Salah Dine Qanadli

• Professor MD MSc PhD FCIRSE FPAIRS
• Professor at Lausanne University Hospital

Objectives The percentage of shunt fraction significantly impacts the management of patients with congenital shunts, influencing strategic choices such as surgical or interventional procedures. This study compared the estimated shunt fraction (the ratio of pulmonary-to-systemic flow, Qp/Qs) for quantifying the left-to-right shunt in children with v...

High-risk coronary plaques (HRP) are characterized in clinical radiological imaging by the presence of low plaque attenuation, a napkin-ring sign (NRS), spotty calcifications (SC) and a positive remodeling index (RI). To evaluate if these signs are detectable in postmortem imaging by a multi-phase postmortem CT angiography (MPMCTA), a retrospective...

Background: Coronary CT angiography (CCTA) is increasingly used as a non-invasive tool to assess coronary artery disease (CAD). However, CCTA is subject to motion artifacts, potentially limiting its clinical utility. Despite faster (0.35 and 0.28 s/rot) gantry rotation times, low (60-65 bpm) heartbeat is recommended, and the use of β-blockers is o...

Objectives: To evaluate the diagnostic utility of multiphase postmortem CT angiography (PMCTA) to detect plaque enhancement as a surrogate marker of inflammation, using fatal coronary plaques obtained from autopsies following sudden cardiac death. Methods: In this retrospective study, we included 35 cases (12 women, 34%; median [IQR] age, 52 [11...

Novel Postmortem CT Angiography Shows Promise in Detecting Inflammation-Linked Plaques in Sudden Cardiac Death Victims Introduction: Researchers have made significant strides in evaluating coronary artery plaque enhancement and inflammation non-invasively in individuals who experienced a major cardiovascular event. This groundbreaking study sheds...

In this educational poster, we review the classifications and typical appearances of PVCS, as well as treatment options for different scenarios.

Background Pulmonary manifestations of COVID-19 pneumonia are well known. However, COVID-19 is also associated with a range of vascular manifestations such as embolism, congestion, and perfusion changes. Regarding congestion, research from different groups has suggested arteriovenous anastomosis dysregulation as a contributing factor. In this study...

Abstract Purpose Hypnosis is useful for diminishing distress during medical procedures. This study investigated the efficacy of virtually augmented self-hypnosis as an adjunctive nonpharmacological method for procedural pain and anxiety relief during endovascular interventions (EVI). Methods We compared an immersive distraction experience (clinical...

We enjoyed reading the review by Wand et al. about carotid plaque vulnerability recently published in Biomolecules and believe that some points could be further clarified. In particular, CT assessment of intraplaque hemorrhage has been regarded as a reliable test in some publications; however, the available evidence is scarce and challenged by cont...

In this paper, a wideband antenna is proposed for ultra-wideband microwave imaging applications. The antenna is comprised of a tapered slot ground, a rectangular slotted patch and four star-shaped parasitic components. The added slotted patch is shown to be effective in improving the bandwidth and gain. The proposed antenna system provides a realiz...

We aim to nuance the clinical apllicability and usefulness of intrapalque hemorrage and calcification assessment with CT in carotid arteries, focusing on current limitations and future studies.

Pelvic venous disorders (PeVD), sometimes referred to as pelvic congestion syndrome (PCS), widely impact affected patients–mainly young women’s quality of life, causing puzzling, uncomfortable symptoms sometimes requiring months or years to get an explanation, while simply remaining undiagnosed in other cases. Because pelvic pain is a non-specific...

Unlabelled: Noninvasive methods of estimating invasively measured fractional flow reserve (FFRinvasive ) are actively being explored, aiming to avoid the use of an invasive pressure wire and the administration of hyperemia-inducing drugs. Coronary angiography-derived FFR (FFRangio ) has already demonstrated its diagnostic performance in the contex...

Congenital coronary anomalies are among the rare disorders of the otherwise normal heart. A 2-year-old toddler was evaluated for de novo heart failure after a flu-like event 2 months before being suspicious of post-Covid-19 dilated cardiomyopathy. The cardiac magnetic resonance (CMR) technique displayed the basal to mid subendocardial to transmural...

Background: Selection of the transcatheter heart valve size for a mitral valve-in-valve procedure is based on the type and manufacturer's labelled size. However, accurate information of surgical heart valve (SHV) size may not be available in the patient's medical record. The purpose of this study is to establish reference data for computed tomogra...

PurposeTo evaluate the correlation between whole lung enhancement (WLE) and pulmonary blood volume (PBV) obtained through dual energy computed tomography pulmonary angiography (DECTPA) and echocardiography-derived systolic pulmonary arterial pressure (SPAP).Methods Sixty-eight patients who underwent DECTPA were enrolled in the study after giving in...

