Sallam Alagawani- PhD Candidate at Swinburne University of Technology
Sallam Alagawani
- PhD Candidate at Swinburne University of Technology
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Publications (3)
The epidermal growth factor receptor (EGFR) is a pivotal target in cancer therapy due to its significance within the tyrosine kinase family. EGFR inhibitors like AG-1478 and PD153035, featuring a 4-anilinoquinazoline moiety, have garnered global attention for their potent therapeutic activities. While pre-clinical studies have highlighted the signi...
Optical spectroscopy (UV-vis and fluorescence spectroscopy) is sensitive to the chemical environment and conformation of fluorophores and therefore, serves as an ideal probe for the conformation and solvent responses. Tyrosine kinase inhibitors (TKI) such as AG-1478 of epidermal growth factor receptor (EGFR) when containing a quinazolinamine scaffo...
Optical spectra (UV-vis and fluorescence) are sensitive to the chemical environment and conformation of fluorophores and therefore, are ideal probes for their conformation and solvent responses. Tyrosine kinase inhibitors (TKI) such as AG-1478 of epidermal growth factor receptor (EGFR) when containing a quinazolinamine scaffold are fluorophores. Co...
