Sameera D. Viswakula

Sameera D. Viswakula
University of Colombo · Department of Statistics

PhD (Genomic Biostatistics), MS (Statistics), BSc (Statistics special)

About

16
Publications
3,124
Reads
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60
Citations
Citations since 2017
12 Research Items
56 Citations
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Introduction
Strong background in probabilistic/statistical modeling and statistical computing using R, and C++. Hands on experience in handling NGS data using C++, Perl and Python languages, sequencing using Bowtie and manipulating using SRA/SAM Tools on Linux high performance computing clusters. Experience in developing new statistical frameworks to identify DNA – protein binding sites in ChIP-Seq data on UCSC Genome Browser and NCBI databases.
Additional affiliations
August 2011 - May 2015
Old Dominion University
Position
  • PhD

Publications

Publications (16)
Preprint
Full-text available
Background Dengue haemorrhagic fever (DHF) causes significant morbidity and mortality. Judicious fluid resuscitation is the cornerstone of managing vascular leakage in DHF and haematocrit (HCT) measurement is used to monitor the response to fluid resuscitation. Serum lactate level is a measure of tissue perfusion which can be a useful parameter to...
Presentation
Full-text available
Equity research is among the most important information sources for making investment decisions on equities. The purpose of this study is to utilize statistical measures to evaluate the estimates and recommendations forecasted in equity research reports. Measures are applied to a publicly sourced data set of 16699 forecasts by 27 brokerages coverin...
Article
Full-text available
Dengue is one of the most important vector-borne infection in Sri Lanka currently leading to vast economic and social burden. Neither a vaccine nor drug is still not being practiced, vector controlling is the best approach to control disease transmission in the country. Therefore, early warning systems are imminent requirement. The aim of the study...
Article
Full-text available
Dengue is the most important mosquito-borne viral infection disease in Sri Lanka triggering extensive economic and social burden in the country. Even after numerous source reduction programmes, more than 30,000 incidences are reporting in the country every year. The last and greatest dengue epidemic in the country was reported in July, 2017 with mo...
Article
Full-text available
Dengue is the most important mosquito-borne viral infection in Sri Lanka causing an enormous social and economic burden in the country. In the absence of therapeutic drugs and the developed vaccines are under investigation, vector control is the best strategy to reduce the disease transmission. Therefore, the development of novel tools to control d...
Article
Full-text available
Background: Breast cancer (BC) is known to be the most common malignancy in females whereas colorectal cancer (CRC) incidence also higher in both genders in Sri Lanka. TP53 is an important tumour suppressor gene and its somatic mutations are reported in approximately 27% of BC and 43% of CRC cases. Analysis of TP53 gene variants not only provides...
Conference Paper
A Scientific method of selecting all possible fraudulent combinations from the weekly pre-auction, where tea samples are bided by the tea exporting companies to be purchased for exporting purposes is critical to mitigate frauds in tea exports from Sri Lanka. Therefore, building a proper mechanism to predict fraudulent samples received by the tea ta...
Article
Full-text available
Background: Dengue is one of the major health problems in Sri Lanka causing an enormous social and economic burden to the country. An accurate early warning system can enhance the efficiency of preventive measures. The aim of the study was to develop and validate a simple accurate forecasting model for the District of Gampaha, Sri Lanka. Three tim...
Article
Full-text available
Abstract Leptospirosis is a zoonostic infectious disease, caused by a pathogenic species of the Genus Leptospira. In recent years, a markedly increased number of leptospirosis cases have been reported in the District of Gampaha, in the Western Province of Sri Lanka. Typically, the risk of the disease in the district is seasonal with a small spike o...
Article
Full-text available
We sought to evaluate the success of prehospital, non-drug assisted endotracheal intubation performed by Virginia prehospital care providers and to develop a model designed to predict the probability of success of endotracheal intubation.Methods We conducted a retrospective observational study on prehospital, non-drug assisted endotracheal intubati...
Article
The tremendous demand on computer memory and computing time for prediction of complex secondary structures limits the applicability of most RNA secondary structure prediction programs available to short RNA sequences. We propose to approach this problem by segmenting a long RNA sequence into shorter non-overlapping chunks, predicting the secondary...
Article
Full-text available
Conditional logistic regression models have been extensively used in the field of medicine and mainly applied in matched case control studies. However, none of the major statistical packages, i.e. SAS, MINITAB, SPSS provide diagnostics to assess the goodness-of-fit of these models. In addition the freely downloadable package R provides no functions...

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Projects

Projects (3)
Project
In this project we aimed at developing new data mining algorithms combing Statistical & AI techniques with mathematical optimization. These algorithms will overcome the problems due to non-Gaussianity and non-stationarity of spatio-temporal data.
Project
To model dengue incidents in Sri lanka.