The term “cardiomegaly” is widely used in the chest radiography setting. However, this term tends to be also used in the chest CT scan exams. While it can be technically correct, it is inaccurate and clinically not useful. The heart can be more precisely analyzed on CT, as each cardiac chamber can be described individually.

Background: Vascular abnormalities, including venous congestion (VC) and pulmonary embolism (PE), have been recognized as frequent COVID-19 imaging patterns and proposed as severity markers. However, the underlying pathophysiological mechanisms remain unclear. In this study, we aimed to characterize the relationship between VC, PE distribution, an...

This preprint discusses pathophysiological mechanisms likely influencing blood clot distribution in COVID-19-related acute pulmonary embolism, taking into account both airspace disease and venous congestion.

Intracavitary electrocardiography is an accurate guidance technique for peripherally inserted central catheters (PICC) tip location that is spreading widely among providers using non x-ray-based facilities. The principle behind this technology relies on the transmission of the electrocardiographic signal at the tip of the catheter and its use as an...

Advances in computed tomography (CT) have resulted in a substantial increase in the size of datasets. We built a new concept of medical image compression that provides the best compromise between compression rate and image quality. The method is based on multiple contexts and regions-of-interest (ROI) defined according to the degree of clinical int...

Mortality rates associated with venous thromboembolism (VTE) are high. Inferior vena cava filters (IVCFs) have been frequently placed for these patients as part of their treatment, albeit the paucity of data showing their ultimate efficacy and potential risk of complications. Issues regarding long-term filter dwell time are accounted for in society...

Endovascular interventions (EVI) are increasingly performed as minimally-invasive alternatives to surgery and have many advantages, including a decreased need for general anesthesia. However, EVI can be stressful for patients and often lead to anxiety and pain related to the procedure. The use of local anesthetics, anxiolytics, and analgesic drugs...

Introduction Data regarding the prevalence of mesenteric artery stenosis in patients undergoing transcatheter aortic valve implantation (TAVI) are scarce. Whether patients with high-risk features for acute mesenteric ischemia (AMesI) have a worse prognosis compared with those without high-risk features is unknown. We aimed to address these question...

Coronary-pulmonary artery fistulas (CPAF) are congenital vascular anomalies detected incidentally in most cases. When a significant left-right shunt exists, surgical, or percutaneous treatment is indicated. We describe a challenging case of CPAF closure, by percutaneous approach, in a patient symptomatic for dyspnea and evidence of a significant le...

Background Nephrotic-range proteinuria is a common reason for nephrological consultation in clinical practice. The differential diagnosis is wide, and generally focuses on different forms of glomerulonephritis, but other causes should not be overlooked, as illustrated in this article. Case presentations We report two female patients with nephrotic...

Superior vena cava obstruction results from any limitation of blood flow through the superior vena cava. Circulation to the heart may persist through various collateral vessels whose development depends on the level of obstruction. Depending on the level and degree of occlusive disease, the severity of clinical symptoms may vary considerably, up to...

Composting is the most efficient technique for managing household organic waste; it is the most widely used technique in the world. To improve and accelerate the composting process and produce rich and stable compost, it is necessary to grind and shred organic waste into small pieces to facilitate the degradation of the material by microorganisms....

In this study, a novel design of smartphone endoscope adapter is introduced. The different parts of the proposed adapter are firstly designed in consideration of the use of flashlight smartphones as the light source in order to securely fit the endoscope with the smartphone. The entire system combining Smartphone and endoscope via this adapter is t...

Background Computed tomography angiography (CTA) is used to plan TAVI procedures. We investigated the performance of pre-TAVI CTA for excluding coronary artery disease (CAD). Methods In total 127 patients were included. CTA images were analyzed for the presence of ≥ 50% (significant CAD) and ≥ 70% (severe CAD) diameter stenoses in proximal coronar...

Purpose To evaluate the pathological nature of the radiological feature of “atherosclerotic plaque enhancement,” we compared computed tomography (CT) characteristics of fatal coronary plaques obtained from autopsies of sudden coronary death on post-mortem coronary computed tomography angiography (CCTA) with histological examination. Methods A retro...

The problem of household waste management is becoming more and more acute with the growth of economic development that the country of Morocco has experienced. Moreover, the management of this waste is a burden for the municipalities, in view of its cost, which is increasing with time. Therefore, in this work we present the design, the mechanical an...

We read with great interest the article published by Kakkos et al., which explores the management of venous thrombosis. We thank the expert panel for drawing up practical guidelines to help clinicians select appropriate management strategies and improve outcomes, however we have some comments about the section “Management of bleeding in patients on...

