as supercapacitor electrodes. The beaded morphology of the fibers was confirmed through electron microscopic analysis. The highly crystalline nature and lattice strain of the fibers were verified by X-r...
Inhibition of actin remodeling in nerves modulates action potential propagation and therefore could be used to treat acute pain. N-001 is a novel protein analgesic engineered from several C. Botulinum toxins. N-001 targets sensory neurons through ganglioside GT1b binding and ADP-ribosylates G-actin reducing actin remodeling. The activity and effica...
Electrospinning is a versatile tool used to produce highly customizable nonwoven nanofiber mats of various fiber diameters, pore sizes, and alignment. It is possible to create electrospun mats from synthetic polymers, biobased polymers, and combinations thereof. The post-processing of the end products can occur in many ways, such as cross-linking,...
Quantifying disorder in physical systems can provide unique opportunities to engineer-specific properties. Here, we apply a methodology based on the approach pioneered by Bragg and Williams for metal alloys to quantify the disorder characterizing polymer fibers including polyaniline (PANI), polyaniline-polycaprolactone (PANI-PCL), and polyvinyliden...
Overcoming the global concern of antibiotic resistance is one of the biggest challenge faced by scientists today and the key to tackle this issue of emerging infectious diseases is the development of next-generation antimicrobials. The rapid emergence of multi-drug resistant microbes, superbugs and mutated strains of viruses have fueled the search...
Tumorigenesis is a complex process involving numerous cellular signaling cascades and environmental factors. While 2D cultures for stiffness measurements and more recently 3D cultures to demonstrate differences in cell structures have been reported, very little is known about the impact of sugars in cell recruitment. In this study, we report the fa...
Goal: Artificially engineering the tumor microenvironment in vitro as a vital tool for understanding the mechanism of tumor progression. In this study, we developed three-dimensional cell scaffold systems with different topographical features and mechanical properties but similar surface chemistry. The cell behavior was modulated by the topography...
The mechanotransduction of cells is the intrinsic ability of cells to convert the mechanical signals provided by the surrounding matrix and other cells into biochemical signals that affect several distinct processes such as tumorigenesis, wound healing, and organ formation. The use of biomaterials as an artificial scaffold for cell attachment, diff...
In tissue engineering, the use of scaffolds helps establish a synergistic relationship between the scaffolds and the tissues by improving cell–scaffold interaction. This interaction is enhanced when physiologically relevant biophysical cues are replicated in the artificial scaffolds. Here, we present a novel scaffold that mimics the natural anisotr...
Electrospinning and polymer blending have been the focus of research and the industry for their versatility, scalability, and potential applications across many different fields. In tissue engineering, nanofiber scaffolds composed of natural fibers, synthetic fibers, or a mixture of both have been reported. This review reports recent advances in po...
The fabrication of synthetic scaffolds that mimic the microenvironment of cells is a crucial challenge in materials science. The honeycomb morphology is one such bio-mimicking structure that possesses unique physical properties and high packing efficiency in a 3-dimensional space. Here, we present a novel method for electrospinning polycaprolactone...
Electrospinning holds great promise for designing functional 3D biomimetic scaffolds for tissue engineering applications. The technique allows for the reproducible fabrication of 3D scaffolds with control over the porosity and thickness. In this work, a novel method for the synthesis of a 3D electroactive scaffold using electrospinning from polycap...
Synthesis of Novel Birnessite Type MnO2 Nanochains by Electrospinning
and their Application as Supercapacitor Electrodes MUHAMED
SHAREEF, Kansas State University, MILAN PALEI, SAMERENDER HANUMANTHA
RAO, TIRUPATTUR NATARAJAN, Indian Institute of Technology
Madras, GURPREET SINGH, Kansas State University — A first time method
for the synthesis of con...
This abstract proposes a novel approach to prevent accidents when the driver becomes unconscious or if he is in an intoxicated state. An integrated system of sensors and alarms are designed for the same. Using a high-resolution eye camera, pupil dilation is detected and tested against a pre-determined set of data value to confirm the persons mental...
Questions
Questions (2)
I want to prepare conductive polyaniline nanofibers from emeraldine salt (procurred from sigma aldrich) by electrospinning for tissue engineering applications. I recently read from the work by Dr. Bernhard Wessling that only dispersions could be created of conductive polymers like PANi. The solvents suggested so far are either carcinogenic or highly viscous (eg.DMSO). Can you please suggest me other chemicals or polymers which I could use to obtain stable dispersions which can be used for electrospinning?
I'm electrospinning PANI/PVDF fibers for neural tissue engineering. I have tried different ratios of PVDF and PANi but the beading occurs. Does this mean that I need to use another polymer along with this?
