Salvador Rassi

Salvador Rassi
Universidade Federal de Goiás | UFG · Departamento de Clínica Médica

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52
Publications
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Publications

Publications (52)
Article
Introduction: Pulmonary hypertension (PH), a serious clinical condition, can lead to right ventricular systolic dysfunction (RVSD) with prognostic implications. Patients with suspected PH should undergo transthoracic echocardiography (TTE) for diagnosis and evaluation as the main screening and follow-up exam. Objective: To verify the associations o...
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Importance There is limited evidence on the benefits of sacubitril/valsartan vs broader renin angiotensin system inhibitor background therapy on surrogate outcome markers, 6-minute walk distance, and quality of life in patients with heart failure and mildly reduced or preserved left ventricular ejection fraction (LVEF >40%). Objective To evaluate...
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Purpose: This study aims to define which of the right ventricular myocardial deformation indices best correlates with the classic echocardiographic measurements and indices of right ventricular (RV) dysfunction in patients with stable chronic obstructive pulmonary disease (COPD). Patients and methods: Ninety-one patients with stable COPD underwe...
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The latest Heart Failure Guidelines by the Department of Heart Failure of the Brazilian Society of Cardiology (DEIC/SBC) were finalized on March 2018. Since then, a significant number of therapeutic interventions and diagnostic approaches has arisen or consolidated their position in international clinical practice and in clinical research. In addit...
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Background The physical examination enables prognostic evaluation of patients with decompensated heart failure (HF), but lacks reliability and relies on the professional’s clinical experience. Considering hemodynamic responses to “fight or flight” situations, such as the moment of admission to the emergency room, we proposed the calculation of the...
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Background: Dobutamine stress echocardiography (DSE) is an important tool in the diagnosis of coronary artery disease. However, there is hesitation in clinical practice for using it in patients with Chagas disease (CD) due to the arrhythmogenic potential of this heart condition. This study aimed to evaluate the incidence and variables associated w...
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Aims: The SHIFT trial showed that ivabradine reduced heart rate (HR) and the risk of cardiovascular outcomes. Concerns remain over the efficacy and safety of ivabradine on heart failure (HF) due to Chagas disease (ChD). We therefore conducted a post hoc analysis of the SHIFT trial to investigate the effect of ivabradine in these patients. Methods...
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Background A few decades ago, patients with Chagas disease were predominantly rural workers, with a low risk profile for obstructive coronary artery disease (CAD). As urbanization has increased, they became exposed to the same risk factors for CAD of uninfected individuals. Dobutamine stress echocardiography (DSE) has proven to be an important tool...
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Background: Acute myocardial infarction is a common condition among developing countries with access-tocare issues. However, scarce information is available on the association between prognostic markers and patient outcomes in areas around the globe with scarcere sources. Aim: To evaluate the association between creatine phosphokinase myocardial ba...
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Background: Treatment with stem cells in several cardiomyopathies may be related to the increase in arrhythmias. Objectives: To determine whether intracoronary injection of stem cells in patients with Chagas cardiomyopathy is associated with increased incidence of ventricular arrhythmias, compared to the Control Group. Methods: A retrospective co...
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Right ventricular pacing may be deleterious in patients with left ventricular dysfunction, but in patients with normal function the impact of this stimulation triggering clinically relevant ventricular dysfunction is not fully established. To evaluate the clinical, echocardiographic findings of patients with previously normal left ventricular funct...
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Background: Anemia in heart failure patients and has been associated with increased morbi-mortality. Previous studies have treated anemia in heart failure patients with either erythropoietin alone or combination of erythropoietin and intravenous (i.v.) iron. However, the effect of i.v. or oral (p.o.) iron supplementation alone in heart failure pat...
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BACKGROUND: Several local registries have sought to individually depict clinical characteristics of patients hospitalized with heart failure (HF) in Brazilian hospitals and communities. Overall, the analysis of these data suggests that there are important differences in etiology, decompensation factors, treatment and prognosis of patients with HF i...
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Background: Heart failure (HF) is a complex syndrome characterized by intolerance to exertion and reduced functional capacity. Objective: To assess the functional capacity of patients with HF and supplemented with creatine. Methods: Prospective, randomized, double-blind study. Thirty-three male patients over the age of 18 years with functional...
