Sajid Maqsood

Sajid Maqsood
United Arab Emirates University | UAEU · Department of Food Nutrition and Health

PhD, PDF

About

147
Publications
59,505
Reads
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4,483
Citations
Citations since 2016
99 Research Items
3915 Citations
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201620172018201920202021202202004006008001,0001,200
201620172018201920202021202202004006008001,0001,200
201620172018201920202021202202004006008001,0001,200
Introduction
Dr. Sajid is a Professor in Department of Food Nutrition and Health, UAEU. My current research at UAEU is focused on Food by-product bioactive compounds and their nutraceutical properties, encapsulation and food applications. I have established an innovative research program at UAEU which focus on bioactive molecules in camel milk and dates, investigating their functional and nutraceutical properties, and their encapsulation at micro and nano level.
Additional affiliations
August 2017 - September 2020
United Arab Emirates University
Position
  • Head of Faculty
August 2011 - August 2016
United Arab Emirates University
Position
  • Professor (Assistant)
October 2008 - December 2010
Prince of Songkla University
Position
  • Researcher

Publications

Publications (147)
Article
Full-text available
The processing industry discards avocado seeds, which increases production and ultimately pollutes the environment. It would be advantageous to handle these waste by-products both economically and environmentally. Avocado seeds are rich in polysaccharides, proteins, lipids, vitamins, minerals, and other bioactive substances. The nutritional and phy...
Article
Camel skin gelatin hydrolysate (CSGH) was prepared using different proteolytic enzymes [alcalase (A), protease (P), and combination (AP)], hydrolysis time (2, 4, and 6h) and enzyme: substrate (E/S) ratio (1, 3, and 5 %). In general, the degree of hydrolysis (DH) increased with increasing hydrolysis time for all enzyme treatments. CSGHs generated wi...
Article
Over the decade, fish protein-derived peptides (FPDP) have been evaluated for various biological activities including their mechanism of action through structure-activity relationship (SAR) and molecular simulation. SAR studies are known to provide the basic structural information of the active site which can be used for designing synthetic bioacti...
Article
Full-text available
Citrullus colocynthis (Colocynth) has originated a great interest in their applications as indigenous medicine and as a functional food ingredient. The intact colocynth seed protein was enzymatically hydrolysed using proteolytic enzymes alcalase, bromelain, and chymotrypsin at different time intervals of 3, 6, and 9 h. The highest degree of hydroly...
Article
Full-text available
The green extraction of bioactive compounds from date seeds was investigated using seven natural deep eutectic solvents (NADES) coupled with ultrasound-assisted extraction (UAE). The seven NADESs mainly consisted of choline chloride as hydrogen bond acceptors (HBA) and four sugars, two organic acids, and one polyalcohol as hydrogen bond donors (HBD...
Article
Millets are well‐known for protein with high nutritional value and a range of health benefits. Millet‐derived protein can thus be a rich source of bioactive peptides with multiple bioactive properties. In this study three proteolytic enzymes i.e. alcalase, bromelain, and chymotrypsin were used to generate pearl millet protein hydrolysates (PMPHs) a...
Article
Full-text available
Lactobacillus reuteri fortified camel milk infant formula (CMIF) was produced. The effect of encapsulation in different matrices (sodium alginate and galacto-oligosaccharides) via spray drying, simulated infant gastrointestinal digestion (SIGID), and storage conditions (temperature and humidity) on the viability of L. reuteri in CMIF and the physic...
Article
The present study aims to investigate the digestive process (gastric and intestinal phases) effects on the survivability of total and individual phenolic compounds, and the in vitro health-related bioactive properties of four high-quality and commonly consumed dates (Phoenix dactylifera) varieties (Safawi, Khalas, Khudri, and Booman). Phenolic comp...
Conference Paper
Camel whey-quercetin conjugates were fabricated via free radicals using a combination of ultrasonication treatment and a redox-pair (ascorbic acid/H2O2). Conjugation of whey with quercetin was confirmed using UV-Vis. spectroscopy, FTIR and SDS-PAGE. UV-Visible spectroscopy showed a bathochromic shift and appearance of a hump around ≈350 nm (absent...
Conference Paper
Hypercholesterolemia and hypertension are major growing concerns that are managed by drugs that inhibit various metabolic enzymes. Milk hydrolysates have been reported to contain various bioactive peptides (BAP) that can inhibit various metabolic enzymes for enhancing human health. As such camel whey proteins were subjected to peptic hydrolysis usi...
