Sameh Abouzid

Sameh Abouzid
Heliopolis University · Department of Pharmacognosy

About

23
Publications
9,193
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
370
Citations

Publications

Publications (23)
Article
Full-text available
Hepatocellular carcinoma (HCC) has been identified as one of the most deadly malignancies with limited therapeutic efficacy worldwide. However, understanding the molecular mechanisms of crosstalk between signaling pathways in HCC and predicting cancer cell responses to targeted therapeutic interventions remain to be challenge. Thus, in this study,...
Article
Full-text available
The present work was designed to assess the efficacy of Silybum marianum total extract (STE), silymarin (Sm), and silibinin (Sb) against experimentally induced renal carcinogenesis in male Wistar rats and their roles in regulating oxidative stress, inflammation, apoptosis, and carcinogenesis. The diethylnitrosamine (DEN)/2-acetylaminofluorene (AAF)...
Article
Fumaria parviflora Lam. is a rare herbaceous annual plant, with a well-known richness of isoquinoline alkaloids. It is threaten due to expansion on construction in the Mediterranean coastal region. We established callus culture protocol aiming at in vitro conservation of this plant. Murashige and Skoog medium fortified with a combination of 0.5 mg/...
Article
Full-text available
Legume sprouts are a fresh nutritive source of phytochemicals of increasing attention worldwide owing to their many health benefits. Nuclear magnetic resonance (NMR) was utilized for the metabolite fingerprinting of 4 major legume sprouts, belonging to family Fabaceae, to be exploited for quality control purposes. Thirty-two metabolites were identi...
Article
Full-text available
Silybum marianum (L.) Gaertn. (Asteraceae) was hydroponically cultured using a nutrient film technique system. Silibinin, isosilibinin and silychristin were detected in the fruits of the cultured plants. The effect of salicylic acid on the improvement of flavonolignans production by the fruits of the hydroponically cultured S. marianum was investig...
Article
Quantitative correlations between the contents of the flavonolignans silychristin A and silybins A/B provide biosynthetic clues that support a pathway in which one mesomeric form of a taxifolin radical is undergoing an oxidative coupling with a coniferyl alcohol radical. The flavonolignan content and patterns reported in the literature for 53 sampl...
Article
Silymarin prepared from the fruits of Silybum marianum (L.) Gaertn. (Asteraceae) has long been used for the treatment of liver disorders. This study was carried out to evaluate the protective effect of the fruit extract of white-flowered S. marianum variety albiflorum Eig. (WSE) against paracetamol–induced liver toxicity in rats. Silyhermin, isosil...
Article
Full-text available
This study is designed to assess the preventive effects Punica granatum aril juice, aqueous extracts of seeds and husk and their mixture on the hepatic injury and hepatocarcinogenesis induced by 7,12-dimethylbenz(a)anthracene (DMBA) and carbon tetrachloride (CCl4) administration in male Wistar rats. DMBA/CCl4-administered rats were orally treated w...
Article
Full-text available
This study is designed to assess the preventive effects Punica granatum aril juice, aqueous extracts of seeds and husk and their mixture on the hepatic injury and hepatocarcinogenesis induced by 7,12-dimethylbenz(a)anthracene (DMBA) and carbon tetrachloride (CCl4) administration in male Wistar rats. DMBA/CCl4-administered rats were orally treated w...
Article
This study is designed to assess the preventive effects Punica granatum aril juice, aqueous extracts of seeds and husk and their mixture on the hepatic injury and hepatocarcinogenesis induced by 7,12-dimethylbenz(a)anthracene (DMBA) and carbon tetrachloride (CCl 4) administration in male Wistar rats. DMBA/CCl 4-administered rats were orally treated...
Article
Full-text available
Background: Both 7,12-dimethylbenz (a) anthracene and carbon tetrachloride are xenobiotics that are implicated in various toxicological effects including carcinogenesis. Punica granatum constituents have antioxidant and anti-inflammatory activities. This study is conducted to assess the preventive effects of pomegranate (Punica granatum) juice, see...
Article
Full-text available
Balady and Chinese-Sids40 are the main garlic cultivars grown in Egypt. Effect of conventional vs. organic agricultural practices on premature and mature garlic bulb yield was studied for these cultivars. Organic agriculture increased yield of garlic bulbs and was more effective in Balady than in Chinese-Sids40 cultivar. Effect of cultivar type, ma...
Article
Full-text available
Abstract Diabetes mellitus is a major global health problem. Various plant extracts have proven antidiabetic activity and are considered as promising substitution for antidiabetic drugs. The antihyperglycemic effect of 16 plants and 4 algae, commonly used in Egypt for the treatment of diabetes mellitus, was investigated. A diabetes model was induce...
Article
Tamarix nilotica (Ehrenb.) Bunge (Tamaricaceae) has been used since Pharaonic times to expel fever, relieve headache, draw out inflammation and as an aphrodisiac agent. In vitro antioxidant activity of extracts prepared from the leaves and flowers of T. nilotica was tested. Three in vitro antioxidant assays were used: 1,1-diphenyl-2-picryl hydrazyl...
Article
Full-text available
BACKGROUND & OBJECTIVE: Worldwide, the incidence of type-2 diabetes is rising rapidly, mainly because of the increase in the incidence of obesity, which is an imporant risk factor for this condition. Both obesity and type-2 diabetes are complex genetic traits but they also share some nongenetic risk factors. Differences among individuals in their s...
Article
Background: Dalbergia paniculata Roxb. (Fabaceae) is a tree that is widely distributed throughout Sourthern and Central India. It is known to possess antimicrobial, antioxidant, anti-inflammatory and antidiarrhoeal activities. No scientific evidence is available for the biological effects of this plant. This study aimed to isolate the isoflavonoids...
Article
Ashwaghanda, Withania somnifera , is one of the most widely used herbs in Ayurvedic medicine. Leaves and roots are the traditionally used parts of the plant. An RP-HPLC method using a binary acetonitrile-water gradient containing 0.1% acetic acid has been developed for analysis of withaferin A. The method was validated in accordance with ICH guidel...
Article
Full-text available
Root cultures of Withania coagulans (Solanaceae) were obtained from in vitro germinated sterileplantlets. The roots grew axenically in MS medium containing 0.25 mgL-1 indole-3-butyric acid and 30 gL-1sucrose. A RP-HPLC method for the determination of withanolides in plant tissues was developed using abinary gradient solvent system comprising aceton...
Article
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Article
Full-text available
Phytochemical investigation of the leaves of Tamarix nilotica (Tamaricaceae) has led to isolation of methyl ferulate 3-O-sulphate (1) for the first time from natural sources. In addition, coniferyl alcohol 4-O-sulphate (2), kaempferol 4'-methyl ether (3), tamarixetin (4) and quercetin 3-O-beta-D-glucupyranuronide (5) were isolated from the n-butano...
Article
Antioxidant activity of a selection of commonly occurring wild plants growing in Beni-Sueif governorate, Upper Egypt, has been tested. The plants selected are Tamarix nilotica, Ambrosia maritima, Zygophyllum coccenium, Conyza dioscoridis, Chenopodium ambrosioides, and Calotropis procera. The in vitro antioxidant assays used in this study were 1,1-d...

Network

Cited By