To the Editor: We enjoyed reading the systematic review recently published in CHEST (November 2020) by Adams et al.1 Based on 28 studies that included 3,466 patients, the authors analyzed known CT findings and structured the disease’s imaging signature. Expectedly, the most frequent pattern was ground glass opacity (81.0%), but more interesting was...

Purpose: We carried out this study to evaluate the predictive value of atherosclerosis burden score (ABS) to predict coronary artery disease (CAD) among asymptomatic patients without known cardiovascular disease (CVD), as compared to other imaging or functional techniques, namely coronary artery calcium (CAC) score, carotid intima-media thickness (...

Although vascular abnormalities are thought to affect coronavirus disease 2019 (COVID-19) patients’ outcomes, they have not been thoroughly characterized in large series of unselected patients. The Swiss national registry coronavirus-associated vascular abnormalities (CAVA) is a multicentric cohort of patients with severe acute respiratory syndrome...

Although vascular abnormalities are thought to affect COVID-19 patients outcomes, they have not been thoroughly characterized in large series of unselected patients. The Swiss National Registry COVID-CAVA is a multicentric cohort of patients with SARS-CoV-2 infection who underwent a clinically indicated chest computed tomography (CT) aiming to asse...

Atherosclerotic disease is currently one of the most important problems of modern medicine because it is a leading cause of increased morbidity, mortality, and disability in the Western World. Atherosclerosis of the lower limbs (peripheral arterial disease - PAD) significantly affects the quality of life and, in a considerable proportion of patient...

Objectives: To quantitatively evaluate the impact of virtual monochromatic images (VMI) on reduced-iodine-dose dual-energy coronary computed tomography angiography (CCTA) in terms of coronary lumen segmentation in vitro, and secondly to assess the image quality in vivo, compared with conventional CT obtained with regular iodine dose. Materials an...

OBJECTIVE. Coupled ECG-electromagnetic (EM) guidance shows promise for use in placement of peripherally inserted central catheters (PICCs) when compared with the classic blind technique. However, ECG-EM guidance has not been appropriately compared with the reference standard of fluoroscopy (FX) guidance. Here, we aimed to compare ECG-EM guidance wi...

To reduce inferior vena cava filter (IVCF) related complications, retrieval is recommended whenever possible. Nevertheless, IVCF retrieval rates remain lower than expected, likely due to insufficient follow-up after placement. We evaluated the value of a structured program designed to follow patients by the interventional radiology team up to 5 mon...

Up to now, COVID-19-related vascular changes were mainly described as thrombo-embolic events. A handful of researchers reported another type of vascular abnormality referred to as "vascular thickening" or "vascular enlargement," without specifying whether the dilated vessels are arteries or veins nor providing a physiopathological hypothesis. Our o...

Description of endovascular management of a traumatic pseudoaneurysm of the right pulmonary artery, in a 50-year-old man admitted with haemodynamic instability after a ski fall.

Up to now, COVID-19-related vascular changes were mainly described as thrombo-embolic events. A handful of researchers reported another type of vascular abnormality referred to as "vascular thickening" or "vascular enlargement," without specifying whether the dilated vessels are arteries or veins nor providing a physiopathological hypothesis. Our o...

Chronic thromboembolic pulmonary hypertension (CTEPH) is a potentially fatal and frequently undiagnosed form of pulmonary hypertension (PH), classified within group 4 by the World Health Organization (WHO). It is a type of precapillary PH, which uncommonly develops as a peculiar sequel of acute pulmonary embolism due to the partial resolution of th...

Congenital venous malformations (VMs) are the most common vascular abnormalities. Their treatment can be complex, depending on their size and surrounding tissues involvement. To date, sclerotherapy is considered the gold standard for the treatment of VMs. This technique, which aims to destroy the endothelium and thus cause fibrosis and retraction o...

Pulmonary artery catheter (PAC) insertion in patients with severe pulmonary hypertension, right heart dilation and failure, is very challenging. Misplacement and knotting are rare but could be serious complications leading to a delay of the monitoring and sometimes an emergent not expected intervention. Here we report a case of a patient admitted t...

Background. Coronavirus disease 2019 (COVID-19) can result in profound changes in blood coagulation. The aim of the study was to determine the incidence and predictors of venous thromboembolic events (VTE) among patients with COVID-19 requiring hospital admission. Subjects and Methods. We performed a retrospective study at the Lausanne University H...

Objectives: Current guidelines recommend prophylactic replacement of the ascending aorta at an aneurysmal diameter of >55 mm to prevent acute Type A aortic dissection (TAAD) in non-Marfan patients. Several publications have challenged this threshold, suggesting that surgery should be performed in smaller aneurysms to prevent this devastating disea...

Abstract Background: Several well-established factors, including right ventricular dilatation and elevated troponins, identify pulmonary embolism (PE) patients at risk of fatal outcome. On the other hand, identifying low-risk patients might help increase early discharge from the emergency department. Purpose: To investigate the prognostic value of...

