Salles Sebastien

Sorbonne Université | UPMC · Laboratoire d'Imagerie Biomédicale (LIB)

Background Evaluation of cardiac function is crucial for management of patients with acute myocardial infarction (AMI). Recently, high frame rate (HFR) echocardiography has enabled identification of fast-propagating mechanical waves (MW) within the myocardium. These waves have the potential to offer unique insights into myocardial tissue properties...

Introduction Numerous studies have shown that natural mechanical waves have the potential to assess the elastic properties of the myocardium. When the Aortic and Mitral valves close, a shear wave is produced, which provides insights into tissue stiffness. In addition, the Atrial Kick (AK) generates a wave similar to Pulse Waves (PWs) in arteries, p...

Abstract Background Mechanical wave velocity (MWV) measurement is a promising method for evaluating myocardial stiffness, because these velocities are higher in patients with myocardial disease. Objectives Using high frame rate echocardiography and a novel method for detection of myocardial mechanical waves, this study aimed to estimate the MWVs f...

Improving the image quality of 3D high-frame-rate (HFR) echocardiography has become an important research focus. Diverging Waves techniques have already shown promising results in 3D ultrasound imaging. However, phase delays induced by large tissue displacements between ultrasound transmission can deteriorate the compounding process. Motion compens...

The mechanical wave (MW) propagation velocity in the heart is related to the tissue stiffness and its measurement mainly relies on manual evaluation of the 1D wave projection. This study presents an automated method for 3D wave visualization and velocity estimation in the heart using 3D ultrasound imaging of the left ventricle (LV). High-quality (H...

Ultrafast ultrasound imaging remains an active area of interest in the ultrasound community due to its ultra-high frame rates. Recently, a wide variety of studies based on deep learning have sought to improve ultrafast ultrasound imaging. Most of these approaches have been performed on radio frequency (RF) signals. However, in-phase/quadrature (I/Q...

In this chapter, we first review the reasons why conventional ultrasonography fails to image the interior of bones. Next we show our recent work on imaging a cortical bone layer with ultrasound. Revealing the shape of the cortex of a bone, in particular its thickness, is of interest for evaluating bone strength. In addition we describe how the proc...

Intraosseous blood circulation is thought to have a critical role in bone growth and remodeling, fracture healing, and bone disorders. However, it is rarely considered in clinical practice due to the absence of a suitable non‐invasive in vivo measurement technique. In this work, we assessed blood perfusion in tibial cortical bone simultaneously wit...

Intraosseous blood circulation is thought to have a critical role in bone growth and remodeling, fracture healing, and bone disorders. However, it is rarely considered in clinical practice due to the absence of a suitable non-invasive in vivo measurement technique. In this work, we assessed blood perfusion in tibial cortical bone simultaneously wit...

A wide variety of studies based on deep learning have recently been investigated to improve ultrasound (US) imaging. Most of these approaches were performed on radio frequency (RF) signals. However, inphase/quadrature (I/Q) digital beamformers (IQBF) are now widely used as low-cost strategies. In this work, we leveraged complex convolutional neural...

Objectives This study aimed to investigate the potential of a novel 3-dimensional (3D) mechanical wave velocity mapping technique, based on the natural mechanical waves produced by the heart itself, to approach a noninvasive 3D stiffness mapping of the left ventricle. Background Myocardial fibrosis is recognized as a pathophysiological substrate o...

In the feasibility study described here, we developed and tested a novel method for mechanical wave velocity estimation for tissue fibrosis detection in the myocardium. High-frame-rate ultrasound imaging and a novel signal processing method called clutter filter wave imaging was used. A mechanical wave propagating through the left ventricle shortly...

In recent years, diverging wave (DW) ultrasound imaging has become a very promising methodology for cardiovascular imaging due to its high temporal resolution. However, if they are limited in number, DW transmits provide lower image quality compared with classical focused schemes. A conventional reconstruction approach consists in summing series of...

In recent years, diverging-wave (DW) ultrasound imaging has become a very promising methodology for cardiovascular imaging due to its high temporal resolution. However, if they are limited in number, DW transmits provide lower image quality compared with classical focused schemes. A conventional reconstruction approach consists in summing series of...