Article
Background: Whey proteins and their peptide derivatives have attracted a great attention of researchers in the pharmaceutical and nutritional fields, due to their numerous bio-functionalities. Aim: In the present research study, enzymatic protein hydrolysates (CWPHs) from camel whey proteins (CWPs) were produced and investigated for their antioxida...
Article
This study aims to investigate the potentials of mature (MSPHs) and young (YSPHs) soybean enzymatic protein hydrolysates for the inhibition of pancreatic lipase (PL) and cholesterol esterase (C-Ease) enzymes. Higher proteins degradation levels were recorded with Bromelain compared to Flavourzyme and Alcalase, and upon hydrolysis, improved PL and C-...
Article
Full-text available
In this study, the synthesis of date seed nanoparticles (SNPs) was investigated using the acid hydrolysis method. Afterwards, the potential extraction of phenolics from the synthetized SNP using microwave was studied using water and methanol as recovery solvents. To accomplish this, the experiments were operated at different conditions following th...
Article
Full-text available
This study aimed to explore the effect of enzymatic hydrolysis conditions (enzyme types and hydrolysis time) of date seed protein hydrolysates (DSPH) on in-vitro inhibition of molecular markers related with diabetic and hypercholesteremia. The DSPH was prepared using alcalase, bromelain, papain, and protease at different hydrolysis time (HT) (2, 4...
Article
Nowadays, during the current COVID-19 pandemic, consumers increasingly seek foods that not only fulfill the basic need (i.e., satisfying hunger) but also enhance human health and well-being. As a result, more attention has been given to some kinds of foods, termed "superfoods," making big claims about their richness in valuable nutrients and bioact...
Article
Full-text available
In this study, the microwave-assisted processing of Sesamum indicum leaves was intensified to predict the total alkaloid content via Taguchi orthogonal design and neural network model. Under the optimum microwave condition, the maximized alkaloid content was estimated to be 15.40 (mg/g) % using irradiation time (A) of 60 sec, microwave power (B) of...
Article
Full-text available
Camel milk (CM) constitutes an important dietary source in the hot and arid regions of the world. CM is a colloidal mixture of nutritional components (proteins, carbohydrates, lipids, vitamins, and minerals) and non-nutritional components (hormones, growth factors, cytokines, immunoglobulins, and exosomes). Although the majority of previous researc...
Article
Background: Manilkara zapota, also known as Sapodilla, is the best-known and most widely cultivated fruit from Sapotaceae. Sapodilla is a rich source of nutrients (sugars, acids, protein, amino acids), minerals (potassium, calcium, and iron), and comprises of a myriad of bioactive compounds, which are chiefly composed of ellagitannins, gallotannins...
Article
Ultrasonic technology presents a promising novel tool in the food industry for the processing of milk and dairy products. In this study, we investigated the effects of ultrasonication (US) as an alternative to thermal pasteurization for stabilization of the bioactive properties of camel milk. Camel and bovine milk samples were subjected to US at 6...
Article
Full-text available
Date seeds from the date palm fruit are considered as a waste and they are known to contain several bioactive compounds. Producing nanoparticles from the date seeds can enhances their effectiveness and their utilization as novel functional food ingredients. In this study, date seed nanoparticles (DSNPs) synthesized using acid (HCl) hydrolysis metho...
Article
The development of novel protein sources to compensate for the expected future shortage of traditional animal proteins due to their high carbon footprint is a major contemporary challenge in the agri-food industry currently. Therefore, both industry and consumers are placing a greater emphasis on plant proteins as a sustainable source of protein to...
Article
Full-text available
Bioactive compounds exhibit numerous health benefits; however, they are highly sensitive to degradation under various process conditions. Applications of these compounds are limited in food and pharmaceutical products due to their quick release, low solubility, possible interactions with other ingredients, and reduced biological potential. Encapsul...
Article
Full-text available
The effect of defatting and bleaching of camel skin on gel-forming, structural, and interfacial properties of extracted gelatin was studied. Gelatin defatted for 6 h and bleached for 48 h (48BD-6 h) gave the highest yield (28.44%) while gelatin bleached for 24 h (24BC) gave the highest gel strength (423.3 g). Electrophoretic analysis showed that al...
Article
Full-text available
Camel milk (CM) is known for its beneficial virtues in the human diet and health. This includes its antidiabetic properties demonstrated in many in vitro and in vivo studies. Nevertheless, the scientific rationale behind the molecular and cellular basis of such beneficial effects and the exact antidiabetic agent(s)/mechanism(s) are still elusive. I...
