Samantha Treagus- Doctor of Philosophy
- Senior Research Scientist at UK Health Security Agency
Samantha Treagus
- Doctor of Philosophy
- Senior Research Scientist at UK Health Security Agency
Development of high throughput metagenomic pipelines for sequencing of human pathogens from clinical samples.
About
7
Publications
1,200
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115
Citations
Introduction
My research interests revolve around viruses posing significant health risks to the public, and how wastewater and sequencing techniques can be used to monitor the burden and transmission of viruses in the community.
Current institution
UK Health Security Agency
Current position
- Senior Research Scientist
Additional affiliations
September 2017 - September 2021
October 2017 - September 2021
Position
- PhD Student
Description
- Collaborative PhD student with the University of Exeter, working at Cefas to detect human viruses within the aquatic environment, such as hepatitis E virus, hepatitis a virus, norovirus and sapovirus, and analyse their sources.
Education
September 2017 - May 2022
University of Exeter
Field of study
- Virology
September 2013 - July 2017
Publications
Publications (7)
Contamination of bivalve shellfish, particularly oysters, with norovirus is recognised as a significant food safety risk. Methods for quantification of norovirus in oysters using the quantitative real-time reverse transcription polymerase chain reaction (RT-qPCR) are well established, and various studies using RT-qPCR have detected norovirus in a c...
Globally, Hepatitis E virus (HEV) causes over 20 million cases worldwide. HEV is an emerging and endemic pathogen within economically developed countries, chiefly resulting from infections with genotype 3 (G3) HEV. G3 HEV is known to be a zoonotic pathogen, with a broad host range. The primary source of HEV within more economically developed countr...
Norovirus is one of the largest causes of gastroenteritis worldwide, and Hepatitis E virus (HEV) is an emerging pathogen that has become the most dominant cause of acute viral hepatitis in recent years. The presence of norovirus and HEV has been reported within wastewater in many countries previously. Here we used amplicon deep sequencing (metabarc...
Noroviruses (NoVs) are the leading cause of non-bacterial gastroenteritis with societal costs of US$60.3 billion per annum. Development of a long amplicon nanopore-based method for dual-typing the RNA-dependent RNA polymerase (RdRp) and major structural protein (VP1) regions from a single RNA fragment could improve existing norovirus typing methods...
Noroviruses (NoV) are the leading cause of non-bacterial gastroenteritis across the globe with societal costs of US$60.3 billion per annum. Development of a long amplicon nanopore-based method for dual-typing the RNA-dependent RNA polymerase (RdRp) and major structural protein (VP1) regions from a single RNA fragment could improve existing noroviru...
Rift Valley fever virus (RVFV) is a mosquito-borne zoonotic pathogen causing disease in livestock and humans. Whilst initially restricted to the African continent, recent spread to the Arabian Peninsula has highlighted the likelihood of entry into new regions. Due to the absence of a regulatory-approved human vaccine, work is ongoing to develop and...
New vaccines, therapeutics and immunity elicited by natural infection create evolutionary pressure on SARS-CoV-2 to evolve and adapt to evade vaccine-induced and infection-elicited immunity. Vaccine and therapeutics developers thus find themselves in an “arms race” with the virus. The ongoing assessment of emerging SARS-CoV-2 variants remains essen...