The elastic properties of human tissue can be evaluated through the study of mechanical wave propagation captured using high-frame rate ultrasound imaging. Methods such as block-matching or phase-based motion estimation have been used to estimate the displacement induced by the mechanical waves. In this paper, a new method for detecting mechanical...

We have investigated the feasibility of noninvasive mapping of mechanical activation patterns in the left ventricular (LV) myocardium using high frame rate ultrasound imaging for the purpose of detecting conduction abnormalities. Five anesthetized, open-chest dogs with implanted combined sonomicrometry and electromyography (EMG) crystals were studi...

Demonstration videos.

In this study, a new spatial and temporal FIR clutter filter has been developed using the tissue velocity. This filter uses the PSF attenuation and the tissue velocity estimates to design a filter which is time-dependent but also a function of the position relative to the tissue. The spatial and temporal adaptive FIR filter is compared with three s...

Goal: This paper describes a method to enhance, visualize and reveal subtle motion that can be present in medical images. As proposed in vision applications, the principle is to magnify displacement applied, in this case, to cardiovascular tissues (carotid). Methods: In the example presented, ultrasound data were acquired at a high frame rate an...

Early detection of cardiovascular diseases can be done by assessing the dynamic properties of arteries. In this study, two phenomena related to the carotid wall motion are presented. The 2D motion estimation method employs (i) ultrafast imaging which became a world-wide use modality, (ii) transverse oscillations technics which allow improving the m...

Recent studies showed the potential of the Phase Based Motion Estimator when applied to ultrasound images containing transverse oscillations. Even though the emergence of ultrafast or high frame rates imaging overcame some of the prior limitations of the algorithm regarding its capability to detect large displacement values, the method still presen...

High frame rate imaging became a world-wide use modality. It achieves by coherently coalescing the received radio frequency signal, as low-resolution image, after emitting plane waves. One common way to increase the image quality is to combine multiple low-resolution images, from different insonification angles, into a high-resolution image. Howeve...

We present a new method to estimate 4-D (3-D + time) tissue motion. The method used combines 3-D phase based motion estimation with an unconventional beamforming strategy. The beamforming technique allows us to obtain full 3-D RF volumes with axial, lateral, and elevation modulations. Based on these images, we propose a method to estimate 3-D motio...

Ultrafast ultrasound is a promising imaging modality that enabled, inter alia, the development of pulse wave imaging and the local velocity estimation of the so-called pulse wave for a quantitative evaluation of arterial stiffness. However, this technique only focuses on the propagation of the axial displacement of the artery wall, and most techniq...

Purpose: Tracking the motion of biological tissues represents an important issue in the field of medical ultrasound imaging. However, the longitudinal component of the motion (i.e. perpendicular to the beam axis) remains more challenging to extract due to the rather coarse resolution cell of ultrasound scanners along this direction. The aim of this...

Quantitative ultrasound (QUS) based on backscatter coefficient (BSC) estimation has shown potential for tissue characterization. Beamforming using plane wave compounding has advantages for echographic, Doppler, and elastographic imaging; however, to date, plane wave compounding has not been experimentally evaluated for the purpose of BSC estimation...

This paper presents an experimental study of two dimensional (2D) tissue motion estimation in ultrafast imaging using transverse oscillation and a phase based motion estimation. In this study, the motion is measured all along the wall of an artery phantom. The method employs ultrafast imaging which has become a world-wide used modality, with severa...

In this paper, we propose the combination of fast plane wave imaging and transverse oscillation techniques (TO) in medical ultrasound for 2D vector motion estimation. Although transverse oscillation imaging has been originally developed as a mean to estimate blood vector flow, it has also been used for tissue motion in elastography or echocardiogra...

By contrast with 2D imaging, quantitative analysis of 3D motion from ultrasound images can provide improved information in several applications, such as arterial mechanical assessment, heart motion and blood flow. Unfortunately, it remains difficult to obtain a high definition of the motion estimate in the lateral and elevation directions (i.e. per...

Early detection of cardiovascular diseases (CVD) is possible by assessing the dynamic properties of the common carotid artery, i.e. the 2D (radial and longitudinal) motion of the wall layers. B-mode imaging is widely used, however this modality does not provide a high definition in the longitudinal direction (i.e. parallel to the probe) due to the...