Article
Lotus is a member of a small family of Nelumbonaceae and is regarded as a sacred flower grown as a freshwater aquatic plant. All plant parts are utilized as food and medicine. Lotus seed (LS) is an important part of the lotus plant due to its nutritional and bioactive components. The presence of phenolic compounds imparts numerous bioactivities to...
Article
Fish processing industries result in an ample number of protein‐rich byproducts, which have been used to produce protein hydrolysate (PH) for human consumption. Chemical, microbial, and enzymatic hydrolysis processes have been implemented for the production of fish PH (FPH) from diverse types of fish processing byproducts. FPH has been reported to...
Article
Full-text available
The ‘Khenizi’ date palm is one of the most recognized date palm cultivars. It is commonly consumed at the Bisr, Rutab, and Tamr stages of ripening; however, the fruit has a short shelf/storage life at this stage of maturity even with refrigeration. Preharvest application of a natural elicitor chitosan (Ch) has been reported to have positive influen...
Article
Camel milk has been regarded as a potential nutritional and therapeutic food source across various arid and semi-arid regions. Camel milk composition is comparable to cow milk with predominant medium-chain fatty acids in fat, low lactose, and abundant vitamin C and iron. Consumption of camel milk and its products are presumed to be associated with...
Article
Cow (CwC) and camel casein (CaC) hydrolysates were generated using Alcalase™ (CwCA and CaCA) and Pronase-E (CwCP and CaCP) each for 3 and 6 h, and investigated for their potential to inhibit key lipid digesting enzymes i.e., pancreatic lipase (PL) and cholesteryl esterase (CE). Results revealed stronger PL and CE inhibition by CaC hydrolysates comp...
Article
This study aimed to appraise the effects of probiotics (Pediococcus pentosaceus) microencapsulation on their stability and survivability in Chami (Cheese) as carrier matrix. Thus, camel milk proteins and wheat starch were used as wall materials for probiotics microencapsulation. The results showed that upon encapsulation, the bacterial death cycles...
Article
Full-text available
Date (Phoenix dactylifera L. Arecaceae) fruits and their by-products are rich in nutrients. The health benefits of dates and their incorporation into value-added products have been widely studied. The date-processing industry faces a significant sustainability challenge as more than 10% (w/w) of the production is discarded as waste or by-products....
Article
Full-text available
Lotus is a member of a small family of Nelumbonaceae and is regarded as a sacred flower grown as a freshwater aquatic plant. All plant parts are utilized as food and medicine. Lotus seed (LS) is an important part of the lotus due to its nutritional and bioactive components. The presence of phenolic compounds imparts numerous bioactivities to the LS...
Article
Full-text available
Probiotics have received increased attention due to their nutritional and health-promoting benefits. However, their viability is often impeded during food processing as well as during their gastrointestinal transit before reaching the colon. In this study, probiotic strains Lactobacillus rhamnosus MF00960, Pediococcus pentosaceus MF000967, and Lact...
Article
Full-text available
Camel meat is an ethnic food consumed across the arid regions of Middle East and North-East Africa. It can be a potential alternative red meat for human consumption worldwide. Camel meat is nutritionally as good as any conventional meat source, in fact has an edge over beef or lamb due to its low intramuscular fat, low cholesterol content, and high...
Article
Full-text available
Bioactive peptides derived from milk proteins are widely known to possess antibacterial activities. Even though the antibacterial effects of milk-derived peptides are widely characterized, not much focus is given to their antifungal characterization. Therefore, in this study, we investigated the antifungal properties of camel and cow whey and casei...
Article
Full-text available
Lactoferrin (LF) is a milk protein that may be an interesting candidate for the antidiabetic properties of milk due to its well-documented bioactivity and implication in diabetes. Here, we investigated the functional action of LF purified from camel and bovine milk (cLF, bLF) on insulin receptors (IR) and their pharmacology and signaling in hepatoc...
Article
The study reports formulation, characterization and in-vitro digestion of novel camel milk-based infant formula (IF) in comparison to bovine and commercial IF. Camel milk IF was further fortified with camel casein or whey at different levels to study the effect of different protein supplementation. A simulated infant gastrointestinal digestion (SIG...
Article
Full-text available
Human diet is undergoing a shift towards plant-based diet as a sustainable source of protein compared to animal-derived protein. In this study, cholesterol esterase (CEase) and pancreatic lipase (PL) inhibitory activities of amaranth protein hydrolysates (APHs) were studied. Bromelain, chymotrypsin, and actinase E were used for generating APHs at 2...