Purpose: To investigate the prognostic value of an integrative approach combining clinical variables and the Qanadli CT obstruction index (CTOI) in patients with nonmassive acute pulmonary embolism (PE). Materials and Methods: This retrospective study included 705 consecutive patients (mean age, 63 years; range, 18–95 years) with proven PE. Clot bu...

Objectives: To report a new classification scheme for acute aortic dissection (AAD) that considers the aortic arch as a separate entity and integrates patterns of malperfusion syndrome (MPS). The proposed classification was evaluated retrospectively in a large population. Materials and Methods: We retrospectively reviewed pre-therapy CT angiograms...

Free fulltext: https://www.thrombosisresearch.com/article/S0049-3848(20)30170-5/ • Patients having COVID-19 pneumonia are at risk of venous thromboembolism. • Prophylaxis versus anticoagulation for severely ill patients is currently debated. • No specific guidelines for the management of severe pulmonary embolism exist. • Endovascular pulmonary em...

Disturbed coagulation in COVID-19 has been identified as a significant indicator of poor prognosis, and recent reports attempted to understand COVID-19-related coagulopathy and raised awareness of acute pulmonary embolism (PE) events. Because COVID-19 pneumonia is associated with an increased thromboembolic risk, thrombotic prophylaxis is recommend...

https://www.frontiersin.org/articles/10.3389/fcvm.2020.00068/ *Objectives To prospectively compare three image acquisition techniques in lower extremity CT angiography: the “standard” anterograde technique (SA), the adaptive anterograde technique (AA), and the retrograde acquisition technique (RA). Materials and Methods Sixty consecutive patients w...

Given the importance of continuum in providing services and exigence of protecting health care professionals during this period, the Swiss Society of Vascular and Interventional Radiology (SSVIR) is releasing guidance for interventional radiologists as preparedness to manage COVID-19 patients, the workflow of non-COVID-19 patients and optimize inte...

Link: https://www.thrombosisresearch.com/article/S0049-3848(20)30119-5/fulltext *Objective To raise awareness for possible benefits of examining known COVID-19 patients presenting sudden clinical worsening with CT pulmonary angiography instead of standard non-contrast chest CT. Highlights • Patients having COVID-19 pneumonia are at risk of coagulo...

Background In the era of High-sensitive troponin (hs-Tn), up to 50% of patients with a mild increase of hs-Tn will finally have a normal invasive coronary angiogram. Fractional Flow Reserve (FFR) derived from coronary computed tomographic angiography (FFR-CT) has never been used as a non-invasive tool for the diagnosis of coronary artery disease in...

Full text: https://pubs.rsna.org/doi/full/10.1148/ryct.2020200161

This article describes the feasibility of using smartphones as an alternative light source in endoscopic procedures by comparing it to conventional light sources. Therefore, we used an adapter designed and printed in 3D, combined with an iPhone 6S, ear endoscope L. 50mm diam. 4mm 0 ° and a cardboard as dark anterior. Tests have shown that the illum...

Background: inferior vena cava filters (IVCF) are widely used to prevent thromboembolic events in patients not suitable for anticoagulation (AC). Although new generations of filters are optional and therefore retrievable, most of them become permanent. Aim of our study was to evaluate real life IVCF management in a tertiary hospital including retr...

In the above-named work (IEEE Trans. Fuzzy Syst., vol. 20, no. 2, pp. 224-234, Apr. 2012), the branch name of Islamic Azad University in the affiliation of R. Hosseini and M. Mazinani appeared incorrectly. It should have read as the "Shahr-e-Qods Branch."

Background: Clavicular fracture or sternoclavicular luxation is observed in 10% of all polytrauma patients and is frequently associated with concomitant intrathoracic life-threatening injuries. Posterior sternoclavicular luxation is well known to induce underlying great vessels damage. The gold standard treatment usually is a combined orthopedic a...

This article aims to clarify the value of cardiac CT as well as its new applications in the different areas of cardiology for both diagnosis and pretreatment evaluation, including stable coronary artery disease, acute coronary syndrome, valvular disease and the functional and morphological evaluation of the heart.

Objectives: To assess interobserver variability between a trained radiology technician (RT) and an experienced radiologist in arterial obstruction quantification using the Qanadli obstruction index (QOI), in patients diagnosed with acute pulmonary embolism (APE) at CT pulmonary angiography (CTPA). Materials and Methods: A RT and a radiologist inde...

The use of smartphone in healthcare field is increasing, in particular within the field of endoscopy that usually involves expensive and often cumbersome equipment. The objective is to offer a novel adapter connected to the smartphone with modern endoscopes, exploiting the camera for viewing and recording. The design and operation are described in...