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Previous studies suggested that transplantation of autologous bone marrow-derived mononuclear cells (BMNCs) improves heart function in chronic chagasic cardiomyopathy. We report the results of the first randomized trial of BMNC therapy in chronic chagasic cardiomyopathy. Patients 18 to 75 years of age with chronic chagasic cardiomyopathy, New York...
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BACKGROUND: Concomitant asymptomatic coronary artery disease in patients with Chagas cardiomyopathy in heart failure is controversial in the medical literature, as both diseases are prevalent in some regions of Brazil.OBJETIVE: To determine the prevalence of coronary artery disease (lesions > 50%) in a specific population of patients with Chagas ca...
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Concomitant asymptomatic coronary artery disease in patients with Chagas cardiomyopathy in heart failure is controversial in the medical literature, as both diseases are prevalent in some regions of Brazil. To determine the prevalence of coronary artery disease (lesions > 50%) in a specific population of patients with Chagas cardiomyopathy in HF fu...
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Heart failure is a complex syndrome with multiple risk factors involved in its genesis, making its prevention and management difficult to achieve. To identify the main etiologies and risk factors in heart failure; to compare clinical and demographic characteristics of patients according to the etiology; analyze whether the treatment is according to...
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The stimulation of the right ventricle (RV) may be deleterious in patients with ventricular dysfunction; however there is little evidence about the impact of this stimulation in patients with normal ventricular function. To assess the clinical and laboratory evolution of patients with normal ventricular function submitted to implant of artificial c...
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FUNDAMENTO: Os fatores de risco para as síndromes hipertensivas gestacionais (SHG) são vários e podem relacionar-se à região e etnia da população. No Estado de Goiás, são escassos os estudos sobre esse tema. OBJETIVO: Investigar os fatores de risco maternos para SHG. MÉTODOS: Utilizou-se um estudo caso-controle por meio da análise dos prontuários d...
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There are several risk factors for hypertensive syndromes in pregnancy (HSP), and these can be related to regional and ethnic factors. Studies on this issue are scarce in the State of Goiás. To investigate maternal risk factors for HSP. Case-control study based on the analysis of medical records of parturients from the Maternity Service of Hospital...
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FUNDAMENTO: A levosimendana é um novo agente inodilatador que aumenta a contratilidade cardíaca pela sensibilização ao Ca(2+) e induz vasodilatação por meio da ativação dos canais KATP/BKCa. OBJETIVO: Estudar a eficácia e segurança da levosimendana em uma coorte brasileira portadora de insuficiência cardíaca descompensada e em pacientes resistentes...
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Levosimendan is a new inodilatory agent that enhances cardiac contractility via Ca(2+) sensitization and induces vasodilation through the activation of KATP/BKCa. To study the efficacy and safety of levosimendan in a decompensated heart failure (DHF) Brazilian cohort, and in b-adrenergic agonist resistant patients. The Brazilian Evaluation of Levos...
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Anemia is a common finding in heart failure (HF) patients and has been associated with increased morbidity and mortality. It is generally denominated as anemia of chronic disease (ACD), but the association with true ferropenic anemia is common. Many studies have investigated the effects of treating anemia in HF patients with either erythropoietin a...
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To study survival and prognostic factors associated with mortality in patients with systolic heart failure followed up since symptom onset. We carried out a study with a cohort of 204 consecutive patients with systolic heart failure, whose symptom onset occurred within the 6 weeks preceding the first medical visit. They were followed up for 46 mont...
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OBJETIVO: Analisar a sobrevida e fatores prognósticos associados à mortalidade em pacientes com insuficiência cardíaca sistólica acompanhados desde o início de seus sintomas. MÉTODOS: Coorte de 204 pacientes consecutivos com insuficiência cardíaca sistólica, identificada com início dos sintomas até seis semanas do primeiro atendimento e seguida por...
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Optional statement At least 30% of patients with congestive heart failure have preserved systolic function in the absence of significant valvular heart disease. These patients have diastolic dysfunction. Patients are frequently older and hypertensive. The rate of hospitalization in these patients is similar to that in patients with systolic dysfunc...
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numa populacao de idosos foi feita por Topol e cols., em 1985.As evidencias cientificas sobre o impacto do tratamento medica-mentoso da insuficiencia cardiaca com funcao sistolica preserva-da sobre a qualidade de vida, alivio sintomatico ou mortalidadesao escassas e, no momento atual, seis ensaios clinicos multi-centricos estao em curso, avaliando...
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1. INTRODUÇÃO A doença arterial coronariana é a causa mais comum de insuficiência cardíaca no mundo ociden-tal, sendo responsável por aproximadamente 60% destes pacientes [1] . Os benefícios da cirurgia de revascularização miocárdica em pacientes com angina ou com evidencias de isquemia induzida por exercício estão bem definidos. Entretanto, o pape...

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