Article
Full-text available
Ultrasonication, redox-pair generated free radical method and their combination (Ultrasonication/redox-pair method) was used for production of camel whey-quercetin conjugates. FTIR and SDS-PAGE confirmed successful production of whey-quercetin conjugates using ultrasonication and ultrasonication/redox-pair method. FTIR suggested existence of covale...
Article
The generation of camel milk derived bioactive peptides (CMPs) have started to grab keen interest of many researchers during the past decade. CMPs have shown more significant bioactive properties in comparison to camel milk intact proteins. CMPs can be obtained using enzyme hydrolysis to form hydrolysates, or by the fermentation process. In this sy...
Article
Consumer awareness of the relationship between health and nutrition has caused a substantial increase in the demand for nutraceuticals and functional foods containing bioactive compounds (BACs) with potential health benefits. However, the direct incorporation of many BACs into commercial food and beverage products is challenging because of their po...
Article
Full-text available
The accumulation of high amounts of petro-based plastics is a growing 20 environmental devastation issue, leading to the urgent need to innovate eco-safe pack-21 aging materials at an equivalent cost to save the environment. Among different substi-22 tutes, starch-based types and their blends with biopolymers are considered an innovative 23 and sma...
Article
Dietary habits and lifestyle-related diseases indicate that food has a direct impact on individual health. Hence, a diet containing essential nutrients is important for healthy living. Fish and fish products are important in diets worldwide because of their nutritional value, especially their easily digestible proteins with essential amino acids. S...
Article
Full-text available
“Barhi” date fruit is highly appreciated and widely consumed at the Bisr stage (first edible stage) of maturity. However, maintaining its quality for long periods of time after harvest and throughout marketing is a substantial challenge. Therefore, the objective of this study was to investigate the effects of preharvest spray treatments of 1% chito...
Article
The health and environmental concerns are provoking changes in human diets and plant-based proteins are being considered as sustainable source of proteins compared to animal-derived proteins. In line with this, the current study investigated amaranth protein isolate (API) and hydrolysates (APHs) for in-vitro angiotensin-I converting enzyme (ACE), d...
Article
Full-text available
Optimum conditions for high-quality gelatin recovery from camel skin and its molecular, structural, and rheological characterization were carried out in this study. Increased yield and gel strength were recorded, with an increase in camel skin pretreatment times of 6 to 42 h and 0.50 and 0.75 M-NaOH. Gelatin from skin pretreated with 0.75 and 0.5 M...
Article
Full-text available
Despite the immense capabilities of the date palm, maintaining the fruit’s quality, marketability, and shelf life is still a challenge. This study aimed to assess the synergistic effect of a preharvest spray application of a natural elicitor chitosan, (Ch) 1% alone and in combination with salicylic acid (SA) 2 mM and calcium chloride (Ca) 3%; (Ch,S...
Article
Whey proteins are widely used as functional ingredients in various food applications owing to their emulsifying, foaming, and gelling properties. However, their functional attributes are limited in some applications because of the dependence of their performance on pH, mineral levels, and temperature. Several approaches have been investigated to en...
Article
Novel antihypercholesterolemic bioactive peptides (BAP) from peptic camel whey protein hydrolysates (CWPH) were generated at different time, temperature, and enzyme concentration (%). Hydrolysates showed higher pancreatic lipase- (PL; except 3 CWPH) and cholesterol esterase (CE)-inhibiting potential, as depicted by lower half maximal inhibitory con...
Article
Full-text available
Camel milk has been gaining immmense importance due to high nutritious value and medicinal properties. Peptides from milk proteins is gaining popularity in various therapeutics including human cancer. The study was aimed to investigate the anti-cancerous and anti-inflammatory properties of camel whey protein hydrolysates (CWPHs). CWPHs were generat...
Article
Beetroot is well known for its deep red-purple colouring pigments called betalains. Betalains also found its application in the preparation of functional foods and drinks. Therefore, extraction of pigments with higher recovery and stability is the prime need for the industry. Conventional extraction techniques such as maceration, grinding or pressi...
Chapter
Diet is one of the environmental factors that is recognized to impact our health and the emergence of certain diseases. During gastrointestinal digestion, the major nutrient protein consumed undergoes breakdown and releases several peptides and amino acids. Some of these peptides may act as hormones or neurotransmitters due to their similar charact...
Chapter
Bioactive peptides are defined as fractions of proteins, which have a specific sequence that has a positive physiological effect and may influence health (Kitts and Weiler 2003). The structure of bioactive peptides consists of amino acids linked together by covalent (or also known as peptide) bonds, and an overall lower molecular weight compared to...
Article
This study reports the angiotensin converting enzyme (ACE) inhibiting potential of peptic camel whey hydrolysates (WHs) produced under different hydrolysis conditions. WHs displayed ACE inhibitory IC50 value in the range of 0.197 to 1.307 mg/mL. Among 27 hydrolysates generated, four, with the lowest IC50, were subjected to peptide sequencing using...
Article
Camel milk proteins are an important substrate for bioactive peptides generation. This study investigates in-vitro antidiabetic effect (via inhibition of α-amylase (AA), α-glucosidase (AG) and dipeptidyl peptidase IV (DPP-IV)) of bovine (BC) and camel casein (CC) hydrolysates. Further, effect of simulated gastrointestinal digestion (SGID) on inhibi...
Chapter
Micro/nanoencapsulation is a promising technique to encapsulate/protect sensitive ingredients during various processing conditions and to enhance product value. Various techniques and additives are used for encapsulation such as emulsification, melt dispersion technology, extrusion, hydrogels, membrane and microchannel emulsification, and others. I...
Article
This study explores the inhibitory properties of camel whey protein hydrolysates (CWPH) toward α-amylase (AAM) and α-glucosidase (AG). A general full factorial design (3 × 3) was applied to study the effect of temperature (30, 37, and 45°C), time (120, 240, and 360 min), and enzyme (pepsin) concentration (E%; 0.5, 1, and 2%). The results showed tha...
Article
Full-text available
The molecular basis of the anti-diabetic properties of camel milk reported in many studies and the exact active agent are still elusive. Recent studies have reported effects of camel whey proteins (CWP) and their hydrolysates (CWPH) on the activities of dipeptidyl peptidase IV (DPP-IV) and the human insulin receptor (hIR). In this study, CWPH were...
Article
This study investigated the effect of camel milk protein hydrolysates (CMPH) at 100, 500 and 1,000 mg/kg of body weight (BW) for 8 wk on hyperglycemia, hyperlipidemia, and associated oxidative stress in streptozotocin-induced diabetic rats. Body weights and fasting blood glucose levels were observed after every week until 8 wk, and oral glucose tol...
Article
The study aimed to characterize and identify anti-diabetic and anti-hypertensive bioactive peptides generated upon enzymatic hydrolysis of quinoa protein isolates. Different quinoa protein hydrolysates (QPHs) were produced using food grade enzymes like Bromelain, chymotrypsin and Pronase E at a hydrolysis interval of 2 h up to 6 h. QPHs were charac...
Article
The major challenge addressed in this study was to explore the effect of various extraction conditions for gelatin recovered from camel skin and investigate the effect on microstructural, rheological, gelation and interfacial properties. The results revealed that yield of gelatin extracted at high temperature (70 °C) was higher than that of gelatin...
Article
Novel bioactive peptides from camel milk protein hydrolysates (CMPH) were identified and tested for inhibition of cholesterol esterase (CEase), and their possible binding mechanisms were elucidated by molecular docking. Papain-generated CMPH showed the highest degree of hydrolysis. All CMPH produced upon enzymatic degradation demonstrated a dramati...
Article
Date palm is an important fruit bearing tree grown widely in the arid and semi-arid regions of the world. The date fruit and its by-products, such as seeds, have both nutritional and medicinal value. However, date fruit and seeds have not been fully considered as potential functional food ingredients to develop foods with promising health benefits....
Chapter
Full-text available
The potential role of ω-3 polyunsaturated fatty acids (PUFAs) in preventing cardiovascular (CV) disease has been studied for decades. Docosaexaenoic acid (DHA), eicosapentaenoic acid (EPA), and alpha-linolenic acid (ALA) are known to be most important ω-3 PUFAs for their beneficial roles in human health. The American Heart Association has recommend...
Article
Camel milk protein hydrolysates (CMPHs) were investigated for anti-hypertensive and anti-inflammatory activities using in-vitro assays. CMPHs with potent ACE inhibitory and anti-inflammatory activities were subjected to peptide identification and their possible binding mechanism to ACE were depicted via molecular docking. Papain generated CMPHs sho...
Article
This study investigates the efficiency of starch nano-particles in comparison with native starch for encapsulation of probiotic bacterial cells (Pediococcus acidolactici). Bacterial cell-death after encapsulation, viability and bioactivity retention under simulated gastro-intestinal conditions (SGID)were studied. Encapsulation in native starch show...